NO834792L - Dna-sekvenser, plasmider som inneholder slike sekvenser, samt fremgangsmaater for fremstilling av slike sekvenser og plasmider - Google Patents

Dna-sekvenser, plasmider som inneholder slike sekvenser, samt fremgangsmaater for fremstilling av slike sekvenser og plasmider

Info

Publication number: NO834792L
Authority: NO; Norway
Prior art keywords: sequences; procedures; preparing; plasmids containing; sequence
Prior art date: 1982-12-24

Application number

NO83834792A

Other languages

English (en)

Other versions

NO173742C (no

NO173742B (no

Inventor

Marc-Bruce Dworkin

Eva Dworkin-Rastl

Guenther Adolf

Peter Meindl

Peter Swetly

Rudolf Hauptmann

Norbert Hauel

Original Assignee

Boehringer Ingelheim Int

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-12-24

Filing date

1983-12-23

Publication date

1984-06-25

1983-12-23 Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int

1984-06-25 Publication of NO834792L publication Critical patent/NO834792L/no

1993-10-18 Publication of NO173742B publication Critical patent/NO173742B/no

1994-01-26 Publication of NO173742C publication Critical patent/NO173742C/no

Links

239000013612 plasmid Substances 0.000 title abstract 3
108091028043 Nucleic acid sequence Proteins 0.000 title 1
238000000034 method Methods 0.000 title 1
108090000623 proteins and genes Proteins 0.000 abstract 2
241000894006 Bacteria Species 0.000 abstract 1
102000014150 Interferons Human genes 0.000 abstract 1
108010050904 Interferons Proteins 0.000 abstract 1
QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 abstract 1
241000607715 Serratia marcescens Species 0.000 abstract 1
QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 abstract 1
238000003776 cleavage reaction Methods 0.000 abstract 1
239000013613 expression plasmid Substances 0.000 abstract 1
229940079322 interferon Drugs 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
230000007017 scission Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/56—IFN-alpha
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/66—General methods for inserting a gene into a vector to form a recombinant vector using cleavage and ligation; Use of non-functional linkers or adaptors, e.g. linkers containing the sequence for a restriction endonuclease
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- C12N15/68—Stabilisation of the vector

Landscapes

Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Biophysics (AREA)
Physics & Mathematics (AREA)
Microbiology (AREA)
Plant Pathology (AREA)
Toxicology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Saccharide Compounds (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)

NO834792A 1982-12-24 1983-12-23 Fremgangsmaate for fremstilling av et IFN- alpha-ekspresjonsplasmid og poly-peptid med IFN-aktivitet NO173742C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE19823247922 DE3247922A1 (de)	1982-12-24	1982-12-24	Dna-sequenzen, deren herstellung, diese sequenzen enthaltende plasmide und deren verwendung zur synthese eukaryotischer genprodukte in prokaryoten

Publications (3)

Publication Number	Publication Date
NO834792L true NO834792L (no)	1984-06-25
NO173742B NO173742B (no)	1993-10-18
NO173742C NO173742C (no)	1994-01-26

Family

ID=6181687

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO834792A NO173742C (no)	1982-12-24	1983-12-23	Fremgangsmaate for fremstilling av et IFN- alpha-ekspresjonsplasmid og poly-peptid med IFN-aktivitet

Country Status (19)

Country	Link
EP (1)	EP0115613B1 (no)
JP (2)	JPH088868B2 (no)
KR (1)	KR930005455B1 (no)
AT (1)	ATE62018T1 (no)
AU (1)	AU579991B2 (no)
DD (1)	DD216043A5 (no)
DE (2)	DE3247922A1 (no)
DK (1)	DK576983A (no)
ES (4)	ES528350A0 (no)
FI (1)	FI86991C (no)
GR (1)	GR78766B (no)
HU (1)	HU202277B (no)
IL (1)	IL70523A (no)
MX (1)	MX9202878A (no)
NO (1)	NO173742C (no)
NZ (1)	NZ206700A (no)
SU (2)	SU1366064A3 (no)
UA (1)	UA8035A1 (no)
ZA (1)	ZA839519B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE67786T1 (de) *	1984-08-01	1991-10-15	Boehringer Ingelheim Int	Neue genetische sequenzen, die durch sie codierten interferon-peptide vom typ i und diese sie produzierende organismen.
US6291662B1 (en)	1984-12-05	2001-09-18	Amgen Inc.	Recombinant methods for production of serine protease inhibitors and DNA sequences
IL77227A (en) *	1984-12-06	1992-08-18	Synergen Biolog Inc	Recombinant methods for production of serine protease inhibitors and methods for isolation of same
FI90990C (fi) *	1984-12-18	1994-04-25	Boehringer Ingelheim Int	Rekombinantti-DNA-molekyyli, transformoitu isäntäorganismi ja menetelmä interferonin valmistamiseksi
DK151585D0 (da) *	1985-04-03	1985-04-03	Nordisk Gentofte	Dna-sekvens
DK156072C (da) *	1985-04-03	1989-11-06	Nordisk Gentofte	Syntetisk dna-sekvens indeholdende et ribosombindingssted
DE3514113A1 (de) *	1985-04-19	1986-10-23	Hoechst Ag, 6230 Frankfurt	Veraenderung der dna-sequenz zwischen shine-dalgarno-sequenz und startcodon des trp-operons zur steigerung der proteinexpression
US4874703A (en) *	1985-08-26	1989-10-17	Eli Lilly And Company	Expression vectors for use in E. coli
DE3607835A1 (de) *	1986-03-10	1987-09-24	Boehringer Ingelheim Int	Hybridinterferone, deren verwendung als arzneimittel und als zwischenprodukte zur herstellung von antikoerpern und deren verwendung sowie verfahren zu ihrer herstellung
DE3642096A1 (de) *	1986-12-10	1988-06-16	Boehringer Ingelheim Int	Pferde-(gamma)-interferon
GB8813032D0 (en) *	1988-06-02	1988-07-06	Boehringer Ingelheim Int	Antiviral pharmaceutical composition
WO1990005186A1 (en) *	1988-11-04	1990-05-17	The Upjohn Company	Somatotropin expression using a serratia promoter
IL108584A (en) *	1994-02-07	2008-03-20	Yeda Res & Dev	Cloning of interferon -alpha/beta binding protein
EP0626448A3 (de) *	1993-05-26	1998-01-14	BOEHRINGER INGELHEIM INTERNATIONAL GmbH	Verfahren zur Herstellung und Reinigung von alpha-Interferon
US5531880A (en) *	1994-09-13	1996-07-02	Microelectronics And Computer Technology Corporation	Method for producing thin, uniform powder phosphor for display screens
FR2724665B1 (fr) *	1994-09-16	1996-12-20	Rhone Poulenc Rorer Sa	Procede de production de proteines recombinantes, plasmides et cellules modifiees

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA811368B (en) *	1980-03-24	1982-04-28	Genentech Inc	Bacterial polypedtide expression employing tryptophan promoter-operator
DE3176011D1 (en) *	1980-06-12	1987-04-23	Japan Found Cancer	Plasmid
ZA814375B (en) *	1980-07-01	1982-07-28	Hoffmann La Roche	Interferons and process for their preparation
IE52755B1 (en) *	1980-08-26	1988-02-17	Univ California	Bovine pre-growth and growth hormone
EP0062971B1 (en) *	1981-03-27	1990-03-07	Imperial Chemical Industries Plc	Genetically modified microorganisms
DE3220116A1 (de) *	1982-05-28	1983-12-01	Dr. Karl Thomae Gmbh, 7950 Biberach	Mikrobiologisch hergestellte (alpha)- und ss-interferone, dna-sequenzen, die fuer diese interferone codieren, mikroorganismen, die diese genetische information enthalten, und verfahren zu ihrer herstellung
DE3247923A1 (de) *	1982-12-24	1984-06-28	Dr. Karl Thomae Gmbh, 7950 Biberach	Neue oligonucleotide und verfahren zu ihrer herstellung

1982
- 1982-12-24 DE DE19823247922 patent/DE3247922A1/de not_active Withdrawn
1983
- 1983-12-02 GR GR73142A patent/GR78766B/el unknown
- 1983-12-14 DK DK576983A patent/DK576983A/da not_active Application Discontinuation
- 1983-12-20 EP EP83112812A patent/EP0115613B1/de not_active Expired - Lifetime
- 1983-12-20 DE DE8383112812T patent/DE3382233D1/de not_active Expired - Fee Related
- 1983-12-20 AT AT83112812T patent/ATE62018T1/de not_active IP Right Cessation
- 1983-12-21 FI FI834700A patent/FI86991C/fi not_active IP Right Cessation
- 1983-12-22 NZ NZ206700A patent/NZ206700A/en unknown
- 1983-12-22 ZA ZA839519A patent/ZA839519B/xx unknown
- 1983-12-22 DD DD83258476A patent/DD216043A5/de unknown
- 1983-12-22 HU HU834419A patent/HU202277B/hu not_active IP Right Cessation
- 1983-12-22 IL IL70523A patent/IL70523A/xx not_active IP Right Cessation
- 1983-12-23 SU SU833681952A patent/SU1366064A3/ru active
- 1983-12-23 KR KR1019830006147A patent/KR930005455B1/ko not_active Expired - Fee Related
- 1983-12-23 UA UA3681952A patent/UA8035A1/uk unknown
- 1983-12-23 JP JP58243626A patent/JPH088868B2/ja not_active Expired - Lifetime
- 1983-12-23 AU AU22832/83A patent/AU579991B2/en not_active Ceased
- 1983-12-23 ES ES528350A patent/ES528350A0/es active Granted
- 1983-12-23 NO NO834792A patent/NO173742C/no unknown
1984
- 1984-06-07 ES ES533214A patent/ES8504930A1/es not_active Expired
- 1984-06-07 ES ES533213A patent/ES8506090A1/es not_active Expired
- 1984-06-07 ES ES533197A patent/ES533197A0/es active Granted
1985
- 1985-08-02 SU SU853935004A patent/SU1417800A3/ru active
1992
- 1992-01-23 JP JP4009692A patent/JP2637328B2/ja not_active Expired - Lifetime
- 1992-06-15 MX MX9202878A patent/MX9202878A/es unknown

Also Published As

Publication number	Publication date
DD216043A5 (de)	1984-11-28
ES8503372A1 (es)	1985-02-16
JPS59162888A (ja)	1984-09-13
IL70523A (en)	1991-08-16
KR930005455B1 (ko)	1993-06-22
FI86991C (fi)	1992-11-10
ZA839519B (en)	1985-08-28
FI86991B (fi)	1992-07-31
ATE62018T1 (de)	1991-04-15
EP0115613B1 (de)	1991-03-27
FI834700L (fi)	1984-06-25
DE3247922A1 (de)	1984-06-28
GR78766B (no)	1984-10-02
DK576983D0 (da)	1983-12-14
DE3382233D1 (de)	1991-05-02
NO173742C (no)	1994-01-26
UA8035A1 (uk)	1995-12-26
NZ206700A (en)	1987-11-27
EP0115613A3 (en)	1986-07-23
ES533213A0 (es)	1985-06-16
NO173742B (no)	1993-10-18
AU579991B2 (en)	1988-12-22
JPH088868B2 (ja)	1996-01-31
ES533214A0 (es)	1985-04-16
MX9202878A (es)	1992-06-30
ES533197A0 (es)	1985-02-16
JP2637328B2 (ja)	1997-08-06
SU1417800A3 (ru)	1988-08-15
KR840007105A (ko)	1984-12-05
ES8501798A1 (es)	1984-12-01
SU1366064A3 (ru)	1988-01-07
ES528350A0 (es)	1984-12-01
HU202277B (en)	1991-02-28
JPH05214000A (ja)	1993-08-24
EP0115613A2 (de)	1984-08-15
FI834700A0 (fi)	1983-12-21
IL70523A0 (en)	1984-03-30
AU2283283A (en)	1984-06-28
DK576983A (da)	1984-06-25
ES8506090A1 (es)	1985-06-16
ES8504930A1 (es)	1985-04-16

Publication	Publication Date	Title
NO834792L (no)	1984-06-25	Dna-sekvenser, plasmider som inneholder slike sekvenser, samt fremgangsmaater for fremstilling av slike sekvenser og plasmider
Taniguchi et al.	1980	Expression of the human fibroblast interferon gene in Escherichia coli.
DK164742C (da)	1992-12-28	Dna-sekvens, der koder for ifn-alfa2(arg), pbr322-plasmid indeholdende en saadan dna-sekvens, fremgangsmaade til fremstilling af en klon indeholdende naevnte plasmid, og tilsvarende mikroorganisme, samt fremgangsmaader til fremstilling af henholdsvis ifn-alfa2(arg), naevnte mikroorganisme og naevnte dna-sekvens
GR861957B (en)	1986-11-25	Fusions proteins method for preparing them and their uses
SE8703539D0 (sv)	1987-09-14	Artificiell gen och proteinprodukt
AU2795989A (en)	1989-06-14	Production of gonorrheal pi proteins and vaccines
PT81025A (en)	1985-09-01	Process for the preparation of expression vectors containing lambeda pl promoter and engineered restriction site for convenient replacement of ribosomal binding site plasmids containing thevectors hosts containing the plasmids and related methods
DK0781341T3 (da)	2009-01-05	Fremgangsmåde til fremstilling af rekombinante proteiner, plasmider og modificerede celler
DK0652903T3 (da)	1998-03-30	Nyt humant rekombinant gammainterferon
DE3572843D1 (en)	1989-10-12	Site-specific proteolysis by renin
DE69018633D1 (de)	1995-05-18	Effizientes verfahren zur nachweisbaren expression nichtselektierbarer gene.
ATE87977T1 (de)	1993-04-15	Herstellung menschlichen somatomedins c.
NO910331L (no)	1991-07-30	Rekombinant plasmid, fremgangsmaate til dets fremstilling og anvendelse av plasmidet i produksjonen av proteiner.
ES8607393A1 (es)	1986-06-01	Utilizacion de una secuencia de adn para la expresion, asi como estructura de adn y vector de expresion con la secuen- cia de adn
ES8704209A1 (es)	1987-03-16	Un metodo para recuperar superoxido dismutasa eucariotica enzimaticamente activa o un analogo de la misma
BG52178B2 (en)	1998-06-30	Method for chemical synthesis and expression of the gene of human noncystein -interferon