NO894811L - Vandig doxorubicinloesning. - Google Patents

Vandig doxorubicinloesning.

Info

Publication number
NO894811L
NO894811L NO89894811A NO894811A NO894811L NO 894811 L NO894811 L NO 894811L NO 89894811 A NO89894811 A NO 89894811A NO 894811 A NO894811 A NO 894811A NO 894811 L NO894811 L NO 894811L
Authority
NO
Norway
Prior art keywords
solution
doxorubicin
approx
doxorubic
physiologically acceptable
Prior art date
Application number
NO89894811A
Other languages
English (en)
Other versions
NO894811D0 (no
Inventor
Murray A Kaplan
Robert K Perrone
Joseph B Bogardus
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO894811D0 publication Critical patent/NO894811D0/no
Publication of NO894811L publication Critical patent/NO894811L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Lubricants (AREA)
  • Lubrication Of Internal Combustion Engines (AREA)

Abstract

Det fremstilles stabile, klar-til-bruk vandige løsninger av doxorubicin inneholdende et fysiologisk akseptabelt salt av doxorubicin, natriumacetonbisulfitt som antioksidant, vann og, om nødvendig en tilstrekkelig mengde av en fysiologisk akseptabel syre eller base til justering av løsningens pH-verdi til innenfor et område på ca. 2,5 til ca. 6,0. Løsningene har en akseptabel lagertid på mere enn 3 år ved 4°C.
NO89894811A 1988-12-05 1989-12-01 Vandig doxorubicinloesning. NO894811L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27962788A 1988-12-05 1988-12-05

Publications (2)

Publication Number Publication Date
NO894811D0 NO894811D0 (no) 1989-12-01
NO894811L true NO894811L (no) 1990-06-06

Family

ID=23069771

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89894811A NO894811L (no) 1988-12-05 1989-12-01 Vandig doxorubicinloesning.

Country Status (20)

Country Link
EP (1) EP0372888B1 (no)
JP (1) JPH02200637A (no)
KR (1) KR920001460B1 (no)
AT (1) ATE78402T1 (no)
AU (1) AU612916B2 (no)
DD (1) DD295990A5 (no)
DE (1) DE68902223T2 (no)
DK (1) DK609889A (no)
ES (1) ES2044148T3 (no)
FI (1) FI895733A7 (no)
GR (1) GR3005391T3 (no)
HU (1) HU204704B (no)
IE (1) IE893867L (no)
IL (1) IL92541A0 (no)
NO (1) NO894811L (no)
NZ (1) NZ231602A (no)
OA (1) OA09898A (no)
PT (1) PT92483B (no)
YU (1) YU226189A (no)
ZA (1) ZA899248B (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006213440A1 (en) * 2005-02-11 2006-08-17 Dabur Pharma Limited Stabilized anthracycline glycoside pharmaceutical compositions
EP3417864A4 (en) * 2016-02-16 2019-08-21 General Incorporated Association Pharma Valley Project Supporting Organisation IMMUNOSUPPRESSION TENDERING AGENT AND USE THEREOF

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8519452D0 (en) * 1985-08-02 1985-09-11 Erba Farmitalia Injectable solutions
FI883338A7 (fi) * 1987-07-16 1989-01-17 Bristol Myers Squibb Co Doksorubisiinihydrokloridin vesiliuoksia

Also Published As

Publication number Publication date
PT92483B (pt) 1995-08-09
DE68902223D1 (de) 1992-08-27
JPH02200637A (ja) 1990-08-08
DK609889D0 (da) 1989-12-04
HU204704B (en) 1992-02-28
ATE78402T1 (de) 1992-08-15
NZ231602A (en) 1991-12-23
DD295990A5 (de) 1991-11-21
HU896426D0 (en) 1990-02-28
AU612916B2 (en) 1991-07-18
IL92541A0 (en) 1990-08-31
DK609889A (da) 1990-06-06
OA09898A (fr) 1994-09-15
KR920001460B1 (ko) 1992-02-14
GR3005391T3 (no) 1993-05-24
KR900009081A (ko) 1990-07-02
NO894811D0 (no) 1989-12-01
YU226189A (en) 1991-02-28
AU4591589A (en) 1990-06-07
FI895733A7 (fi) 1990-06-06
DE68902223T2 (de) 1993-01-14
EP0372888B1 (en) 1992-07-22
IE893867L (en) 1990-06-05
FI895733A0 (fi) 1989-11-30
ES2044148T3 (es) 1994-01-01
PT92483A (pt) 1990-06-29
ZA899248B (en) 1990-08-29
HUT52961A (en) 1990-09-28
EP0372888A1 (en) 1990-06-13

Similar Documents

Publication Publication Date Title
IT1200589B (it) Derivati naturali attivita farmagologica
NO149232C (no) Sporicid, perkarboksylsyreholdig desinfeksjonsmiddel i form av en alkoholisk eller vandig alkoholisk opploesning
DK379481A (da) Phosphotsyremonoestersalte deres fremstilling og anvendelse som fungicider
DK540581A (da) 5,5!-azobis-salicylsyresalte deres fremstilling og anvendelse til bekaempelse af tarmbetaendelse
DE3870064D1 (de) Waessrige loesungen von doxorubicinhydrochlorid.
DK364682A (da) Substituerede azolylphenoxyderivater, deres fremstilling og anvendelse som fungicider
DK570488D0 (da) Substituerede azolylmethylcarbinoler, deres fremstilling og anvendelse som fungicider og plantevaekstregulatorer
DK617186A (da) Antioxidationsforbindelser og fremstilling og anvendelse deraf
ES2002124A6 (es) Solucion acuosa estabilizada de peroxido de hidrogeno y metodo para su preparacion
ATE78402T1 (de) Waesserige loesungen von doxorubicin.
DK301580A (da) N,n-dimethyl-o-pyrimidinyl-carminsyreestere fremgangsmaader til deres fremstilling og deres anvendelse som skadedyrebekaempeelsesmidler
NO893525D0 (no) Amidoaminsalter av alkenylravsyrederivater, fremgangsmaater for deres fremstilling og deres anvendelse som korrosjonsinhibitorer.
DK302678A (da) N,n-dial-0-pyrimidinyl-carbaminsyreestere fremgangsmaade til deres fremstilling og deres anvendelse som insecticider
DK88985D0 (da) Aminodiarylsulfoxidderivater og syreadditionssalte deraf, deres anvendelse som farmaceutika og pesticider
DK179986D0 (da) Racemiske og optisk aktive 1,12b-disubstituerede octahydroindolo(2,3-a)quinolizinderivater eller cis- og trans-isomere eller syreadditionssalte deraf, deres fremstilling og anvendelse som farmaceutika, mellemprodukter ved fremstillingen og disses fremstilling
DK48385A (da) N-substituerede aminopropansulfonsyrederivater eller hydrater og salte deraf, deres fremstilling og anvendelse som plantevaekstregulatorer
NO972303L (no) Intravenöse lubeluzollösninger
DK123986D0 (da) 2-chlor-ethyl-phosphonsyre-estere og plantevaekstregulerende midler, der indeholder saadanne som aktive bestanddele
DK208687D0 (da) Substituerede quinoxalinyloxy-phenoxypropionsyre-derivater, deres fremstilling og anvendelse som herbicide midler
DK94885A (da) Substituerede phenoxypropionsyre-derivater, deres fremstilling og anvendelse som herbicider
DK216985A (da) Sulfenylerede carbamidsyreestere, deres fremstilling og anvendelse som mikrobiocide midler