NO328507B1 - Tumorassosierte antigenderivater fra MAGE-familien, vaksine inneholdende slike og anvendelse for fremstilling av vaksine, samt fremgangsmate for rensing av antigenderivatene og fremstilling av vaksinen - Google Patents

Tumorassosierte antigenderivater fra MAGE-familien, vaksine inneholdende slike og anvendelse for fremstilling av vaksine, samt fremgangsmate for rensing av antigenderivatene og fremstilling av vaksinen Download PDF

Info

Publication number: NO328507B1
Authority: NO; Norway
Prior art keywords: mage; protein; vaccine; antigen; lpd
Prior art date: 1998-02-05

Application number

NO20003958A

Other languages

English (en)

Norwegian (no)

Other versions

NO20003958L (no

NO20003958D0 (no

Inventor

Silva Teresa Cabezon

Joseph Cohen

Moncef Mohamed Slaoui

Bassols Carlota Vinals

Original Assignee

Glaxosmithkline Biolog Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-02-05

Filing date

2000-08-04

Publication date

2010-03-08

1998-02-05 Priority claimed from GBGB9802543.0A external-priority patent/GB9802543D0/en

1998-02-06 Priority claimed from GBGB9802650.3A external-priority patent/GB9802650D0/en

2000-08-04 Application filed by Glaxosmithkline Biolog Sa filed Critical Glaxosmithkline Biolog Sa

2000-08-04 Publication of NO20003958D0 publication Critical patent/NO20003958D0/no

2000-10-04 Publication of NO20003958L publication Critical patent/NO20003958L/no

2010-03-08 Publication of NO328507B1 publication Critical patent/NO328507B1/no

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001184—Cancer testis antigens, e.g. SSX, BAGE, GAGE or SAGE
- A61K39/001186—MAGE
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Immunology (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Zoology (AREA)
Mycology (AREA)
Oncology (AREA)
Microbiology (AREA)
Communicable Diseases (AREA)
Marine Sciences & Fisheries (AREA)
Toxicology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicinal Preparation (AREA)

NO20003958A 1998-02-05 2000-08-04 Tumorassosierte antigenderivater fra MAGE-familien, vaksine inneholdende slike og anvendelse for fremstilling av vaksine, samt fremgangsmate for rensing av antigenderivatene og fremstilling av vaksinen NO328507B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9802543.0A GB9802543D0 (en)	1998-02-05	1998-02-05	Vaccine
GBGB9802650.3A GB9802650D0 (en)	1998-02-06	1998-02-06	Vaccine
PCT/EP1999/000660 WO1999040188A2 (en)	1998-02-05	1999-02-02	Tumor-associated antigen derivatives from the mage family, and nucleic acid sequences encoding them, used for the preparation of fusion proteins and of compositions for vaccinations

Publications (3)

Publication Number	Publication Date
NO20003958D0 NO20003958D0 (no)	2000-08-04
NO20003958L NO20003958L (no)	2000-10-04
NO328507B1 true NO328507B1 (no)	2010-03-08

Family

ID=26313069

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO20003958A NO328507B1 (no)	1998-02-05	2000-08-04	Tumorassosierte antigenderivater fra MAGE-familien, vaksine inneholdende slike og anvendelse for fremstilling av vaksine, samt fremgangsmate for rensing av antigenderivatene og fremstilling av vaksinen
NO20091665A NO331719B1 (no)	1998-02-05	2009-04-27	Fremgangsmate for rensing eller fremstilling av et MAGE protein samt fremstilling av en vaksine

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO20091665A NO331719B1 (no)	1998-02-05	2009-04-27	Fremgangsmate for rensing eller fremstilling av et MAGE protein samt fremstilling av en vaksine

Country Status (25)

Country	Link
US (3)	US8097257B2 (cs)
EP (4)	EP1584685B1 (cs)
JP (2)	JP4768121B2 (cs)
KR (2)	KR100824105B1 (cs)
CN (1)	CN1227360C (cs)
AR (1)	AR018064A1 (cs)
AT (4)	ATE505542T1 (cs)
AU (1)	AU737337B2 (cs)
BR (1)	BR9907691B1 (cs)
CA (2)	CA2584482C (cs)
CY (4)	CY1105685T1 (cs)
CZ (2)	CZ298364B6 (cs)
DE (3)	DE69929310T2 (cs)
DK (4)	DK1659178T3 (cs)
ES (2)	ES2342416T3 (cs)
HU (1)	HU228467B1 (cs)
IL (4)	IL137442A0 (cs)
NO (2)	NO328507B1 (cs)
NZ (1)	NZ506086A (cs)
PT (4)	PT1053325E (cs)
SA (1)	SA99200126B1 (cs)
SI (4)	SI1053325T1 (cs)
TR (1)	TR200002284T2 (cs)
TW (1)	TWI238853B (cs)
WO (1)	WO1999040188A2 (cs)

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Publication number	Publication date
EP1659178B1 (en)	2010-03-31
IL188875A0 (en)	2009-02-11
DE69942214D1 (de)	2010-05-12
ATE513042T1 (de)	2011-07-15
CY1111831T1 (el)	2015-10-07
ES2255248T3 (es)	2006-06-16
KR100633212B1 (ko)	2006-10-11
CN1227360C (zh)	2005-11-16
CN1295616A (zh)	2001-05-16
CY1110180T1 (el)	2015-01-14
DE69929310T2 (de)	2006-08-03
HK1093521A1 (en)	2007-03-02
KR20060067977A (ko)	2006-06-20
PT1584685E (pt)	2011-06-17
EP1659179A2 (en)	2006-05-24
PT1053325E (pt)	2006-05-31
EP1584685A3 (en)	2005-12-07
CA2584482C (en)	2012-03-27
NO331719B1 (no)	2012-03-05
JP2002502604A (ja)	2002-01-29
TR200002284T2 (tr)	2000-11-21
SI1584685T1 (sl)	2011-07-29
BR9907691B1 (pt)	2011-05-31
EP1659178A2 (en)	2006-05-24
AU2722099A (en)	1999-08-23
EP1053325B1 (en)	2006-01-04
IL179010A0 (en)	2007-03-08
EP1584685A2 (en)	2005-10-12
EP1659179A3 (en)	2007-01-17
DE69929310D1 (de)	2006-03-30
ATE315088T1 (de)	2006-02-15
SI1053325T1 (sl)	2006-06-30
WO1999040188A2 (en)	1999-08-12
NO20091665L (no)	2000-10-04
JP2009201510A (ja)	2009-09-10
CZ20002869A3 (cs)	2001-01-17
ES2342416T3 (es)	2010-07-06
NO20003958L (no)	2000-10-04
IL137442A0 (en)	2001-07-24
US20120269835A1 (en)	2012-10-25
US20100209444A1 (en)	2010-08-19
US8097257B2 (en)	2012-01-17
JP4768121B2 (ja)	2011-09-07
EP1659179B1 (en)	2011-06-15
EP1659178A3 (en)	2007-01-17
DK1659178T3 (da)	2010-07-12
US20100204458A1 (en)	2010-08-12
PT1659178E (pt)	2010-06-28
NZ506086A (en)	2003-01-31
PT1659179E (pt)	2011-09-16
WO1999040188A3 (en)	1999-10-14
CA2584482A1 (en)	1999-08-12
KR20010040675A (ko)	2001-05-15
CZ298364B6 (cs)	2007-09-05
HUP0102639A3 (en)	2004-04-28
DK1659179T3 (da)	2011-10-10
CY1111672T1 (el)	2015-10-07
ATE462788T1 (de)	2010-04-15
EP1584685B1 (en)	2011-04-13
EP1053325A2 (en)	2000-11-22
IL137442A (en)	2008-04-13
ATE505542T1 (de)	2011-04-15
HK1033838A1 (en)	2001-09-28
SI1659178T1 (sl)	2010-07-30
AU737337B2 (en)	2001-08-16
SA99200126B1 (ar)	2006-08-20
CY1105685T1 (el)	2010-12-22
HU228467B1 (en)	2013-03-28
HK1083026A1 (en)	2006-06-23
IL188875A (en)	2011-08-31
HK1093522A1 (en)	2007-03-02
BR9907691A (pt)	2000-11-14
DE69943359D1 (de)	2011-05-26
AR018064A1 (es)	2001-10-31
CA2319309A1 (en)	1999-08-12
DK1584685T3 (da)	2011-07-11
SI1659179T1 (sl)	2011-10-28
DK1053325T3 (da)	2006-05-22
KR100824105B1 (ko)	2008-04-21
CA2319309C (en)	2010-08-10
NO20003958D0 (no)	2000-08-04
US8044183B2 (en)	2011-10-25
HUP0102639A1 (hu)	2001-11-28
CZ298347B6 (cs)	2007-09-05
US8597656B2 (en)	2013-12-03
TWI238853B (en)	2005-09-01
PL342852A1 (en)	2001-07-16

Legal Events

Date	Code	Title	Description
2015-09-28	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
NO328507B1 (no)	2010-03-08	Tumorassosierte antigenderivater fra MAGE-familien, vaksine inneholdende slike og anvendelse for fremstilling av vaksine, samt fremgangsmate for rensing av antigenderivatene og fremstilling av vaksinen
ES2367998T3 (es)	2011-11-11	Derivados antígenos asociados a tumores de la familia mage, y secuencias de ácidos nucleicos que los codifican, usados para la preparación de proteínas de fusión y de composiciones para vacunación.
HK1093522B (en)	2010-09-17	A process for the purification or production of a mage protein
HK1083026B (en)	2011-12-09	Tumor-associated antigen derivatives from the mage family, used for the preparation of fusion proteins with t-helper epitopes and of compositions for vaccination
HK1093521B (en)	2011-12-09	Tumor-associated antigen derivatives from the mage family, and nucleic acid sequences encoding them, used for the preparation of fusion proteins and of compositions for vaccination
PL203645B1 (pl)	2009-10-30	Pochodna antygenu zwi azanego z nowotworem z rodziny MAGE i jej zastosowanie, sekwencja kwasu nukleinowego i jego zastosowanie, wektor, komórka gospodarza, szczepionka, sposób oczyszczania bia lka MAGE albo jego pochodnej, oraz sposób wytwarzania szczepionki
PL203658B1 (pl)	2009-10-30	Bia lko fuzyjne zawieraj ace antygen kodowany przez rodzin e genów MAGE oraz jego zastosowanie, sekwencja kwasu nukleinowego i jego zastosowanie, wektor, komórka gospodarza i szczepionka
HK1033838B (en)	2006-11-03	Tumor-associated antigen derivatives from the mage family, and nucleic acid sequences encoding them, used for the preparation of fusion proteins and of compositions for vaccination
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