NO841158L - Fremgangsmaate for fremstilling av 2-azetidin-4-substituerte forbindelser - Google Patents

Fremgangsmaate for fremstilling av 2-azetidin-4-substituerte forbindelser

Info

Publication number: NO841158L
Authority: NO; Norway
Prior art keywords: azetidin; procedure; preparation; substituted compounds; substituted
Prior art date: 1983-03-25

Application number

NO841158A

Other languages

English (en)

Other versions

NO158740C (no

NO158740B (no

Inventor

Toshinari Tamura

Hidenori Iwamoto

Makoto Yoshida

Minoru Yamamoto

Original Assignee

Yamanouchi Pharma Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-03-25

Filing date

1984-03-23

Publication date

1984-09-26

1983-03-25 Priority claimed from JP58048989A external-priority patent/JPS59225182A/ja

1983-11-25 Priority claimed from JP58221470A external-priority patent/JPS60115578A/ja

1983-11-25 Priority claimed from JP58221469A external-priority patent/JPS60115577A/ja

1984-03-23 Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd

1984-09-26 Publication of NO841158L publication Critical patent/NO841158L/no

1987-01-23 Priority to NO870289A priority Critical patent/NO167662C/no

1988-07-18 Publication of NO158740B publication Critical patent/NO158740B/no

1988-10-26 Publication of NO158740C publication Critical patent/NO158740C/no

Links

150000001875 compounds Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06147—Dipeptides with the first amino acid being heterocyclic and His-amino acid; Derivatives thereof

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO841158A 1983-03-25 1984-03-23 Analogifremgangsmaate ved fremstilling av terapeutisk aktive 4-substituerte 2-azetidinonforbindelser. NO158740C (no)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
NO870289A NO167662C (no)	1983-03-25	1987-01-23	4-substituerte-2-azetidinonforbindelser.

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
JP58048989A JPS59225182A (ja)	1983-03-25	1983-03-25	２−アゼチジノン−４−カルボン酸の誘導体
JP58221470A JPS60115578A (ja)	1983-11-25	1983-11-25	２−アゼチジノン−４−置換化合物
JP58221469A JPS60115577A (ja)	1983-11-25	1983-11-25	２−アゼチジノン−４−置換体

Publications (3)

Publication Number	Publication Date
NO841158L true NO841158L (no)	1984-09-26
NO158740B NO158740B (no)	1988-07-18
NO158740C NO158740C (no)	1988-10-26

Family

ID=27293483

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO841158A NO158740C (no)	1983-03-25	1984-03-23	Analogifremgangsmaate ved fremstilling av terapeutisk aktive 4-substituerte 2-azetidinonforbindelser.

Country Status (8)

Country	Link
US (3)	US4564609A (no)
EP (1)	EP0123444B1 (no)
KR (3)	KR870000357B1 (no)
CA (1)	CA1256650A (no)
DE (1)	DE3476399D1 (no)
DK (1)	DK164684A (no)
ES (4)	ES530960A0 (no)
NO (1)	NO158740C (no)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4719207A (en) *	1984-06-25	1988-01-12	Yamanouchi Pharmaceutical Co., Ltd.	CNS active substituted azetidinone compounds
JPS6253994A (ja)	1985-05-09	1987-03-09	Yamanouchi Pharmaceut Co Ltd	１−置換シリル−４−オキソ−２−アゼチジンカルボン酸低級アルキルエステル
ZA868957B (en) *	1985-12-06	1987-07-29	Yamanouchi Pharma Co Ltd	Crystals of nalpha-(((s)-4-oxo-2-azetidinyl)carbonyl)-l-histidyl-l-prolinamide and process for producing the crystals
US5686420A (en) *	1987-06-05	1997-11-11	Georgetown University	Thyrotropin-releasing hormone analogs and method of use
US5151497A (en) *	1989-02-21	1992-09-29	Japan Tobacco Inc.	Histidyl peptide derivatives
DK437289D0 (da) *	1989-09-04	1989-09-04	Hans Bundgaard	Prodrug derivatives of thyrotropin-releasing hormone (trh)
IT1249728B (it) *	1991-11-06	1995-03-09	Sigma Tau Ind Farmaceuti	Derivati delle prolinammide quali attivatori della memoria e dei processi di apprendimento e composizioni farmaceutiche che li contengono
CA2288986A1 (en) *	1997-05-09	1998-11-12	Smithkline Beecham Corporation	Beta-lactam inhibitors of coa-it
US20020151502A1 (en) *	1997-10-09	2002-10-17	Albert Sattin	Tri-peptides for neurological and neurobehavior applications
US7202279B1 (en) *	1998-02-11	2007-04-10	Georgetown University	Cyclic dipeptides and azetidinone compounds and their use in treating CNS injury and neurodegenerative disorders
JP4812225B2 (ja) *	2000-07-11	2011-11-09	塩野義製薬株式会社	生理活性ペプチド含有腸溶性製剤
KR20050105290A (ko)	2000-08-31	2005-11-03	시오노기세이야쿠가부시키가이샤	파킨슨씨병 치료제
US6982251B2 (en) *	2000-12-20	2006-01-03	Schering Corporation	Substituted 2-azetidinones useful as hypocholesterolemic agents
PL364178A1 (en) *	2001-01-26	2004-12-13	Schering Corporation	Combinations of sterol absorption inhibitor(s) with blood modifier(s) for treating vascular conditions
AU2002241956A1 (en) *	2001-01-26	2002-08-06	Schering Corporation	Combinations of bile acid sequestrant(s) and sterol absorption inhibitor(s) and treatments for vascular indications
US20020183305A1 (en) *	2001-01-26	2002-12-05	Schering Corporation	Combinations of nicotinic acid and derivatives thereof and sterol absorption inhibitor(s) and treatments for vascular indications
IL156585A0 (en) *	2001-01-26	2004-01-04	Schering Corp	Combinations of sterol absorption inhibitor(s) with cardiovascular agent(s) for the treatment of vascular conditions
HU230253B1 (hu) *	2001-01-26	2015-11-30	Merck Sharp & Dohme Corp	Peroxiszóma proliferátor-aktivált receptor (PPAR) aktivátor(ok) és szterin-abszorpció inhibitor(ok) kombinációi és alkalmazásuk vaszkuláris indikációk kezelésére
US20060287254A1 (en) *	2001-01-26	2006-12-21	Schering Corporation	Use of substituted azetidinone compounds for the treatment of sitosterolemia
US7071181B2 (en) *	2001-01-26	2006-07-04	Schering Corporation	Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
DK1355644T3 (da) *	2001-01-26	2006-10-23	Schering Corp	Anvendelse af substituerede azetidinonforbindelser til behandling af sitosterolæmi
JP2004532868A (ja) *	2001-05-25	2004-10-28	シェーリング　コーポレイション	アルツハイマー病の処置におけるアゼチジノン置換誘導体の使用
US20030119808A1 (en) *	2001-09-21	2003-06-26	Schering Corporation	Methods of treating or preventing cardiovascular conditions while preventing or minimizing muscular degeneration side effects
US7056906B2 (en) *	2001-09-21	2006-06-06	Schering Corporation	Combinations of hormone replacement therapy composition(s) and sterol absorption inhibitor(s) and treatments for vascular conditions in post-menopausal women
AU2002335770B2 (en) *	2001-09-21	2005-08-18	Merck Sharp & Dohme Corp.	Methods for treating or preventing vascular inflammation using sterol absorption inhibitor(s)
US7053080B2 (en) *	2001-09-21	2006-05-30	Schering Corporation	Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
JP2005504091A (ja) *	2001-09-21	2005-02-10	シェーリング　コーポレイション	ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置
WO2004043457A1 (en) *	2002-11-06	2004-05-27	Schering Corporation	Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
US7459442B2 (en) *	2003-03-07	2008-12-02	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP4589919B2 (ja) *	2003-03-07	2010-12-01	シェーリングコーポレイション	高コレステロール血症の処置のための、置換アゼチジノン化合物、これらの処方物および使用
CA2517571C (en) *	2003-03-07	2011-07-05	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP2006519869A (ja) *	2003-03-07	2006-08-31	シェーリング　コーポレイション	置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用
EP1680189A2 (en) *	2003-11-05	2006-07-19	Schering Corporation	Combinations of lipid modulating agents and substituted azetidinones and treatments for vascular conditions
US7462595B2 (en) *	2004-09-17	2008-12-09	Prange Jr Arthur Jergen	Methods for treating cancer-related fatigue
KR101137503B1 (ko) *	2009-07-14	2012-04-20	웰이앤씨 주식회사	고분자 고체 지지체를 이용한 히스티딜-프롤린아미드 유도체의 제조 방법
CN105452198B (zh) *	2013-08-16	2019-09-03	洛斯阿拉莫斯国家安全股份有限公司	用于改善植物性能的化合物和方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3959248A (en) *	1974-04-03	1976-05-25	Merck & Co., Inc.	Analogs of thyrotropin-releasing hormone
GB1523598A (en) *	1975-03-08	1978-09-06	Reckitt & Colmann Prod Ltd	Tripeptides
US4271164A (en) *	1979-04-16	1981-06-02	Warner-Lambert Company	6-Substituted-arylpyrido[2,3-d]pyrimidin-7-amines and derivatives
HU180926B (en) *	1979-06-28	1983-05-30	Richter Gedeon Vegyeszet	Process for preparing trh analogues,tripeptide amides infectives on the central nerve sysrhem
US4328134A (en) *	1980-05-06	1982-05-04	Schally Andrew Victor	Anorexigenic peptides
US4426378A (en) *	1981-04-09	1984-01-17	The United States Of America As Represented By The Secretary Of The Army	Thyrotropin releasing hormone in therapy of shock and as a central nervous system stimulant

1984
- 1984-03-15 CA CA000449641A patent/CA1256650A/en not_active Expired
- 1984-03-23 DK DK164684A patent/DK164684A/da not_active Application Discontinuation
- 1984-03-23 ES ES530960A patent/ES530960A0/es active Granted
- 1984-03-23 NO NO841158A patent/NO158740C/no unknown
- 1984-03-23 US US06/592,866 patent/US4564609A/en not_active Expired - Fee Related
- 1984-03-23 KR KR1019840001506A patent/KR870000357B1/ko not_active Expired
- 1984-03-26 DE DE8484302016T patent/DE3476399D1/de not_active Expired
- 1984-03-26 EP EP84302016A patent/EP0123444B1/en not_active Expired
1985
- 1985-06-14 ES ES85544234A patent/ES8604209A1/es not_active Expired
- 1985-06-14 ES ES544235A patent/ES8604208A1/es not_active Expired
- 1985-06-14 ES ES544236A patent/ES8604136A1/es not_active Expired
- 1985-10-07 US US06/785,169 patent/US4636567A/en not_active Expired - Fee Related
- 1985-10-07 US US06/785,168 patent/US4610821A/en not_active Expired - Fee Related
1987
- 1987-01-20 KR KR1019870000408A patent/KR890002104B1/ko not_active Expired
- 1987-01-20 KR KR1019870000409A patent/KR890002105B1/ko not_active Expired

Also Published As

Publication number	Publication date
CA1256650A (en)	1989-06-27
EP0123444B1 (en)	1989-01-25
US4564609A (en)	1986-01-14
KR890002104B1 (ko)	1989-06-19
ES544235A0 (es)	1986-01-16
NO158740C (no)	1988-10-26
KR880009549A (ko)	1988-09-15
KR870000357B1 (ko)	1987-03-05
ES8604208A1 (es)	1986-01-16
EP0123444A1 (en)	1984-10-31
US4636567A (en)	1987-01-13
DK164684A (da)	1984-09-26
DK164684D0 (da)	1984-03-23
ES8600279A1 (es)	1985-10-01
NO158740B (no)	1988-07-18
ES8604209A1 (es)	1986-01-16
KR890002105B1 (ko)	1989-06-19
DE3476399D1 (en)	1989-03-02
ES530960A0 (es)	1985-10-01
ES544236A0 (es)	1986-01-16
US4610821A (en)	1986-09-09
KR840008021A (ko)	1984-12-12
ES544234A0 (es)	1986-01-16
ES8604136A1 (es)	1986-01-16
KR880009550A (ko)	1988-09-15

Publication	Publication Date	Title
NO841158L (no)	1984-09-26	Fremgangsmaate for fremstilling av 2-azetidin-4-substituerte forbindelser
NO843956L (no)	1985-04-09	Fremgangsmaate for fremstilling av karboksyalkenamido-cefalosporiner
RO90861A (ro)	1987-04-30	Procedeu pentru prepararea etielnglicolului
NO833705L (no)	1984-04-16	Fremgangsmaate for fremstilling av fenyl-piperidin-propanol-forbindelser.
NO851524L (no)	1985-10-18	Fremgangsmaate for fremstilling av fenetanolamin-forbindelser
NO844710L (no)	1985-05-29	Fremgangsmaate for fremstilling av hoeyrent protein
NO844388L (no)	1985-06-24	Fremgangsmaate for fremstilling av aminoeteralkoholer
RO86213A (ro)	1985-03-15	Procedeu pentru prepararea izobutenei
NO845162L (no)	1985-07-01	Fremgangsmaate for fremstilling av alkalimetallsalter
NO814065L (no)	1982-06-01	Fremgansmaate for fremstilling av imidazolylfenylamidiner
NO844631L (no)	1985-05-28	Fremgangsmaate for fremstilling av tremasse
NO845207L (no)	1985-06-24	Fremgangsmaate for fremstilling av diaminopolyalkenyletere
NO843055L (no)	1985-01-30	Fremgangsmaate ved fremstilling av cephalosporinderivater
NO170019C (no)	1992-09-02	Fremgangsmaate for fremstilling av deglucoteicoplanin (antibiotikum l 17392)
NO842868L (no)	1985-01-15	Framgangsmaate for framstilling av alkoholer
NO169126C (no)	1992-05-13	Fremgangsmaate for fremstilling av n-formyl-alfa-aspartyl-fenylalanin
NO823637L (no)	1983-05-04	Fremgangsmaate for fremstilling av eburnamoninderivater
FI840478A0 (fi)	1984-02-06	Foerfarande foer framstaellning av blodtryckssaenkande n-piperazinylalkanoylanilider
TR22146A (tr)	1986-08-17	Difloropiridin bilesiklerinin hazirlanmasi
NO832830L (no)	1984-02-07	Fremgangsmaate for fremstilling av alfa-arylalkansyrer
NO833531L (no)	1984-04-02	Fremgangsmaate for fremstilling av 7-substituerte-3-vinyl-3-cefem-forbindelser
NO172547C (no)	1993-08-04	Fremgangsmaate til fremstilling av nalfa-acetyl-eglin b og -c
NO840865L (no)	1984-09-10	Fremgangsmaate til fremstilling av carbapenemderivater
NO830176L (no)	1983-07-29	Fremgangsmaate for fremstilling av ultrarent toriumfluorid
NO813814L (no)	1982-05-14	Fremgangsmaate for fremstilling av monoalkyletere av hydrokinonforbindelser