NO885821L - Visse 2-substituerte adenosinderivater. - Google Patents

Visse 2-substituerte adenosinderivater.

Info

Publication number: NO885821L
Authority: NO; Norway
Prior art keywords: substituted; certain; adenosin; derivatives; adenosin derivatives
Prior art date: 1988-01-07

Application number

NO88885821A

Other languages

English (en)

Other versions

NO169843C (no

NO169843B (no

NO885821D0 (no

Inventor

Alan J Hutchison

John E Francis

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-01-07

Filing date

1988-12-30

Publication date

1989-07-10

1988-12-30 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1988-12-30 Publication of NO885821D0 publication Critical patent/NO885821D0/no

1989-07-10 Publication of NO885821L publication Critical patent/NO885821L/no

1992-05-04 Publication of NO169843B publication Critical patent/NO169843B/no

1992-08-12 Publication of NO169843C publication Critical patent/NO169843C/no

Links

-1 2-SUBSTITUTED ADENOSIN Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/173—Purine radicals with 2-deoxyribosyl as the saccharide radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Molecular Biology (AREA)
Animal Behavior & Ethology (AREA)
Genetics & Genomics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Biochemistry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

NO885821A 1988-01-07 1988-12-30 Analogifremgangsmaate for fremstilling av visse 2-substituerte adenosinderivater NO169843C (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US14205588A	1988-01-07	1988-01-07
US07/193,968 US5034381A (en)	1988-01-07	1988-05-13	2-(substituted amino) adenosines as antihypertensives

Publications (4)

Publication Number	Publication Date
NO885821D0 NO885821D0 (no)	1988-12-30
NO885821L true NO885821L (no)	1989-07-10
NO169843B NO169843B (no)	1992-05-04
NO169843C NO169843C (no)	1992-08-12

Family

ID=26839719

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO885821A NO169843C (no)	1988-01-07	1988-12-30	Analogifremgangsmaate for fremstilling av visse 2-substituerte adenosinderivater

Country Status (17)

Country	Link
US (1)	US5034381A (no)
EP (1)	EP0323807A3 (no)
JP (1)	JPH01265100A (no)
KR (1)	KR890011903A (no)
AU (1)	AU618055B2 (no)
CA (1)	CA1325209C (no)
DD (1)	DD283402A5 (no)
DK (1)	DK5089A (no)
FI (1)	FI90430C (no)
HU (1)	HU202550B (no)
IL (1)	IL88877A0 (no)
MX (1)	MX14446A (no)
NO (1)	NO169843C (no)
NZ (1)	NZ227542A (no)
PH (1)	PH26672A (no)
PT (1)	PT89392B (no)
ZA (1)	ZA8984B (no)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4977144A (en) *	1988-08-02	1990-12-11	Ciba-Geigy Corporation	Imidazo[4,5-b]pyridine derivatives as cardiovascular agents
AU3820989A (en) *	1988-08-02	1990-02-08	Ciba-Geigy Ag	7-amino-3-beta-d-ribofuranosyl-3h-imidazo(4,5-b) pyridin-5-amine derivatives
US5189027A (en)	1990-11-30	1993-02-23	Yamasa Shoyu Kabushiki Kaisha	2-substituted adenosine derivatives and pharmaceutical compositions for circulatory diseases
US5206222A (en) *	1991-05-22	1993-04-27	Vanderbilt University	Methods for the reduction of myocardial reperfusion injury
IT1254915B (it) *	1992-04-24	1995-10-11	Gloria Cristalli	Derivati di adenosina ad attivita' a2 agonista
IL107101A0 (en) *	1992-09-30	1993-12-28	Merrell Dow Pharma	2-substituted adenosines with a-2 receptor affinity
US5426101A (en) *	1992-09-30	1995-06-20	Merrell Dow Pharmaceuticals Inc.	2-substituted adenosines with A-2 receptor affinity
AU6516494A (en) *	1993-04-15	1994-11-08	New York University	Adenosine receptor agonists for the promotion of wound healing
WO1996003134A1 (en) *	1994-07-21	1996-02-08	Thomas Jefferson University	Treatment of diarrhea with 2-substituted adenosine derivatives
AU740770B2 (en)	1997-06-18	2001-11-15	Aderis Pharmaceuticals, Inc.	Compositions and methods for preventing restenosis following revascularization procedures
EP1021195A1 (en)	1997-10-07	2000-07-26	The Regents Of The University Of California	Treating occlusive peripheral vascular disease and coronary disease with combinations of heparin and an adenoside a2 agonist, or with adenosine
US5972903A (en) *	1997-10-07	1999-10-26	Regents Of The University Of California Corporation	Method for promoting angiogenesis using heparin and adenosine
WO2000002892A1 (fr) *	1998-07-09	2000-01-20	Sankyo Company, Limited	Nouveaux composes antibacteriens
AR023463A1 (es)	1999-04-16	2002-09-04	Schering Corp	Uso de compuestos de azetidinona
TWI245047B (en) *	1999-08-20	2005-12-11	Sankyo Co	Novel A-500359 derivatives
US20050033044A1 (en)	2003-05-19	2005-02-10	Bristol-Myers Squibb Pharma Company	Methods for preparing 2-alkynyladenosine derivatives
CN101120002A (zh)	2005-02-17	2008-02-06	惠氏公司	环烷基稠合的吲哚、苯并噻吩、苯并呋喃和茚衍生物
US20090136460A1 (en) *	2007-07-10	2009-05-28	Vanderbilt University	Use of adenosine receptor ligands to promote cell adhesion in cell-based therapies
SG11201603063WA (en) *	2013-10-23	2016-05-30	Academia Sinica	Compounds for use in prevention and treatment of neurodegenerative diseases and pain

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1670265A1 (de) *	1967-08-25	1971-01-28	Boehringer Mannheim Gmbh	2-Amino-Adenosinderivate und Verfahren zu deren Herstellung
NL7203984A (no) *	1971-04-10	1972-10-12
US3917583A (en) *	1972-08-04	1975-11-04	Icn Pharmaceuticals	2-Substituted cyclic AMP derivatives
AR205247A1 (es) *	1973-02-07	1976-04-21	Icn Pharmaceuticals	Procedimiento para preparar derivados de amp 2-substituidos
JPS5630355B2 (no) *	1974-01-21	1981-07-14
AU5118979A (en) *	1978-10-16	1980-04-24	Takeda Chemical Industries Ltd.	2,6-diaminoebularines
JPS56152437U (no) *	1980-04-14	1981-11-14
US4501735A (en) *	1983-12-05	1985-02-26	Warner-Lambert Company	N6-(1- and 2-benzocycloalkyl) adenosines
DE3406533A1 (de) *	1984-02-23	1985-08-29	Boehringer Mannheim Gmbh, 6800 Mannheim	Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten
AU582359B2 (en) *	1984-04-18	1989-03-23	Nelson Research & Development Company	N-6 substituted adenosine derivatives as cardiac vasodilators
US4594350A (en) *	1984-07-30	1986-06-10	Reagents Of University Of Minnesota	(3-ethoxypropionate) esters of cyclaradine
US4683223A (en) *	1985-09-09	1987-07-28	Warner-Lambert Company	N6 -Benzopyrano-and benzothiopyrano adenosines and methods of use
US4593019A (en) *	1984-10-26	1986-06-03	Warner-Lambert Company	N6 -tricyclic adenosines
US4791103A (en) *	1985-02-08	1988-12-13	Warner-Lambert Company	2,N6 -disubstituted adenosines, derivatives and methods of use
US4600707A (en) *	1985-01-25	1986-07-15	Warner-Lambert Company	Benzothien-3-yl adenosine; benzothien-3-yl adenosine, S-oxide; and benzothien-3-yl, S,S-dioxide adenosine compounds
US4755594A (en) *	1986-01-31	1988-07-05	Warner-Lambert Company	N6 -substituted adenosines
JPH0723394B2 (ja) *	1986-11-27	1995-03-15	日本臓器製薬株式会社	新規アデノシン誘導体及び該化合物を有効成分として含有する医薬組成物
EP0277917A3 (en) *	1987-02-04	1990-03-28	Ciba-Geigy Ag	Certain adenosine 5'-carboxamide derivatives

1988
- 1988-05-13 US US07/193,968 patent/US5034381A/en not_active Expired - Fee Related
- 1988-12-29 EP EP88810900A patent/EP0323807A3/en not_active Withdrawn
- 1988-12-30 NO NO885821A patent/NO169843C/no unknown
1989
- 1989-01-03 IL IL88877A patent/IL88877A0/xx unknown
- 1989-01-04 FI FI890028A patent/FI90430C/fi not_active IP Right Cessation
- 1989-01-05 HU HU8933A patent/HU202550B/hu not_active IP Right Cessation
- 1989-01-05 PT PT89392A patent/PT89392B/pt not_active IP Right Cessation
- 1989-01-05 CA CA000587534A patent/CA1325209C/en not_active Expired - Fee Related
- 1989-01-05 MX MX1444689A patent/MX14446A/es unknown
- 1989-01-05 ZA ZA8984A patent/ZA8984B/xx unknown
- 1989-01-05 NZ NZ227542A patent/NZ227542A/en unknown
- 1989-01-05 DD DD89324859A patent/DD283402A5/de unknown
- 1989-01-06 AU AU27767/89A patent/AU618055B2/en not_active Ceased
- 1989-01-06 PH PH39015A patent/PH26672A/en unknown
- 1989-01-06 KR KR1019890000062A patent/KR890011903A/ko not_active Withdrawn
- 1989-01-06 JP JP64000590A patent/JPH01265100A/ja active Pending
- 1989-01-06 DK DK005089A patent/DK5089A/da not_active Application Discontinuation

Also Published As

Publication number	Publication date
HUT48904A (en)	1989-07-28
EP0323807A2 (en)	1989-07-12
NO169843C (no)	1992-08-12
CA1325209C (en)	1993-12-14
PH26672A (en)	1992-09-15
NO169843B (no)	1992-05-04
AU2776789A (en)	1989-07-13
HU202550B (en)	1991-03-28
DK5089D0 (da)	1989-01-06
MX14446A (es)	1994-01-31
FI890028A0 (fi)	1989-01-04
JPH01265100A (ja)	1989-10-23
US5034381A (en)	1991-07-23
DK5089A (da)	1989-07-08
EP0323807A3 (en)	1990-06-20
NO885821D0 (no)	1988-12-30
KR890011903A (ko)	1989-08-23
PT89392A (pt)	1990-02-08
ZA8984B (en)	1989-08-30
DD283402A5 (de)	1990-10-10
PT89392B (pt)	1993-09-30
FI890028A7 (fi)	1989-07-08
FI90430B (fi)	1993-10-29
FI90430C (fi)	1994-02-10
AU618055B2 (en)	1991-12-12
NZ227542A (en)	1992-03-26
IL88877A0 (en)	1989-08-15

Publication	Publication Date	Title
ATE101608T1 (de)	1994-03-15	Therapeutische chinuclidinderivate.
NL300161I2 (nl)	2005-02-01	Carbostyrilderivaten.
FI882505A7 (fi)	1988-11-30	Foerfarande foer framstaellning av terapeutiskt anvaendbara alkoxi-substituerade dihydrobensopyran-2-karboxylatderivat.
NO885821D0 (no)	1988-12-30	Visse 2-substituerte adenosinderivater.
FI884305A7 (fi)	1989-03-22	Uudet amidino-trisyklijohdokset.
DE3865544D1 (de)	1991-11-21	Vitamin d3-derivate.
FI880078A7 (fi)	1988-07-10	Foerfarande foer framstaellning av heteroaryl-3-oxo-propannitrilderivat.
DE58901056D1 (de)	1992-05-07	Dehydrocholecalciferolderivate.
DE3872153D1 (de)	1992-07-23	25-hydroxy-vitamin-d3-derivate.
ATE73453T1 (de)	1992-03-15	Flavon-derivate.
FI880939A7 (fi)	1988-09-03	Kromonijohdannaisia.
ATE126800T1 (de)	1995-09-15	Neplanocinderivate.
FI893278A7 (fi)	1990-01-07	N-fenylpyrazol-4-yleterderivat.
FI885046L (fi)	1989-05-05	Framstaellningsfoerfarande av ginkgolidderivat.
DE68911192D1 (de)	1994-01-20	Phosphonoalkylpurin-Derivate.
FI880814A7 (fi)	1988-09-11	Imidazodiazepin-derivat.
DE58903265D1 (de)	1993-02-25	Fluorcyclopropyl-derivate.
FI884960L (fi)	1989-05-01	Anvaendning av 2-pyrimidinyl-1-piperazin-derivat.
FI893041L (fi)	1989-06-21	Substituerade azacyklohexylderivat.
FI883555A7 (fi)	1989-01-30	Benzimidazolderivat.
FI893567L (fi)	1990-01-27	Foerfarande foer framstaellning av glykosfingolipidderivat.
DE68913856D1 (de)	1994-04-21	Cycloalkylthiazol-Derivate.
DE3785022D1 (de)	1993-04-29	Sicherheitssensoren.
FI881802L (fi)	1988-10-18	Tiadiazolylacetamidocefemderivat.
FI885920L (fi)	1989-06-23	Piperidinylcyklopentylheptensyra -derivat innehaollande vattenhaltiga sammansaettningar.