NO862138L - Analogifremgangsmaate for fremstilling av terapeutisk aktive n-fenyl-4-fenyl-1-piperazincarboxamidiner og beslektede forbindelser. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive n-fenyl-4-fenyl-1-piperazincarboxamidiner og beslektede forbindelser.

Info

Publication number
NO862138L
NO862138L NO862138A NO862138A NO862138L NO 862138 L NO862138 L NO 862138L NO 862138 A NO862138 A NO 862138A NO 862138 A NO862138 A NO 862138A NO 862138 L NO862138 L NO 862138L
Authority
NO
Norway
Prior art keywords
hydrogen
alkyl
formula
compound according
piperazinecarboxamidine
Prior art date
Application number
NO862138A
Other languages
English (en)
Norwegian (no)
Inventor
Jean-Claude Pascal
Original Assignee
Syntex Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Lab filed Critical Syntex Lab
Publication of NO862138L publication Critical patent/NO862138L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO862138A 1985-05-30 1986-05-29 Analogifremgangsmaate for fremstilling av terapeutisk aktive n-fenyl-4-fenyl-1-piperazincarboxamidiner og beslektede forbindelser. NO862138L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/739,393 US4713382A (en) 1985-05-30 1985-05-30 N-phenyl-4-phenyl-1-piperazinecarboxamidines and related compounds as antiarrhythmic agents

Publications (1)

Publication Number Publication Date
NO862138L true NO862138L (no) 1986-12-01

Family

ID=24972082

Family Applications (1)

Application Number Title Priority Date Filing Date
NO862138A NO862138L (no) 1985-05-30 1986-05-29 Analogifremgangsmaate for fremstilling av terapeutisk aktive n-fenyl-4-fenyl-1-piperazincarboxamidiner og beslektede forbindelser.

Country Status (16)

Country Link
US (1) US4713382A (de)
EP (1) EP0204265A1 (de)
JP (1) JPS61280486A (de)
KR (1) KR860008999A (de)
CN (1) CN86103798A (de)
AU (1) AU5805086A (de)
DD (1) DD247452A5 (de)
DK (1) DK253586A (de)
ES (1) ES8708132A1 (de)
FI (1) FI862279A7 (de)
GR (1) GR861370B (de)
HU (1) HU195201B (de)
IL (1) IL78963A0 (de)
NO (1) NO862138L (de)
PT (1) PT82675B (de)
ZA (1) ZA864023B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2180537T3 (es) * 1991-08-14 2003-02-16 Procter & Gamble Pharma Nuevas ureas 4-oxociclicas, utilizables como agentes antiarritmicos o antifibrilantes.
US9388126B2 (en) 2012-07-19 2016-07-12 Drexel University Sigma receptor ligands and methods of modulating cellular protein homeostasis using same
WO2019089902A1 (en) 2017-11-01 2019-05-09 Drexel University Compounds, compositions, and methods for treating diseases

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA574981A (en) * 1959-04-28 Allis-Chalmers Manufacturing Company Fluid pressure bearing and seal for centrifugal pump
GB948766A (en) * 1959-10-20 1964-02-05 May & Baker Ltd Trifluoromethylphenylpiperazine derivatives
US3655667A (en) * 1968-04-04 1972-04-11 Smith Kline French Lab 1-(2-benzoylcyclopropylmethyl)-4-phenylpiperazines
PH12016A (en) * 1972-09-22 1978-10-06 Rorer Inc William H Amidinoureas
US3793322A (en) * 1972-12-15 1974-02-19 Usv Pharma Corp 1,4-disubstituted piperazines
US3976643A (en) * 1973-07-13 1976-08-24 William H. Rorer, Inc. Guanidines
US3961056A (en) * 1974-02-11 1976-06-01 The Upjohn Company Substituted morpholine guanidines for the treatment of arrhythmic conditions
GB1514907A (en) * 1975-05-30 1978-06-21 Rorer Inc William H Process for the preparation of substituted phenylguanidines and substituted phenylguanidines when thus prepared
US4211867A (en) * 1976-03-19 1980-07-08 Mcneil Laboratories, Incorporated Nitrogen heterocyclic carboximidamide compounds
US4138561A (en) * 1977-09-30 1979-02-06 Bristol-Myers Company Cyanocarboxamidines and quinazoline process
EP0005385B1 (de) * 1978-04-27 1982-09-01 LAROCHE NAVARRON S.A. Société dite: Piperazinmethanimin-Derivate, Verfahren zu ihrer Herstellung und ihre therapeutischen Verwendungen
CH643549A5 (de) * 1979-08-25 1984-06-15 Merz & Co N-(trimethoxybenzyl)-n'-phenylpiperazine.
US4374835A (en) * 1980-01-31 1983-02-22 Laroche-Navarron, S.A. Piperazine derivatives of theophylline

Also Published As

Publication number Publication date
KR860008999A (ko) 1986-12-19
DD247452A5 (de) 1987-07-08
FI862279L (fi) 1986-12-01
ES8708132A1 (es) 1987-10-16
FI862279A7 (fi) 1986-12-01
ZA864023B (en) 1988-01-27
PT82675B (en) 1987-09-29
DK253586D0 (da) 1986-05-29
JPS61280486A (ja) 1986-12-11
AU5805086A (en) 1986-12-04
HU195201B (en) 1988-04-28
IL78963A0 (en) 1986-09-30
EP0204265A1 (de) 1986-12-10
PT82675A (en) 1986-06-01
US4713382A (en) 1987-12-15
GR861370B (en) 1986-09-17
ES555440A0 (es) 1987-10-16
DK253586A (da) 1986-12-01
HUT41016A (en) 1987-03-30
FI862279A0 (fi) 1986-05-29
CN86103798A (zh) 1987-06-10

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