NO324089B1 - Hybrid nukleinsyremolekyl for fremstilling av lipiderte rekombinante proteiner fra Borrelia-arter. - Google Patents

Hybrid nukleinsyremolekyl for fremstilling av lipiderte rekombinante proteiner fra Borrelia-arter. Download PDF

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Publication number
NO324089B1
NO324089B1 NO19975619A NO975619A NO324089B1 NO 324089 B1 NO324089 B1 NO 324089B1 NO 19975619 A NO19975619 A NO 19975619A NO 975619 A NO975619 A NO 975619A NO 324089 B1 NO324089 B1 NO 324089B1
Authority
NO
Norway
Prior art keywords
nucleic acid
lipoprotein
acid sequence
recombinant
protein
Prior art date
Application number
NO19975619A
Other languages
English (en)
Norwegian (no)
Other versions
NO975619L (no
NO975619D0 (no
Inventor
Lorne Franklin Erdile
Robert S Becker
Robert C Huebner
Donald J Warakomski
Maryann B Gray
Derek L Pyle
Original Assignee
Connaught Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Connaught Lab filed Critical Connaught Lab
Publication of NO975619D0 publication Critical patent/NO975619D0/no
Publication of NO975619L publication Critical patent/NO975619L/no
Publication of NO324089B1 publication Critical patent/NO324089B1/no

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/205—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Campylobacter (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO19975619A 1995-06-07 1997-12-04 Hybrid nukleinsyremolekyl for fremstilling av lipiderte rekombinante proteiner fra Borrelia-arter. NO324089B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US48637395A 1995-06-07 1995-06-07
US47578195A 1995-06-07 1995-06-07
PCT/IB1996/000633 WO1996040718A1 (en) 1995-06-07 1996-06-05 Expression of lipoproteins

Publications (3)

Publication Number Publication Date
NO975619D0 NO975619D0 (no) 1997-12-04
NO975619L NO975619L (no) 1998-01-30
NO324089B1 true NO324089B1 (no) 2007-08-13

Family

ID=27044930

Family Applications (2)

Application Number Title Priority Date Filing Date
NO19975619A NO324089B1 (no) 1995-06-07 1997-12-04 Hybrid nukleinsyremolekyl for fremstilling av lipiderte rekombinante proteiner fra Borrelia-arter.
NO20064621A NO20064621L (no) 1995-06-07 2006-10-09 Ekspresjon av lipoproteiner.

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO20064621A NO20064621L (no) 1995-06-07 2006-10-09 Ekspresjon av lipoproteiner.

Country Status (13)

Country Link
EP (2) EP0832093B1 (de)
JP (1) JP4091112B2 (de)
AT (1) ATE339436T1 (de)
AU (1) AU721954B2 (de)
CA (2) CA2704354A1 (de)
DE (1) DE69636544T2 (de)
DK (1) DK0832093T3 (de)
ES (1) ES2271954T3 (de)
FI (1) FI974422L (de)
IL (1) IL118578A (de)
NO (2) NO324089B1 (de)
PT (1) PT832093E (de)
WO (1) WO1996040718A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7008625B2 (en) 1993-11-01 2006-03-07 Research Foundation Of The State University Of New York Recombinant constructs of Borrelia burgdorferi
ZA964896B (en) * 1995-06-07 1997-01-08 Connaught Lab Expression of lipoproteins
NZ525674A (en) * 1998-02-03 2005-01-28 Ct Disease Contr & Prevention Recombinant lipidated PsaA protein, methods of preparation and use
AU2003204215B2 (en) * 1998-02-03 2007-01-11 Aventis Pasteur Recombinant Lipidated PsaA Protein, Methods of Preparation and Use
PT2270030E (pt) * 2000-02-28 2012-07-24 Novartis Vaccines & Diagnostic Expressão heteróloga de proteínas de neisseria
EP1311540B1 (de) 2000-08-18 2007-12-19 Research Foundation Of State University Of New York Veränderte borrelia burgdorferi ospa
MY144532A (en) 2001-08-20 2011-09-30 Lundbeck & Co As H Novel method for down-regulation of amyloid
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
JP5024830B2 (ja) 2004-10-25 2012-09-12 ステーテンズ セーラム インスティテュート クラミジア・トラコマチス（Ｃｈｌａｍｙｄｉａｔｒａｃｈｏｍａｔｉｓ）抗原のワクチンおよび診断への使用
US7968105B2 (en) 2005-06-23 2011-06-28 Statens Serum Institut Tuberculosis vaccines comprising antigens expressed during the latent infection phase
AU2007205838A1 (en) 2006-01-19 2007-07-26 Mary Kay, Inc. Compositions comprising kakadu plum extract or acai berry extract
US20090324638A1 (en) * 2006-06-12 2009-12-31 Biopeptides Corp. Live bacterial vaccine
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
EP2199303B1 (de) 2008-12-12 2013-06-05 Euroimmun Medizinische Labordiagnostika AG Polypeptide und Verfahren zur spezifischen Detektion von Antikörpern bei Patienten mit einer Borrelieninfektion
EP2421557B1 (de) 2009-04-24 2018-12-05 Statens Serum Institut Tuberkulose-tb-impstoff zur reaktivierungsverhinderung
MX2012002424A (es) 2009-08-28 2012-06-27 Mary Kay Inc Formulaciones para el cuidado de la piel.
CA2808975C (en) 2010-08-23 2018-10-30 Wyeth Llc Stable formulations of neisseria meningitidis rlp2086 antigens
KR101584871B1 (ko) 2010-09-10 2016-01-22 와이어쓰 엘엘씨 네이세리아 메닝기티디스 orf2086 항원의 비-지질화된 변이체
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
CA2865745C (en) 2012-03-09 2018-01-09 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
CA2903716C (en) 2013-03-08 2019-04-09 Pfizer Inc. Immunogenic fusion polypeptides
RU2662968C2 (ru) 2013-09-08 2018-07-31 Пфайзер Инк. Иммуногенная композиция против neisseria meningitidis (варианты)
KR20190049940A (ko) 2015-02-19 2019-05-09 화이자 인코포레이티드 나이세리아 메닌지티디스 조성물 및 그의 방법
SG11201906519RA (en) 2017-01-31 2019-08-27 Pfizer Neisseria meningitidis compositions and methods thereof
CA3155669A1 (en) 2019-09-27 2021-04-01 Pfizer Inc. Neisseria meningitidis compositions and methods thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4624926A (en) * 1981-01-02 1986-11-25 The Research Foundation Of State University Of New York Novel cloning vehicles for polypeptide expression in microbial hosts
CA2032914A1 (en) * 1989-12-26 1991-06-27 Peter C.K. Lau Use of bacterial lipoprotein amino terminus in fusion plasmids for in vivo expression of lipid modified polypeptides
SG122738A1 (en) * 1990-06-15 2006-06-29 Univ Yale Compositions and methods for the prevention and diagnosis of lyme disease
FI933580L (fi) * 1991-02-15 1993-10-13 Uab Research Foundation Strukturgen av pneumokockprotein
ES2194010T3 (es) * 1991-10-22 2003-11-16 Symbicom Ab Mejoras en el diagnostico y profilaxis de la borrelia burgdorferi.
WO1994014318A1 (en) * 1992-12-24 1994-07-07 Medimmune, Inc. Method of protection against streptococcus pneumoniae with transformed mycobacteria

Also Published As

Publication number Publication date
ES2271954T3 (es) 2007-04-16
EP0832093A1 (de) 1998-04-01
CA2223300A1 (en) 1996-12-19
EP1741718A2 (de) 2007-01-10
ATE339436T1 (de) 2006-10-15
CA2223300C (en) 2010-07-27
EP1741718A3 (de) 2007-03-28
DE69636544T2 (de) 2007-06-06
IL118578A0 (en) 1996-10-16
PT832093E (pt) 2006-12-29
EP0832093A4 (de) 2001-01-03
AU6134396A (en) 1996-12-30
WO1996040718A1 (en) 1996-12-19
FI974422A7 (fi) 1998-02-04
FI974422L (fi) 1998-02-04
EP0832093B1 (de) 2006-09-13
AU721954B2 (en) 2000-07-20
NO20064621L (no) 1998-01-30
CA2704354A1 (en) 1996-12-19
JPH11514841A (ja) 1999-12-21
DE69636544D1 (de) 2006-10-26
NO975619L (no) 1998-01-30
IL118578A (en) 2006-12-31
NO975619D0 (no) 1997-12-04
JP4091112B2 (ja) 2008-05-28
FI974422A0 (fi) 1997-12-05
DK0832093T3 (da) 2007-01-08

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