NO801267L - 2-aminoalkyl-5-pyridinoler, fremgangsmaate til deres fremstilling, farmasoeytiske preparater inneholdende disse forbindelser, samt deres terapeutiske anvendelse - Google Patents

2-aminoalkyl-5-pyridinoler, fremgangsmaate til deres fremstilling, farmasoeytiske preparater inneholdende disse forbindelser, samt deres terapeutiske anvendelse

Info

Publication number: NO801267L
Authority: NO; Norway
Prior art keywords: formula; compounds; preparation; xii; pyridinols
Prior art date: 1979-05-03

Application number

NO801267A

Other languages

English (en)

Other versions

NO154130B (no

NO154130C (no

Inventor

Renat Herbert Mizzoni

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1979-05-03

Filing date

1980-04-30

Publication date

1980-11-04

1980-04-30 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1980-11-04 Publication of NO801267L publication Critical patent/NO801267L/no

1986-04-14 Publication of NO154130B publication Critical patent/NO154130B/no

1986-07-23 Publication of NO154130C publication Critical patent/NO154130C/no

Links

150000001875 compounds Chemical class 0.000 title abstract 3
238000002360 preparation method Methods 0.000 title abstract 2
238000000034 method Methods 0.000 title 1
239000000825 pharmaceutical preparation Substances 0.000 title 1
230000001225 therapeutic effect Effects 0.000 title 1
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
150000002081 enamines Chemical class 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
125000006244 carboxylic acid protecting group Chemical group 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
150000002085 enols Chemical class 0.000 abstract 1
125000005842 heteroatom Chemical group 0.000 abstract 1
125000000623 heterocyclic group Chemical group 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
229910052757 nitrogen Chemical group 0.000 abstract 1
125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
229910052760 oxygen Inorganic materials 0.000 abstract 1
239000001301 oxygen Substances 0.000 abstract 1
229910052698 phosphorus Inorganic materials 0.000 abstract 1
239000011574 phosphorus Substances 0.000 abstract 1
239000000376 reactant Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Heart & Thoracic Surgery (AREA)
Pharmacology & Pharmacy (AREA)
Cardiology (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Cephalosporin Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicinal Preparation (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

NO801267A 1979-05-03 1980-04-30 Analogifremgangsmaate til fremstilling av terapeutisk aktive 2-aminoalkyl-5-pyridinoler. NO154130C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US3566879A	1979-05-03	1979-05-03

Publications (3)

Publication Number	Publication Date
NO801267L true NO801267L (no)	1980-11-04
NO154130B NO154130B (no)	1986-04-14
NO154130C NO154130C (no)	1986-07-23

Family

ID=21884070

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO801267A NO154130C (no)	1979-05-03	1980-04-30	Analogifremgangsmaate til fremstilling av terapeutisk aktive 2-aminoalkyl-5-pyridinoler.

Country Status (19)

Country	Link
EP (1)	EP0019739B1 (no)
JP (1)	JPS55149260A (no)
AT (1)	ATE8501T1 (no)
DD (1)	DD150461A5 (no)
DE (1)	DE3068577D1 (no)
DK (1)	DK157540C (no)
ES (1)	ES491055A0 (no)
FI (1)	FI70212C (no)
GB (1)	GB2050380B (no)
GR (1)	GR68206B (no)
HU (1)	HU181115B (no)
IE (1)	IE49712B1 (no)
IL (1)	IL59978A (no)
MA (1)	MA18964A1 (no)
NO (1)	NO154130C (no)
OA (1)	OA06528A (no)
PL (1)	PL223984A1 (no)
PT (1)	PT71176A (no)
ZW (1)	ZW9680A1 (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4746670A (en) *	1986-04-11	1988-05-24	Ciba-Geigy Corporation	Use of 2-aminoalkyl-5-pyridinols as nootropic agents and antidepressants
JP4732662B2 (ja) *	2000-04-06	2011-07-27	セイコーインスツル株式会社	電子時計の電池保持構造

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3952101A (en) *	1975-04-14	1976-04-20	Smithkline Corporation	α-Amino methyl-5-hydroxy-2-pyridinemethanols

1980
- 1980-04-30 DE DE8080102347T patent/DE3068577D1/de not_active Expired
- 1980-04-30 PT PT71176A patent/PT71176A/pt unknown
- 1980-04-30 FI FI801411A patent/FI70212C/fi not_active IP Right Cessation
- 1980-04-30 EP EP80102347A patent/EP0019739B1/de not_active Expired
- 1980-04-30 HU HU80801080A patent/HU181115B/hu not_active IP Right Cessation
- 1980-04-30 ES ES491055A patent/ES491055A0/es active Granted
- 1980-04-30 AT AT80102347T patent/ATE8501T1/de not_active IP Right Cessation
- 1980-04-30 ZW ZW96/80A patent/ZW9680A1/xx unknown
- 1980-04-30 NO NO801267A patent/NO154130C/no unknown
- 1980-05-01 IL IL59978A patent/IL59978A/xx unknown
- 1980-05-01 DK DK193180A patent/DK157540C/da not_active IP Right Cessation
- 1980-05-02 MA MA19024A patent/MA18964A1/fr unknown
- 1980-05-02 DD DD80220844A patent/DD150461A5/de not_active IP Right Cessation
- 1980-05-02 GR GR61845A patent/GR68206B/el unknown
- 1980-05-02 JP JP5800280A patent/JPS55149260A/ja active Granted
- 1980-05-02 GB GB8014705A patent/GB2050380B/en not_active Expired
- 1980-05-02 IE IE899/80A patent/IE49712B1/en not_active IP Right Cessation
- 1980-05-03 PL PL22398480A patent/PL223984A1/xx unknown
- 1980-05-03 OA OA57107A patent/OA06528A/xx unknown

Also Published As

Publication number	Publication date
DE3068577D1 (en)	1984-08-23
EP0019739B1 (de)	1984-07-18
ATE8501T1 (de)	1984-08-15
PT71176A (en)	1980-05-01
FI70212B (fi)	1986-02-28
JPS55149260A (en)	1980-11-20
FI70212C (fi)	1986-09-15
ZW9680A1 (en)	1980-11-26
DK157540C (da)	1990-06-11
JPS6365662B2 (no)	1988-12-16
EP0019739A1 (de)	1980-12-10
IE49712B1 (en)	1985-11-27
DD150461A5 (de)	1981-09-02
IL59978A (en)	1984-03-30
IL59978A0 (en)	1980-07-31
GB2050380A (en)	1981-01-07
HU181115B (en)	1983-06-28
NO154130B (no)	1986-04-14
MA18964A1 (fr)	1980-12-31
DK193180A (da)	1980-11-04
DK157540B (da)	1990-01-22
NO154130C (no)	1986-07-23
ES8104229A1 (es)	1981-04-01
IE800899L (en)	1980-11-03
ES491055A0 (es)	1981-04-01
PL223984A1 (no)	1981-02-13
GB2050380B (en)	1983-07-20
FI801411A7 (fi)	1980-11-04
GR68206B (no)	1981-11-10
OA06528A (fr)	1981-07-31

Publication	Publication Date	Title
DE3363244D1 (en)	1986-06-05	Compounds, process for their preparation and their use as pharmaceutical preparations
DK159148C (da)	1991-02-11	Analogifremgangsmaade til fremstilling af tranexamsyrederivater
ES2005746A6 (es)	1989-03-16	Un procedimiento para la preparacion de un haluro de piridinio.
DE3063189D1 (en)	1983-06-16	New derivatives of the 9-cis-6,6'-diapo-psi,psi-carotenedioic acid, preparation thereof and pharmaceutical compositions containing same
PT87277A (pt)	1988-05-01	Process for the preparation of new bicyclic compounds and pharmaceutical compositions comprising same
GB1434323A (en)	1976-05-05	N-acylated substituted piperazine or homopiperazine derivatives and processes for their preparation
ES8706610A1 (es)	1987-07-01	Proceso para preparar un derivado de aminoalcohol.
DE3068577D1 (en)	1984-08-23	2-aminoalkyl-5-pyridinoles, process for their preparation and pharmaceutical preparations containing them
ES8104309A1 (es)	1981-04-16	Procedimiento para preparar enaminas
DE3260303D1 (en)	1984-08-09	Process for the preparation of 4-quinolinones
GB1008849A (en)	1965-11-03	Basically substituted triazolidines, processes for their manufacture and pharmaceutical preparations containing them
ES8401059A1 (es)	1983-12-16	Procedimiento para la preparacion de fenoleteres biciclicos.
JPS557222A (en)	1980-01-19	Preparation of aletheine derivative
GB871235A (en)	1961-06-21	Novel substituted pyrrolidones and salts thereof and a process for the manufacture of same
DE3269453D1 (en)	1986-04-03	Process for the preparation of carboxylic acid anhydrides
ES451113A1 (es)	1977-11-16	Procedimiento para preparar derivados de acido oxamico.
ES478502A1 (es)	1980-07-01	Un procedimiento para la preparacion de nuevas n-(piridotie-nopirazol)amidas
ES473484A1 (es)	1979-11-01	Un procedimiento para la preparacion de nuevos eteres del acido clavulanico
DK145948C (da)	1983-09-26	Fremgangsmaade til fremstilling af sulfonimidoylxanthon-2-carboxylsyrederivater
ES8200668A1 (es)	1981-11-16	Un procedimiento para la preparacion de nuevos derivados de oxazolina y tiazolina