NO327317B1 - Vektor for fremstillingen av IL-4 og IL-4-mutanter, DNA-konstruksjon og E.coli. - Google Patents

Vektor for fremstillingen av IL-4 og IL-4-mutanter, DNA-konstruksjon og E.coli. Download PDF

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Publication number
NO327317B1
NO327317B1 NO20000262A NO20000262A NO327317B1 NO 327317 B1 NO327317 B1 NO 327317B1 NO 20000262 A NO20000262 A NO 20000262A NO 20000262 A NO20000262 A NO 20000262A NO 327317 B1 NO327317 B1 NO 327317B1
Authority
NO
Norway
Prior art keywords
vector
gene
expression
mutants
plasmid
Prior art date
Application number
NO20000262A
Other languages
English (en)
Norwegian (no)
Other versions
NO20000262D0 (no
NO20000262L (no
Inventor
Heiner Apeler
Hermann Wehlmann
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Publication of NO20000262D0 publication Critical patent/NO20000262D0/no
Publication of NO20000262L publication Critical patent/NO20000262L/no
Publication of NO327317B1 publication Critical patent/NO327317B1/no

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/5406IL-4
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • C12N15/72Expression systems using regulatory sequences derived from the lac-operon

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO20000262A 1999-01-20 2000-01-19 Vektor for fremstillingen av IL-4 og IL-4-mutanter, DNA-konstruksjon og E.coli. NO327317B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99100967A EP1022339B1 (en) 1999-01-20 1999-01-20 Plasmids, their construction and their use in the manufacture of interleukin-4 and interleukin-4 muteins

Publications (3)

Publication Number Publication Date
NO20000262D0 NO20000262D0 (no) 2000-01-19
NO20000262L NO20000262L (no) 2000-07-21
NO327317B1 true NO327317B1 (no) 2009-06-08

Family

ID=8237378

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20000262A NO327317B1 (no) 1999-01-20 2000-01-19 Vektor for fremstillingen av IL-4 og IL-4-mutanter, DNA-konstruksjon og E.coli.

Country Status (15)

Country Link
US (1) US6506590B1 (cs)
EP (1) EP1022339B1 (cs)
JP (2) JP2000210091A (cs)
KR (1) KR100665148B1 (cs)
AT (1) ATE334202T1 (cs)
AU (1) AU772897B2 (cs)
CA (1) CA2294575C (cs)
CZ (1) CZ294279B6 (cs)
DE (1) DE69929638T2 (cs)
DK (1) DK1022337T3 (cs)
ES (1) ES2269027T3 (cs)
HU (1) HU224491B1 (cs)
NO (1) NO327317B1 (cs)
PT (1) PT1022337E (cs)
SK (1) SK285603B6 (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10022258A1 (de) 2000-05-08 2001-11-15 Bayer Ag Reinigung von Proteineinschlusskörpern durch Querstrom-Mikrofiltration
KR100443570B1 (ko) * 2001-07-31 2004-08-09 크레아젠 주식회사 재조합 인간 인터루킨-4의 제조방법
EP1314739A1 (en) 2001-11-22 2003-05-28 Bayer Ag Process for renaturation of recombinant, disulfide containing proteins at high protein concentrations in the presence of amines
JP2006055082A (ja) * 2004-08-20 2006-03-02 National Institute Of Advanced Industrial & Technology 発光甲虫由来赤色発光酵素安定体の生産及び精製法
CN118440969B (zh) * 2024-07-08 2024-10-15 天津凯莱英生物科技有限公司 可溶性表达质粒突变体库的构建方法及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4689406A (en) * 1983-08-10 1987-08-25 Amgen Enhancement of microbial expression of polypeptides
EP0241446B1 (en) * 1986-03-27 1995-03-01 Monsanto Company Enhanced protein production in bacteria by employing a novel ribosome binding site
DK443288A (da) * 1987-08-17 1989-02-18 Hoffmann La Roche Ekspressionskontrolsekvenser
FR2724665B1 (fr) * 1994-09-16 1996-12-20 Rhone Poulenc Rorer Sa Procede de production de proteines recombinantes, plasmides et cellules modifiees
MY124565A (en) * 1996-07-19 2006-06-30 Bayer Corp High-affinity interleukin-4-muteins

Also Published As

Publication number Publication date
NO20000262D0 (no) 2000-01-19
CA2294575A1 (en) 2000-07-20
DE69929638D1 (de) 2006-04-13
SK762000A3 (en) 2000-08-14
JP2010284174A (ja) 2010-12-24
US6506590B1 (en) 2003-01-14
CA2294575C (en) 2009-04-07
KR100665148B1 (ko) 2007-01-09
CZ2000214A3 (cs) 2000-08-16
ES2269027T3 (es) 2007-04-01
CZ294279B6 (cs) 2004-11-10
NO20000262L (no) 2000-07-21
HUP0000185A2 (en) 2002-09-28
AU772897B2 (en) 2004-05-13
HU224491B1 (hu) 2005-09-28
KR20000053523A (ko) 2000-08-25
PT1022337E (pt) 2006-11-30
SK285603B6 (sk) 2007-04-05
HU0000185D0 (en) 2000-04-28
AU1250700A (en) 2000-07-27
EP1022339B1 (en) 2006-02-01
DK1022337T3 (da) 2006-11-06
DE69929638T2 (de) 2006-09-21
ATE334202T1 (de) 2006-08-15
EP1022339A1 (en) 2000-07-26
JP2000210091A (ja) 2000-08-02

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