NO892679L - Fremgangsmaate for fremstilling av 19-fluor- eller cyano- 21-hydroxyprogesteronderivater. - Google Patents

Fremgangsmaate for fremstilling av 19-fluor- eller cyano- 21-hydroxyprogesteronderivater.

Info

Publication number: NO892679L
Authority: NO; Norway
Prior art keywords: fluoro; cyano; undertives; hydroxyprogester; procedure
Prior art date: 1988-06-28

Application number

NO89892679A

Other languages

English (en)

Norwegian (no)

Other versions

NO892679D0 (no

Inventor

Gene Warwick Holbert

John O'neal Johnston

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-06-28

Filing date

1989-06-27

Publication date

1989-12-29

1989-06-27 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1989-06-27 Publication of NO892679D0 publication Critical patent/NO892679D0/no

1989-12-29 Publication of NO892679L publication Critical patent/NO892679L/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
- C07J5/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa not substituted in position 16
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Steroid Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Manufacture Of Macromolecular Shaped Articles (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Organic Insulating Materials (AREA)

NO89892679A 1988-06-28 1989-06-27 Fremgangsmaate for fremstilling av 19-fluor- eller cyano- 21-hydroxyprogesteronderivater. NO892679L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/212,410 US4920114A (en)	1988-06-28	1988-06-28	19-fluoro- or cyano-21-hydroxyprogesterone derivatives useful as 19-hydroxylase inhibitors

Publications (2)

Publication Number	Publication Date
NO892679D0 NO892679D0 (no)	1989-06-27
NO892679L true NO892679L (no)	1989-12-29

Family

ID=22790899

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO89892679A NO892679L (no)	1988-06-28	1989-06-27	Fremgangsmaate for fremstilling av 19-fluor- eller cyano- 21-hydroxyprogesteronderivater.

Country Status (19)

Country	Link
US (1)	US4920114A (de)
EP (1)	EP0348911B1 (de)
JP (1)	JP2727466B2 (de)
KR (1)	KR0140885B1 (de)
CN (1)	CN1039424A (de)
AT (1)	ATE100462T1 (de)
AU (1)	AU610413B2 (de)
CA (1)	CA1321579C (de)
DE (1)	DE68912422T2 (de)
DK (1)	DK318489A (de)
ES (1)	ES2061802T3 (de)
FI (1)	FI893162A7 (de)
HU (1)	HUT51289A (de)
IL (1)	IL90728A0 (de)
NO (1)	NO892679L (de)
NZ (1)	NZ229694A (de)
PH (1)	PH25771A (de)
PT (1)	PT90989B (de)
ZA (1)	ZA894753B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4433374A1 (de) *	1994-09-20	1996-03-21	Hoechst Ag	17-Desoxi-corticosteroid-21-/O/-Carbonsäure- ester, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US6787530B1 (en)	1996-08-23	2004-09-07	Monash University	Use of pregnane-diones as analgesic agents

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3124574A (en) *		1964-03-10		Iz-halo pregnenes
US3154569A (en) *	1961-10-10	1964-10-27	Vismara Francesco Spa	19-nitrilosteroids and process for producing 19-norsteroids
IT1051705B (it) *	1962-05-12	1981-05-20	Vismara Spa F	Metodo per la preparazione di intermedi steroidali
GB984093A (en) *	1962-02-19	1965-02-24	Syntex Corp	Improvements in or relating to 19-halo-pregnane compounds
US3257389A (en) *	1962-09-21	1966-06-21	Syntex Corp	19-bisdifluoro-pregnanes
US3257435A (en) *	1962-09-21	1966-06-21	Syntex Corp	19-bisdifluoro pregnanes
US3205228A (en) *	1963-03-01	1965-09-07	Syntex Corp	19-substituted pregnenes
US3159620A (en) *	1963-05-22	1964-12-01	Vismara Francesco Spa	Process for the preparation of 17 alpha-ethynyl-19-norandrostene compounds
US3394128A (en) *	1964-09-26	1968-07-23	Syntex Corp	19-halo-androstane and pregnane derivatives and processes for the preparation thereof
FR2462445A1 (fr) *	1979-07-31	1981-02-13	Roussel Uclaf	Nouveaux derives 17-/(hydroxymethyl) (formamido) methylene/steroides, leur procede de preparation et leur application a l'introduction de la chaine laterale hydroxyacetyle
US4293548A (en) *	1980-09-02	1981-10-06	Merrell Dow Pharmaceuticals Inc.	18-Substituted pregn-4-ene-3,20-diones

1988
- 1988-06-28 US US07/212,410 patent/US4920114A/en not_active Expired - Lifetime
1989
- 1989-06-22 ZA ZA894753A patent/ZA894753B/xx unknown
- 1989-06-23 NZ NZ229694A patent/NZ229694A/en unknown
- 1989-06-23 IL IL90728A patent/IL90728A0/xx not_active IP Right Cessation
- 1989-06-26 KR KR1019890008781A patent/KR0140885B1/ko not_active Expired - Fee Related
- 1989-06-27 PT PT90989A patent/PT90989B/pt not_active IP Right Cessation
- 1989-06-27 AT AT89111699T patent/ATE100462T1/de not_active IP Right Cessation
- 1989-06-27 CA CA000604022A patent/CA1321579C/en not_active Expired - Lifetime
- 1989-06-27 PH PH38862A patent/PH25771A/en unknown
- 1989-06-27 ES ES89111699T patent/ES2061802T3/es not_active Expired - Lifetime
- 1989-06-27 CN CN89106339A patent/CN1039424A/zh active Pending
- 1989-06-27 HU HU893242A patent/HUT51289A/hu unknown
- 1989-06-27 DE DE68912422T patent/DE68912422T2/de not_active Expired - Lifetime
- 1989-06-27 NO NO89892679A patent/NO892679L/no unknown
- 1989-06-27 DK DK318489A patent/DK318489A/da not_active Application Discontinuation
- 1989-06-27 JP JP1162845A patent/JP2727466B2/ja not_active Expired - Lifetime
- 1989-06-27 EP EP89111699A patent/EP0348911B1/de not_active Expired - Lifetime
- 1989-06-28 AU AU37126/89A patent/AU610413B2/en not_active Ceased
- 1989-06-28 FI FI893162A patent/FI893162A7/fi not_active Application Discontinuation

Also Published As

Publication number	Publication date
EP0348911A2 (de)	1990-01-03
FI893162L (fi)	1989-12-29
US4920114A (en)	1990-04-24
EP0348911B1 (de)	1994-01-19
CA1321579C (en)	1993-08-24
DK318489A (da)	1989-12-29
JP2727466B2 (ja)	1998-03-11
JPH0248597A (ja)	1990-02-19
DK318489D0 (da)	1989-06-27
ES2061802T3 (es)	1994-12-16
AU610413B2 (en)	1991-05-16
FI893162A7 (fi)	1989-12-29
CN1039424A (zh)	1990-02-07
PT90989B (pt)	1994-11-30
PH25771A (en)	1991-10-18
ATE100462T1 (de)	1994-02-15
PT90989A (pt)	1989-12-29
FI893162A0 (fi)	1989-06-28
HUT51289A (en)	1990-04-28
IL90728A0 (en)	1990-01-18
NO892679D0 (no)	1989-06-27
KR0140885B1 (ko)	1998-06-15
DE68912422D1 (de)	1994-03-03
ZA894753B (en)	1990-03-28
KR900000321A (ko)	1990-01-30
NZ229694A (en)	1992-03-26
EP0348911A3 (en)	1990-03-28
DE68912422T2 (de)	1994-08-18
AU3712689A (en)	1990-01-04

Publication	Publication Date	Title
NO914092D0 (no)	1991-10-17	Fremgangsmaate for fremstilling av mercaptoacetylamidderivater
NO895086L (no)	1990-06-25	Fremgangsmaate for fremstilling av terapeutisk aktive heterocykliske forbindelser.
NO892936D0 (no)	1989-07-17	Fremgangsmaate for fremstilling av furanderivater.
NO161497C (no)	1989-08-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive 9a-aza-9a-homoerytromycin-derivater.
AU610473B2 (en)	1991-05-16	19-substituted progesterone derivatives useful as 19-hydroxylase inhibitors
NO890969L (no)	1989-09-11	Fremgangsmaate for fremstilling av isoindolinderivater.
FI884984A7 (fi)	1989-05-01	Menetelmä metyylitritioyhdisteiden kohdennettujen johdannaisten valmistamiseksi
DK250689D0 (da)	1989-05-23	Fremgangsmaade til fremstilling af napthalenderivater
NO872463D0 (no)	1987-06-12	Fremgangsmaate for fremstilling av dihydropyridinderivater med antihypertensiv virkning.
NO892204L (no)	1989-12-04	Fremgangsmaate for fremstilling av imidazokinoxalin-forbindelser.
NO891588D0 (no)	1989-04-18	Fremgangsmaate for fremstilling av fosfonoalkylpurinderivater.
NO892679D0 (no)	1989-06-27	Fremgangsmaate for fremstilling av 19-fluor- eller cyano- 21-hydroxyprogesteronderivater.
DK143889A (da)	1989-09-27	Fremgangsmaade til fremstilling af naphthalenderivater
NO894707L (no)	1990-05-28	Fremgangsmaate for fremstilling av benzoksazinderivater.
EE9400304A (et)	1996-04-15	Nukleosiididerivaatide valmistamise meetod ja selle meetodiga saadud ühendid
NO892813L (no)	1990-01-15	Fremgangsmaate til fremstilling av l-alanyl-l-prolin-derivater.
NO903254D0 (no)	1990-07-20	Fremgangsmaate for fremstilling av kinuklidin-derivater.
NO163404C (no)	1990-05-23	Analogifremgangsmaate for fremstilling av terapeutisk aktive benzokinolizin-derivater.