NO793501L - Fremgangsmaate for fremstilling av et antihemofilifaktorpreparat fra menneskeblodplasma - Google Patents

Fremgangsmaate for fremstilling av et antihemofilifaktorpreparat fra menneskeblodplasma

Info

Publication number: NO793501L
Authority: NO; Norway
Prior art keywords: plasma; thawed; preparation; irradiation; blood plasma
Prior art date: 1978-11-01

Application number

NO793501A

Other languages

English (en)

Norwegian (no)

Inventor

Mirella Ezban Rasmussen

Joergen Vikelsoee Jensen

Joergen Frederik Hansen

Original Assignee

Nordisk Insulinlab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1978-11-01

Filing date

1979-10-31

Publication date

1980-05-05

1979-10-31 Application filed by Nordisk Insulinlab filed Critical Nordisk Insulinlab

1980-05-05 Publication of NO793501L publication Critical patent/NO793501L/no

Links

210000002381 plasma Anatomy 0.000 title claims abstract description 43
238000002360 preparation method Methods 0.000 title claims abstract description 35
238000000034 method Methods 0.000 title claims abstract description 17
238000010257 thawing Methods 0.000 claims description 22
239000000047 product Substances 0.000 claims description 8
208000031220 Hemophilia Diseases 0.000 claims description 7
208000009292 Hemophilia A Diseases 0.000 claims description 7
239000002244 precipitate Substances 0.000 claims description 6
238000005119 centrifugation Methods 0.000 claims description 4
238000004519 manufacturing process Methods 0.000 claims description 4
230000005855 radiation Effects 0.000 claims description 3
238000004090 dissolution Methods 0.000 claims 2
238000002955 isolation Methods 0.000 claims 2
230000000603 anti-haemophilic effect Effects 0.000 claims 1
239000000243 solution Substances 0.000 description 7
102000001690 Factor VIII Human genes 0.000 description 5
108010054218 Factor VIII Proteins 0.000 description 5
JTJMJGYZQZDUJJ-UHFFFAOYSA-N phencyclidine Chemical compound C1CCCCN1C1(C=2C=CC=CC=2)CCCCC1 JTJMJGYZQZDUJJ-UHFFFAOYSA-N 0.000 description 5
238000012545 processing Methods 0.000 description 5
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
102000008946 Fibrinogen Human genes 0.000 description 4
108010049003 Fibrinogen Proteins 0.000 description 4
229940012952 fibrinogen Drugs 0.000 description 4
238000010438 heat treatment Methods 0.000 description 4
102000015081 Blood Coagulation Factors Human genes 0.000 description 3
108010039209 Blood Coagulation Factors Proteins 0.000 description 3
102000004506 Blood Proteins Human genes 0.000 description 3
108010017384 Blood Proteins Proteins 0.000 description 3
208000032843 Hemorrhage Diseases 0.000 description 3
208000034158 bleeding Diseases 0.000 description 3
230000000740 bleeding effect Effects 0.000 description 3
239000003114 blood coagulation factor Substances 0.000 description 3
229960000301 factor viii Drugs 0.000 description 3
238000001802 infusion Methods 0.000 description 3
IJRKANNOPXMZSG-SSPAHAAFSA-N 2-hydroxypropane-1,2,3-tricarboxylic acid;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O.OC(=O)CC(O)(C(O)=O)CC(O)=O IJRKANNOPXMZSG-SSPAHAAFSA-N 0.000 description 2
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
YTCZZXIRLARSET-VJRSQJMHSA-M beraprost sodium Chemical compound [Na+].O([C@H]1C[C@@H](O)[C@@H]([C@@H]21)/C=C/[C@@H](O)C(C)CC#CC)C1=C2C=CC=C1CCCC([O-])=O YTCZZXIRLARSET-VJRSQJMHSA-M 0.000 description 2
230000004071 biological effect Effects 0.000 description 2
230000023555 blood coagulation Effects 0.000 description 2
229940105778 coagulation factor viii Drugs 0.000 description 2
238000004925 denaturation Methods 0.000 description 2
230000036425 denaturation Effects 0.000 description 2
230000000694 effects Effects 0.000 description 2
238000001914 filtration Methods 0.000 description 2
238000002347 injection Methods 0.000 description 2
239000007924 injection Substances 0.000 description 2
239000007858 starting material Substances 0.000 description 2
241000931365 Ampelodesmos mauritanicus Species 0.000 description 1
KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
201000003542 Factor VIII deficiency Diseases 0.000 description 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
206010061218 Inflammation Diseases 0.000 description 1
208000027418 Wounds and injury Diseases 0.000 description 1
230000001154 acute effect Effects 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
239000008280 blood Substances 0.000 description 1
229960000182 blood factors Drugs 0.000 description 1
230000036760 body temperature Effects 0.000 description 1
238000009835 boiling Methods 0.000 description 1
230000015556 catabolic process Effects 0.000 description 1
239000013043 chemical agent Substances 0.000 description 1
230000006378 damage Effects 0.000 description 1
230000007812 deficiency Effects 0.000 description 1
230000000593 degrading effect Effects 0.000 description 1
201000010099 disease Diseases 0.000 description 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
230000005670 electromagnetic radiation Effects 0.000 description 1
238000002474 experimental method Methods 0.000 description 1
238000000605 extraction Methods 0.000 description 1
238000004108 freeze drying Methods 0.000 description 1
238000007710 freezing Methods 0.000 description 1
230000008014 freezing Effects 0.000 description 1
239000008103 glucose Substances 0.000 description 1
208000002085 hemarthrosis Diseases 0.000 description 1
208000031169 hemorrhagic disease Diseases 0.000 description 1
230000002439 hemostatic effect Effects 0.000 description 1
230000001771 impaired effect Effects 0.000 description 1
230000004054 inflammatory process Effects 0.000 description 1
230000000977 initiatory effect Effects 0.000 description 1
150000002500 ions Chemical class 0.000 description 1
239000007788 liquid Substances 0.000 description 1
230000005923 long-lasting effect Effects 0.000 description 1
230000007774 longterm Effects 0.000 description 1
230000007246 mechanism Effects 0.000 description 1
230000035515 penetration Effects 0.000 description 1
238000001556 precipitation Methods 0.000 description 1
238000004321 preservation Methods 0.000 description 1
ZMRUPTIKESYGQW-UHFFFAOYSA-N propranolol hydrochloride Chemical compound [H+].[Cl-].C1=CC=C2C(OCC(O)CNC(C)C)=CC=CC2=C1 ZMRUPTIKESYGQW-UHFFFAOYSA-N 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
238000012958 reprocessing Methods 0.000 description 1
238000001356 surgical procedure Methods 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01R—ELECTRICALLY-CONDUCTIVE CONNECTIONS; STRUCTURAL ASSOCIATIONS OF A PLURALITY OF MUTUALLY-INSULATED ELECTRICAL CONNECTING ELEMENTS; COUPLING DEVICES; CURRENT COLLECTORS
- H01R13/00—Details of coupling devices of the kinds covered by groups H01R12/70 or H01R24/00 - H01R33/00
- H01R13/46—Bases; Cases
- H01R13/52—Dustproof, splashproof, drip-proof, waterproof, or flameproof cases
- H01R13/5219—Sealing means between coupling parts, e.g. interfacial seal
- H01R13/5221—Sealing means between coupling parts, e.g. interfacial seal having cable sealing means
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
- Y10S530/83—Plasma; serum

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
Zoology (AREA)
Biochemistry (AREA)
Toxicology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Gastroenterology & Hepatology (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Hematology (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)

NO793501A 1978-11-01 1979-10-31 Fremgangsmaate for fremstilling av et antihemofilifaktorpreparat fra menneskeblodplasma NO793501L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DK487578		1978-11-01

Publications (1)

Publication Number	Publication Date
NO793501L true NO793501L (no)	1980-05-05

Family

ID=8137444

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO793501A NO793501L (no)	1978-11-01	1979-10-31	Fremgangsmaate for fremstilling av et antihemofilifaktorpreparat fra menneskeblodplasma

Country Status (20)

Country	Link
US (1)	US4251437A (ja)
JP (1)	JPS5585523A (ja)
AR (1)	AR217576A1 (ja)
AT (1)	AT369652B (ja)
AU (1)	AU522556B2 (ja)
BE (1)	BE879733A (ja)
CA (1)	CA1119094A (ja)
DD (1)	DD146892A5 (ja)
DE (1)	DE2943512A1 (ja)
ES (1)	ES485550A1 (ja)
FI (1)	FI63521C (ja)
FR (1)	FR2440193A1 (ja)
GB (1)	GB2034327B (ja)
HU (1)	HU180898B (ja)
IL (1)	IL58541A (ja)
IT (1)	IT1162791B (ja)
NL (1)	NL7907984A (ja)
NO (1)	NO793501L (ja)
OA (1)	OA06368A (ja)
SE (1)	SE7909026L (ja)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3033932C2 (de) *	1980-09-10	1984-05-24	Biotest-Serum-Institut Gmbh, 6000 Frankfurt	Verfahren zur Kaltsterilisation von Blutgerinnungsfaktor VIII enthaltenden Präparaten
US4620908A (en) *	1983-10-03	1986-11-04	Biocell Laboratories, Inc.	Method for destroying microbial contamination in protein materials
US4839142A (en) *	1985-09-30	1989-06-13	Charm Stanley E	High temperature, short time heating system and method of sterilizing or pasteurizing heat sensitive biological fluids
US4975246A (en) *	1985-09-30	1990-12-04	Charm Stanley E	High temperature, short time heating system and method of heating heat-sensitive material
FR2634381B1 (fr) *	1988-07-25	1990-09-07	Morez Jean Bernard	Procede pour la fabrication de medicaments homeopathiques en une seule operation quelque soit la dilution choisie
WO1991010450A1 (fr) *	1990-01-11	1991-07-25	Morez Jean Bernard	Procede pour la fabrication homeopatiques en une seule operation quelque soit la dilution choisie
US6187572B1 (en)	1990-04-16	2001-02-13	Baxter International Inc.	Method of inactivation of viral and bacterial blood contaminants
US5418130A (en) *	1990-04-16	1995-05-23	Cryopharm Corporation	Method of inactivation of viral and bacterial blood contaminants
US5644032A (en) *	1990-08-06	1997-07-01	Fibrin Corporation	Process for producing fibrinogen concentrates
DE4308360C1 (de) *	1993-03-16	1994-10-27	Transmed Medtech Gmbh	Aufwärm- und Auftaugerät
US5362442A (en) *	1993-07-22	1994-11-08	2920913 Canada Inc.	Method for sterilizing products with gamma radiation
US20040067157A1 (en) *	1993-07-22	2004-04-08	Clearant, Inc.	Methods for sterilizing biological materials
US5616268A (en) *	1994-07-07	1997-04-01	Microwave Medical Systems	Microwave blood thawing with feedback control
US20020077276A1 (en) *	1999-04-27	2002-06-20	Fredeking Terry M.	Compositions and methods for treating hemorrhagic virus infections and other disorders
US20040086420A1 (en) *	2000-03-23	2004-05-06	Macphee Martin J.	Methods for sterilizing serum or plasma
US6682695B2 (en) *	2001-03-23	2004-01-27	Clearant, Inc.	Methods for sterilizing biological materials by multiple rates
US6696060B2 (en)	2001-06-14	2004-02-24	Clearant, Inc.	Methods for sterilizing preparations of monoclonal immunoglobulins
US20030031584A1 (en) *	2001-08-10	2003-02-13	Wilson Burgess	Methods for sterilizing biological materials using dipeptide stabilizers
US6946098B2 (en)	2001-08-10	2005-09-20	Clearant, Inc.	Methods for sterilizing biological materials
US7252799B2 (en)	2001-08-31	2007-08-07	Clearant, Inc.	Methods for sterilizing preparations containing albumin
US6749851B2 (en)	2001-08-31	2004-06-15	Clearant, Inc.	Methods for sterilizing preparations of digestive enzymes
US20030185702A1 (en) *	2002-02-01	2003-10-02	Wilson Burgess	Methods for sterilizing tissue
US20030095890A1 (en) *	2001-09-24	2003-05-22	Shirley Miekka	Methods for sterilizing biological materials containing non-aqueous solvents
US6783968B2 (en)	2001-09-24	2004-08-31	Clearant, Inc.	Methods for sterilizing preparations of glycosidases
US20110091353A1 (en) *	2001-09-24	2011-04-21	Wilson Burgess	Methods for Sterilizing Tissue
US20030124023A1 (en) *	2001-12-21	2003-07-03	Wilson Burgess	Method of sterilizing heart valves
US20030180181A1 (en) *	2002-02-01	2003-09-25	Teri Greib	Methods for sterilizing tissue
US20040013562A1 (en) *	2002-07-18	2004-01-22	Wilson Burgess	Methods for sterilizing milk.
US6908591B2 (en) *	2002-07-18	2005-06-21	Clearant, Inc.	Methods for sterilizing biological materials by irradiation over a temperature gradient
US20060226086A1 (en) *	2005-04-08	2006-10-12	Robinson Thomas C	Centrifuge for blood processing systems
DE202010004830U1 (de)	2010-04-10	2010-07-29	Pelster, Michael, Dipl.-Ing.	Vorrichtung zum Auftauen und/oder Erwärmen von sich in einem Behältnis befindlichen medizinischen Gut
US9173248B2 (en) *	2011-03-14	2015-10-27	Products Support, Inc.	Thawing oven

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2867567A (en) *	1955-01-21	1959-01-06	Nat Res Dev	Process of preparing anti-haemophilic globulin
US3492212A (en) *	1966-12-01	1970-01-27	Hoffmann La Roche	Ultrasonic treatment of protein materials
US3652530A (en) *	1967-08-28	1972-03-28	American Nat Red Cross	Antihemophilic factor prepared from blood plasma using polyethylene glycol
US3645849A (en) *	1969-04-17	1972-02-29	Gray Ind Inc	Stability of enzymes
FR2363577A1 (fr) *	1976-09-03	1978-03-31	Recherches Hematologiques	Procede simplifie pour preparer avec un rendement eleve du concentre de facteur antihemophilique pur

1979
- 1979-10-23 IL IL58541A patent/IL58541A/xx unknown
- 1979-10-26 AU AU52231/79A patent/AU522556B2/en not_active Ceased
- 1979-10-26 US US06/088,671 patent/US4251437A/en not_active Expired - Lifetime
- 1979-10-27 DE DE19792943512 patent/DE2943512A1/de not_active Withdrawn
- 1979-10-30 FI FI793389A patent/FI63521C/fi not_active IP Right Cessation
- 1979-10-30 GB GB7937595A patent/GB2034327B/en not_active Expired
- 1979-10-30 BE BE0/197898A patent/BE879733A/fr unknown
- 1979-10-30 IT IT26925/79A patent/IT1162791B/it active
- 1979-10-30 ES ES485550A patent/ES485550A1/es not_active Expired
- 1979-10-30 DD DD79216550A patent/DD146892A5/de unknown
- 1979-10-31 CA CA000338815A patent/CA1119094A/en not_active Expired
- 1979-10-31 AT AT0703979A patent/AT369652B/de not_active IP Right Cessation
- 1979-10-31 FR FR7927040A patent/FR2440193A1/fr active Granted
- 1979-10-31 NL NL7907984A patent/NL7907984A/nl not_active Application Discontinuation
- 1979-10-31 SE SE7909026A patent/SE7909026L/xx not_active Application Discontinuation
- 1979-10-31 NO NO793501A patent/NO793501L/no unknown
- 1979-11-01 HU HU79NO237A patent/HU180898B/hu unknown
- 1979-11-01 OA OA56928A patent/OA06368A/xx unknown
- 1979-11-01 JP JP14051279A patent/JPS5585523A/ja active Pending
- 1979-11-01 AR AR278737A patent/AR217576A1/es active

Also Published As

Publication number	Publication date
IT7926925A0 (it)	1979-10-30
ATA703979A (de)	1982-06-15
OA06368A (fr)	1981-07-31
BE879733A (fr)	1980-04-30
DE2943512A1 (de)	1980-05-14
FR2440193B1 (ja)	1983-04-29
DD146892A5 (de)	1981-03-11
GB2034327A (en)	1980-06-04
AT369652B (de)	1983-01-25
SE7909026L (sv)	1980-05-02
AR217576A1 (es)	1980-03-31
FI63521B (fi)	1983-03-31
FI793389A7 (fi)	1980-05-02
IT1162791B (it)	1987-04-01
CA1119094A (en)	1982-03-02
GB2034327B (en)	1982-11-17
AU5223179A (en)	1980-05-08
IL58541A (en)	1982-02-28
US4251437A (en)	1981-02-17
ES485550A1 (es)	1980-07-01
IL58541A0 (en)	1980-01-31
FI63521C (fi)	1983-07-11
AU522556B2 (en)	1982-06-10
FR2440193A1 (fr)	1980-05-30
JPS5585523A (en)	1980-06-27
HU180898B (en)	1983-05-30
NL7907984A (nl)	1980-05-06

Publication	Publication Date	Title
US4251437A (en)	1981-02-17	Process for producing an antihemophilic factor preparation from human blood plasma by irradiating with electromagnetic waves
KR101019188B1 (ko)	2011-03-03	불완전한 조직 복구를 치료하기 위한 조성물 및 최소 침습방법
EP0047216B1 (en)	1985-04-03	Method of selectively increasing yield and purity of certain cryoprecipitate proteins
JPH01143835A (ja)	1989-06-06	フィブリノゲンおよび因子ｘ３を含有する無菌の血漿−タンパク質を調整する方法
CH665125A5 (de)	1988-04-29	Verfahren zur inaktivierung der viren in einer ahf-angereicherten zusammensetzung.
Alaama et al.	2024	Development of leech extract as a therapeutic agent: A chronological review
Balbo et al.	2010	Platelet gel for the treatment of traumatic loss of finger substance
RU2112522C1 (ru)	1998-06-10	Состав для стабилизации плазмы крови, способ пастеризации плазмы и использование стабилизированной плазмы в терапии
US2162863A (en)	1939-06-20	Stable products shortening the bleeding period
Seibert et al.	1923	PROTEIN FEVERS: With Special Reference to Casein
JPH07206888A (ja)	1995-08-08	胎盤抽出物およびその製造方法
KR20150131864A (ko)	2015-11-25	어류의 정액 또는 정소로부터 분리된 디엔에이 단편 혼합물을 함유하는 회전근개 파열의 예방 또는 치료용 약학 조성물
DK143837B (da)	1981-10-19	Fremgangsmaade til fremstilling af et antihaemofilifaktorpraeparat ud fra dybfrosset humant blodplasma
RU2141326C1 (ru)	1999-11-20	Способ получения вытяжки из медицинских пиявок и средство с ее использованием
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US3504083A (en)	1970-03-31	Anti-plasmin means and method
US3504084A (en)	1970-03-31	Placental extract and method of producing the same from human placenta for use in relieving rheumatic diseases
WO2002043740A1 (en)	2002-06-06	Method for producing an immunotropic antiviral preparation
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