NO894086L - Fremgangsmaate for fremstilling av piperidinylbenzimidazoler. - Google Patents

Fremgangsmaate for fremstilling av piperidinylbenzimidazoler.

Info

Publication number: NO894086L
Authority: NO; Norway
Prior art keywords: procedure; benzimidazoles; piperidinyl; piperidinyl benzimidazoles
Prior art date: 1988-10-13

Application number

NO89894086A

Other languages

English (en)

Norwegian (no)

Other versions

NO894086D0 (no

Inventor

Albert Anthony Carr

John Michael Kane

Hsien Cheng Cheng

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-10-13

Filing date

1989-10-12

Publication date

1990-04-17

1989-10-12 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1989-10-12 Publication of NO894086D0 publication Critical patent/NO894086D0/no

1990-04-17 Publication of NO894086L publication Critical patent/NO894086L/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Pulmonology (AREA)
Immunology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

NO89894086A 1988-10-13 1989-10-12 Fremgangsmaate for fremstilling av piperidinylbenzimidazoler. NO894086L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/256,959 US4908372A (en)	1988-10-13	1988-10-13	Antihistaminic piperidinyl benzimidazoles

Publications (2)

Publication Number	Publication Date
NO894086D0 NO894086D0 (no)	1989-10-12
NO894086L true NO894086L (no)	1990-04-17

Family

ID=22974308

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO89894086A NO894086L (no)	1988-10-13	1989-10-12	Fremgangsmaate for fremstilling av piperidinylbenzimidazoler.

Country Status (20)

Country	Link
US (1)	US4908372A (de)
EP (1)	EP0363963B1 (de)
JP (1)	JP2867151B2 (de)
KR (1)	KR0157046B1 (de)
CN (1)	CN1028103C (de)
AR (1)	AR248018A1 (de)
AT (1)	ATE121741T1 (de)
AU (1)	AU619601B2 (de)
CA (1)	CA2000468C (de)
DE (1)	DE68922366T2 (de)
DK (1)	DK506189A (de)
ES (1)	ES2074067T3 (de)
FI (1)	FI894834A7 (de)
HU (1)	HU203340B (de)
IE (1)	IE66112B1 (de)
IL (1)	IL91952A (de)
NO (1)	NO894086L (de)
NZ (1)	NZ230956A (de)
PT (1)	PT91968B (de)
ZA (1)	ZA897676B (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2022451C (en) *	1989-08-03	2001-01-23	Albert Anthony Carr	Anti-psychotic piperidynl benzimidazole compounds
AU8506791A (en) *	1990-10-01	1992-04-28	Janssen Pharmaceutica N.V.	Novel 4-piperidinylcarbonyl derivatives
FR2668150B1 (fr) *	1990-10-17	1994-11-18	Theramex	Nouveaux derives du terbutylphenyl 1-amino 4-hydroxybutane, leurs procedes de preparation et les compositions pharmaceutiques en renfermant.
CA2097317C (en) *	1990-12-14	2002-02-12	Albert A. Carr	Antiallergic piperdinyl benzimidazoles
TW263504B (de) *	1991-10-03	1995-11-21	Pfizer
TW231291B (de) *	1992-01-09	1994-10-01	Janssen Pharmaceutica Nv
NZ249286A (en) *	1992-02-13	1996-02-27	Merrell Dow Pharma	Piperidine-4-ylmethyl thiophene and thiazole derivatives and pharmaceutical compositions
CA2198084C (en)	1994-08-25	2000-03-28	Timothy P. Burkholder	Novel substituted piperidines useful for the treatment of allergic diseases
US6211199B1 (en)	1995-11-17	2001-04-03	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl-amino)piperidines useful for the treatment of allergic diseases
US6194406B1 (en)	1995-12-20	2001-02-27	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
US6423704B2 (en)	1995-12-20	2002-07-23	Aventis Pharmaceuticals Inc.	Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
US5998439A (en)	1996-02-21	1999-12-07	Hoescht Marion Roussel, Inc.	Substituted N-methyl-N-(4-(piperidin-1-yl)-2-(aryl)butyl)benzamides useful for the treatment of allergic diseases
US5922737A (en) *	1996-02-21	1999-07-13	Hoechst Marion Roussel, Inc.	Substituted N-methyl-N-(4-(4-(1H-Benzimidazol-2-YL-amino) piperidin-1-YL)-2-(arlyl) butyl) benzamides useful for the treatment of allergic diseases
US5932571A (en) *	1996-02-21	1999-08-03	Hoechst Marion Roussel, Inc.	Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
AU724646B2 (en) *	1996-03-15	2000-09-28	Eli Lilly And Company	Method of treating common cold or allergic rhinitis
US5869497A (en) *	1996-03-15	1999-02-09	Eli Lilly And Company	Method of treating or ameliorating the symptoms of common cold or allergic rhinitis
US7166617B2 (en) *	2000-02-29	2007-01-23	Mitsubishi Pharma Corporation	Cyclic amide derivatives
TW200517114A (en)	2003-10-15	2005-06-01	Combinatorx Inc	Methods and reagents for the treatment of immunoinflammatory disorders
BRPI0516132A (pt) *	2004-10-07	2007-12-04	Vitae Pharmaceuticals Inc	compostos, composição destes, método de antagonização de uma ou mais proteases aspárticas e método para tratar ou melhorar um distúrbio mediado por protease aspártica
JP2009514969A (ja)	2005-11-09	2009-04-09	コンビナトアールエックスインコーポレーティッド	医学的状態を治療するための方法、組成物、およびキット
TWI411607B (zh) *	2005-11-14	2013-10-11	Vitae Pharmaceuticals Inc	天門冬胺酸蛋白酶抑制劑
US20090318501A1 (en) *	2006-09-18	2009-12-24	Baldwin John J	Piperidine derivatives as renin inhibitors
CL2007002689A1 (es) *	2006-09-18	2008-04-18	Vitae Pharmaceuticals Inc	Compuestos derivados de piperidin-1-carboxamida, inhibidores de la renina; compuestos intermediarios; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como hipertension, insuficiencia cardiaca, fibrosis cardiaca, entre otras.
EP2170815A2 (de) *	2007-06-20	2010-04-07	Vitae Pharmaceuticals, Inc.	Renininhibitoren
WO2009096996A1 (en) *	2007-06-20	2009-08-06	Smithkline Beecham Corporation	Renin inhibitors
EP2307396A1 (de) *	2008-06-20	2011-04-13	Vitae Pharmaceuticals, Inc.	Renininhibitoren und verfahren zu deren anwendung
CA2729052A1 (en) *	2008-06-26	2009-12-30	Vitae Pharmaceuticals, Inc.	Salts of methyl 2-((r)-(3-chlorophenyl)((r)-1-((s)-2-(methylamino)-3((r)-tetrahydro-2h-pyran-3-yl)propylcarbamoyl)piperidin-3-yl)methoxy)ethylcarbamate
US20100092479A1 (en) *	2008-08-18	2010-04-15	Combinatorx (Singapore) Pte. Ltd.	Compositions and methods for treatment of viral diseases
AR077692A1 (es) *	2009-08-06	2011-09-14	Vitae Pharmaceuticals Inc	Sales de 2-((r)-(3-clorofenil) ((r)-1-((s) -2-(metilamino)-3-((r)-tetrahidro-2h-piran-3-il) propilcarbamoil) piperidin -3-il) metoxi) etilcarbamato de metilo
US20110130711A1 (en) *	2009-11-19	2011-06-02	Follica, Inc.	Hair growth treatment
EP2447263A1 (de)	2010-09-27	2012-05-02	Bioprojet	Benzazolderivate als Histamin-H4-Rezeptorliganden
BR112014030940B1 (pt)	2012-06-11	2022-09-06	UCB Biopharma SRL	Benzimidazóis que modulam tnf-alfa e composição farmacêutica compreendendo os mesmos
GB201510758D0 (en)	2015-06-18	2015-08-05	Ucb Biopharma Sprl	Novel TNFa structure for use in therapy
GB201621907D0 (en)	2016-12-21	2017-02-01	Ucb Biopharma Sprl And Sanofi	Antibody epitope

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3878217A (en) *	1972-01-28	1975-04-15	Richardson Merrell Inc	Alpha-aryl-4-substituted piperidinoalkanol derivatives
US4219559A (en) *	1979-01-10	1980-08-26	Janssen Pharmaceutica N.V.	N-Heterocyclyl-4-piperidinamines
US4285957A (en) *	1979-04-10	1981-08-25	Richardson-Merrell Inc.	1-Piperidine-alkanol derivatives, pharmaceutical compositions thereof, and method of use thereof
US4254129A (en) *	1979-04-10	1981-03-03	Richardson-Merrell Inc.	Piperidine derivatives
US4695575A (en) *	1984-11-13	1987-09-22	Janssen Pharmaceutica, N.V.	4-[(bicycle heterocyclyl)-methyl and -hetero]-piperidines
PH23995A (en) *	1984-01-09	1990-02-09	Janssen Pharmaceutica Nv	4((bicycle heterocyclyl)-methyl and hetero)piperidines
CA2022451C (en) *	1989-08-03	2001-01-23	Albert Anthony Carr	Anti-psychotic piperidynl benzimidazole compounds

1988
- 1988-10-13 US US07/256,959 patent/US4908372A/en not_active Expired - Lifetime
1989
- 1989-10-09 AR AR89315117A patent/AR248018A1/es active
- 1989-10-09 ZA ZA897676A patent/ZA897676B/xx unknown
- 1989-10-10 AU AU42735/89A patent/AU619601B2/en not_active Ceased
- 1989-10-10 NZ NZ230956A patent/NZ230956A/en unknown
- 1989-10-11 CA CA002000468A patent/CA2000468C/en not_active Expired - Fee Related
- 1989-10-11 IL IL9195289A patent/IL91952A/en not_active IP Right Cessation
- 1989-10-11 KR KR1019890014536A patent/KR0157046B1/ko not_active Expired - Fee Related
- 1989-10-12 AT AT89118987T patent/ATE121741T1/de not_active IP Right Cessation
- 1989-10-12 ES ES89118987T patent/ES2074067T3/es not_active Expired - Lifetime
- 1989-10-12 IE IE329489A patent/IE66112B1/en not_active IP Right Cessation
- 1989-10-12 CN CN89107837A patent/CN1028103C/zh not_active Expired - Fee Related
- 1989-10-12 DE DE68922366T patent/DE68922366T2/de not_active Expired - Fee Related
- 1989-10-12 NO NO89894086A patent/NO894086L/no unknown
- 1989-10-12 EP EP89118987A patent/EP0363963B1/de not_active Expired - Lifetime
- 1989-10-12 PT PT91968A patent/PT91968B/pt not_active IP Right Cessation
- 1989-10-12 DK DK506189A patent/DK506189A/da not_active Application Discontinuation
- 1989-10-12 HU HU895305A patent/HU203340B/hu not_active IP Right Cessation
- 1989-10-12 FI FI894834A patent/FI894834A7/fi not_active Application Discontinuation
- 1989-10-13 JP JP1267959A patent/JP2867151B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IL91952A0 (en)	1990-06-10
AU4273589A (en)	1990-04-26
NZ230956A (en)	1991-03-26
US4908372A (en)	1990-03-13
CA2000468C (en)	2000-03-21
KR0157046B1 (ko)	1998-11-16
CN1041940A (zh)	1990-05-09
HU895305D0 (en)	1990-01-28
IE66112B1 (en)	1995-12-13
CA2000468A1 (en)	1990-04-13
ATE121741T1 (de)	1995-05-15
DK506189A (da)	1990-04-14
KR900006318A (ko)	1990-05-07
AR248018A1 (es)	1995-05-31
FI894834A7 (fi)	1990-04-14
FI894834A0 (fi)	1989-10-12
AU619601B2 (en)	1992-01-30
JPH02134377A (ja)	1990-05-23
ZA897676B (en)	1990-07-25
DE68922366T2 (de)	1995-09-28
NO894086D0 (no)	1989-10-12
IL91952A (en)	1994-06-24
DE68922366D1 (de)	1995-06-01
HU203340B (en)	1991-07-29
ES2074067T3 (es)	1995-09-01
JP2867151B2 (ja)	1999-03-08
EP0363963B1 (de)	1995-04-26
IE893294L (en)	1990-04-13
HUT51613A (en)	1990-05-28
DK506189D0 (da)	1989-10-12
PT91968B (pt)	1995-05-31
PT91968A (pt)	1990-04-30
CN1028103C (zh)	1995-04-05
EP0363963A1 (de)	1990-04-18

Publication	Publication Date	Title
NO894086L (no)	1990-04-17	Fremgangsmaate for fremstilling av piperidinylbenzimidazoler.
NO903190L (no)	1991-01-21	Fremgangsmaate for klorering av sukrose-b-estere.
DE3781845D1 (de)	1992-10-29	Benzimidazol-derivate.
NL300161I2 (nl)	2005-02-01	Carbostyrilderivaten.
FI890866A7 (fi)	1989-08-24	Piperidinderivat.
NO872831D0 (no)	1987-07-07	Fremgangsmaate for fremstilling av nitrofuranderivater.
ATE124397T1 (de)	1995-07-15	Piperidin-derivate.
DE3768992D1 (de)	1991-05-08	Benzimidazol-derivate.
NO890579D0 (no)	1989-02-10	((5(6) (1h-azol-1-ylmetyl)benzimidazol)karbamater.
FI885243A0 (fi)	1988-11-11	Foerfarande foer framstaellning av stabiliserade olefinpolymerer.
DE58906668D1 (de)	1994-02-24	Spannzange.
FI902336A0 (fi)	1990-05-10	Anordning foer framstaellning av en fristaoende kiselkristall.
FI892761A0 (fi)	1989-06-06	Expressionsvektorer foer framstaellning av ofusionerade proteiner i mikroorganismer.
FI891124A0 (fi)	1989-03-09	Anordning foer framstaellning av en flerskiktstraeskiva.
FI883555A7 (fi)	1989-01-30	Benzimidazolderivat.
FI894582A0 (fi)	1989-09-27	Borranordning foer framstaellning av borrhaol med bakskaerning.
FI895021A0 (fi)	1989-10-23	Anordning foer utfoerande av membransepareringsprocesser.
FI890717L (fi)	1989-09-18	Foerfarande foer framstaellning av (r)-glycidylestrar.
DE58901804D1 (de)	1992-08-13	Spannzange.
NO892714L (no)	1990-01-02	Substituerte azacykloheksylderivater.
NO892006D0 (no)	1989-05-19	Anordning for dannelse av oppstaaende kant.
FI862656A0 (fi)	1986-06-23	Anordning foer defibrering av smaelt mineralmaterial.
FI881824A7 (fi)	1988-10-22	Dihydropyridiinijohdannaiset.
FI891507L (fi)	1989-10-21	Staell foer solfaongare.
FI882557A0 (fi)	1988-05-31	Anordning foer smoerjning av en kuggvaexel.