NO844359L - Fremgangsmaate ved fremstilling av nye alkoxyiminoderivater av 5-acyl-2(1h)-pyridinoner - Google Patents

Fremgangsmaate ved fremstilling av nye alkoxyiminoderivater av 5-acyl-2(1h)-pyridinoner

Info

Publication number: NO844359L
Authority: NO; Norway
Prior art keywords: alcoxyimino; pyridinones; acyl; derivatives; procedure
Prior art date: 1983-11-03

Application number

NO844359A

Other languages

English (en)

Other versions

NO164538B (no

NO164538C (no

Inventor

Wintor D Jones Jr

Richard A Schnettler

Richard C Dage

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-11-03

Filing date

1984-11-02

Publication date

1985-05-06

1984-11-02 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1985-05-06 Publication of NO844359L publication Critical patent/NO844359L/no

1990-07-09 Publication of NO164538B publication Critical patent/NO164538B/no

1990-10-17 Publication of NO164538C publication Critical patent/NO164538C/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

NO844359A 1983-11-03 1984-11-02 Analogifremgangsmaate ved fremstilling av terapeutisk aktive alkoxyminoderivater av 5-acyl-2(1h)-pyridinoner. NO164538C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US54839883A	1983-11-03	1983-11-03

Publications (3)

Publication Number	Publication Date
NO844359L true NO844359L (no)	1985-05-06
NO164538B NO164538B (no)	1990-07-09
NO164538C NO164538C (no)	1990-10-17

Family

ID=24188699

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO844359A NO164538C (no)	1983-11-03	1984-11-02	Analogifremgangsmaate ved fremstilling av terapeutisk aktive alkoxyminoderivater av 5-acyl-2(1h)-pyridinoner.

Country Status (18)

Country	Link
EP (1)	EP0140375B1 (no)
JP (1)	JPS60120862A (no)
KR (1)	KR900005012B1 (no)
AR (1)	AR240556A1 (no)
AT (1)	ATE80874T1 (no)
AU (1)	AU572214B2 (no)
CA (1)	CA1291138C (no)
DE (1)	DE3485933T2 (no)
DK (1)	DK524384A (no)
ES (1)	ES537295A0 (no)
GR (1)	GR80819B (no)
HU (1)	HU193464B (no)
IL (1)	IL73362A (no)
NO (1)	NO164538C (no)
NZ (1)	NZ210036A (no)
PH (2)	PH22188A (no)
PT (1)	PT79444B (no)
ZA (1)	ZA848428B (no)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3190800A (en) *	1961-09-29	1965-06-22	Atlas Chem Ind	Method of producing depressant effect
FR5428M (no) *	1966-03-28	1967-10-02
HU177578B (en) *	1976-08-27	1981-11-28	Chinoin Gyogyszer Es Vegyeszet	Process for preparing new 0-/3-amino-2-hydroxy-propyl/-amidoxime derivatives
US4220648A (en) *	1979-01-22	1980-09-02	The Upjohn Company	Antidiabetic 1,2-dihydro-2-oxo-6-neopentyl-nicotinic acids
US4313951A (en) *	1979-11-26	1982-02-02	Sterling Drug Inc.	3-Substituted-6-(lower-alkyl)-5-(pyridinyl)-2(1H)-pyridinones, their cardiotonic use and intermediates therefor
DE3005069A1 (de) *	1980-02-11	1981-08-20	Cassella Ag, 6000 Frankfurt	Pyridonderivate, ihre herstellung und ihre verwendung
US4305948A (en) *	1980-12-22	1981-12-15	Sterling Drug Inc.	N-Hydroxy-1,2-dihydro-2-oxo-5-(pyridinyl)-nicotinimidamide and their cardiotonic use
US4524149A (en) *	1982-03-15	1985-06-18	Sterling Drug Inc.	5-Alkanoyl-6-alkyl-2(1H)-pyridinones, their preparation and their cardiotonic use

1984
- 1984-10-29 ZA ZA848428A patent/ZA848428B/xx unknown
- 1984-10-30 DE DE8484113085T patent/DE3485933T2/de not_active Expired - Fee Related
- 1984-10-30 AT AT84113085T patent/ATE80874T1/de not_active IP Right Cessation
- 1984-10-30 EP EP84113085A patent/EP0140375B1/en not_active Expired - Lifetime
- 1984-10-30 IL IL73362A patent/IL73362A/xx unknown
- 1984-10-30 NZ NZ210036A patent/NZ210036A/en unknown
- 1984-10-30 AU AU34831/84A patent/AU572214B2/en not_active Ceased
- 1984-10-31 AR AR29844884A patent/AR240556A1/es active
- 1984-10-31 ES ES537295A patent/ES537295A0/es active Granted
- 1984-11-01 CA CA000466802A patent/CA1291138C/en not_active Expired - Lifetime
- 1984-11-01 GR GR80819A patent/GR80819B/el unknown
- 1984-11-01 JP JP59229066A patent/JPS60120862A/ja active Granted
- 1984-11-02 PH PH31401A patent/PH22188A/en unknown
- 1984-11-02 KR KR1019840006867A patent/KR900005012B1/ko not_active Expired
- 1984-11-02 DK DK524384A patent/DK524384A/da not_active Application Discontinuation
- 1984-11-02 NO NO844359A patent/NO164538C/no unknown
- 1984-11-02 PT PT79444A patent/PT79444B/pt not_active IP Right Cessation
- 1984-11-02 PH PH31400A patent/PH21171A/en unknown
- 1984-11-02 HU HU844080A patent/HU193464B/hu not_active IP Right Cessation

Also Published As

Publication number	Publication date
EP0140375A3 (en)	1988-06-22
EP0140375B1 (en)	1992-09-23
PH22188A (en)	1988-06-28
KR850003715A (ko)	1985-06-26
DK524384D0 (da)	1984-11-02
DK524384A (da)	1985-05-04
GR80819B (en)	1985-03-04
JPH0477745B2 (no)	1992-12-09
HUT35646A (en)	1985-07-29
KR900005012B1 (ko)	1990-07-16
ES8507116A1 (es)	1985-08-16
ZA848428B (en)	1985-06-26
NO164538B (no)	1990-07-09
CA1291138C (en)	1991-10-22
PH21171A (en)	1987-08-07
IL73362A (en)	1989-03-31
AU3483184A (en)	1985-05-09
NO164538C (no)	1990-10-17
IL73362A0 (en)	1985-01-31
PT79444B (en)	1986-09-15
JPS60120862A (ja)	1985-06-28
ATE80874T1 (de)	1992-10-15
ES537295A0 (es)	1985-08-16
EP0140375A2 (en)	1985-05-08
DE3485933T2 (de)	1993-02-11
PT79444A (en)	1984-12-01
DE3485933D1 (de)	1992-10-29
AU572214B2 (en)	1988-05-05
AR240556A1 (es)	1990-05-31
HU193464B (en)	1987-10-28
NZ210036A (en)	1987-08-31

Publication	Publication Date	Title
NO803868L (no)	1981-06-22	Fremgangsmaate ved fremstilling av nye kinazolinderivater
NO860425L (no)	1986-08-08	Fremgangsmaate ved fremstilling av nye 11-beta-fenylgonaner
NO811731L (no)	1981-11-23	Fremgangsmaate for fremstilling av imidazo-rifamycin-derivater
NO813678L (no)	1982-05-03	Fremgangsmaate for fremstilling av karbostyrilderivater
NO792760L (no)	1980-02-26	Fremgangsmaate ved fremstilling av nye nafthydrinderivater
NO800650L (no)	1980-09-08	Fremgangsmaate ved fremstilling av nye indolderivater
NO792823L (no)	1980-03-03	Fremgangsmaate ved fremstilling av nye arginiamidderivater
NO841002L (no)	1984-09-17	Fremgangsmaate ved fremstilling av nye thiazolinderivater
NO831792L (no)	1983-11-25	Fremgangsmaate til fremstilling av nye imidazo-pyrazolopyrimidiner
NO844978L (no)	1985-06-13	Fremgangsmaate ved fremstilling av nye aminoguanidinderivater
NO843055L (no)	1985-01-30	Fremgangsmaate ved fremstilling av cephalosporinderivater
NO823637L (no)	1983-05-04	Fremgangsmaate for fremstilling av eburnamoninderivater
NO841691L (no)	1984-10-30	Fremgangsmaate ved fremstilling av nye 5-acyl-2-(1h)-pyridinoner
NO820281L (no)	1982-08-03	Fremgangsmaate ved fremstilling av n-(halogenmethyl)-acylamider
NO803247L (no)	1981-05-04	R fremgangsmaate ved fremstilling av nye pyridothienotriazine
NO851758L (no)	1985-11-04	Fremgangsmaate ved fremstilling av isokinolinderivater
NO813477L (no)	1981-10-15	Fremgangsmaate for fremstilling av karbostyrilderivater
NO802402L (no)	1981-02-16	R fremgangsmaate ved fremstilling av nye halovincamonderivate
NO833521L (no)	1984-04-02	Fremgangsmaate ved fremstilling av nye, terapeutisk virksomme vinylthioacetamido-oxacefalosporinderivater
NO851638L (no)	1985-10-28	Fremgangsmaate ved fremstilling av iminothiazolidin-derivater
NO801982L (no)	1981-01-05	Fremgangsmaate ved fremstilling av svovelholdige isokinolinderivater
NO812467L (no)	1982-01-19	Fremgangsmaate ved fremstilling av as-triazinderivater
NO844072L (no)	1985-04-15	Fremgangsmaate for fremstilling av nye aminopropanonforbindelser
NO812842L (no)	1982-02-24	Fremgangsmaate for fremstilling av aminoacetonitil-derivater
NO831874L (no)	1983-11-28	Fremgangsmaate for fremstilling av trifenylbuten-derivater