NO774408L - Fermenteringsprosess. - Google Patents

Fermenteringsprosess.

Info

Publication number: NO774408L
Authority: NO; Norway
Prior art keywords: stated; species; carried out; penicillium; substrate
Prior art date: 1977-01-13

Application number

NO774408A

Other languages

English (en)

Norwegian (no)

Inventor

David Cecil Aldridge

Roger Bowling

John Charles Swait

Original Assignee

Ici Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1977-01-13

Filing date

1977-12-21

Publication date

1978-07-14

1977-01-13 Priority claimed from GB1310/77A external-priority patent/GB1593389A/en

1977-12-21 Application filed by Ici Ltd filed Critical Ici Ltd

1978-07-14 Publication of NO774408L publication Critical patent/NO774408L/no

Links

238000000855 fermentation Methods 0.000 title claims description 21
230000004151 fermentation Effects 0.000 title claims description 21
239000000758 substrate Substances 0.000 claims description 32
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims description 30
238000000034 method Methods 0.000 claims description 27
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims description 18
239000000706 filtrate Substances 0.000 claims description 17
235000015097 nutrients Nutrition 0.000 claims description 17
239000000284 extract Substances 0.000 claims description 14
241000425893 Penicillium arenicola Species 0.000 claims description 13
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 claims description 12
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 12
KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 11
241000894007 species Species 0.000 claims description 11
241000228143 Penicillium Species 0.000 claims description 9
238000004519 manufacturing process Methods 0.000 claims description 9
229910052757 nitrogen Inorganic materials 0.000 claims description 9
230000001105 regulatory effect Effects 0.000 claims description 8
241000228212 Aspergillus Species 0.000 claims description 7
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 7
238000000605 extraction Methods 0.000 claims description 7
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 6
HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 6
229910052799 carbon Inorganic materials 0.000 claims description 6
241000981378 Aspergillus terricola var. indicus Species 0.000 claims description 5
238000001704 evaporation Methods 0.000 claims description 5
239000008103 glucose Substances 0.000 claims description 5
239000003960 organic solvent Substances 0.000 claims description 5
NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims description 4
QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 4
FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 3
150000003863 ammonium salts Chemical class 0.000 claims description 3
239000000872 buffer Substances 0.000 claims description 3
230000008020 evaporation Effects 0.000 claims description 3
235000019266 sodium hydrogen malate Nutrition 0.000 claims description 3
239000001394 sodium malate Substances 0.000 claims description 3
DOJOZCIMYABYPO-UHFFFAOYSA-M sodium;3,4-dihydroxy-4-oxobutanoate Chemical compound [Na+].OC(=O)C(O)CC([O-])=O DOJOZCIMYABYPO-UHFFFAOYSA-M 0.000 claims description 3
DKPFZGUDAPQIHT-UHFFFAOYSA-N Butyl acetate Natural products CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 claims description 2
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 2
229930006000 Sucrose Natural products 0.000 claims description 2
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 claims description 2
229940041514 candida albicans extract Drugs 0.000 claims description 2
238000001914 filtration Methods 0.000 claims description 2
FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 claims description 2
235000013379 molasses Nutrition 0.000 claims description 2
230000000737 periodic effect Effects 0.000 claims description 2
239000001509 sodium citrate Substances 0.000 claims description 2
239000005720 sucrose Substances 0.000 claims description 2
239000011975 tartaric acid Substances 0.000 claims description 2
235000002906 tartaric acid Nutrition 0.000 claims description 2
HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 claims description 2
229940038773 trisodium citrate Drugs 0.000 claims description 2
239000012138 yeast extract Substances 0.000 claims description 2
CYDQOEWLBCCFJZ-UHFFFAOYSA-N 4-(4-fluorophenyl)oxane-4-carboxylic acid Chemical compound C=1C=C(F)C=CC=1C1(C(=O)O)CCOCC1 CYDQOEWLBCCFJZ-UHFFFAOYSA-N 0.000 claims 1
FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims 1
229910000147 aluminium phosphate Inorganic materials 0.000 claims 1
239000001540 sodium lactate Substances 0.000 claims 1
229940005581 sodium lactate Drugs 0.000 claims 1
235000011088 sodium lactate Nutrition 0.000 claims 1
239000002904 solvent Substances 0.000 claims 1
235000019263 trisodium citrate Nutrition 0.000 claims 1
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 12
150000001875 compounds Chemical class 0.000 description 8
239000000203 mixture Substances 0.000 description 7
239000007787 solid Substances 0.000 description 7
229920001817 Agar Polymers 0.000 description 6
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
244000061456 Solanum tuberosum Species 0.000 description 6
235000002595 Solanum tuberosum Nutrition 0.000 description 6
239000008272 agar Substances 0.000 description 6
239000011734 sodium Substances 0.000 description 5
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
238000005481 NMR spectroscopy Methods 0.000 description 4
208000025865 Ulcer Diseases 0.000 description 4
230000000694 effects Effects 0.000 description 4
239000011521 glass Substances 0.000 description 4
239000002054 inoculum Substances 0.000 description 4
238000003756 stirring Methods 0.000 description 4
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
238000004566 IR spectroscopy Methods 0.000 description 3
238000005273 aeration Methods 0.000 description 3
238000009835 boiling Methods 0.000 description 3
238000011534 incubation Methods 0.000 description 3
239000000463 material Substances 0.000 description 3
239000008223 sterile water Substances 0.000 description 3
239000000725 suspension Substances 0.000 description 3
238000004809 thin layer chromatography Methods 0.000 description 3
AKGDZWRMFDLKFE-UHFFFAOYSA-N Dihydrocanadensolide Natural products CC1C(=O)OC2C(CCCC)OC(=O)C21 AKGDZWRMFDLKFE-UHFFFAOYSA-N 0.000 description 2
XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 2
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
LGDAGYXJBDILKZ-UHFFFAOYSA-N [2-methyl-1,1-dioxo-3-(pyridin-2-ylcarbamoyl)-1$l^{6},2-benzothiazin-4-yl] 2,2-dimethylpropanoate Chemical class CC(C)(C)C(=O)OC=1C2=CC=CC=C2S(=O)(=O)N(C)C=1C(=O)NC1=CC=CC=N1 LGDAGYXJBDILKZ-UHFFFAOYSA-N 0.000 description 2
229940008396 carrot extract Drugs 0.000 description 2
IJOOHPMOJXWVHK-UHFFFAOYSA-N chlorotrimethylsilane Chemical compound C[Si](C)(C)Cl IJOOHPMOJXWVHK-UHFFFAOYSA-N 0.000 description 2
239000008367 deionised water Substances 0.000 description 2
229910021641 deionized water Inorganic materials 0.000 description 2
208000000718 duodenal ulcer Diseases 0.000 description 2
239000003208 petroleum Substances 0.000 description 2
BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Chemical compound [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 description 2
235000012015 potatoes Nutrition 0.000 description 2
239000011573 trace mineral Substances 0.000 description 2
235000013619 trace mineral Nutrition 0.000 description 2
125000000026 trimethylsilyl group Chemical group [H]C([H])([H])[Si]([*])(C([H])([H])[H])C([H])([H])[H] 0.000 description 2
GRNOZCCBOFGDCL-UHFFFAOYSA-N 2,2,2-trichloroacetyl isocyanate Chemical compound ClC(Cl)(Cl)C(=O)N=C=O GRNOZCCBOFGDCL-UHFFFAOYSA-N 0.000 description 1
OQAOJHDQOKLLKC-UHFFFAOYSA-N 2-(2-oxooxolan-3-yl)acetic acid Chemical compound OC(=O)CC1CCOC1=O OQAOJHDQOKLLKC-UHFFFAOYSA-N 0.000 description 1
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
239000005909 Kieselgur Substances 0.000 description 1
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
PWHULOQIROXLJO-UHFFFAOYSA-N Manganese Chemical compound [Mn] PWHULOQIROXLJO-UHFFFAOYSA-N 0.000 description 1
241001465754 Metazoa Species 0.000 description 1
ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 description 1
208000008469 Peptic Ulcer Diseases 0.000 description 1
OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
241000700159 Rattus Species 0.000 description 1
NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
SIOVKLKJSOKLIF-UHFFFAOYSA-N bis(trimethylsilyl)acetamide Chemical compound C[Si](C)(C)OC(C)=N[Si](C)(C)C SIOVKLKJSOKLIF-UHFFFAOYSA-N 0.000 description 1
238000006243 chemical reaction Methods 0.000 description 1
239000012141 concentrate Substances 0.000 description 1
229910052802 copper Inorganic materials 0.000 description 1
239000010949 copper Substances 0.000 description 1
MNNHAPBLZZVQHP-UHFFFAOYSA-N diammonium hydrogen phosphate Chemical compound [NH4+].[NH4+].OP([O-])([O-])=O MNNHAPBLZZVQHP-UHFFFAOYSA-N 0.000 description 1
229910000388 diammonium phosphate Inorganic materials 0.000 description 1
235000019838 diammonium phosphate Nutrition 0.000 description 1
AKGDZWRMFDLKFE-BZNPZCIMSA-N dihydrocanadensolide Chemical compound C[C@H]1C(=O)O[C@@H]2[C@H](CCCC)OC(=O)[C@@H]21 AKGDZWRMFDLKFE-BZNPZCIMSA-N 0.000 description 1
210000001198 duodenum Anatomy 0.000 description 1
239000007789 gas Substances 0.000 description 1
230000035876 healing Effects 0.000 description 1
239000004615 ingredient Substances 0.000 description 1
238000011081 inoculation Methods 0.000 description 1
230000003993 interaction Effects 0.000 description 1
229910052742 iron Inorganic materials 0.000 description 1
239000011777 magnesium Substances 0.000 description 1
229910052749 magnesium Inorganic materials 0.000 description 1
ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 1
239000001095 magnesium carbonate Substances 0.000 description 1
229910000021 magnesium carbonate Inorganic materials 0.000 description 1
229910052943 magnesium sulfate Inorganic materials 0.000 description 1
CSNNHWWHGAXBCP-UHFFFAOYSA-L magnesium sulphate Substances [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 1
235000019341 magnesium sulphate Nutrition 0.000 description 1
230000014759 maintenance of location Effects 0.000 description 1
229910052748 manganese Inorganic materials 0.000 description 1
239000011572 manganese Substances 0.000 description 1
229910052751 metal Inorganic materials 0.000 description 1
239000002184 metal Substances 0.000 description 1
150000007522 mineralic acids Chemical class 0.000 description 1
XONPDZSGENTBNJ-UHFFFAOYSA-N molecular hydrogen;sodium Chemical compound [Na].[H][H] XONPDZSGENTBNJ-UHFFFAOYSA-N 0.000 description 1
229910052750 molybdenum Inorganic materials 0.000 description 1
239000011733 molybdenum Substances 0.000 description 1
229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
235000019796 monopotassium phosphate Nutrition 0.000 description 1
238000000655 nuclear magnetic resonance spectrum Methods 0.000 description 1
239000002420 orchard Substances 0.000 description 1
150000007524 organic acids Chemical class 0.000 description 1
125000001477 organic nitrogen group Chemical group 0.000 description 1
208000011906 peptic ulcer disease Diseases 0.000 description 1
239000000825 pharmaceutical preparation Substances 0.000 description 1
238000005191 phase separation Methods 0.000 description 1
PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 description 1
229910052698 phosphorus Inorganic materials 0.000 description 1
239000011574 phosphorus Substances 0.000 description 1
239000011591 potassium Substances 0.000 description 1
229910052700 potassium Inorganic materials 0.000 description 1
229910000027 potassium carbonate Inorganic materials 0.000 description 1
239000001103 potassium chloride Substances 0.000 description 1
235000011164 potassium chloride Nutrition 0.000 description 1
WCUXLLCKKVVCTQ-UHFFFAOYSA-M potassium chloride Inorganic materials [Cl-].[K+] WCUXLLCKKVVCTQ-UHFFFAOYSA-M 0.000 description 1
238000001556 precipitation Methods 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
239000000047 product Substances 0.000 description 1
UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
239000000741 silica gel Substances 0.000 description 1
229910002027 silica gel Inorganic materials 0.000 description 1
229920002379 silicone rubber Polymers 0.000 description 1
239000004945 silicone rubber Substances 0.000 description 1
229910052708 sodium Inorganic materials 0.000 description 1
229940083542 sodium Drugs 0.000 description 1
PPASLZSBLFJQEF-RKJRWTFHSA-M sodium ascorbate Substances [Na+].OC[C@@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RKJRWTFHSA-M 0.000 description 1
239000011343 solid material Substances 0.000 description 1
230000003595 spectral effect Effects 0.000 description 1
238000007920 subcutaneous administration Methods 0.000 description 1
229910052717 sulfur Inorganic materials 0.000 description 1
239000011593 sulfur Substances 0.000 description 1
229910021653 sulphate ion Inorganic materials 0.000 description 1
CZDYPVPMEAXLPK-UHFFFAOYSA-N tetramethylsilane Chemical compound C[Si](C)(C)C CZDYPVPMEAXLPK-UHFFFAOYSA-N 0.000 description 1
231100000419 toxicity Toxicity 0.000 description 1
230000001988 toxicity Effects 0.000 description 1
239000005051 trimethylchlorosilane Substances 0.000 description 1
231100000397 ulcer Toxicity 0.000 description 1
238000005406 washing Methods 0.000 description 1
239000011701 zinc Substances 0.000 description 1
229910052725 zinc Inorganic materials 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/04—Oxygen as only ring hetero atoms containing a five-membered hetero ring, e.g. griseofulvin, vitamin C
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/933—Penicillium

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Wood Science & Technology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

NO774408A 1977-01-13 1977-12-21 Fermenteringsprosess. NO774408L (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB1310/77A GB1593389A (en)	1977-01-13	1977-01-13	Fermentation process
GB1062277		1977-03-14

Publications (1)

Publication Number	Publication Date
NO774408L true NO774408L (no)	1978-07-14

Family

ID=26236635

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO774408A NO774408L (no)	1977-01-13	1977-12-21	Fermenteringsprosess.

Country Status (16)

Country	Link
US (1)	US4178213A (da)
JP (1)	JPS53109995A (da)
AU (1)	AU3225078A (da)
CA (1)	CA1108078A (da)
DE (1)	DE2801399A1 (da)
DK (1)	DK4978A (da)
ES (1)	ES465948A1 (da)
FI (1)	FI780041A7 (da)
FR (1)	FR2377449A1 (da)
GR (1)	GR62086B (da)
IE (1)	IE45855B1 (da)
IT (1)	IT1158425B (da)
NL (1)	NL7800243A (da)
NO (1)	NO774408L (da)
NZ (1)	NZ186138A (da)
SE (1)	SE7800363L (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2583310A1 (en) *	2004-10-05	2006-04-13	Biocon Limited	Process for producing mycophenolic acid using penicillium arenicola bicc7673
CN101831470A (zh) *	2010-04-26	2010-09-15	华南理工大学	二氢双环内酯的制备方法及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1434595A (en) *	1973-03-29	1976-05-05	Ici Ltd	Pharmaceutical compositions

1977
- 1977-12-20 IE IE2580/77A patent/IE45855B1/en unknown
- 1977-12-21 NO NO774408A patent/NO774408L/no unknown
- 1977-12-27 US US05/864,473 patent/US4178213A/en not_active Expired - Lifetime
- 1977-12-29 CA CA294,038A patent/CA1108078A/en not_active Expired
1978
- 1978-01-05 NZ NZ186138A patent/NZ186138A/xx unknown
- 1978-01-05 DK DK4978A patent/DK4978A/da unknown
- 1978-01-06 FI FI780041A patent/FI780041A7/fi not_active Application Discontinuation
- 1978-01-09 GR GR55122A patent/GR62086B/el unknown
- 1978-01-09 NL NL7800243A patent/NL7800243A/xx not_active Application Discontinuation
- 1978-01-09 AU AU32250/78A patent/AU3225078A/en active Pending
- 1978-01-12 SE SE7800363A patent/SE7800363L/xx unknown
- 1978-01-12 FR FR7800816A patent/FR2377449A1/fr not_active Withdrawn
- 1978-01-13 ES ES465948A patent/ES465948A1/es not_active Expired
- 1978-01-13 DE DE19782801399 patent/DE2801399A1/de not_active Withdrawn
- 1978-01-13 IT IT19260/78A patent/IT1158425B/it active
- 1978-01-13 JP JP326578A patent/JPS53109995A/ja active Pending

Also Published As

Publication number	Publication date
AU3225078A (en)	1979-07-19
FI780041A7 (fi)	1978-07-14
US4178213A (en)	1979-12-11
GR62086B (en)	1979-02-21
FR2377449A1 (fr)	1978-08-11
IE45855B1 (en)	1982-12-15
CA1108078A (en)	1981-09-01
DE2801399A1 (de)	1978-07-20
IT7819260A0 (it)	1978-01-13
NL7800243A (nl)	1978-07-17
NZ186138A (en)	1979-06-19
IE45855L (en)	1978-07-13
IT1158425B (it)	1987-02-18
SE7800363L (sv)	1978-07-14
ES465948A1 (es)	1979-01-01
DK4978A (da)	1978-07-14
JPS53109995A (en)	1978-09-26

Publication	Publication Date	Title
IL34956A (en)	1973-03-30	Production of lipase
DK145701B (da)	1983-01-31	Fremgangsmaade til fremstilling af ergotalkaloider
DK165124B (da)	1992-10-12	Fremgangsmaade til fremstilling af en 5-hydroxy-s541-macrolidforbindelse
GB2031896A (en)	1980-04-30	A process for the optical resolution of D,L-2-amino-4- methylphosphinobutyric acid
NO774408L (no)	1978-07-14	Fermenteringsprosess.
FR2681601A1 (fr)	1993-03-26	Polysaccharide, ses applications, son obtention par fermentation, souche de pseudomonas le produisant.
DK151273B (da)	1987-11-16	Fremgangsmaade til fremstilling af cholesterolbiosynteseinhibitoren mb- 530a.
JP3081901B2 (ja)	2000-08-28	γ−ポリグルタミン酸の製造法
JPH0427237B2 (da)	1992-05-11
IL30058A (en)	1972-09-28	Process for preparing antibiotic a10388(pyrrolnitrin)
SU888542A1 (ru)	1983-08-15	Способ получени ферментного препарата липоксигеназы
FR2476128A1 (fr)	1981-08-21	Procede microbiologique de production de narasine et cultures contenant le microorganisme producteur streptomyces lydicus deboer et al-
US3661712A (en)	1972-05-09	Process for producing zearalenone
US3898133A (en)	1975-08-05	Process of preparing an enzyme with lipolytic activity
NO760873L (da)	1976-09-14
KR820000295B1 (ko)	1982-03-19	코엔자임 q의 제조방법
JP2764759B2 (ja)	1998-06-11	新規物質ｂｔ―３８物質及びその製造法並びにそれを有効成分とする抗黴剤
GB1593389A (en)	1981-07-15	Fermentation process
US3835170A (en)	1974-09-10	Hypotensive agent, oudenone, its salts and processes for production and preparation thereof
NO783877L (no)	1979-05-21	Fremgangsmaate for fremstilling av 2,5-diketoglukonsyre
JPH05331181A (ja)	1993-12-14	ファルネシルトランスフェラーゼ阻害物質ｏｈ−４６５２物質およびその製造法
JPH0117672B2 (da)	1989-03-31
JPS6359678B2 (da)	1988-11-21
JPH07206886A (ja)	1995-08-08	ファルネシルトランスフェラーゼ阻害物質ｆｏ−３９２９物質及びその製造法
JPH04321698A (ja)	1992-11-11	生理活性物質ｍ６１２４及びその製造方法