NO324323B1 - Nytt salt av perindopril og farmasoytiske sammensetninger inneholdende det - Google Patents

Nytt salt av perindopril og farmasoytiske sammensetninger inneholdende det Download PDF

Info

Publication number
NO324323B1
NO324323B1 NO20030849A NO20030849A NO324323B1 NO 324323 B1 NO324323 B1 NO 324323B1 NO 20030849 A NO20030849 A NO 20030849A NO 20030849 A NO20030849 A NO 20030849A NO 324323 B1 NO324323 B1 NO 324323B1
Authority
NO
Norway
Prior art keywords
perindopril
salt
pharmaceutical compositions
compositions containing
tert
Prior art date
Application number
NO20030849A
Other languages
English (en)
Norwegian (no)
Other versions
NO20030849L (no
NO20030849D0 (no
Inventor
Francois Lefoulon
Gerard Damien
Bernard Marchand
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8871521&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO324323(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Servier Lab filed Critical Servier Lab
Publication of NO20030849D0 publication Critical patent/NO20030849D0/no
Publication of NO20030849L publication Critical patent/NO20030849L/no
Publication of NO324323B1 publication Critical patent/NO324323B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Peptides Or Proteins (AREA)
NO20030849A 2002-04-18 2003-02-24 Nytt salt av perindopril og farmasoytiske sammensetninger inneholdende det NO324323B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0204847A FR2838648B1 (fr) 2002-04-18 2002-04-18 Nouveau sel de perindopril et les compositions pharmaceutiques qui le contiennent

Publications (3)

Publication Number Publication Date
NO20030849D0 NO20030849D0 (no) 2003-02-24
NO20030849L NO20030849L (no) 2003-10-20
NO324323B1 true NO324323B1 (no) 2007-09-24

Family

ID=8871521

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20030849A NO324323B1 (no) 2002-04-18 2003-02-24 Nytt salt av perindopril og farmasoytiske sammensetninger inneholdende det

Country Status (37)

Country Link
US (1) US6696481B2 (sr)
EP (1) EP1354873B1 (sr)
JP (1) JP3737488B2 (sr)
KR (1) KR100542468B1 (sr)
CN (1) CN1211365C (sr)
AP (1) AP1787A (sr)
AR (1) AR039428A1 (sr)
AT (1) ATE271036T1 (sr)
AU (2) AU2003222921A1 (sr)
BR (1) BR0300709A (sr)
CA (1) CA2423825C (sr)
CR (1) CR7576A (sr)
DE (1) DE60300011T2 (sr)
DK (1) DK1354873T3 (sr)
EA (1) EA005676B1 (sr)
EC (1) ECSP045441A (sr)
ES (1) ES2224092T3 (sr)
FR (1) FR2838648B1 (sr)
GE (1) GEP20074211B (sr)
HR (1) HRP20041079B1 (sr)
IL (1) IL164424A (sr)
IS (1) IS2842B (sr)
MA (1) MA27115A1 (sr)
ME (1) ME00454B (sr)
MX (1) MXPA03002346A (sr)
NO (1) NO324323B1 (sr)
NZ (1) NZ524478A (sr)
OA (1) OA12806A (sr)
PL (1) PL359321A1 (sr)
PT (1) PT1354873E (sr)
RS (1) RS51694B (sr)
SI (1) SI1354873T1 (sr)
TN (1) TNSN04206A1 (sr)
TR (1) TR200401793T4 (sr)
UA (1) UA79463C2 (sr)
WO (1) WO2003087050A2 (sr)
ZA (1) ZA200301395B (sr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2395195A (en) * 2002-11-18 2004-05-19 Cipla Ltd Preparation of perindopril from carboxy-protected precursor, & perindopril monohydrates for use as angiotensin converting enzyme (ACE) inhibitors
PT1729739T (pt) 2004-03-29 2016-12-01 Servier Lab Processo para a preparação de uma composição farmacêutica sólida
SI21800A (sl) 2004-05-14 2005-12-31 Krka, Tovarna Zdravil, D.D., Novo Mesto Nov postopek sinteze perindoprila
PT1679072E (pt) * 2005-01-06 2008-12-22 Ipca Lab Ltd Processo para a síntese de derivados de ácido (2s,3as,7as)-1-(s)-alanil-octa-hidro-1h-indole-2-carboxílico e utilização na síntese de perindopril
DK1861367T3 (da) * 2005-03-14 2009-11-02 Servier Lab Forbedret fremgangsmåde til oprensning af perindopril
FR2894825B1 (fr) * 2005-12-21 2010-12-03 Servier Lab Nouvelle association d'un inhibiteur du courant if sinusal et d'un inhibiteur de l'enzyme de conversion et les compositions pharmaceutiques qui la contiennent
FR2897866B1 (fr) 2006-02-28 2008-04-18 Servier Lab Forme cristalline alpha du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2897865B1 (fr) * 2006-02-28 2008-04-18 Servier Lab Forme cristalline beta du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
GB0624084D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril amino acid salts
GB0624087D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril combination salt
GB0624090D0 (en) * 2006-12-01 2007-01-10 Selamine Ltd Ramipril amine salts
SI22542A (sl) * 2007-06-04 2008-12-31 Diagen D.O.O. Stabilna formulacija amorfnih soli perindoprila, postopek za njeno pripravo v industrijskem merilu in njena uporaba za zdravljenje hipertenzije
US8686161B2 (en) * 2008-06-24 2014-04-01 Mylan Laboratories Limited Polymorphic forms of perindopril (L)-arginine and process for the preparation thereof
AU2009212902A1 (en) * 2008-09-03 2010-03-18 Apotex Pharmachem Inc. Amorphous form of an L-arginine salt of perindopril and processes of preparation thereof
CN101766598A (zh) * 2008-12-31 2010-07-07 东英（江苏）药业有限公司 含有培哚普利的药物组合物
GB0910692D0 (en) 2009-06-20 2009-08-05 Teva Pharma Compound
SI23149A (sl) 2009-09-21 2011-03-31 Silverstone Pharma Nove benzatinske soli ACE inhibitorjev, postopek za njihovo pripravo in njihova uporaba za zdravljenje kardiovaskularnih bolezni
FR2961105B1 (fr) * 2010-06-15 2013-02-08 Servier Lab Utilisation de l'association d'un inhibiteur du courant if sinusal et d'un inhibiteur de l'enzyme de conversion de l'angiotensine pour le traitement de l'insuffisance cardiaque
FR2985511B1 (fr) 2012-01-05 2014-01-03 Servier Lab Forme cristalline delta du sel d'arginine du perindopril, son procede de preparation, et les compositions pharmaceutiques qui la contiennent
FR2985512B1 (fr) * 2012-01-05 2014-06-20 Servier Lab Procede de preparation du sel de l-arginine du perindopril
CN103172696B (zh) * 2012-12-19 2014-12-17 宁波美诺华药业股份有限公司 一种γ晶型的培哚普利精氨酸盐的制备方法
FR3040303B1 (fr) * 2015-08-27 2019-04-05 Les Laboratoires Servier Suivi Par Sabine Goudeau-Wenger Composition pharmaceutique comprenant un inhibiteur de la hmg-coa reductase et un inhibiteur eca
PH12018502155B1 (en) 2016-04-20 2024-03-27 Servier Lab Pharmaceutical composition comprising a beta blocker, a converting enzyme inhibitor and an antihypertensive or an nsaid
EP3842035A1 (en) 2019-12-23 2021-06-30 KRKA, d.d., Novo mesto Composition for the preparation of perindopril arginine granules, a method for their preparation and pharmaceutical composition comprising the granules
SI26268A (sl) 2021-11-18 2023-05-31 Zupet Rok Postopek za pripravo hidratirane oblike perindopril l-arginina

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2503155A2 (fr) * 1980-10-02 1982-10-08 Science Union & Cie Nouveaux imino diacides substitues, leurs procedes de preparation et leur emploi comme inhibiteur d'enzyme
FR2811320B1 (fr) * 2000-07-06 2002-08-23 Adir Nouvelle forme cristalline alpha du sel de tert-butylamine du perindopril, son procede de preparation et les compositions pharmaceutiques qui la contiennent

Also Published As

Publication number Publication date
NO20030849L (no) 2003-10-20
CA2423825A1 (fr) 2003-10-18
PL359321A1 (en) 2003-10-20
ME00454B (me) 2011-10-10
AU2003222921A8 (en) 2003-10-27
AU2003200700C1 (en) 2015-04-23
CA2423825C (fr) 2006-02-21
FR2838648B1 (fr) 2004-05-21
JP2003321493A (ja) 2003-11-11
SI1354873T1 (en) 2004-12-31
HRP20041079B1 (hr) 2013-04-30
UA79463C2 (en) 2007-06-25
US6696481B2 (en) 2004-02-24
ES2224092T3 (es) 2005-03-01
PT1354873E (pt) 2004-10-29
IL164424A0 (en) 2005-12-18
DE60300011D1 (de) 2004-08-19
AU2003200700A1 (en) 2003-11-06
KR100542468B1 (ko) 2006-01-11
AP2004003154A0 (en) 2004-12-31
KR20030082902A (ko) 2003-10-23
ATE271036T1 (de) 2004-07-15
AU2003200700B2 (en) 2005-01-20
WO2003087050A2 (fr) 2003-10-23
CN1211365C (zh) 2005-07-20
TNSN04206A1 (en) 2007-03-12
OA12806A (en) 2006-07-11
ZA200301395B (en) 2003-09-02
US20030199568A1 (en) 2003-10-23
CR7576A (es) 2008-08-21
EA005676B1 (ru) 2005-04-28
AU2003222921A1 (en) 2003-10-27
IL164424A (en) 2010-12-30
GEP20074211B (en) 2007-10-10
IS2842B (is) 2013-08-15
WO2003087050A3 (fr) 2004-03-25
MA27115A1 (fr) 2004-12-20
EA200300334A1 (ru) 2003-12-25
RS51694B (sr) 2011-10-31
CN1451656A (zh) 2003-10-29
NO20030849D0 (no) 2003-02-24
HRP20041079A2 (en) 2004-12-31
ECSP045441A (es) 2005-03-10
AP1787A (en) 2007-10-04
TR200401793T4 (tr) 2004-08-23
FR2838648A1 (fr) 2003-10-24
EP1354873A1 (fr) 2003-10-22
AR039428A1 (es) 2005-02-16
IS7516A (is) 2004-10-27
RS90904A (sr) 2007-02-05
MXPA03002346A (es) 2005-08-26
DK1354873T3 (da) 2004-11-01
NZ524478A (en) 2004-05-28
BR0300709A (pt) 2004-09-08
HK1057367A1 (en) 2004-04-02
DE60300011T2 (de) 2005-03-17
EP1354873B1 (fr) 2004-07-14
JP3737488B2 (ja) 2006-01-18

Similar Documents

Publication Publication Date Title
US6696481B2 (en) Salt of perindopril and pharmaceutical compositions containing it
Agianian et al. Structure of a Drosophila sigma class glutathione S-transferase reveals a novel active site topography suited for lipid peroxidation products
Schuetz et al. Human HDAC7 harbors a class IIa histone deacetylase-specific zinc binding motif and cryptic deacetylase activity
CA2400155C (en) A novel crystalline form of n-[4-[2-(2-amino-4,7-dihydro-4-oxo-3h-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-l-glutamic acid and process therefor
JP5665538B2 (ja) （１ｓ，２ｓ，３ｓ，４ｒ）−３−［（１ｓ）−１−アセチルアミノ−２−エチル−ブチル］−４−グアニジノ−２−ヒドロキシ−シクロペンチル−１−カルボン酸水和物及びその使用
ES2910003T3 (es) Compuestos y composiciones de cocristal iónico de litio de anión orgánico
CN101778855A (zh) 替诺福韦酯半富马酸共晶体
NO308999B1 (no) Nye, kjemiske forbindelser, og farmasøytisk preparat inneholdende disse
PT2225261E (pt) Inibidores boropeptídicos de enteropeptidase e suas utilizações no tratamento de obesidade, excesso de peso e/ou doenças associadas com um metabolismo anormal da gordura
MX2007010532A (es) Derivados de amida de acido 1-sulfonil-piperidina-3-carboxilico como inhibidores de 11-beta-hidroxiesteroide deshidrogenasa para el tratamiento de diabetes mellitus tipo ii.
SG190667A1 (en) 5-lipoxygenase-activating protein inhibitor
ES2339935T3 (es) Nuevas sales de atorvastatina y composiciones farmaceuticas que las contienen.
Brangulis et al. Structural and functional analysis of BB0689 from Borrelia burgdorferi, a member of the bacterial CAP superfamily
KR20170084107A (ko) 레바프라잔 염산염 다형체 및 그의 제조 방법
ES2387435B1 (es) Uso de heptapéptidos para el control de la hipertensión
WO2010111951A1 (zh) 普拉格雷氢溴酸盐的晶体
WO2019173159A1 (en) Ergothioneine compositions and methods for maintaining and/or increasing vitamin c levels in cells and organisms
CN103893131B (zh) 一种含有非布司他的固体药物组合物
US12611417B1 (en) Compositions and methods to inhibit acid-catalyzed dephosphorylation of phosphoryloxytryptamines
Gibson et al. Sickle cell disease and 5HMF: the search for effective treatments
US12497637B1 (en) Stabilization of tryptamines by denaturing enzymes, optimizing ionization states, and controlling confounding variables
US12503713B1 (en) Stabilization of tryptamines by denaturing enzymes, optimizing ionization states, and controlling confounding variables
HK1057367B (en) New salt of perindopril and pharmaceutical compositions containing it
WO2017098514A1 (en) Nupharidine compounds and derivatives thereof for the treatment of cysteine protease related diseases

Legal Events

Date Code Title Description
MK1K Patent expired