NO792267L - Fremgangsmaate ved fremstilling av substituerte benzapiner - Google Patents

Fremgangsmaate ved fremstilling av substituerte benzapiner

Info

Publication number: NO792267L
Authority: NO; Norway
Prior art keywords: benzapines; procedure; manufacturing substituted; substituted; manufacturing
Prior art date: 1978-07-07

Application number

NO792267A

Other languages

English (en)

Other versions

NO152213C (no

NO152213B (no

Inventor

Kenneth George Holden

Carl Kaiser

Original Assignee

Smithkline Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-07-07

Filing date

1979-07-06

Publication date

1980-01-08

1979-07-06 Application filed by Smithkline Corp filed Critical Smithkline Corp

1980-01-08 Publication of NO792267L publication Critical patent/NO792267L/no

1985-05-13 Publication of NO152213B publication Critical patent/NO152213B/no

1985-08-28 Publication of NO152213C publication Critical patent/NO152213C/no

Links

238000004519 manufacturing process Methods 0.000 title 1
238000000034 method Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/22—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of halogens; by substitution of halogen atoms by other halogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
- C07C41/26—Preparation of ethers by reactions not forming ether-oxygen bonds by introduction of hydroxy or O-metal groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/022—Boron compounds without C-boron linkages

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Anesthesiology (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Other In-Based Heterocyclic Compounds (AREA)

NO792267A 1978-07-07 1979-07-06 Analogifremgangsmaate ved fremstilling av terapeutisk aktive substituerte benzazepiner NO152213C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US92261378A	1978-07-07	1978-07-07

Publications (3)

Publication Number	Publication Date
NO792267L true NO792267L (no)	1980-01-08
NO152213B NO152213B (no)	1985-05-13
NO152213C NO152213C (no)	1985-08-28

Family

ID=25447325

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO792267A NO152213C (no)	1978-07-07	1979-07-06	Analogifremgangsmaate ved fremstilling av terapeutisk aktive substituerte benzazepiner

Country Status (24)

Country	Link
EP (2)	EP0007070B1 (no)
JP (1)	JPS5511584A (no)
AR (1)	AR222828A1 (no)
AU (1)	AU525789B2 (no)
CA (1)	CA1115271A (no)
CS (1)	CS213381B2 (no)
DD (1)	DD147355A5 (no)
DE (1)	DE2964530D1 (no)
DK (1)	DK156001C (no)
ES (3)	ES482282A1 (no)
FI (1)	FI67215C (no)
GR (1)	GR69675B (no)
HU (1)	HU179315B (no)
IE (1)	IE48654B1 (no)
IL (1)	IL57532A (no)
IT (1)	IT1193190B (no)
JO (1)	JO1273B1 (no)
NO (1)	NO152213C (no)
NZ (1)	NZ190745A (no)
PH (1)	PH15754A (no)
PL (1)	PL216908A1 (no)
PT (1)	PT69855A (no)
SU (1)	SU1029827A3 (no)
ZA (1)	ZA792785B (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3119874A1 (de)	1981-05-19	1982-12-09	Dr. Karl Thomae Gmbh, 7950 Biberach	"benzazepinderivate, ihre herstellung und ihre verwendung als arzneimittel"
US4469634A (en) *	1982-07-29	1984-09-04	Smithkline Beckman Corporation	Allyloxy- and allylthio-2,3,4,5-tetrahydro-1H-3-benzazepines
US4652642A (en) *	1984-08-23	1987-03-24	Smithkline Beckman Corporation	Azidobenzazepines
US4683229A (en) *	1986-03-17	1987-07-28	Smithkline Beckman Corporation	6-halo-9-alkenyleneoxy-3-alkyl-2,3,4,5-tetrahydro-(1H-3)-benzazepines and their use as selective alpha-adrenergic receptor antagonists
US5942250A (en) *	1986-12-23	1999-08-24	Tristrata Technology, Inc.	Compositions and methods for enhancing the topical effects of sunscreen agents
US6384079B1 (en)	1986-12-23	2002-05-07	Tristrata Technology, Incorporated	Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging
GB9119467D0 (en) *	1991-09-12	1991-10-23	Smithkline Beecham Corp	Chemical compounds
GB9708805D0 (en)	1997-05-01	1997-06-25	Smithkline Beecham Plc	Compounds
GB9810876D0 (en)	1998-05-20	1998-07-22	Smithkline Beecham Plc	Compounds
CA2346689A1 (en)	1998-10-08	2000-04-20	Gregor James Macdonald	Tetrahydrobenzazepine derivatives useful as modulators of dopamine d3 receptors (antipsychotic agents)
US6953787B2 (en)	2002-04-12	2005-10-11	Arena Pharmaceuticals, Inc.	5HT2C receptor modulators
ATE327234T1 (de) *	2002-10-07	2006-06-15	Glaxo Group Ltd	Sulfonamidderivate als antipsychotische mittel
US8367657B2 (en)	2003-06-17	2013-02-05	Arena Pharmaceuticals, Inc.	Processes for preparing 3-benzazepines
CN1805938B (zh)	2003-06-17	2010-06-16	艾尼纳制药公司	用于治疗5ht2c受体相关疾病的苯并氮杂卓衍生物
CA2556390C (en) *	2004-02-25	2012-10-02	Eli Lilly And Company	6-substituted 2,3,4,5-tetrahydro-1h-benzo[d]azepines as 5-ht2c receptor agonists
EP2149562A1 (en)	2004-12-21	2010-02-03	Arena Pharmaceuticals, Inc.	method of preparing (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate
NZ589951A (en)	2004-12-23	2012-11-30	Arena Pharm Inc	5HT2C receptor modulator compositions and methods of use
CA2646044A1 (en)	2006-04-03	2007-10-25	Arena Pharmaceuticals, Inc.	Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates related thereto
EP2099743B1 (en)	2006-12-05	2014-08-27	Arena Pharmaceuticals, Inc.	Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof
US8822727B2 (en)	2008-03-04	2014-09-02	Arena Pharmaceuticals, Inc.	Processes for the preparation of intermediates related to the 5-HT2C agonist (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
WO2010148207A2 (en)	2009-06-18	2010-12-23	Arena Pharmaceuticals, Inc.	Processes for the preparation of 5-ht2c receptor agonists
WO2011153206A1 (en)	2010-06-02	2011-12-08	Arena Pharmaceuticals, Inc.	Processes for the preparation of 5-ht2c receptor agonists
JP2013539470A (ja)	2010-09-01	2013-10-24	アリーナファーマシューティカルズ，インコーポレイテッド	ロルカセリンと光学活性な酸との塩
EA201390335A1 (ru)	2010-09-01	2013-09-30	Арена Фармасьютикалз, Инк.	Введение лоркасерина индивидуумам с почечной недостаточностью
KR20130101524A (ko)	2010-09-01	2013-09-13	아레나 파마슈티칼스, 인크.	5-ｈｔ2ｃ 아고니스트의 비-흡습성 염
KR20180118801A (ko)	2010-09-01	2018-10-31	에자이 알앤드디 매니지먼트 가부시키가이샤	체중 관리에 유용한 5-ｈｔ2ｃ 작동제의 변형-방출 투여 형태
RU2674670C1 (ru)	2012-10-09	2018-12-12	Арена Фармасьютикалз, Инк.	Способ коррекции массы тела
CN116655892B (zh) *	2023-05-18	2026-03-31	常州大学	一种交联聚合物有机电极材料及其制备方法与应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2520264A (en) *	1947-08-26	1950-08-29	Maltbie Lab Inc	Substituted 3, 1-benz-2, 3, 4, 5-tetrahydroazepines
US3483185A (en) *	1966-08-16	1969-12-09	American Home Prod	N-substituted 2,3,4,5-tetrahydro-1h-3-benzazepines
CA974989A (en) *	1968-03-11	1975-09-23	Wallace And Tiernan Inc.	Process for preparing 1,2,4,5-tetrahydro-3h,3-benzazepines and products obtained thereby
US3671519A (en)	1969-07-14	1972-06-20	American Home Prod	N-substituted 2,3,4,5,-tetrahydro-1h-3-benzazepines
US3716639A (en)	1970-03-11	1973-02-13	Ciba Geigy Corp	Anorexigenic tetrahydrobenzazepines
US3752892A (en)	1970-03-11	1973-08-14	Ciba Geigy Corp	Anorexigenic tetrahydrobenzazepine derivative method and composition thereof
US4111957A (en) *	1977-02-02	1978-09-05	Smithkline Corporation	Substituted 1-thienyl and furyl-2,3,4,5-tetrahydro-1H-3-benzazepine compounds
US4108989A (en) *	1977-04-01	1978-08-22	Smithkline Corporation	2,3,4,5-tetrahydro-1h-3-benzazepine-7,8-diones

1979
- 1979-06-05 ZA ZA792785A patent/ZA792785B/xx unknown
- 1979-06-11 IL IL57532A patent/IL57532A/xx unknown
- 1979-06-15 NZ NZ190745A patent/NZ190745A/xx unknown
- 1979-06-28 JP JP8252779A patent/JPS5511584A/ja active Granted
- 1979-07-02 PH PH22728A patent/PH15754A/en unknown
- 1979-07-02 PT PT69855A patent/PT69855A/pt unknown
- 1979-07-02 DK DK278379A patent/DK156001C/da not_active IP Right Cessation
- 1979-07-02 CS CS794635A patent/CS213381B2/cs unknown
- 1979-07-03 GR GR59498A patent/GR69675B/el unknown
- 1979-07-03 CA CA331,022A patent/CA1115271A/en not_active Expired
- 1979-07-03 AU AU48613/79A patent/AU525789B2/en not_active Ceased
- 1979-07-04 EP EP79102279A patent/EP0007070B1/en not_active Expired
- 1979-07-04 EP EP82105188A patent/EP0080012B1/en not_active Expired
- 1979-07-04 DE DE7979102279T patent/DE2964530D1/de not_active Expired
- 1979-07-05 FI FI792125A patent/FI67215C/fi not_active IP Right Cessation
- 1979-07-05 HU HU79SI1705A patent/HU179315B/hu unknown
- 1979-07-06 ES ES482282A patent/ES482282A1/es not_active Expired
- 1979-07-06 AR AR277218A patent/AR222828A1/es active
- 1979-07-06 IT IT24165/79A patent/IT1193190B/it active
- 1979-07-06 PL PL21690879A patent/PL216908A1/xx unknown
- 1979-07-06 SU SU792783746A patent/SU1029827A3/ru active
- 1979-07-06 ES ES482276A patent/ES482276A1/es not_active Expired
- 1979-07-06 ES ES482281A patent/ES482281A1/es not_active Expired
- 1979-07-06 DD DD79214179A patent/DD147355A5/de unknown
- 1979-07-06 NO NO792267A patent/NO152213C/no unknown
- 1979-07-07 JO JO19791273A patent/JO1273B1/en active
- 1979-08-08 IE IE1276/79A patent/IE48654B1/en unknown

Also Published As

Publication number	Publication date
AU525789B2 (en)	1982-12-02
JPS5511584A (en)	1980-01-26
ZA792785B (en)	1980-08-27
IE48654B1 (en)	1985-04-03
IL57532A0 (en)	1979-10-31
EP0080012A1 (en)	1983-06-01
EP0080012B1 (en)	1986-04-09
ES482282A1 (es)	1980-04-01
FI67215B (fi)	1984-10-31
EP0007070A1 (en)	1980-01-23
HU179315B (en)	1982-09-28
SU1029827A3 (ru)	1983-07-15
ES482281A1 (es)	1980-04-01
CS213381B2 (en)	1982-04-09
NO152213C (no)	1985-08-28
FI792125A7 (fi)	1980-01-08
FI67215C (fi)	1985-02-11
CA1115271A (en)	1981-12-29
PL216908A1 (no)	1980-08-11
JPH0153271B2 (no)	1989-11-13
ES482276A1 (es)	1980-04-01
JO1273B1 (en)	1986-11-30
DK156001B (da)	1989-06-12
PT69855A (en)	1979-08-01
DD147355A5 (de)	1981-04-01
EP0007070B1 (en)	1983-01-19
IE791276L (en)	1980-01-07
DK278379A (da)	1980-01-08
NZ190745A (en)	1981-01-23
NO152213B (no)	1985-05-13
PH15754A (en)	1983-03-18
IT7924165A0 (it)	1979-07-06
GR69675B (no)	1982-07-07
AR222828A1 (es)	1981-06-30
IT1193190B (it)	1988-06-02
DE2964530D1 (en)	1983-02-24
IL57532A (en)	1982-08-31
DK156001C (da)	1989-11-06
AU4861379A (en)	1980-02-07

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FI780514A7 (fi)	1979-08-17	Foerfarande och slipverk foer slipning av ved under tryck
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