NO850771L - Bionedbrytbart polypeptid og dets anvendelse for gradvis frigjoering av legemidler - Google Patents

Bionedbrytbart polypeptid og dets anvendelse for gradvis frigjoering av legemidler

Info

Publication number
NO850771L
NO850771L NO850771A NO850771A NO850771L NO 850771 L NO850771 L NO 850771L NO 850771 A NO850771 A NO 850771A NO 850771 A NO850771 A NO 850771A NO 850771 L NO850771 L NO 850771L
Authority
NO
Norway
Prior art keywords
polymer
copolymer
acid
polypeptide
drug
Prior art date
Application number
NO850771A
Other languages
English (en)
Norwegian (no)
Inventor
Daniel Bichon
Original Assignee
Battelle Memorial Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Battelle Memorial Institute filed Critical Battelle Memorial Institute
Publication of NO850771L publication Critical patent/NO850771L/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227—Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G73/00—Macromolecular compounds obtained by reactions forming a linkage containing nitrogen with or without oxygen or carbon in the main chain of the macromolecule, not provided for in groups C08G12/00 - C08G71/00
    • C08G73/06—Polycondensates having nitrogen-containing heterocyclic rings in the main chain of the macromolecule
    • C08G73/10—Polyimides; Polyester-imides; Polyamide-imides; Polyamide acids or similar polyimide precursors
    • C08G73/1092—Polysuccinimides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A61L2300/604—Biodegradation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/29—Polyamino acid or polypeptide with an uninterrupted series of peptide repeating units

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Polyamides (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
NO850771A 1983-07-01 1985-02-26 Bionedbrytbart polypeptid og dets anvendelse for gradvis frigjoering av legemidler NO850771L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH361983 1983-07-01

Publications (1)

Publication Number Publication Date
NO850771L true NO850771L (no) 1985-02-26

Family

ID=4259870

Family Applications (1)

Application Number Title Priority Date Filing Date
NO850771A NO850771L (no) 1983-07-01 1985-02-26 Bionedbrytbart polypeptid og dets anvendelse for gradvis frigjoering av legemidler

Country Status (11)

Country Link
US (1) US4675381A (da)
EP (2) EP0130935B1 (da)
JP (1) JPS60501759A (da)
AT (1) ATE26584T1 (da)
AU (1) AU2698684A (da)
CA (1) CA1241322A (da)
DE (1) DE3463211D1 (da)
DK (1) DK88385D0 (da)
FI (1) FI73448C (da)
NO (1) NO850771L (da)
WO (1) WO1985000372A1 (da)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288498A (en) * 1985-05-01 1994-02-22 University Of Utah Research Foundation Compositions of oral nondissolvable matrixes for transmucosal administration of medicaments
JPS60237015A (ja) * 1984-05-11 1985-11-25 Koken:Kk 医薬徐放剤
US4880635B1 (en) * 1984-08-08 1996-07-02 Liposome Company Dehydrated liposomes
DE3581471D1 (de) * 1984-10-19 1991-02-28 Battelle Memorial Institute Durch mikroorganismen abbaubares polypeptid und seine verwendung fuer die fortschreitende abgabe von medikamenten.
US4863735A (en) * 1985-02-19 1989-09-05 Massachusetts Institute Of Technology Biodegradable polymeric drug delivery system with adjuvant activity
CS252559B1 (en) * 1985-03-22 1987-09-17 Frantisek Rypacek Polymer stabilizer of emulsion type water in oil
US4895724A (en) * 1985-06-07 1990-01-23 Pfizer Inc. Chitosan compositions for controlled and prolonged release of macromolecules
CH667874A5 (fr) * 1985-12-19 1988-11-15 Battelle Memorial Institute Polypeptide synthetique biodegradable et son utilisation pour la preparation de medicaments.
IL78826A (en) * 1986-05-19 1991-05-12 Yissum Res Dev Co Precursor composition for the preparation of a biodegradable implant for the sustained release of an active material and such implants prepared therefrom
CA1257199A (en) * 1986-05-20 1989-07-11 Paul Y. Wang Preparation containing bioactive macromolecular substance for multi-months release in vivo
DE3700128A1 (de) * 1987-01-03 1988-07-14 Hoechst Ag Biologisch abbaubare poly- (hydroxyalkyl)- aminodicarbonsaeure-derivate, verfahren zu ihrer herstellung und verwendung derselben fuer depotzubereitungen mit kontrollierter wirkstoffabgabe
US4916204A (en) * 1987-07-31 1990-04-10 Massachusetts Institute Of Technology Pure polyanhydride from dicarboxylic acid and coupling agent
US5681543A (en) * 1988-02-29 1997-10-28 Shering Aktiengesellschaft Polymer-bonded complexing agents and pharmaceutical agents containing them for MRI
GB8805286D0 (en) * 1988-03-05 1988-04-07 Schering Agrochemicals Ltd Trypanocides
US5023080A (en) * 1988-06-17 1991-06-11 Basic Bio Systems, Inc. Time release protein
US5700479A (en) * 1988-12-23 1997-12-23 Guidor Ab Surgical element and method for selective tissue regeneration
US4990336A (en) * 1989-02-08 1991-02-05 Biosearch, Inc. Sustained release dosage form
US5126147A (en) * 1990-02-08 1992-06-30 Biosearch, Inc. Sustained release dosage form
GB9107628D0 (en) 1991-04-10 1991-05-29 Moonbrook Limited Preparation of diagnostic agents
US5993805A (en) 1991-04-10 1999-11-30 Quadrant Healthcare (Uk) Limited Spray-dried microparticles and their use as therapeutic vehicles
GB9204918D0 (en) 1992-03-06 1992-04-22 Nycomed As Chemical compounds
DE69427895T2 (de) * 1993-11-24 2002-04-11 Rhodia Chimie, Courbevoie Verfahren zur Herstellung von Polyimiden oder ihren biologisch abbaubauren polypeptidischen Hydrolysaten
FR2712892B1 (fr) * 1993-11-24 1995-12-22 Rhone Poulenc Chimie Procédé de préparation de polyimides ou de leurs hydrolysats biodégradables.
US5904935A (en) * 1995-06-07 1999-05-18 Alza Corporation Peptide/protein suspending formulations
DE19545678A1 (de) * 1995-12-07 1997-06-12 Goldschmidt Ag Th Copolymere Polyaminosäureester
US6231888B1 (en) 1996-01-18 2001-05-15 Perio Products Ltd. Local delivery of non steroidal anti inflammatory drugs (NSAIDS) to the colon as a treatment for colonic polyps
US6441025B2 (en) * 1996-03-12 2002-08-27 Pg-Txl Company, L.P. Water soluble paclitaxel derivatives
CA2277011A1 (en) * 1997-01-13 1998-07-16 Universite Laval Membrane-permeable derivatives converted intracellularly into active peptides
US6517869B1 (en) 1997-12-12 2003-02-11 Expression Genetics, Inc. Positively charged poly(alpha-(omega-aminoalkyl)lycolic acid) for the delivery of a bioactive agent via tissue and cellular uptake
DE19822599C2 (de) * 1998-05-20 2003-02-06 Goldschmidt Ag Th Copolymere hydrophob modifizierte Polyasparaginsäureesteramide und ihre Verwendung
DE19822600C2 (de) * 1998-05-20 2003-08-21 Goldschmidt Ag Th Copolymere, hydrophob modifizierte Polyasparaginsäureester mit erhöhter Molekularmasse
US6531152B1 (en) 1998-09-30 2003-03-11 Dexcel Pharma Technologies Ltd. Immediate release gastrointestinal drug delivery system
US6632451B2 (en) 1999-06-04 2003-10-14 Dexcel Pharma Technologies Ltd. Delayed total release two pulse gastrointestinal drug delivery system
CA2401327C (en) * 2000-03-03 2014-05-06 Valentis, Inc. Nucleic acid formulations comprising poly-amino acids for gene delivery and methods of use
EP2279757A3 (en) 2000-06-02 2011-08-03 Bracco Suisse SA Compounds for targeting endothelial cells
JP3819845B2 (ja) * 2001-04-06 2006-09-13 ブラッコ・リサーチ・ソシエテ・アノニム 流体で充填された空洞内の局所物理パラメータの改善された測定方法
AUPR610501A0 (en) * 2001-07-04 2001-07-26 Smart Drug Systems Inc Treatment of parasitic disease
US20030109432A1 (en) * 2001-12-10 2003-06-12 Zuo William W. Anticancer polypeptide-metal complexes and compositions, methods of making, and methods of using same
KR101476067B1 (ko) 2002-09-06 2014-12-23 인설트 테라페틱스, 인코퍼레이티드 공유결합된 치료제 전달을 위한 사이클로덱스트린-기초 중합체
US20070128117A1 (en) * 2003-02-04 2007-06-07 Bracco International B.V. Ultrasound contrast agents and process for the preparation thereof
DK1590006T3 (da) * 2003-02-04 2010-12-20 Bracco Suisse Sa Ultralydskontrastmidler og fremgangsmåde til frembringelse deraf
WO2005063305A1 (en) * 2003-12-22 2005-07-14 Bracco Research Sa Gas-filled microvesicle assembly for contrast imaging
US20060067972A1 (en) * 2004-06-23 2006-03-30 Flowmedica, Inc. Devices for renal-based heart failure treatment
US9248204B2 (en) 2004-08-18 2016-02-02 Bracco Suisse S.A. Gas-filled microvesicles composition for contrast imaging
EP1714642A1 (en) 2005-04-18 2006-10-25 Bracco Research S.A. Pharmaceutical composition comprising gas-filled microcapsules for ultrasound mediated delivery
JPWO2007049770A1 (ja) 2005-10-28 2009-04-30 明治製菓株式会社 緑膿菌の外膜タンパク質ｐａ５１５８
DE602006007177D1 (de) 2005-12-05 2009-07-16 Nitto Denko Corp Polyglutamat-aminosäure-konjugate und verfahren
JPWO2007114340A1 (ja) 2006-03-30 2009-08-20 明治製菓株式会社 緑膿菌の外膜タンパク質ｐａ０４２７
US20080176958A1 (en) 2007-01-24 2008-07-24 Insert Therapeutics, Inc. Cyclodextrin-based polymers for therapeutics delivery
US20080181852A1 (en) * 2007-01-29 2008-07-31 Nitto Denko Corporation Multi-functional Drug Carriers
CN101674852A (zh) * 2007-04-10 2010-03-17 日东电工株式会社 多功能聚谷氨酸盐药物载体
CN101707869A (zh) * 2007-05-09 2010-05-12 日东电工株式会社 具有多种药物的聚谷氨酸盐结合物和聚谷氨酸盐-氨基酸结合物
EP2155255B1 (en) 2007-05-09 2013-08-14 Nitto Denko Corporation Compositions that include a hydrophobic compound and a polyamino acid conjugate
DK2155254T3 (da) * 2007-05-09 2013-03-04 Nitto Denko Corp Med platinlægemidler konjugerede polymere
SG182975A1 (en) * 2007-06-29 2012-08-30 Meiji Seika Kaisha Pseudomonas aeruginosa outer membrane protein pa4710
EP2236515A4 (en) 2007-12-25 2012-10-31 Meiji Seika Kaisha COMPONENT PROTEIN PA1698 FOR PSEUDOMONAS AERUGINOSA TYPE-III SECRETION SYSTEM
CN104096236A (zh) * 2008-03-06 2014-10-15 日东电工株式会社 用于治疗癌症的聚合物紫杉醇结合物和方法
CA2774350A1 (en) * 2009-09-15 2011-03-24 Alomone Preclinical Ltd. Novel peptides isolated from spider venom, and uses thereof
CN102781237A (zh) * 2009-11-23 2012-11-14 天蓝制药公司 用于传递治疗剂的基于环糊精的聚合物
WO2011119995A2 (en) 2010-03-26 2011-09-29 Cerulean Pharma Inc. Formulations and methods of use
CN103561762A (zh) 2011-03-16 2014-02-05 明尼苏达大学董事会 诱导针对葡萄球菌属中细菌的免疫应答的组合物和方法
KR20150024315A (ko) 2012-05-07 2015-03-06 재단법인 목암생명공학연구소 포도상구균 감염 예방용 백신 조성물
US20140094432A1 (en) 2012-10-02 2014-04-03 Cerulean Pharma Inc. Methods and systems for polymer precipitation and generation of particles
US11191802B2 (en) 2018-04-06 2021-12-07 AMMA Therapeutics, Inc. Composition for controlled release of therapeutic agents
WO2025132906A1 (en) 2023-12-22 2025-06-26 Bracco Suisse Sa Focused ultrasound thermal ablation with thermal enhancers

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3230274A (en) * 1960-12-30 1966-01-18 Merck & Co Inc Preparation of linear polypeptides
US3371069A (en) * 1963-03-20 1968-02-27 Ajinomoto Kk Filaments and surgical sutures of polyl-glutamic acid partly esterified with lower alkanols and process therefor
JPS5031905B1 (da) * 1971-07-05 1975-10-16
CA1045977A (en) * 1973-05-17 1979-01-09 Arthur D. Little Biodegradable, implantable drug delivery device, and process for preparing and using the same
US4351337A (en) * 1973-05-17 1982-09-28 Arthur D. Little, Inc. Biodegradable, implantable drug delivery device, and process for preparing and using the same
US4356166A (en) * 1978-12-08 1982-10-26 University Of Utah Time-release chemical delivery system

Also Published As

Publication number Publication date
FI73448C (fi) 1987-10-09
DE3463211D1 (en) 1987-05-21
FI850835L (fi) 1985-02-28
ATE26584T1 (de) 1987-05-15
EP0150184A1 (fr) 1985-08-07
EP0130935A1 (fr) 1985-01-09
DK88385A (da) 1985-02-27
JPS60501759A (ja) 1985-10-17
US4675381A (en) 1987-06-23
AU2698684A (en) 1985-02-07
WO1985000372A1 (fr) 1985-01-31
DK88385D0 (da) 1985-02-27
FI850835A0 (fi) 1985-02-28
FI73448B (fi) 1987-06-30
EP0130935B1 (fr) 1987-04-15
CA1241322A (fr) 1988-08-30

Similar Documents

Publication Publication Date Title
NO850771L (no) Bionedbrytbart polypeptid og dets anvendelse for gradvis frigjoering av legemidler
US4976962A (en) Biodegradable polypeptide and the use thereof for the gradual release of drugs
US4892733A (en) Biodegradable synthesis polypeptide and its therapeutic use
US5654381A (en) Functionalized polyester graft copolymers
US5665831A (en) Biocompatible block copolymer
US4906473A (en) Biodegradable poly(hydroxyalkyl)amino dicarboxylic acid) derivatives, a process for their preparation, and the use thereof for depot formulations with controlled delivery of active ingredient
JP4680900B2 (ja) 分解可能で生体適合性があるブロックコポリマー
ES2628931T3 (es) Copolímeros multibloque segmentados de fases separadas biodegradables y liberación de polipétidos biológicamente activos
JPH08500387A (ja) 天然アミノ酸ｌ−チロシンの誘導体を含むポリアリーレート
US5026821A (en) Polymers of citric acid and diamines, a process for their preparation and their uses, in particular as carriers of drugs
CN104672199B (zh) 一种含双碘环碳酸酯化合物及其制备方法
NO302372B1 (no) Polykondensater som inneholder vinsyrederivater og anvendelse av disse, til fremstilling av ultralydkontrastmidler og depot-tilberedninger av virksomt stoff samt terapeutika og diagnostika inneholdende ultralydkontrastmiddelet
WO2003062298A1 (en) Co-poly(ester amide) and co-poly(ester urethane) compositions which exhibit biodegradability, methods for making same and uses for same
CN108517003B (zh) 成胶因子、水凝胶以及药物组合物
CN106749159B (zh) 5-炔丙氧基-三亚甲基碳酸酯及其制备方法和应用
JP2665522B2 (ja) 新規アルファーオキシ酸ポリマー
JPS60226530A (ja) フイルム形成重合材
JP5158716B2 (ja) 乳酸残基を含有するデプシペプチド
Ogueri et al. Polyphosphazene-based biomaterials for regenerative engineering
EP1806377B1 (en) Temperature-responsive depsipeptide polymer
JPH0667886B2 (ja) 高分子化合物
Kuroyanagi et al. Preparation of graft polypeptide binding bleomycin derivative
Jin Synthetic functionalized biodegradable polymers and their composites with inorganics
JPH0691899B2 (ja) 抗血液凝固性高分子材料