NO854167L - Antigene peptidforbindelser. - Google Patents

Antigene peptidforbindelser.

Info

Publication number: NO854167L
Authority: NO; Norway
Prior art keywords: peptide; peptide compound; ldh; antigenic; amino acid
Prior art date: 1984-10-19

Application number

NO854167A

Other languages

English (en)

Norwegian (no)

Inventor

Erwin Goldberg

Thomas E Wheat

Original Assignee

Univ Northwestern

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-10-19

Filing date

1985-10-18

Publication date

1986-04-21

1985-10-18 Application filed by Univ Northwestern filed Critical Univ Northwestern

1986-04-21 Publication of NO854167L publication Critical patent/NO854167L/no

Links

108090000765 processed proteins & peptides Proteins 0.000 claims description 51
150000001875 compounds Chemical class 0.000 claims description 25
230000000890 antigenic effect Effects 0.000 claims description 19
108010028554 LDL Cholesterol Proteins 0.000 claims description 11
125000001433 C-terminal amino-acid group Chemical group 0.000 claims description 4
DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 4
150000008575 L-amino acids Chemical group 0.000 claims description 3
FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims description 3
KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 claims description 3
239000004472 Lysine Substances 0.000 claims description 3
229930182817 methionine Natural products 0.000 claims description 3
239000004471 Glycine Substances 0.000 claims description 2
WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims 1
CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 claims 1
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 1
ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims 1
ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 1
KDXKERNSBIXSRK-YFKPBYRVSA-N L-lysine Chemical compound NCCCC[C@H](N)C(O)=O KDXKERNSBIXSRK-YFKPBYRVSA-N 0.000 claims 1
OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims 1
KZSNJWFQEVHDMF-BYPYZUCNSA-N L-valine Chemical compound CC(C)[C@H](N)C(O)=O KZSNJWFQEVHDMF-BYPYZUCNSA-N 0.000 claims 1
ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 1
KZSNJWFQEVHDMF-UHFFFAOYSA-N Valine Natural products CC(C)C(N)C(O)=O KZSNJWFQEVHDMF-UHFFFAOYSA-N 0.000 claims 1
235000003704 aspartic acid Nutrition 0.000 claims 1
OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 claims 1
235000013922 glutamic acid Nutrition 0.000 claims 1
239000004220 glutamic acid Substances 0.000 claims 1
235000004554 glutamine Nutrition 0.000 claims 1
ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims 1
235000005772 leucine Nutrition 0.000 claims 1
235000018977 lysine Nutrition 0.000 claims 1
235000006109 methionine Nutrition 0.000 claims 1
235000002374 tyrosine Nutrition 0.000 claims 1
OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims 1
235000014393 valine Nutrition 0.000 claims 1
239000004474 valine Substances 0.000 claims 1
150000001413 amino acids Chemical group 0.000 description 17
102000004196 processed proteins & peptides Human genes 0.000 description 15
DTQVDTLACAAQTR-UHFFFAOYSA-N Trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 description 6
230000035558 fertility Effects 0.000 description 6
238000000034 method Methods 0.000 description 6
125000006239 protecting group Chemical group 0.000 description 6
229960005486 vaccine Drugs 0.000 description 6
230000027455 binding Effects 0.000 description 5
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
230000015572 biosynthetic process Effects 0.000 description 4
238000011160 research Methods 0.000 description 4
229920005989 resin Polymers 0.000 description 4
239000011347 resin Substances 0.000 description 4
238000003786 synthesis reaction Methods 0.000 description 4
WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
YMWUJEATGCHHMB-UHFFFAOYSA-N Dichloromethane Chemical compound ClCCl YMWUJEATGCHHMB-UHFFFAOYSA-N 0.000 description 3
108010044467 Isoenzymes Proteins 0.000 description 3
241000124008 Mammalia Species 0.000 description 3
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 3
125000003277 amino group Chemical group 0.000 description 3
239000003153 chemical reaction reagent Substances 0.000 description 3
230000008878 coupling Effects 0.000 description 3
238000010168 coupling process Methods 0.000 description 3
238000005859 coupling reaction Methods 0.000 description 3
238000010511 deprotection reaction Methods 0.000 description 3
239000012530 fluid Substances 0.000 description 3
230000003053 immunization Effects 0.000 description 3
238000002649 immunization Methods 0.000 description 3
210000005000 reproductive tract Anatomy 0.000 description 3
210000002966 serum Anatomy 0.000 description 3
239000007790 solid phase Substances 0.000 description 3
238000010532 solid phase synthesis reaction Methods 0.000 description 3
239000000243 solution Substances 0.000 description 3
229960000814 tetanus toxoid Drugs 0.000 description 3
MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 description 2
QOSSAOTZNIDXMA-UHFFFAOYSA-N Dicylcohexylcarbodiimide Chemical compound C1CCCCC1N=C=NC1CCCCC1 QOSSAOTZNIDXMA-UHFFFAOYSA-N 0.000 description 2
108090000790 Enzymes Proteins 0.000 description 2
102000004190 Enzymes Human genes 0.000 description 2
CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 description 2
125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 description 2
-1 amino-protected lysine Chemical class 0.000 description 2
238000013459 approach Methods 0.000 description 2
230000000903 blocking effect Effects 0.000 description 2
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
229940124566 female contraceptive agent Drugs 0.000 description 2
108010074605 gamma-Globulins Proteins 0.000 description 2
230000001900 immune effect Effects 0.000 description 2
238000011534 incubation Methods 0.000 description 2
238000010255 intramuscular injection Methods 0.000 description 2
239000007927 intramuscular injection Substances 0.000 description 2
238000011835 investigation Methods 0.000 description 2
239000000203 mixture Substances 0.000 description 2
229910052757 nitrogen Inorganic materials 0.000 description 2
238000005406 washing Methods 0.000 description 2
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
IMUSLIHRIYOHEV-ZETCQYMHSA-N (2s)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-4-methylsulfanylbutanoic acid Chemical compound CSCC[C@@H](C(O)=O)NC(=O)OC(C)(C)C IMUSLIHRIYOHEV-ZETCQYMHSA-N 0.000 description 1
CKGCFBNYQJDIGS-LBPRGKRZSA-N (2s)-2-azaniumyl-6-(phenylmethoxycarbonylamino)hexanoate Chemical compound [O-]C(=O)[C@@H]([NH3+])CCCCNC(=O)OCC1=CC=CC=C1 CKGCFBNYQJDIGS-LBPRGKRZSA-N 0.000 description 1
CHRJZRDFSQHIFI-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;styrene Chemical compound C=CC1=CC=CC=C1.C=CC1=CC=CC=C1C=C CHRJZRDFSQHIFI-UHFFFAOYSA-N 0.000 description 1
FPQQSJJWHUJYPU-UHFFFAOYSA-N 3-(dimethylamino)propyliminomethylidene-ethylazanium;chloride Chemical compound Cl.CCN=C=NCCCN(C)C FPQQSJJWHUJYPU-UHFFFAOYSA-N 0.000 description 1
HJBUBXIDMQBSQW-UHFFFAOYSA-N 4-(4-diazoniophenyl)benzenediazonium Chemical compound C1=CC([N+]#N)=CC=C1C1=CC=C([N+]#N)C=C1 HJBUBXIDMQBSQW-UHFFFAOYSA-N 0.000 description 1
241000283707 Capra Species 0.000 description 1
KRHYYFGTRYWZRS-UHFFFAOYSA-N Fluorane Chemical compound F KRHYYFGTRYWZRS-UHFFFAOYSA-N 0.000 description 1
SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 1
101001130171 Homo sapiens L-lactate dehydrogenase C chain Proteins 0.000 description 1
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 1
VGALFAWDSNRXJK-VIFPVBQESA-N L-aspartic acid beta-benzyl ester Chemical compound OC(=O)[C@@H](N)CC(=O)OCC1=CC=CC=C1 VGALFAWDSNRXJK-VIFPVBQESA-N 0.000 description 1
102000003855 L-lactate dehydrogenase Human genes 0.000 description 1
102100031357 L-lactate dehydrogenase C chain Human genes 0.000 description 1
108700023483 L-lactate dehydrogenases Proteins 0.000 description 1
IMTUWVJPCQPJEE-IUCAKERBSA-N Met-Lys Chemical compound CSCC[C@H](N)C(=O)N[C@H](C(O)=O)CCCCN IMTUWVJPCQPJEE-IUCAKERBSA-N 0.000 description 1
101001130170 Mus musculus L-lactate dehydrogenase C chain Proteins 0.000 description 1
241001460678 Napo <wasp> Species 0.000 description 1
KAFHLONDOVSENM-HNNXBMFYSA-N O-Benzyl-L-tyrosine Chemical compound C1=CC(C[C@H](N)C(O)=O)=CC=C1OCC1=CC=CC=C1 KAFHLONDOVSENM-HNNXBMFYSA-N 0.000 description 1
241000283973 Oryctolagus cuniculus Species 0.000 description 1
239000004793 Polystyrene Substances 0.000 description 1
229920005654 Sephadex Polymers 0.000 description 1
239000012507 Sephadex™ Substances 0.000 description 1
102000004142 Trypsin Human genes 0.000 description 1
108090000631 Trypsin Proteins 0.000 description 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
AGXGCFSECFQMKB-NHCYSSNCSA-N Val-Leu-Asp Chemical compound CC(C)C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)O)NC(=O)[C@H](C(C)C)N AGXGCFSECFQMKB-NHCYSSNCSA-N 0.000 description 1
NLNCNKIVJPEFBC-DLOVCJGASA-N Val-Val-Glu Chemical compound CC(C)[C@H](N)C(=O)N[C@@H](C(C)C)C(=O)N[C@H](C(O)=O)CCC(O)=O NLNCNKIVJPEFBC-DLOVCJGASA-N 0.000 description 1
238000002835 absorbance Methods 0.000 description 1
230000004520 agglutination Effects 0.000 description 1
150000003862 amino acid derivatives Chemical class 0.000 description 1
239000011324 bead Substances 0.000 description 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
125000001584 benzyloxycarbonyl group Chemical group C(=O)(OCC1=CC=CC=C1)* 0.000 description 1
239000004202 carbamide Substances 0.000 description 1
230000015556 catabolic process Effects 0.000 description 1
210000003756 cervix mucus Anatomy 0.000 description 1
125000004218 chloromethyl group Chemical group [H]C([H])(Cl)* 0.000 description 1
238000003776 cleavage reaction Methods 0.000 description 1
229920006026 co-polymeric resin Polymers 0.000 description 1
239000000470 constituent Substances 0.000 description 1
238000006731 degradation reaction Methods 0.000 description 1
238000011033 desalting Methods 0.000 description 1
238000011161 development Methods 0.000 description 1
238000000502 dialysis Methods 0.000 description 1
230000029087 digestion Effects 0.000 description 1
230000000694 effects Effects 0.000 description 1
210000000416 exudates and transudate Anatomy 0.000 description 1
238000002523 gelfiltration Methods 0.000 description 1
229910000042 hydrogen bromide Inorganic materials 0.000 description 1
229910000040 hydrogen fluoride Inorganic materials 0.000 description 1
230000007062 hydrolysis Effects 0.000 description 1
238000006460 hydrolysis reaction Methods 0.000 description 1
230000036512 infertility Effects 0.000 description 1
208000000509 infertility Diseases 0.000 description 1
231100000535 infertility Toxicity 0.000 description 1
230000002452 interceptive effect Effects 0.000 description 1
JDNTWHVOXJZDSN-UHFFFAOYSA-N iodoacetic acid Chemical compound OC(=O)CI JDNTWHVOXJZDSN-UHFFFAOYSA-N 0.000 description 1
239000007788 liquid Substances 0.000 description 1
125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 description 1
239000012836 macromolecular constituent Substances 0.000 description 1
210000003101 oviduct Anatomy 0.000 description 1
238000010647 peptide synthesis reaction Methods 0.000 description 1
239000000546 pharmaceutical excipient Substances 0.000 description 1
ZWLUXSQADUDCSB-UHFFFAOYSA-N phthalaldehyde Chemical class O=CC1=CC=CC=C1C=O ZWLUXSQADUDCSB-UHFFFAOYSA-N 0.000 description 1
229920002223 polystyrene Polymers 0.000 description 1
229920003053 polystyrene-divinylbenzene Polymers 0.000 description 1
229920000915 polyvinyl chloride Polymers 0.000 description 1
239000004800 polyvinyl chloride Substances 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
239000000047 product Substances 0.000 description 1
239000003223 protective agent Substances 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
238000000746 purification Methods 0.000 description 1
238000003127 radioimmunoassay Methods 0.000 description 1
230000001850 reproductive effect Effects 0.000 description 1
238000004366 reverse phase liquid chromatography Methods 0.000 description 1
238000004007 reversed phase HPLC Methods 0.000 description 1
230000007017 scission Effects 0.000 description 1
210000000582 semen Anatomy 0.000 description 1
239000011780 sodium chloride Substances 0.000 description 1
239000006228 supernatant Substances 0.000 description 1
230000002194 synthesizing effect Effects 0.000 description 1
229920003002 synthetic resin Polymers 0.000 description 1
239000000057 synthetic resin Substances 0.000 description 1
230000009885 systemic effect Effects 0.000 description 1
238000012360 testing method Methods 0.000 description 1
210000001550 testis Anatomy 0.000 description 1
239000012588 trypsin Substances 0.000 description 1
239000003643 water by type Substances 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO854167A 1984-10-19 1985-10-18 Antigene peptidforbindelser. NO854167L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/663,057 US4585587A (en)	1984-10-19	1984-10-19	Antigenic peptide compounds

Publications (1)

Publication Number	Publication Date
NO854167L true NO854167L (no)	1986-04-21

Family

ID=24660313

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO854167A NO854167L (no)	1984-10-19	1985-10-18	Antigene peptidforbindelser.

Country Status (7)

Country	Link
US (1)	US4585587A (da)
EP (1)	EP0179412A3 (da)
JP (1)	JPS61112098A (da)
AU (1)	AU4885885A (da)
DK (1)	DK480885A (da)
NO (1)	NO854167L (da)
ZA (1)	ZA858069B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU8192987A (en) *	1986-12-01	1988-06-16	Northwestern University	Human ldh-c4 cdna sequences encoding antigenic regions
US4782136A (en) *	1986-12-01	1988-11-01	Northwestern University	Synthetic peptide compounds producing anitbodies binding to human LDH-C.sub.
JPH0742313B2 (ja) *	1988-03-28	1995-05-10	日立化成工業株式会社	新規ペプチド、その塩及びペプチド性抗アレルギー剤
DE69131014T2 (de) *	1990-11-21	1999-10-07	Washington University, St. Louis	Rekombinante avirulente salmonella antifruchtbarkeitsimpfstoffe
DK31991D0 (da) *	1991-02-25	1991-02-25	Carlbiotech Ltd As	Peptid og farmaceutisk praeparat indeholdende et saadant peptid
DK53191D0 (da) *	1991-03-25	1991-03-25	Carlbiotech Ltd As	Organosvovlforbindelse og farmaceutisk praeparat indeholdende en saadan forbindelse
US5433219A (en) *	1992-09-23	1995-07-18	Spery; Nanette S.	Receptive condom assembly

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4290944A (en) *	1980-07-31	1981-09-22	Northwestern University	Antigenic peptide compound
CA1238312A (en) *	1981-05-26	1988-06-21	Erwin Goldberg	Antigenic linear peptide compound
US4353822A (en) *	1981-05-26	1982-10-12	Northwestern University	Antigenic linear peptide compounds
US4392997A (en) *	1981-07-06	1983-07-12	Northwestern University	Antigenic peptide compounds

1984
- 1984-10-19 US US06/663,057 patent/US4585587A/en not_active Expired - Fee Related
1985
- 1985-10-18 NO NO854167A patent/NO854167L/no unknown
- 1985-10-18 AU AU48858/85A patent/AU4885885A/en not_active Abandoned
- 1985-10-18 EP EP85113235A patent/EP0179412A3/en not_active Withdrawn
- 1985-10-18 DK DK480885A patent/DK480885A/da not_active Application Discontinuation
- 1985-10-19 JP JP60234385A patent/JPS61112098A/ja active Pending
- 1985-10-21 ZA ZA858069A patent/ZA858069B/xx unknown

Also Published As

Publication number	Publication date
US4585587A (en)	1986-04-29
EP0179412A3 (en)	1988-08-24
ZA858069B (en)	1986-06-25
EP0179412A2 (en)	1986-04-30
DK480885A (da)	1986-04-20
JPS61112098A (ja)	1986-05-30
AU4885885A (en)	1986-04-24
DK480885D0 (da)	1985-10-18

Publication	Publication Date	Title
AU684577B2 (en)	1997-12-18	Chaperonin 10
JPS63500659A (ja)	1988-03-10	合成ペプチドに基づく抗狂犬病組成物および方法
Elsayed et al.	1989	Synthetic allergenic epitopes from the amino-terminal regions of the major allergens of hazel and birch pollen
US4392997A (en)	1983-07-12	Antigenic peptide compounds
NO854167L (no)	1986-04-21	Antigene peptidforbindelser.
US4290944A (en)	1981-09-22	Antigenic peptide compound
Van Eldik et al.	1983	Engineering of site-directed antisera against vertebrate calmodulin by using synthetic peptide immunogens containing an immunoreactive site.
US4310456A (en)	1982-01-12	Antigenic linear peptide compound
CA1270099A (en)	1990-06-05	Immunogenic hav peptides
US4578219A (en)	1986-03-25	Antigenic peptide compound
US4782136A (en)	1988-11-01	Synthetic peptide compounds producing anitbodies binding to human LDH-C.sub.
JPH04505614A (ja)	1992-10-01	タンパク質複合体
AU652611B2 (en)	1994-09-01	Analogs of piscine LHRH
EP0079934B1 (en)	1987-04-29	Antigenic linear peptide compounds
US4353822A (en)	1982-10-12	Antigenic linear peptide compounds
CN101362795A (zh)	2009-02-11	附睾蛋白酶抑制蛋白b细胞表位及包含此表位的抗原肽
Lee et al.	1984	Monoclonal antibodies to rabbit sperm autoantigens
US4377516A (en)	1983-03-22	Antigenic linear peptide compounds
US4354967A (en)	1982-10-19	Antigenic linear peptide compound
EP0088752B1 (en)	1986-01-22	Antigenic peptide compound
CA1181742A (en)	1985-01-29	Antigenic linear peptide compound
Oda et al.	1990	Production of propeptide-directed antibody: its application to the purification of proalbumin and analysis of proalbumin processing
何畏 et al.	2001	A Novel Contraceptive Vaccine: Design and Synthesis of the Chimeric Peptide Containing Multivalent Sperm-Specific Epitopes
CN101397332B (zh)	2012-03-07	附睾蛋白酶抑制剂的功能肽段及利用该功能肽段构建的多重抗原肽
CN101362796A (zh)	2009-02-11	附睾蛋白酶抑制蛋白b细胞表位及包含此表位的多重抗原肽