NO894995L - Fremgangsmaate for fremstilling av terapeutisk aktive anionebytter-polymerer. - Google Patents

Fremgangsmaate for fremstilling av terapeutisk aktive anionebytter-polymerer.

Info

Publication number
NO894995L
NO894995L NO89894995A NO894995A NO894995L NO 894995 L NO894995 L NO 894995L NO 89894995 A NO89894995 A NO 89894995A NO 894995 A NO894995 A NO 894995A NO 894995 L NO894995 L NO 894995L
Authority
NO
Norway
Prior art keywords
procedure
preparation
anion exchange
therapeutic active
exchange polymers
Prior art date
Application number
NO89894995A
Other languages
English (en)
Norwegian (no)
Other versions
NO894995D0 (no
Inventor
Albert Andrzej Jaxa-Chamiec
Deirdre Mary Bernadette Hickey
David Alston
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of NO894995D0 publication Critical patent/NO894995D0/no
Publication of NO894995L publication Critical patent/NO894995L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F265/00Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00
    • C08F265/04Macromolecular compounds obtained by polymerising monomers on to polymers of unsaturated monocarboxylic acids or derivatives thereof as defined in group C08F20/00 on to polymers of esters
    • C08F265/06Polymerisation of acrylate or methacrylate esters on to polymers thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/03Preparation of carboxylic acid esters by reacting an ester group with a hydroxy group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62Halogen-containing esters
    • C07C69/65Halogen-containing esters of unsaturated acids
    • C07C69/653Acrylic acid esters; Methacrylic acid esters; Haloacrylic acid esters; Halomethacrylic acid esters
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08FMACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00Chemical modification by after-treatment
    • C08F8/44Preparation of metal salts or ammonium salts

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Electrically Driven Valve-Operating Means (AREA)
  • Piezo-Electric Or Mechanical Vibrators, Or Delay Or Filter Circuits (AREA)
  • Liquid Crystal (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
NO89894995A 1988-12-13 1989-12-12 Fremgangsmaate for fremstilling av terapeutisk aktive anionebytter-polymerer. NO894995L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888829088A GB8829088D0 (en) 1988-12-13 1988-12-13 Compounds

Publications (2)

Publication Number Publication Date
NO894995D0 NO894995D0 (no) 1989-12-12
NO894995L true NO894995L (no) 1990-06-14

Family

ID=10648421

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89894995A NO894995L (no) 1988-12-13 1989-12-12 Fremgangsmaate for fremstilling av terapeutisk aktive anionebytter-polymerer.

Country Status (21)

Country Link
US (1) US5441731A (ja)
EP (1) EP0373852B1 (ja)
JP (1) JPH02212505A (ja)
KR (1) KR900009725A (ja)
CN (1) CN1044105A (ja)
AT (1) ATE113299T1 (ja)
AU (1) AU620183B2 (ja)
CA (1) CA2004706A1 (ja)
DE (1) DE68919061T2 (ja)
DK (1) DK621289A (ja)
ES (1) ES2063829T3 (ja)
FI (1) FI895936A7 (ja)
GB (1) GB8829088D0 (ja)
HU (1) HU209397B (ja)
IE (1) IE893966L (ja)
MY (1) MY105079A (ja)
NO (1) NO894995L (ja)
NZ (1) NZ231728A (ja)
PT (1) PT92531B (ja)
ZA (1) ZA899467B (ja)
ZW (1) ZW16589A1 (ja)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69328741T2 (de) * 1992-01-14 2000-09-07 Hisamitsu Pharmaceutical Co., Inc. Unvernetztes Anion-Austauscherharz und diesen enthaltende pharmazeutische Zusammensetzung
US5556619A (en) * 1992-08-20 1996-09-17 The Du Pont Merck Pharmaceutical Company Crosslinked polymeric ammonium salts
US5900475A (en) * 1994-06-10 1999-05-04 Geltex Pharmaceuticals, Inc. Hydrophobic sequestrant for cholesterol depletion
AU7047994A (en) * 1993-06-02 1994-12-20 Geltex Pharmaceuticals, Inc. Compositions and process for removing bile salts
US5929184A (en) * 1993-06-02 1999-07-27 Geltex Pharmaceuticals, Inc. Hydrophilic nonamine-containing and amine-containing copolymers and their use as bile acid sequestrants
US5703188A (en) * 1993-06-02 1997-12-30 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US5607669A (en) * 1994-06-10 1997-03-04 Geltex Pharmaceuticals, Inc. Amine polymer sequestrant and method of cholesterol depletion
US5618530A (en) * 1994-06-10 1997-04-08 Geltex Pharmaceuticals, Inc. Hydrophobic amine polymer sequestrant and method of cholesterol depletion
US5624963A (en) * 1993-06-02 1997-04-29 Geltex Pharmaceuticals, Inc. Process for removing bile salts from a patient and compositions therefor
US6129910A (en) * 1993-06-02 2000-10-10 Geltex Pharmaceuticals, Inc. Water-insoluble noncrosslinked bile acid sequestrants
MX9602812A (es) * 1994-01-18 1997-06-28 Du Pont Sales de amonio polimericas, reticuladas.
US6936277B2 (en) * 1995-01-09 2005-08-30 J. Rettenmaier & Soehne Gmbh & Co. Kg Pharmaceutical excipient having improved compressibility
US6471994B1 (en) 1995-01-09 2002-10-29 Edward Mendell Co., Inc. Pharmaceutical excipient having improved compressibility
US6395303B1 (en) 1996-06-10 2002-05-28 Edward Mendell Co., Inc. Process for preparing a directly compressible solid dosage form containing microcrystalline cellulose
US5948438A (en) * 1995-01-09 1999-09-07 Edward Mendell Co., Inc. Pharmaceutical formulations having improved disintegration and/or absorptivity
US5585115A (en) 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability
IL116674A (en) * 1995-01-09 2003-05-29 Mendell Co Inc Edward Microcrystalline cellulose-based excipient having improved compressibility, pharmaceutical compositions containing the same and methods for the preparation of said excipient and of solid dosage form thereof
US6203785B1 (en) 1996-12-30 2001-03-20 Geltex Pharmaceuticals, Inc. Poly(diallylamine)-based bile acid sequestrants
US5936003A (en) * 1997-03-03 1999-08-10 Dionex Corporation Hydrolytically stable resins for use in anion-exchange chromatography
US6423754B1 (en) 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
KR100381512B1 (ko) * 2000-09-21 2003-04-26 굿젠 주식회사 유전자 및 생물학적 활성 약물 전달용 양이온성 지질과이의 용도
US7385012B2 (en) 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7459502B2 (en) 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7767768B2 (en) 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7449605B2 (en) 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7608674B2 (en) 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
PT2184059E (pt) 2004-03-30 2012-07-06 Relypsa Inc Polímeros de ligação a ião e seus usos
BRPI0509331B8 (pt) 2004-03-30 2021-05-25 Ilypsa Inc uso de uma composição de ligação de sódio
GB2446077B (en) 2005-09-30 2010-10-13 Ilypsa Inc Methods and compositions for selectively removing potassium ion from the gastrointestinal tract of a mammal
CA2624112A1 (en) 2005-09-30 2007-04-05 Ilypsa, Inc. Methods for preparing core-shell composites having cross-linked shells and core-shell composites resulting therefrom
MX389664B (es) 2008-08-22 2025-03-20 Vifor Int Ltd Polimeros reticulados de intercambio cationico, composiciones y su uso en el tratamiento de la hipercalcemia

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2843573A (en) * 1955-03-21 1958-07-15 Rohm & Haas New quaternary ammonium compounds in which the nitrogen atom carries an alkoxymethyl group
DE1065181B (de) * 1956-11-28 1959-09-10 Rohm S. Haas Company, Philadelphia, Pa. (V. St. A.) Verfahren zur Herstellung eines sowohl schwachbasischen anionenadsorbierenden, als auch stark-basischen, quaternäre Ammoniumgruppen enthaltenden Anionenaustauscherharzes
DE1233604B (de) * 1961-09-08 1967-02-02 Du Pont Verfahren zur Herstellung Aminoxydgruppen enthaltender Mischpolymerisate
BE756035A (fr) * 1969-09-12 1971-03-11 Inveresk Res Int Polymeres pontes
GB1309496A (en) * 1970-05-20 1973-03-14 Mitsubishi Gas Chemical Co Process for producing cationic synthetic latex
CS171962B1 (ja) * 1974-02-01 1976-11-29
JPS50110482A (ja) * 1974-02-13 1975-08-30
JPS52127995A (en) * 1976-04-19 1977-10-27 Johnson & Johnson Hydrophilic random copolymers composition and process for producing same
US4393145A (en) * 1979-05-01 1983-07-12 Etablissement Texcontor Anionic ion exchange resins with cholesterol-decreasing properties
JPS58154709A (ja) * 1982-03-09 1983-09-14 Kyoritsu Yuki Kogyo Kenkyusho:Kk カチオン性高吸水性樹脂の製法
DE3587419T2 (de) * 1985-01-07 1993-12-16 Rhone Poulenc Spec Chim Karboxylgruppenhaltige Polymere, Verfahren zu deren Herstellung und ihre Verwendung.
US4621120A (en) * 1985-04-01 1986-11-04 Eastman Kodak Company Polymeric antibacterial compositions
JPH075683B2 (ja) * 1986-09-09 1995-01-25 三菱レイヨン株式会社 帯電防止性に優れたメタクリル樹脂キヤスト板の製造方法
US4981936A (en) * 1989-04-14 1991-01-01 Polypure, Inc. Terpolymer of oxyalkyene acrylates, acrylamides and quaternary monomers

Also Published As

Publication number Publication date
DE68919061D1 (de) 1994-12-01
DK621289D0 (da) 1989-12-08
KR900009725A (ko) 1990-07-05
ES2063829T3 (es) 1995-01-16
AU4608089A (en) 1990-06-21
DK621289A (da) 1990-06-14
NZ231728A (en) 1992-03-26
GB8829088D0 (en) 1989-01-25
DE68919061T2 (de) 1995-04-06
ZW16589A1 (en) 1990-10-10
FI895936A0 (fi) 1989-12-12
HUT53135A (en) 1990-09-28
MY105079A (en) 1994-07-30
CN1044105A (zh) 1990-07-25
FI895936A7 (fi) 1990-06-14
CA2004706A1 (en) 1990-06-13
EP0373852A2 (en) 1990-06-20
PT92531B (pt) 1995-08-09
IE893966L (en) 1990-06-13
NO894995D0 (no) 1989-12-12
HU896510D0 (en) 1990-02-28
AU620183B2 (en) 1992-02-13
EP0373852A3 (en) 1991-12-27
JPH02212505A (ja) 1990-08-23
ATE113299T1 (de) 1994-11-15
ZA899467B (en) 1991-07-31
HU209397B (en) 1994-05-30
US5441731A (en) 1995-08-15
EP0373852B1 (en) 1994-10-26
PT92531A (pt) 1990-06-29

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