NO333505B1 - 4,4-difluor-1,2,3,4-tetrahydro-5H-1-benzazepinderivat eller salt derav, og anvendelse derav for fremstilling av et medikament - Google Patents

4,4-difluor-1,2,3,4-tetrahydro-5H-1-benzazepinderivat eller salt derav, og anvendelse derav for fremstilling av et medikament Download PDF

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Publication number
NO333505B1
NO333505B1 NO20055602A NO20055602A NO333505B1 NO 333505 B1 NO333505 B1 NO 333505B1 NO 20055602 A NO20055602 A NO 20055602A NO 20055602 A NO20055602 A NO 20055602A NO 333505 B1 NO333505 B1 NO 333505B1
Authority
NO
Norway
Prior art keywords
tetrahydro
trifluoromethyl
compound
ylidene
benzoyl
Prior art date
Application number
NO20055602A
Other languages
English (en)
Norwegian (no)
Other versions
NO20055602D0 (no
NO20055602L (no
Inventor
Hiroyuki Koshio
Issei Tsukamoto
Akio Kakefuda
Seijiro Akamatsu
Chikashi Saitoh
Original Assignee
Astellas Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astellas Pharma Inc filed Critical Astellas Pharma Inc
Publication of NO20055602D0 publication Critical patent/NO20055602D0/no
Publication of NO20055602L publication Critical patent/NO20055602L/no
Publication of NO333505B1 publication Critical patent/NO333505B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO20055602A 2003-04-28 2005-11-25 4,4-difluor-1,2,3,4-tetrahydro-5H-1-benzazepinderivat eller salt derav, og anvendelse derav for fremstilling av et medikament NO333505B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2003123032 2003-04-28
JP2003401126 2003-12-01
PCT/JP2004/005998 WO2004096775A1 (ja) 2003-04-28 2004-04-26 4,4-ジフルオロ-1,2,3,4-テトラヒドロ-5h-1-ベンゾアゼピン誘導体又はその塩

Publications (3)

Publication Number Publication Date
NO20055602D0 NO20055602D0 (no) 2005-11-25
NO20055602L NO20055602L (no) 2006-01-24
NO333505B1 true NO333505B1 (no) 2013-06-24

Family

ID=33422056

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20055602A NO333505B1 (no) 2003-04-28 2005-11-25 4,4-difluor-1,2,3,4-tetrahydro-5H-1-benzazepinderivat eller salt derav, og anvendelse derav for fremstilling av et medikament

Country Status (17)

Country Link
US (2) US7183271B2 (de)
EP (1) EP1619185B1 (de)
KR (1) KR100882154B1 (de)
AT (1) ATE512951T1 (de)
AU (1) AU2004234258B2 (de)
BR (1) BRPI0409718A (de)
CA (1) CA2521492C (de)
DK (1) DK1619185T3 (de)
IL (1) IL171332A (de)
MX (1) MXPA05011521A (de)
NO (1) NO333505B1 (de)
NZ (1) NZ542815A (de)
PL (1) PL1619185T3 (de)
PT (1) PT1619185E (de)
RU (1) RU2326868C2 (de)
SI (1) SI1619185T1 (de)
WO (1) WO2004096775A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0210397D0 (en) 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
SI1619185T1 (sl) 2003-04-28 2011-09-30 Astellas Pharma Inc 4,4-difluoro-1,2,3,4-tetrahidro-5H-1-benzazepinski derivat ali njegova sol
NZ565080A (en) 2005-07-22 2011-03-31 Mochida Pharm Co Ltd Novel heterocyclidene acetamide derivative
AU2008283929B2 (en) 2007-08-06 2013-10-10 Serenity Pharmaceuticals, Llc Methods and devices for desmopressin drug delivery
PL2712622T3 (pl) * 2008-05-21 2017-01-31 Ferring B.V. Ulegająca rozpadowi w ustach desmopresyna do zwiększania początkowego okresu snu niezakłócanego przez nokturię
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
DK2860175T3 (da) * 2012-06-11 2018-01-29 Tacurion Fremgangsmåde til fremstilling af 4,4,7-trifluor-1,2,3,4-tetrahydro-5h-1-benzazepin-forbindelse og intermediat til syntese deraf
WO2018011681A1 (en) 2016-07-14 2018-01-18 Pfizer Inc. Novel pyrimidine carboxamides as inhibitors of vanin-1 enzyme

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2137760C1 (ru) * 1993-08-26 1999-09-20 Яманоути Фармасьютикал Ко., Лтд. Производное бензазепина, фармацевтическая композиция, производное дифторбензазепина и производное (замещенного) аминобензоилдифторбензазепина
JP3215910B2 (ja) 1994-06-15 2001-10-09 大塚製薬株式会社 ベンゾヘテロ環誘導体
JPH11349570A (ja) 1994-06-15 1999-12-21 Otsuka Pharmaceut Co Ltd ベンゾヘテロ環誘導体
ES2284741T3 (es) 1994-06-15 2007-11-16 Otsuka Pharmaceutical Company, Limited Derivados de benzoheterociclicos utilizados como moduladores de vasoprsinao de oxitocina.
TW359669B (en) * 1995-12-15 1999-06-01 Otsuka Pharma Co Ltd Benzazepine derivatives
JPH09221476A (ja) 1995-12-15 1997-08-26 Otsuka Pharmaceut Co Ltd 医薬組成物
JPH09221475A (ja) 1996-02-13 1997-08-26 Yamanouchi Pharmaceut Co Ltd 新規なオキシム誘導体
AR011913A1 (es) * 1997-03-06 2000-09-13 Yamano Masaki Derivados de 4,4-difluoro-2,3,4,5-tetrahidro-1h-1-benzoazepina y composiciones farmaceuticas de los mismos.
JP2926335B2 (ja) 1997-06-13 1999-07-28 大塚製薬株式会社 医薬組成物
AU8592598A (en) 1997-07-30 1999-02-22 Wyeth Tricyclic vasopressin agonists
BR9811585A (pt) 1997-07-30 2000-09-26 American Home Prod Agonistas de vasopressinas tricìclicas
US6547395B1 (en) * 1998-02-06 2003-04-15 Wavefront Sciences, Inc. Methods of measuring moving objects and reducing exposure during wavefront measurements
DE60001054T2 (de) 1999-02-04 2003-07-24 Wyeth, Madison Trizyclische pyridin n-oxide vasopressin agonisten
GB0000079D0 (en) * 2000-01-05 2000-02-23 Ferring Bv Novel antidiuretic agents
HUP0402235A2 (hu) 2001-11-16 2005-02-28 Yamanouchi Pharmaceutical Co., Ltd. 4,4-Difluor-1,2,3,4-tetrahidro-5H-1-benzazepin-származékok és ezek sói és ezeket tartalmazó gyógyszerkészítmények
SI1619185T1 (sl) 2003-04-28 2011-09-30 Astellas Pharma Inc 4,4-difluoro-1,2,3,4-tetrahidro-5H-1-benzazepinski derivat ali njegova sol

Also Published As

Publication number Publication date
US7807664B2 (en) 2010-10-05
EP1619185A1 (de) 2006-01-25
US20060122170A1 (en) 2006-06-08
PL1619185T3 (pl) 2011-12-30
CA2521492A1 (en) 2004-11-11
US20070167429A1 (en) 2007-07-19
AU2004234258A1 (en) 2004-11-11
IL171332A (en) 2011-03-31
KR20060007402A (ko) 2006-01-24
PT1619185E (pt) 2011-08-25
BRPI0409718A (pt) 2006-05-02
EP1619185B1 (de) 2011-06-15
EP1619185A4 (de) 2008-07-23
NO20055602D0 (no) 2005-11-25
RU2005136863A (ru) 2006-04-20
RU2326868C2 (ru) 2008-06-20
DK1619185T3 (da) 2011-07-18
WO2004096775A1 (ja) 2004-11-11
NO20055602L (no) 2006-01-24
SI1619185T1 (sl) 2011-09-30
US7183271B2 (en) 2007-02-27
KR100882154B1 (ko) 2009-02-06
MXPA05011521A (es) 2006-01-23
AU2004234258B2 (en) 2009-04-09
NZ542815A (en) 2009-01-31
CA2521492C (en) 2010-09-21
ATE512951T1 (de) 2011-07-15

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