NO892136L - Fremgangsmaate for fremstilling av nye peptider. - Google Patents

Fremgangsmaate for fremstilling av nye peptider.

Info

Publication number
NO892136L
NO892136L NO89892136A NO892136A NO892136L NO 892136 L NO892136 L NO 892136L NO 89892136 A NO89892136 A NO 89892136A NO 892136 A NO892136 A NO 892136A NO 892136 L NO892136 L NO 892136L
Authority
NO
Norway
Prior art keywords
procedure
preparation
new peptides
peptides
new
Prior art date
Application number
NO89892136A
Other languages
English (en)
Norwegian (no)
Other versions
NO892136D0 (no
Inventor
Richard Himmelsbach
John Cooke Hodges
James Stanley Kaltenbronn
William Chester Patt
Joseph Thomas Repine
Ila Sircar
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of NO892136D0 publication Critical patent/NO892136D0/no
Publication of NO892136L publication Critical patent/NO892136L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/38Drugs for disorders of the endocrine system of the suprarenal hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO89892136A 1988-05-27 1989-05-26 Fremgangsmaate for fremstilling av nye peptider. NO892136L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19999088A 1988-05-27 1988-05-27
US07/321,638 US5036053A (en) 1988-05-27 1989-03-15 Diol-containing renin inhibitors

Publications (2)

Publication Number Publication Date
NO892136D0 NO892136D0 (no) 1989-05-26
NO892136L true NO892136L (no) 1989-11-28

Family

ID=26895354

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89892136A NO892136L (no) 1988-05-27 1989-05-26 Fremgangsmaate for fremstilling av nye peptider.

Country Status (11)

Country Link
US (1) US5036053A (fr)
EP (1) EP0343654A3 (fr)
JP (1) JPH0267297A (fr)
KR (1) KR900018137A (fr)
AU (1) AU625456B2 (fr)
DK (1) DK258589A (fr)
FI (1) FI892521A7 (fr)
NO (1) NO892136L (fr)
NZ (1) NZ229281A (fr)
PH (1) PH26816A (fr)
PT (1) PT90659B (fr)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
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ATE107658T1 (de) * 1988-01-26 1994-07-15 Sankyo Co Renin inhibierende polypeptide, ihre herstellung und anwendung.
US5238923A (en) * 1989-05-26 1993-08-24 Warner-Lambert Company Amino-substituted heterocycles as renin inhibitors
IE68045B1 (en) * 1990-05-11 1996-05-15 Abbott Lab Renin inhibitors
WO1993006127A1 (fr) * 1991-09-17 1993-04-01 Warner-Lambert Company Nouveaux inhibiteurs de renine a base de promedicaments a acides amines
EP0539976A1 (fr) * 1991-10-29 1993-05-05 G.D. Searle & Co. Dérivés d'éthynyl alanine amino diol pour le traitement de l'hypertension
US5227401A (en) * 1991-10-29 1993-07-13 G. D. Searle & Co. Ethynyl alanine amino diol compounds for treatment of hypertension
US5223535A (en) * 1991-10-29 1993-06-29 G. D. Searle & Co. Propargyl glycine amino propargyl diol compounds for treatment of hypertension
CA2127456A1 (fr) * 1992-02-13 1993-08-19 Warner-Lambert Company Llc Methode de preparation du compose chiral (5-amino-1,2-dihydro-2-methyl-3-phenylpyrido[3,4-b]pyrazin-7-yl)carbamate d'ethyle
US5972990A (en) * 1992-04-10 1999-10-26 Brigham And Women's Hospital, Inc. Methods for reducing risk of repeat myocardial infarction and increasing survival in heart attack victims
US5252591A (en) 1992-08-14 1993-10-12 G. D. Searle & Company Pyridinyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension
US5298505A (en) * 1992-08-14 1994-03-29 G. D. Searle & Co. Ethynyl alanine amino diol compounds having a piperazinyl-terminated group or a piperazinyl-alkylamino-terminated group for treatment of hypertension
US5373017A (en) * 1992-08-14 1994-12-13 G. D. Searle & Co. Imidazolyl/benzimidazolyl-terminated alkylamino ethynyl alanine amino diol compounds for treatment of hypertension
US6376506B1 (en) 1997-01-23 2002-04-23 Syntex (U.S.A.) Llc Sulfamide-metalloprotease inhibitors
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EP1012839A4 (fr) * 1997-04-30 2001-01-10 Spectra Logic Corp Systeme de bibliotheque a chargeur de donnees
US6423688B1 (en) * 1997-07-31 2002-07-23 Athena Neurosciences, Inc. Dipeptide and related compounds which inhibit leukocyte adhesion mediated by VLA-4
US6130220A (en) * 1997-10-16 2000-10-10 Syntex (Usa) Inc. Sulfamide-metalloprotease inhibitors
US6407124B1 (en) 1998-06-18 2002-06-18 Bristol-Myers Squibb Company Carbon substituted aminothiazole inhibitors of cyclin dependent kinases
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AU2002331753A1 (en) 2001-08-27 2003-03-10 The Research Foundation Of State University Of New York Dirhodium catalyst compositions and methods for using same
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WO2003095623A2 (fr) * 2002-05-10 2003-11-20 The Trustees Of Columbia University In The City Of New York Lignees cellulaires et systemes mis au point par genie genetique et destines a propager le virus varicelle-zona, et methodes d'utilisation associees
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ES2381551T3 (es) 2003-12-05 2012-05-29 The Cleveland Clinic Foundation Marcadores de riesgo para enfermedad cardiovascular
CA2554716A1 (fr) * 2004-01-22 2005-08-04 Nitromed, Inc. Composes nitroses et/ou nitrosyles, compositions et procede pour les utiliser
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US8067464B2 (en) 2004-10-04 2011-11-29 Nitromed, Inc. Compositions and methods using apocynin compounds and nitric oxide donors
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CA3189771A1 (fr) 2020-07-22 2022-01-27 Janssen Pharmaceutica Nv Composes utiles en tant qu'inhibiteurs du facteur xia
US11814364B2 (en) 2021-03-18 2023-11-14 Janssen Pharmaceutica Nv Pyridine N-oxide derivatives useful as factor XIa inhibitors
US11919881B2 (en) 2021-03-18 2024-03-05 Janssen Pharmaceutica Nv Substituted pyridine N-oxide derivatives useful as a factor XIa inhibitors
US11845748B2 (en) 2021-03-18 2023-12-19 Janssen Pharmaceutica Nv Bicyclic pyridine N-oxide derivatives useful as a factor XIa inhibitors
US11897880B2 (en) 2021-04-30 2024-02-13 Janssen Pharmaceutica Nv 7,8-dihydrobenzo[e]pyrido[3,4-c]azocine-2,5(3H,6H)-dione derivatives useful as a factor XIa inhibitors
US11958856B2 (en) 2021-07-22 2024-04-16 Janssen Pharmaceutica Nv Substituted 1,2,3,8,9,9a-hexahydro-5H-pyrrolo[1,2-a]azepin-5-ones as factor XIa inhibitors
US12286429B2 (en) 2021-07-22 2025-04-29 Janssen Pharmaceutica Nv 5-oxo-1,2,3,5,8,8a-hexahydroindolizine-3-carboxamide derivatives useful as a factor XIa inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4845079A (en) * 1985-01-23 1989-07-04 Luly Jay R Peptidylaminodiols
EP0249096B1 (fr) * 1986-06-10 1995-01-11 Merck Patent Gmbh Dérivés d'acides aminés inhibant la rénine.

Also Published As

Publication number Publication date
EP0343654A3 (fr) 1991-05-29
FI892521A0 (fi) 1989-05-24
DK258589A (da) 1989-11-28
AU3463389A (en) 1989-11-30
AU625456B2 (en) 1992-07-09
EP0343654A2 (fr) 1989-11-29
PH26816A (en) 1992-11-05
NZ229281A (en) 1991-11-26
KR900018137A (ko) 1990-12-20
US5036053A (en) 1991-07-30
PT90659B (pt) 1994-10-31
DK258589D0 (da) 1989-05-26
JPH0267297A (ja) 1990-03-07
FI892521L (fi) 1989-11-28
PT90659A (pt) 1989-11-30
FI892521A7 (fi) 1989-11-28
NO892136D0 (no) 1989-05-26

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