NO322479B1 - IL-6 mutein, fremgangsmate for fremstilling av muteinet, DNA-molekyl som koder for muteinet, samt vektor og vertscelle som inneholder DNA-molekylet og farmasoytisk blanding som omfatter muteinet. - Google Patents

IL-6 mutein, fremgangsmate for fremstilling av muteinet, DNA-molekyl som koder for muteinet, samt vektor og vertscelle som inneholder DNA-molekylet og farmasoytisk blanding som omfatter muteinet. Download PDF

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Publication number
NO322479B1
NO322479B1 NO19984697A NO984697A NO322479B1 NO 322479 B1 NO322479 B1 NO 322479B1 NO 19984697 A NO19984697 A NO 19984697A NO 984697 A NO984697 A NO 984697A NO 322479 B1 NO322479 B1 NO 322479B1
Authority
NO
Norway
Prior art keywords
mutein
human
polypeptide
vector
cells
Prior art date
Application number
NO19984697A
Other languages
English (en)
Norwegian (no)
Other versions
NO984697L (no
NO984697D0 (no
Inventor
Marc Ehlers
Stefan Rose-John
Joachim Grotzinger
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Publication of NO984697L publication Critical patent/NO984697L/no
Publication of NO984697D0 publication Critical patent/NO984697D0/no
Publication of NO322479B1 publication Critical patent/NO322479B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5412—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Details Of Television Scanning (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Amplifiers (AREA)
NO19984697A 1996-04-09 1998-10-08 IL-6 mutein, fremgangsmate for fremstilling av muteinet, DNA-molekyl som koder for muteinet, samt vektor og vertscelle som inneholder DNA-molekylet og farmasoytisk blanding som omfatter muteinet. NO322479B1 (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
PCT/EP1996/001506 WO1997038103A1 (en) 1996-04-09 1996-04-09 Il-6 mutein
CA002251355A CA2251355C (en) 1996-04-09 1996-04-09 Il-6 mutein
CN96180247A CN1131309C (zh) 1996-04-09 1996-04-09 白细胞介素－6突变蛋白
PCT/EP1997/001736 WO1997038104A1 (en) 1996-04-09 1997-04-08 Il-6 mutein

Publications (3)

Publication Number Publication Date
NO984697L NO984697L (no) 1998-10-08
NO984697D0 NO984697D0 (no) 1998-10-08
NO322479B1 true NO322479B1 (no) 2006-10-09

Family

ID=27170853

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19984697A NO322479B1 (no) 1996-04-09 1998-10-08 IL-6 mutein, fremgangsmate for fremstilling av muteinet, DNA-molekyl som koder for muteinet, samt vektor og vertscelle som inneholder DNA-molekylet og farmasoytisk blanding som omfatter muteinet.

Country Status (18)

Country Link
US (1) US6280975B1 (de)
EP (1) EP0907737B1 (de)
JP (1) JP4189866B2 (de)
CN (1) CN1131309C (de)
AT (1) ATE291087T1 (de)
AU (1) AU728267B2 (de)
BR (1) BR9708648B1 (de)
CA (1) CA2251355C (de)
DE (1) DE69634497T2 (de)
DK (1) DK0907737T3 (de)
EA (1) EA000852B1 (de)
ES (1) ES2238690T3 (de)
FI (1) FI982198L (de)
IL (1) IL126484A0 (de)
NO (1) NO322479B1 (de)
PT (1) PT907737E (de)
UA (1) UA72426C2 (de)
WO (2) WO1997038103A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE383875T1 (de) 1998-03-17 2008-02-15 Chugai Pharmaceutical Co Ltd Prophylaktische oder therapeutische mittel gegen entzündliche erkrankungen des verdauungstraktes enthaltend antagonistische il-6 rezeptor antikörper
KR20060119412A (ko) * 2005-05-20 2006-11-24 아주대학교산학협력단 ＩＬ-6 발현 억제를 위한 ｓｉＲＮＡ 및 이를 함유하는조성물
US8522915B2 (en) * 2007-12-19 2013-09-03 Westerngeco L.L.C. Method and system for selecting parameters of a seismic source array
CN102101885B (zh) * 2010-09-01 2013-06-05 南京发士达生物科技有限公司 低诱导抑制性t细胞的人白细胞介素ⅱ突变体及其用途

Also Published As

Publication number Publication date
BR9708648A (pt) 1999-08-03
EA000852B1 (ru) 2000-06-26
CA2251355A1 (en) 1997-10-16
US6280975B1 (en) 2001-08-28
PT907737E (pt) 2005-05-31
FI982198A0 (fi) 1998-10-09
HK1019770A1 (en) 2000-02-25
AU728267B2 (en) 2001-01-04
UA72426C2 (en) 2005-03-15
JP4189866B2 (ja) 2008-12-03
CA2251355C (en) 2009-06-09
BR9708648B1 (pt) 2011-02-08
WO1997038103A1 (en) 1997-10-16
EA199800914A1 (ru) 1999-04-29
WO1997038104A1 (en) 1997-10-16
EP0907737A1 (de) 1999-04-14
NO984697L (no) 1998-10-08
FI982198A7 (fi) 1998-10-09
FI982198L (fi) 1998-10-09
ES2238690T3 (es) 2005-09-01
CN1216063A (zh) 1999-05-05
ATE291087T1 (de) 2005-04-15
CN1131309C (zh) 2003-12-17
AU5686496A (en) 1997-10-29
JP2000508164A (ja) 2000-07-04
NO984697D0 (no) 1998-10-08
DK0907737T3 (da) 2005-06-27
IL126484A0 (en) 1999-08-17
EP0907737B1 (de) 2005-03-16
DE69634497D1 (de) 2005-04-21
DE69634497T2 (de) 2006-01-26

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