ATE46517T1 - Diacylderivate von glycerylphosphorylcholin mit therapeutischen eigenschaften, verfahren zu ihrer herstellung und entsprechende pharmazeutische zusammensetzungen. - Google Patents

Diacylderivate von glycerylphosphorylcholin mit therapeutischen eigenschaften, verfahren zu ihrer herstellung und entsprechende pharmazeutische zusammensetzungen.

Info

Publication number
ATE46517T1
ATE46517T1 AT85115414T AT85115414T ATE46517T1 AT E46517 T1 ATE46517 T1 AT E46517T1 AT 85115414 T AT85115414 T AT 85115414T AT 85115414 T AT85115414 T AT 85115414T AT E46517 T1 ATE46517 T1 AT E46517T1
Authority
AT
Austria
Prior art keywords
glycerylphosphorylcholine
preparation
pharmaceutical compositions
therapeutic properties
respective pharmaceutical
Prior art date
Application number
AT85115414T
Other languages
English (en)
Inventor
Carlo Scolastico
Giovanni Tronconi
Original Assignee
Neopharmed Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neopharmed Spa filed Critical Neopharmed Spa
Application granted granted Critical
Publication of ATE46517T1 publication Critical patent/ATE46517T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/10Phosphatides, e.g. lecithin
    • C07F9/106Adducts, complexes, salts of phosphatides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/06Phosphorus compounds without P—C bonds
    • C07F9/08Esters of oxyacids of phosphorus
    • C07F9/09Esters of phosphoric acids
    • C07F9/091Esters of phosphoric acids with hydroxyalkyl compounds with further substituents on alkyl
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT85115414T 1984-12-05 1985-12-04 Diacylderivate von glycerylphosphorylcholin mit therapeutischen eigenschaften, verfahren zu ihrer herstellung und entsprechende pharmazeutische zusammensetzungen. ATE46517T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT23896/84A IT1178709B (it) 1984-12-05 1984-12-05 Diacilderivati della glicerilfosforilcolina ad attivita'terapeutica, procedimento per la loro preparazione e relative composizioni farmaceutiche
EP85115414A EP0186803B1 (de) 1984-12-05 1985-12-04 Diacylderivate von Glycerylphosphorylcholin mit therapeutischen Eigenschaften, Verfahren zu ihrer Herstellung und entsprechende pharmazeutische Zusammensetzungen

Publications (1)

Publication Number Publication Date
ATE46517T1 true ATE46517T1 (de) 1989-10-15

Family

ID=11210716

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85115414T ATE46517T1 (de) 1984-12-05 1985-12-04 Diacylderivate von glycerylphosphorylcholin mit therapeutischen eigenschaften, verfahren zu ihrer herstellung und entsprechende pharmazeutische zusammensetzungen.

Country Status (9)

Country Link
US (2) US4699901A (de)
EP (1) EP0186803B1 (de)
JP (1) JPS61171490A (de)
AT (1) ATE46517T1 (de)
CA (1) CA1300152C (de)
DE (1) DE3573121D1 (de)
ES (1) ES8606372A1 (de)
IT (1) IT1178709B (de)
PT (1) PT81621B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1178709B (it) * 1984-12-05 1987-09-16 Neopharmed Spa Diacilderivati della glicerilfosforilcolina ad attivita'terapeutica, procedimento per la loro preparazione e relative composizioni farmaceutiche
IT1201477B (it) * 1985-10-04 1989-02-02 Istituto Chemioterapico Procedimento per la preparazione di l-alfa-glicerilfosforilcolina,l-alfa-glicerilfosforiletanolommina e l-alfa-glicerilfosforilinositolo da lecitine grezze e/o deoleate
EP0329053A1 (de) * 1988-02-15 1989-08-23 MAGIS FARMACEUTICI S.p.A. Cholin-Ester-Glycerophosphorsäuren
IT1216535B (it) * 1988-03-28 1990-03-08 Magis Farmaceutici O_(1,2_di_0_acetilglicero_3_fosforil)etanolamina, procedimento per la sua preparazione e suo uso terapeutico.
JPH0745507B2 (ja) * 1988-06-02 1995-05-17 和光純薬工業株式会社 ホスファチジルコリン誘導体の製造方法
US4983592A (en) * 1988-12-19 1991-01-08 American Cyanamid Co. Bis-arylphosphate ester antagonists of platelet activating factor
US20110015154A1 (en) * 2009-07-20 2011-01-20 Kellermann Gottfried H Supporting acetylcholine function
US20110098265A1 (en) * 2009-10-28 2011-04-28 Neuroscience, Inc. Methods for reducing cravings and impulses associated with addictive and compulsive behaviors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2864848A (en) * 1954-07-19 1958-12-16 Ca Nat Research Council Method of producing l-alpha-glycerylphosphorylcholine
DK104583A (da) * 1982-03-22 1983-09-23 Fujisawa Pharmaceutical Co Fremgangsmaade til fremstilling af phospholipider
IT1178709B (it) * 1984-12-05 1987-09-16 Neopharmed Spa Diacilderivati della glicerilfosforilcolina ad attivita'terapeutica, procedimento per la loro preparazione e relative composizioni farmaceutiche

Also Published As

Publication number Publication date
IT1178709B (it) 1987-09-16
US4699901A (en) 1987-10-13
DE3573121D1 (en) 1989-10-26
IT8423896A1 (it) 1986-06-05
ES549645A0 (es) 1986-04-16
US4824978A (en) 1989-04-25
EP0186803A3 (en) 1987-06-16
JPS61171490A (ja) 1986-08-02
CA1300152C (en) 1992-05-05
PT81621B (pt) 1987-10-20
EP0186803A2 (de) 1986-07-09
PT81621A (en) 1986-01-02
ES8606372A1 (es) 1986-04-16
IT8423896A0 (it) 1984-12-05
EP0186803B1 (de) 1989-09-20

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee