NO904729L - Nye bakteriocinsammensetninger for anvendelse som bredspektrede baktericider og fremgangsmaater for forhindring og behandling av mikrobielle infeksjoner. - Google Patents
Nye bakteriocinsammensetninger for anvendelse som bredspektrede baktericider og fremgangsmaater for forhindring og behandling av mikrobielle infeksjoner.Info
- Publication number
- NO904729L NO904729L NO90904729A NO904729A NO904729L NO 904729 L NO904729 L NO 904729L NO 90904729 A NO90904729 A NO 90904729A NO 904729 A NO904729 A NO 904729A NO 904729 L NO904729 L NO 904729L
- Authority
- NO
- Norway
- Prior art keywords
- compositions
- bactericides
- lysostaphin
- broad range
- microbial infections
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 239000003899 bactericide agent Substances 0.000 title abstract 5
- 108010062877 Bacteriocins Proteins 0.000 title abstract 4
- 208000015181 infectious disease Diseases 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 230000000813 microbial effect Effects 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title 1
- 108090000988 Lysostaphin Proteins 0.000 abstract 4
- 230000000844 anti-bacterial effect Effects 0.000 abstract 4
- DWPCPZJAHOETAG-IMJSIDKUSA-N L-lanthionine Chemical compound OC(=O)[C@@H](N)CSC[C@H](N)C(O)=O DWPCPZJAHOETAG-IMJSIDKUSA-N 0.000 abstract 3
- DWPCPZJAHOETAG-UHFFFAOYSA-N meso-lanthionine Natural products OC(=O)C(N)CSCC(N)C(O)=O DWPCPZJAHOETAG-UHFFFAOYSA-N 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 239000002738 chelating agent Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- 241000295644 Staphylococcaceae Species 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
- A01N63/50—Isolated enzymes; Isolated proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Environmental Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Dentistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Agronomy & Crop Science (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Pest Control & Pesticides (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Saccharide Compounds (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/317,627 US4980163A (en) | 1989-03-01 | 1989-03-01 | Novel bacteriocin compositions for use as enhanced broad range bactericides and methods of preventing and treating microbial infection |
| PCT/US1990/001053 WO1990009739A1 (en) | 1989-03-01 | 1990-02-27 | Novel bacteriocin compositions for use as enhanced broad range bactericides and methods of preventing and treating microbial infection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO904729D0 NO904729D0 (no) | 1990-10-31 |
| NO904729L true NO904729L (no) | 1990-11-15 |
| NO304721B1 NO304721B1 (no) | 1999-02-08 |
Family
ID=23234535
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO904729A NO304721B1 (no) | 1989-03-01 | 1990-10-31 | Forsterket bredspektret baktericid sammensetning |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US4980163A (no) |
| EP (1) | EP0424484B1 (no) |
| JP (1) | JP2984744B2 (no) |
| KR (1) | KR0145738B1 (no) |
| AT (1) | ATE109624T1 (no) |
| AU (1) | AU618714B2 (no) |
| CA (1) | CA2028140C (no) |
| CZ (1) | CZ279273B6 (no) |
| DD (1) | DD301903A9 (no) |
| DE (1) | DE69011460T2 (no) |
| DK (1) | DK0424484T3 (no) |
| FI (1) | FI103861B (no) |
| HU (1) | HU217574B (no) |
| IE (1) | IE64710B1 (no) |
| IL (1) | IL93527A (no) |
| NO (1) | NO304721B1 (no) |
| NZ (1) | NZ232700A (no) |
| PL (1) | PL163940B1 (no) |
| RU (1) | RU2048151C1 (no) |
| WO (1) | WO1990009739A1 (no) |
| ZA (1) | ZA901499B (no) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5858962A (en) * | 1987-05-11 | 1999-01-12 | Ambi Inc. | Composition for treating mastitis and other staphylococcal infections |
| US5260271A (en) * | 1988-06-22 | 1993-11-09 | Applied Microbiology, Inc. | Nisin compositions for use as enhanced broad range bactericides |
| DE3938140A1 (de) * | 1989-11-16 | 1991-08-08 | Beiersdorf Ag | Desodorierende kosmetische mittel |
| NO911341L (no) * | 1990-04-20 | 1991-10-21 | Haarmann & Reimer Corp | Fremgangsmaate for aa drepe gram-negative bakterier. |
| WO1992018143A1 (en) * | 1991-04-15 | 1992-10-29 | Applied Microbiology, Inc. | Pharmaceutical compositions against gastric disorders |
| GB9126686D0 (en) * | 1991-12-17 | 1992-02-12 | Smithkline Beecham Plc | Novel compositions |
| US5342612A (en) * | 1991-12-20 | 1994-08-30 | American Cyanamid Company | Compositions for the treatment of mammalian diseases |
| DK0629347T3 (da) * | 1992-01-23 | 1998-02-16 | Morinaga Milk Industry Co Ltd | Antibakterielt middel og behandling af genstande dermed |
| DE4229707A1 (de) * | 1992-09-05 | 1994-03-10 | Beiersdorf Ag | Germicide Wirkstoffkombinationen |
| DE4307352A1 (de) * | 1992-10-29 | 1994-05-05 | Denecke Rainer Dr Med Vet | Präparat zur Therapie und insbesondere Prophylaxe von Erkrankungen des Verdauungstraktes |
| CA2148255A1 (en) * | 1992-10-29 | 1994-05-11 | Rainer Denecke | Preparation for therapeutic and especially prophylactic treatment of digestive tract disorders |
| GB9224598D0 (en) * | 1992-11-24 | 1993-01-13 | Smithkline Beecham Plc | Novel compositions |
| IL107887A (en) * | 1992-12-08 | 2003-07-06 | Ambi Inc | Stabilized lanthionine containing bacteriocin compositions |
| US5368845A (en) * | 1993-01-07 | 1994-11-29 | Colgate Palmolive Company | Oral composition |
| US5512269A (en) * | 1993-06-09 | 1996-04-30 | Burroughs Wellcome, Co. | Method of treating retained pulmonary secretions |
| ES2157985T3 (es) * | 1993-08-20 | 2001-09-01 | Novartis Ag | Metodo para la prevencion y el tratamiento de la mastitis bovina. |
| CA2121989A1 (en) * | 1993-11-18 | 1995-05-19 | Aloysius Knipper | Thermal abuse resistant egg |
| US5650320A (en) * | 1994-04-20 | 1997-07-22 | University Of Alabama At Birmingham Research Foundation | Lanthionine antibiotic compositions and methods |
| RU2143489C1 (ru) * | 1994-11-25 | 1999-12-27 | Нижегородский научно-исследовательский институт эпидемиологии и микробиологии | Способ получения лизостафина |
| US5762948A (en) * | 1995-06-07 | 1998-06-09 | Ambi Inc. | Moist bacteriocin disinfectant wipes and methods of using the same |
| CN1138560C (zh) * | 1995-06-23 | 2004-02-18 | Ambi股份有限公司 | 控制对抗生素耐药的革兰氏阳性细菌的方法和治疗感染的方法 |
| US5703040A (en) * | 1995-11-22 | 1997-12-30 | Kansas State University Research Foundation | Broad spectrum antibiotic peptide |
| US5804549A (en) * | 1996-01-05 | 1998-09-08 | Ambi Inc. | Compositions with activity against helicobacter |
| US6086894A (en) * | 1996-06-27 | 2000-07-11 | Virginia Tech Intellectual Properties, Inc. | Recombinant vaccine for diseases caused by encapsulated organisms |
| RU2203085C2 (ru) * | 1996-07-03 | 2003-04-27 | Элзэ Копэрейшн | Стабильный неводный препарат пептидного соединения, способ его получения и способ лечения гормон-зависимого заболевания у субъекта |
| US5916582A (en) * | 1996-07-03 | 1999-06-29 | Alza Corporation | Aqueous formulations of peptides |
| US5932547A (en) * | 1996-07-03 | 1999-08-03 | Alza Corporation | Non-aqueous polar aprotic peptide formulations |
| US5910479A (en) * | 1996-10-18 | 1999-06-08 | Ambi Inc. | Method for the treatment of Streptococcus pneumoniae infection |
| US6238377B1 (en) | 1997-01-27 | 2001-05-29 | Jin-Zhou Liu | Nasal-nasopharyngeal cleaning system |
| ZA984591B (en) * | 1997-06-09 | 1998-12-08 | Ambi Inc | A method for the treatment of diarrheal disease and for elmininating particular bacterial populations from the colon |
| US6028051A (en) * | 1997-07-23 | 2000-02-22 | Ambi Inc. | Method for the treatment of staphylococcal disease |
| US6315996B1 (en) | 1999-04-09 | 2001-11-13 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Topical lysostaphin therapy for staphylococcus ocular infections |
| US6187768B1 (en) | 1999-06-01 | 2001-02-13 | Becton, Dickinson And Company | Kit for flushing medical devices and method of preparation |
| US6342385B1 (en) | 2000-07-28 | 2002-01-29 | The Uab Research Foundation | Mutacin I biosynthesis genes and proteins |
| EP1362089B1 (en) * | 2001-02-17 | 2007-01-03 | Novozymes A/S | Reduction of malodour from laundry |
| US7572439B2 (en) * | 2002-03-26 | 2009-08-11 | Biosynexus Incorporated | Enzyme disruption of bacterial biofilms |
| RU2241339C2 (ru) * | 2002-09-19 | 2004-12-10 | Общество с ограниченной ответственностью "ЛЕНОК-М" | Способ производства консервов "зелёный горошек" из сушёного зерна |
| MXPA05004121A (es) * | 2002-10-18 | 2006-02-17 | Molichem Medicines Inc | Metodos para tratar la enfermedad de ojo reseco con lantibioticos. |
| AU2003296937A1 (en) * | 2002-12-10 | 2004-06-30 | Biosynexus Incorporated | Topical anti-infective formulations |
| US20100221237A1 (en) * | 2003-03-26 | 2010-09-02 | Biosynexus Incorporated | Enzyme disruption of bacterial biofilms |
| US6989370B2 (en) * | 2003-05-01 | 2006-01-24 | The United States Of America As Represented By The Secretary Of Agriculture | Bacteriocins and novel bacterial strains |
| DK1656026T3 (da) * | 2003-08-22 | 2014-07-14 | Dupont Nutrition Biosci Aps | Sammensætning, der omfatter et bakteriocin og et ekstrakt fra en plante fra læbeblomstfamilien |
| MXPA06002060A (es) * | 2003-08-22 | 2006-05-19 | Danisco | Composicion que comprende una bacteriocina y un extracto a partir de una planta de la familia labiatae. |
| US20050058673A1 (en) | 2003-09-09 | 2005-03-17 | 3M Innovative Properties Company | Antimicrobial compositions and methods |
| KR20070113281A (ko) | 2005-03-10 | 2007-11-28 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 항미생물성 조성물 및 방법 |
| EP1858506A2 (en) | 2005-03-10 | 2007-11-28 | 3M Innovative Properties Company | Methods of treating ear infections |
| EP3025704B1 (en) | 2005-03-10 | 2019-01-16 | 3M Innovative Properties Company | Methods of reducing microbial contamination |
| EP1959740A2 (en) * | 2005-11-15 | 2008-08-27 | LG Electronics Inc. | Antimicrobial coating based on kimchi lactic acid bacteria |
| ATE470451T1 (de) * | 2006-03-31 | 2010-06-15 | Univ St Andrews | Antimikrobielle zusammensetzungen mit einem kationischen peptid und glycylglycin- endopeptidase |
| WO2008137747A1 (en) * | 2007-05-02 | 2008-11-13 | The Regents Of The University Of Michigan | Nanoemulsion therapeutic compositions and methods of using the same |
| WO2009114520A2 (en) * | 2008-03-10 | 2009-09-17 | Pharmain Corporation | Compositions for treatment with metallopeptidases, methods of making and using the same |
| US20090304673A1 (en) * | 2008-06-10 | 2009-12-10 | Bernd Buchberger | Method of Treatment of Inflammatory Diseases |
| US8425968B2 (en) * | 2009-06-19 | 2013-04-23 | Pepsico., Inc. | Beverage preservative system containing pimaricin-cyclodextrin complex |
| US9200251B1 (en) | 2011-03-31 | 2015-12-01 | David Gordon Bermudes | Bacterial methionine analogue and methionine synthesis inhibitor anticancer, antiinfective and coronary heart disease protective microcins and methods of treatment therewith |
| US20140090833A1 (en) * | 2012-09-28 | 2014-04-03 | Halliburton Energy Services, Inc. | Methods for Treating Wellbore and Wellbore Operation Fluids |
| RU2629819C1 (ru) * | 2016-08-23 | 2017-09-04 | Федеральное бюджетное учреждение науки "Казанский научно-исследовательский институт эпидемиологии и микробиологии" Федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека | Антибактериальная композиция на основе хитозана и лизостафина |
| CN113396937A (zh) * | 2020-03-17 | 2021-09-17 | 孟州云大高科生物科技有限公司 | 一种多酶与生物类杀菌剂的组合物 |
| EP4146166A1 (en) | 2020-05-08 | 2023-03-15 | Fertin Pharma A/S | Mouthwash for oral care benefits |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2744827A (en) * | 1951-03-07 | 1956-05-08 | Nat Res Dev | Manufacture and preservation of cheese |
| GB738655A (en) * | 1952-05-09 | 1955-10-19 | Aplin & Barrett Ltd | A dry nisin preparation |
| US3278378A (en) | 1962-04-19 | 1966-10-11 | Schindler Charles Alvin | Staphylococcus-derived antibiotic |
| US3579354A (en) * | 1968-08-01 | 1971-05-18 | Beatrice Foods Co | Preparation of an elastic cheese product |
| US3899594A (en) * | 1971-09-13 | 1975-08-12 | Dirigo Corp | Food preservation |
| US3988307A (en) * | 1974-09-06 | 1976-10-26 | The United States Of America As Represented By The Secretary Of The Department Of Health, Education And Welfare | Solid phase synthesis of peptides with carboxyl-terminal amides |
| PL193146A1 (pl) * | 1976-10-19 | 1978-04-24 | Inst Przemyslu Mleczarskiego | Preparat enzymatyczny do dojrzewania bialkowych produktow mleczarskich |
| US4318928A (en) * | 1979-12-19 | 1982-03-09 | Sing Edmond L | Preparation of cottage cheese containing Streptococcus diacetilactis |
| US4477471A (en) * | 1982-04-15 | 1984-10-16 | Microlife Technics, Inc. | Preservation of foods with non-lactose fermenting Streptococcus Lactis subspecies diacetilactis |
| US4597972A (en) * | 1983-06-10 | 1986-07-01 | Aplin & Barrett, Ltd. | Nisin as an antibotulinal agent for food products |
| US4584199A (en) * | 1983-06-10 | 1986-04-22 | Aplin & Barrett, Ltd. | Antibotulinal agents for high moisture process cheese products |
| US4716115A (en) * | 1983-09-06 | 1987-12-29 | Microlife Technics, Inc. | Derived nisin producing microorganisms, method of production and use and products obtained thereby |
| US4485029A (en) * | 1984-03-19 | 1984-11-27 | Minnesota Mining And Manufacturing Company | Disinfecting method and compositions |
| US4929445A (en) * | 1988-01-25 | 1990-05-29 | Microlife Technics, Inc. | Method for inhibiting Listeria monocytogenes using a bacteriocin |
-
1989
- 1989-03-01 US US07/317,627 patent/US4980163A/en not_active Expired - Lifetime
-
1990
- 1990-02-26 IL IL9352790A patent/IL93527A/en not_active IP Right Cessation
- 1990-02-27 JP JP2504798A patent/JP2984744B2/ja not_active Expired - Lifetime
- 1990-02-27 EP EP90904988A patent/EP0424484B1/en not_active Expired - Lifetime
- 1990-02-27 AT AT90904988T patent/ATE109624T1/de not_active IP Right Cessation
- 1990-02-27 DE DE69011460T patent/DE69011460T2/de not_active Expired - Fee Related
- 1990-02-27 WO PCT/US1990/001053 patent/WO1990009739A1/en not_active Ceased
- 1990-02-27 KR KR1019900702363A patent/KR0145738B1/ko not_active Expired - Fee Related
- 1990-02-27 RU SU904831853A patent/RU2048151C1/ru not_active IP Right Cessation
- 1990-02-27 NZ NZ232700A patent/NZ232700A/en unknown
- 1990-02-27 HU HU849/90A patent/HU217574B/hu not_active IP Right Cessation
- 1990-02-27 CA CA002028140A patent/CA2028140C/en not_active Expired - Fee Related
- 1990-02-27 DK DK90904988.4T patent/DK0424484T3/da active
- 1990-02-27 AU AU52850/90A patent/AU618714B2/en not_active Ceased
- 1990-02-27 ZA ZA901499A patent/ZA901499B/xx unknown
- 1990-02-28 IE IE72190A patent/IE64710B1/en not_active IP Right Cessation
- 1990-03-01 DD DD33828290A patent/DD301903A9/de unknown
- 1990-03-01 PL PL90284095A patent/PL163940B1/pl not_active IP Right Cessation
- 1990-03-01 CZ CS90984A patent/CZ279273B6/cs not_active IP Right Cessation
- 1990-10-31 FI FI905378A patent/FI103861B/fi not_active IP Right Cessation
- 1990-10-31 NO NO904729A patent/NO304721B1/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU5285090A (en) | 1990-09-26 |
| DE69011460D1 (de) | 1994-09-15 |
| ATE109624T1 (de) | 1994-08-15 |
| IE900721L (en) | 1990-09-01 |
| IL93527A (en) | 1995-03-15 |
| CA2028140C (en) | 1996-12-03 |
| NO904729D0 (no) | 1990-10-31 |
| JPH03504864A (ja) | 1991-10-24 |
| NZ232700A (en) | 1992-10-28 |
| HU217574B (hu) | 2000-02-28 |
| FI103861B1 (fi) | 1999-10-15 |
| WO1990009739A1 (en) | 1990-09-07 |
| HUT55607A (en) | 1991-06-28 |
| FI905378A0 (fi) | 1990-10-31 |
| CA2028140A1 (en) | 1990-09-02 |
| KR0145738B1 (ko) | 1998-08-01 |
| PL163940B1 (pl) | 1994-05-31 |
| HU902849D0 (en) | 1991-05-28 |
| EP0424484A1 (en) | 1991-05-02 |
| ZA901499B (en) | 1990-11-28 |
| NO304721B1 (no) | 1999-02-08 |
| JP2984744B2 (ja) | 1999-11-29 |
| RU2048151C1 (ru) | 1995-11-20 |
| DK0424484T3 (da) | 1994-10-03 |
| PL284095A1 (en) | 1992-09-21 |
| AU618714B2 (en) | 1992-01-02 |
| CZ279273B6 (cs) | 1995-03-15 |
| IL93527A0 (en) | 1990-11-29 |
| EP0424484B1 (en) | 1994-08-10 |
| KR920700003A (ko) | 1992-02-19 |
| DD301903A9 (de) | 1994-06-30 |
| FI103861B (fi) | 1999-10-15 |
| IE64710B1 (en) | 1995-08-23 |
| DE69011460T2 (de) | 1994-12-22 |
| US4980163A (en) | 1990-12-25 |
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