NO844291L - Griseolsyrederivater - Google Patents

Griseolsyrederivater

Info

Publication number: NO844291L
Authority: NO; Norway
Prior art keywords: griseolic acid; griseolic; pde; diluents; formulated
Prior art date: 1983-10-28

Application number

NO844291A

Other languages

English (en)

Other versions

NO164904C (no

NO164904B (no

Inventor

Masakatsu Kaneko

Misako Kimura

Yoshinobu Murofushi

Mitsuo Yamazaki

Nobuyoshi Iwata

Fumio Nakagawa

Original Assignee

Sankyo Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-10-28

Filing date

1984-10-29

Publication date

1985-04-29

1984-10-29 Application filed by Sankyo Co filed Critical Sankyo Co

1985-04-29 Publication of NO844291L publication Critical patent/NO844291L/no

1990-08-20 Publication of NO164904B publication Critical patent/NO164904B/no

1990-11-28 Publication of NO164904C publication Critical patent/NO164904C/no

Links

IAPZXUKYTCQQFE-QZKDJMESSA-N (2r,3r,3as,5s)-2-(6-aminopurin-9-yl)-5-[carboxy(hydroxy)methyl]-3-hydroxy-3,3a-dihydro-2h-furo[3,2-b]furan-5-carboxylic acid Chemical compound NC1=NC=NC2=C1N=CN2[C@H]1[C@H](O)[C@@H]2O[C@](C(O)=O)(C(O)C(O)=O)C=C2O1 IAPZXUKYTCQQFE-QZKDJMESSA-N 0.000 title abstract 3
IAPZXUKYTCQQFE-UHFFFAOYSA-N Griseolic acid Natural products NC1=NC=NC2=C1N=CN2C1C(O)C2OC(C(O)=O)(C(O)C(O)=O)C=C2O1 IAPZXUKYTCQQFE-UHFFFAOYSA-N 0.000 title abstract 2
ZOOGRGPOEVQQDX-UUOKFMHZSA-N 3',5'-cyclic GMP Chemical compound C([C@H]1O2)OP(O)(=O)O[C@H]1[C@@H](O)[C@@H]2N1C(N=C(NC2=O)N)=C2N=C1 ZOOGRGPOEVQQDX-UUOKFMHZSA-N 0.000 abstract 1
239000000969 carrier Substances 0.000 abstract 1
239000003085 diluting agent Substances 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
230000001988 toxicity Effects 0.000 abstract 1
231100000419 toxicity Toxicity 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
- A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Hospice & Palliative Care (AREA)
Hematology (AREA)
Psychiatry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Organic Insulating Materials (AREA)
Fats And Perfumes (AREA)
Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

NO844291A 1983-10-28 1984-10-29 Analogifremgangsmaate til fremstilling av terapeutisk aktive griseolsyrederivater. NO164904C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP58202362A JPS6094992A (ja)	1983-10-28	1983-10-28	グリゼオ−ル酸誘導体

Publications (3)

Publication Number	Publication Date
NO844291L true NO844291L (no)	1985-04-29
NO164904B NO164904B (no)	1990-08-20
NO164904C NO164904C (no)	1990-11-28

Family

ID=16456245

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO844291A NO164904C (no)	1983-10-28	1984-10-29	Analogifremgangsmaate til fremstilling av terapeutisk aktive griseolsyrederivater.

Country Status (12)

Country	Link
US (1)	US4634706A (no)
EP (1)	EP0143557B1 (no)
JP (1)	JPS6094992A (no)
KR (1)	KR930000165B1 (no)
AT (1)	ATE39357T1 (no)
CA (1)	CA1267408A (no)
DE (1)	DE3475714D1 (no)
DK (1)	DK166323C (no)
ES (4)	ES8604737A1 (no)
FI (1)	FI81357C (no)
NO (1)	NO164904C (no)
SU (4)	SU1600632A3 (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4783532A (en) *	1983-10-28	1988-11-08	Sankyo Company Limited	Process for preparing griseolic acid derivatives
IT1196261B (it) *	1984-09-20	1988-11-16	Pierrel Spa	Derivati nucleosidici e purinici 8-sostituiti
EP0318060B1 (en) *	1985-04-19	1995-10-25	Sankyo Company Limited	Griseolic acid derivatives, their preparation and their use
DK167878B1 (da) *	1985-04-19	1993-12-27	Sankyo Co	Griseolsyrederivater
JPH0631307B2 (ja) *	1985-04-27	1994-04-27	三共株式会社	グリゼオ−ル酸誘導体の製法
US5214048A (en) *	1987-05-19	1993-05-25	Nippon Kayaku Kabushiki Kaisha	Oxetanocins
JPH0774229B2 (ja) *	1987-12-02	1995-08-09	三共株式会社	グリゼオール酸モノエステル誘導体
US5091431A (en) *	1988-02-08	1992-02-25	Schering Corporation	Phosphodiesterase inhibitors
JPH0689020B2 (ja) *	1988-06-30	1994-11-09	三共株式会社	グリゼオール酸のモノエステル誘導体
US4971972A (en) *	1989-03-23	1990-11-20	Schering Corporation	Phosphodiesterase inhibitors having an optionally substituted purine derivative portion and a benzo- or cyclopenta-furan portion
JP3645580B2 (ja) *	1993-10-22	2005-05-11	株式会社フジモト・ブラザーズ	グルコースエステル誘導体を含有する脳代謝改善剤
US6291516B1 (en) *	1999-01-13	2001-09-18	Curis, Inc.	Regulators of the hedgehog pathway, compositions and uses related thereto
EP1312363A1 (en) *	2001-09-28	2003-05-21	Pfizer Products Inc.	Methods of treatment and kits comprising a growth hormone secretagogue
US7342884B2 (en) *	2002-03-13	2008-03-11	Harmonic, Inc.	Method and apparatus for one directional communications in bidirectional communications channel
WO2011081915A2 (en) *	2009-12-15	2011-07-07	Cebix Inc.	Methods for treating erectile dysfunction in patients with insulin-dependent diabetes
US12434171B2 (en) *	2021-02-19	2025-10-07	Anhui Jinhe Industrial Co., Ltd.	Production apparatus and production method of sucrose-6-ester

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3862189A (en) *	1973-08-14	1975-01-21	Warner Lambert Co	Aralkyl-substituted purines and pyrimidines as antianginal bronchodilator agents
GB1523865A (en) *	1974-09-02	1978-09-06	Wellcome Found	Purine compunds and salts thereof
US4138562A (en) *	1977-02-09	1979-02-06	The Regents Of The University Of Minnesota	Adenosine deaminase resistant antiviral purine nucleosides and method of preparation
JPS5668695A (en) *	1979-11-10	1981-06-09	Sankyo Co Ltd	Enzyme inhibitor griseolic acid and its preparation
DE3028273A1 (de) *	1980-07-25	1982-02-25	Fa. Dr. Willmar Schwabe, 7500 Karlsruhe	Durch purinbasen substituierte 1.4;3.6-dianhydro-hexit-nitrate
JPS60246396A (ja) *	1984-05-22	1985-12-06	Sankyo Co Ltd	酵素阻害物質ジヒドロデスオキシグリゼオ−ル酸及びその塩類

1983
- 1983-10-28 JP JP58202362A patent/JPS6094992A/ja active Granted
1984
- 1984-10-25 US US06/664,866 patent/US4634706A/en not_active Expired - Fee Related
- 1984-10-26 ES ES537154A patent/ES8604737A1/es not_active Expired
- 1984-10-26 FI FI844225A patent/FI81357C/fi not_active IP Right Cessation
- 1984-10-26 SU SU843808501A patent/SU1600632A3/ru active
- 1984-10-26 DK DK513384A patent/DK166323C/da not_active IP Right Cessation
- 1984-10-27 KR KR1019840006706A patent/KR930000165B1/ko not_active Expired - Fee Related
- 1984-10-29 AT AT84307436T patent/ATE39357T1/de not_active IP Right Cessation
- 1984-10-29 DE DE8484307436T patent/DE3475714D1/de not_active Expired
- 1984-10-29 CA CA000466527A patent/CA1267408A/en not_active Expired - Fee Related
- 1984-10-29 NO NO844291A patent/NO164904C/no unknown
- 1984-10-29 EP EP84307436A patent/EP0143557B1/en not_active Expired
1985
- 1985-09-25 ES ES547292A patent/ES8604981A1/es not_active Expired
- 1985-09-25 ES ES547291A patent/ES8701193A1/es not_active Expired
- 1985-09-26 ES ES547347A patent/ES8700673A1/es not_active Expired
- 1985-10-03 SU SU853962054A patent/SU1468422A3/ru active
- 1985-10-03 SU SU853960265A patent/SU1604158A3/ru active
- 1985-10-03 SU SU853961256A patent/SU1468421A3/ru active

Also Published As

Publication number	Publication date
ES547291A0 (es)	1986-11-16
ES8701193A1 (es)	1986-11-16
ATE39357T1 (de)	1989-01-15
ES537154A0 (es)	1985-12-01
FI844225L (fi)	1985-04-29
ES8604737A1 (es)	1985-12-01
DK166323C (da)	1993-08-30
DK166323B (da)	1993-04-05
EP0143557B1 (en)	1988-12-21
JPH0432837B2 (no)	1992-06-01
US4634706A (en)	1987-01-06
ES547347A0 (es)	1986-10-16
KR850003415A (ko)	1985-06-17
NO164904C (no)	1990-11-28
SU1604158A3 (ru)	1990-10-30
JPS6094992A (ja)	1985-05-28
SU1468422A3 (ru)	1989-03-23
DK513384A (da)	1985-04-29
DE3475714D1 (en)	1989-01-26
SU1468421A3 (ru)	1989-03-23
CA1267408A (en)	1990-04-03
ES8604981A1 (es)	1986-02-16
FI81357B (fi)	1990-06-29
DK513384D0 (da)	1984-10-26
FI844225A0 (fi)	1984-10-26
KR930000165B1 (ko)	1993-01-11
EP0143557A3 (en)	1985-07-03
ES8700673A1 (es)	1986-10-16
ES547292A0 (es)	1986-02-16
FI81357C (fi)	1990-10-10
SU1600632A3 (ru)	1990-10-15
EP0143557A2 (en)	1985-06-05
NO164904B (no)	1990-08-20

Publication	Publication Date	Title
FI844225L (fi)	1985-04-29	Griseolinsyraderivat och deras anvaendning.
DK0430045T3 (da)	1995-07-17	Ascorbinsyretocopherylphosphatdiestere til hæmning af Maillards reaktion
CU22305A3 (es)	1995-01-31	Procedimiento para la preparacion de un derivado de aminoacidos
ES2059408T3 (es)	1994-11-16	Un proceso para la preparacion de un compuesto.
ATE175671T1 (de)	1999-01-15	Heterocyclylcarbonylsubstituierte benzofuranyl- und -thiophenylalkancarbonsäurederivate
ZA911728B (en)	1992-11-25	Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors
FI920430A0 (fi)	1992-01-30	Benzyloxifenylderivator.
YU46998B (sh)	1994-11-15	Postupak za dobijanje derivata cefema i medjuproizvoda za iste
SE8107273L (sv)	1982-06-06	2-oxoazetidinderivat, sett att framstella democh anvendning derav
DE68903092D1 (de)	1992-11-05	Laktamimide in der behandlung arzneiresistenter protozoeninjektionen.
IT1224405B (it)	1990-10-04	Composti attivi sul sistema cardiovascolare
NO890046D0 (no)	1989-01-05	Disubstituerte pyridiner.
ATE129501T1 (de)	1995-11-15	Griseolsäurederivate, ihre herstellung und ihre verwendung.
DK578887D0 (da)	1987-11-04	Antihypertensiva
NO20001758L (no)	2000-06-05	FremgangsmÕter og blandinger for behandling av leddgikt
DE3570249D1 (en)	1989-06-22	Enzyme-inhibitory griseolic acid derivatives, and their use
DE3668888D1 (de)	1990-03-15	Ein imidazolidintrion-derivat oder ein seiner pharmazeutisch akzeptierbaren salze enthaltende pharmazeutische zusammenstellung.
SE8802193L (sv)	1989-02-08	Utvaertes anvaendbar, antiviral farmaceutisk komposition som ackumuleras i huden samt foerfarande foer framsttaellning av densamma
ES2160093A1 (es)	2001-10-16	Derivados del acido p-hidroxifenil propionico como agentes antiproliferativos.
ES8105259A1 (es)	1981-05-16	Un procedimiento para la preparacion de nuevas sales de clorhexidina
IT1215340B (it)	1990-02-08	Derivati di esteri dell'acido immidazol-1-il-carbossilico, procedimenti per la loro preparazione e composizioni fungicide che contengono il derivato come componente attivo.
GB1470747A (en)	1977-04-21	Pyridazine derivative
JPS5233662A (en)	1977-03-14	Preparation of n2-naphthalenesulfonyl-alginamides and acid addition sa lts thereof
GEP19980890B (en)	1998-04-08	Derivatives of N1-(1,2-Cis-halogeno¬-cyclopropyl) Substituted Pyridonecarbonic Acid
ATE48611T1 (de)	1989-12-15	Griseolinsaeurederivate, ihre herstellung und ihre verwendung.