NO842534L - Fremgangsmaate ved fremstilling av nye prostacyclinderivater - Google Patents

Fremgangsmaate ved fremstilling av nye prostacyclinderivater

Info

Publication number
NO842534L
NO842534L NO842534A NO842534A NO842534L NO 842534 L NO842534 L NO 842534L NO 842534 A NO842534 A NO 842534A NO 842534 A NO842534 A NO 842534A NO 842534 L NO842534 L NO 842534L
Authority
NO
Norway
Prior art keywords
group
procedure
preparation
new
see diagramm
Prior art date
Application number
NO842534A
Other languages
English (en)
Other versions
NO158874B (no
NO158874C (no
Inventor
Werner Skuballa
Helmut Dahl
Bernd Raduechel
Helmut Vorbrueggen
Olaf Loge
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO842534L publication Critical patent/NO842534L/no
Publication of NO158874B publication Critical patent/NO158874B/no
Publication of NO158874C publication Critical patent/NO158874C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/41—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/02—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 2
    • C07D317/06—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 2 condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Photolithography (AREA)
  • Cosmetics (AREA)
  • Epoxy Compounds (AREA)
  • Fats And Perfumes (AREA)
  • Liquid Developers In Electrophotography (AREA)
  • Control Of Transmission Device (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO842534A 1983-06-23 1984-06-22 Analogifremgangsmaate ved fremstilling av nye, terapeutiskaktive prostacyclinderivater. NO158874C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3322893A DE3322893A1 (de) 1983-06-23 1983-06-23 Neue prostacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel

Publications (3)

Publication Number Publication Date
NO842534L true NO842534L (no) 1984-12-27
NO158874B NO158874B (no) 1988-08-01
NO158874C NO158874C (no) 1988-11-09

Family

ID=6202360

Family Applications (1)

Application Number Title Priority Date Filing Date
NO842534A NO158874C (no) 1983-06-23 1984-06-22 Analogifremgangsmaate ved fremstilling av nye, terapeutiskaktive prostacyclinderivater.

Country Status (20)

Country Link
US (1) US4894391A (no)
EP (1) EP0130142B1 (no)
JP (1) JPS6036477A (no)
AT (1) ATE43589T1 (no)
AU (1) AU562506B2 (no)
CA (1) CA1252088A (no)
CS (1) CS243491B2 (no)
DD (1) DD220204A5 (no)
DE (2) DE3322893A1 (no)
DK (1) DK299584A (no)
ES (1) ES8503348A1 (no)
FI (1) FI82040C (no)
GR (1) GR82122B (no)
HU (1) HU191150B (no)
IL (1) IL72198A (no)
NO (1) NO158874C (no)
NZ (1) NZ208623A (no)
PH (1) PH22431A (no)
SU (1) SU1450739A3 (no)
ZA (1) ZA844766B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63174984A (ja) * 1987-01-16 1988-07-19 Nissan Chem Ind Ltd シアノプロスタサイクリン類の合成法
ATE122563T1 (de) * 1989-07-27 1995-06-15 Ueno Seiyaku Oyo Kenkyujo Kk Verwendung von 15-keto-prostansäure-derivaten zur herstellung eines medikaments für die verbesserung der ausscheidung des kaliumions.
EP0925787A4 (en) * 1997-02-27 1999-12-01 Toray Industries DRUGS TO IMPROVE PULMONARY CIRCULATION
US7008307B2 (en) * 2003-09-02 2006-03-07 Wolff Industries Apparatus for sharpening a circular blade
US20080242713A1 (en) * 2007-03-28 2008-10-02 Bayer Schering Pharma Aktiengesellschaft Novel 5-cyano-prostacyclin derivatives as agents for the treatment of autoimmune diseases
US7776896B2 (en) * 2007-03-28 2010-08-17 Bayer Schering Pharma Aktiengesellschaft 5-cyano-prostacyclin derivatives as agents for the treatment of influenza a viral infection
EP1975163A1 (en) * 2007-03-28 2008-10-01 Bayer Schering Pharma Aktiengesellschaft Novel 5-cyano-prostacyclin derivatives and their use as agents for the treatment of influenza a viral infection
EP1988087A1 (en) * 2007-03-28 2008-11-05 Bayer Schering Pharma Aktiengesellschaft Novel 5-cyano-prostacyclin derivatives and their use as agents for the treatment of autoimmune diseases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3953435A (en) * 1974-01-10 1976-04-27 Ono Pharmaceutical Company Aldehyde derivatives of prostaglandins
DE2753244A1 (de) * 1977-11-25 1979-06-07 Schering Ag Neue prostacyclinderivate und verfahren zu ihrer herstellung
US4565827A (en) * 1980-10-27 1986-01-21 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara R.T. 7-Substituted PGI2 -derivatives and pharmaceutical compositions containing them
DE3041601A1 (de) * 1980-10-31 1982-06-16 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue prostacyclinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
US4475681A (en) * 1982-05-24 1984-10-09 The Micromanipulator Co., Inc. Bonder apparatus

Also Published As

Publication number Publication date
ATE43589T1 (de) 1989-06-15
IL72198A0 (en) 1984-10-31
FI842524A7 (fi) 1984-12-24
ES533642A0 (es) 1985-03-01
EP0130142A1 (de) 1985-01-02
FI842524A0 (fi) 1984-06-21
AU562506B2 (en) 1987-06-11
JPS6036477A (ja) 1985-02-25
DE3478435D1 (en) 1989-07-06
FI82040C (fi) 1991-01-10
NO158874B (no) 1988-08-01
HUT34180A (en) 1985-02-28
GR82122B (no) 1984-12-13
FI82040B (fi) 1990-09-28
DD220204A5 (de) 1985-03-27
CS474184A2 (en) 1985-08-15
EP0130142B1 (de) 1989-05-31
CA1252088A (en) 1989-04-04
NZ208623A (en) 1987-11-27
CS243491B2 (en) 1986-06-12
DE3322893A1 (de) 1985-01-03
SU1450739A3 (ru) 1989-01-07
US4894391A (en) 1990-01-16
AU2978684A (en) 1985-01-03
NO158874C (no) 1988-11-09
IL72198A (en) 1987-09-16
ES8503348A1 (es) 1985-03-01
HU191150B (en) 1987-01-28
ZA844766B (en) 1985-02-27
DK299584D0 (da) 1984-06-19
DK299584A (da) 1984-12-24
PH22431A (en) 1988-09-12

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