NO911101L - Fremgangsmaate og mellomprodukter ved fremstilling av 2r-benzylchroman-6-karbaldehyd. - Google Patents

Fremgangsmaate og mellomprodukter ved fremstilling av 2r-benzylchroman-6-karbaldehyd.

Info

Publication number: NO911101L
Authority: NO; Norway
Prior art keywords: benzylchroman; carbaldehyde; chroman; procedure; preparation
Prior art date: 1990-03-21

Application number

NO91911101A

Other languages

English (en)

Other versions

NO911101D0 (no

NO179680C (no

NO179680B (no

Inventor

Frank John Urban

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-03-21

Filing date

1991-03-19

Publication date

1991-09-23

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23973911&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO911101(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1991-03-19 Application filed by Pfizer filed Critical Pfizer

1991-03-19 Publication of NO911101D0 publication Critical patent/NO911101D0/no

1991-09-23 Publication of NO911101L publication Critical patent/NO911101L/no

1996-08-19 Publication of NO179680B publication Critical patent/NO179680B/no

1996-11-27 Publication of NO179680C publication Critical patent/NO179680C/no

Links

239000013067 intermediate product Substances 0.000 title 1
VZWXIQHBIQLMPN-UHFFFAOYSA-N chromane Chemical compound C1=CC=C2CCCOC2=C1 VZWXIQHBIQLMPN-UHFFFAOYSA-N 0.000 abstract 2
125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
239000003472 antidiabetic agent Substances 0.000 abstract 1
239000003054 catalyst Substances 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
150000002148 esters Chemical class 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
229940126904 hypoglycaemic agent Drugs 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
108010079522 solysime Proteins 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/003—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions
- C12P41/004—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by ester formation, lactone formation or the inverse reactions by esterification of alcohol- or thiol groups in the enantiomers or the inverse reaction
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
- C07D311/66—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Wood Science & Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Biotechnology (AREA)
Analytical Chemistry (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
General Engineering & Computer Science (AREA)
Microbiology (AREA)
Genetics & Genomics (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

NO911101A 1990-03-21 1991-03-19 Fremgangsmåte ved fremstilling av 2R-benzylchroman-6-karbaldehyd NO179680C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/496,737 US5089637A (en)	1990-03-21	1990-03-21	Process and intermediates for 2r-benzyl-chroman-6-carbaldehyde

Publications (4)

Publication Number	Publication Date
NO911101D0 NO911101D0 (no)	1991-03-19
NO911101L true NO911101L (no)	1991-09-23
NO179680B NO179680B (no)	1996-08-19
NO179680C NO179680C (no)	1996-11-27

Family

ID=23973911

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO911101A NO179680C (no)	1990-03-21	1991-03-19	Fremgangsmåte ved fremstilling av 2R-benzylchroman-6-karbaldehyd

Country Status (20)

Country	Link
US (1)	US5089637A (no)
EP (1)	EP0448254B1 (no)
JP (1)	JPH0764838B2 (no)
KR (1)	KR940005601B1 (no)
AT (1)	ATE117299T1 (no)
AU (1)	AU620756B2 (no)
CA (1)	CA2038610C (no)
DE (1)	DE69106753T2 (no)
DK (1)	DK0448254T3 (no)
ES (1)	ES2067148T3 (no)
FI (1)	FI97385C (no)
GR (1)	GR3015390T3 (no)
HU (1)	HUT61603A (no)
IE (1)	IE64066B1 (no)
IL (1)	IL97549A0 (no)
MY (1)	MY106374A (no)
NO (1)	NO179680C (no)
NZ (1)	NZ237466A (no)
PT (1)	PT97070B (no)
ZA (1)	ZA912063B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5658796A (en) *	1995-06-07	1997-08-19	Seprachem, Inc.	Optical resolution of alkyl chroman-2-carboxylates
US6184005B1 (en)	1998-04-28	2001-02-06	Novo Nordisk A/S	Enzymatic resolvation for obtaining a (−)-3,4-trans-diarylchroman
JP2002512807A (ja) *	1998-04-28	2002-05-08	ノボノルディスクアクティーゼルスカブ	（−）−３．４−トランス−ジアリールクロマンを得るための酵素的分割
WO2003040382A1 (en) *	2001-11-09	2003-05-15	Kaneka Corporation	Process for producing optically active chroman derivative and intermediate
WO2004108944A1 (ja) *	2003-06-04	2004-12-16	Mitsubishi Gas Chemical Company, Inc.	光学活性クロマンカルボン酸エステルの製造方法
JP2008538576A (ja) *	2005-04-22	2008-10-30	ワイス	クロマンおよびクロメン誘導体およびその使用
KR100784850B1 (ko) *	2006-10-19	2007-12-14	충북대학교 산학협력단	크로만-2-카복실산 아릴아마이드 유도체, 그 제조방법 및이를 포함하는 ＮＦ-κＢ 저해제
IT1402974B1 (it)	2010-11-30	2013-09-27	Menarini Int Operations Lu Sa	Processo per la preparazione del nebivololo.
FR2986804A1 (fr) *	2012-02-09	2013-08-16	Servier Lab	Procede de synthese enzymatique de l'acide (7s) 3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene 7-carboxylique ou de ses esters, et application a la synthese de l'ivabradine et de ses sels
EP2968814B1 (en)	2013-03-15	2017-09-27	Airway Control Technologies, LLC	Medical breathing apparatus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4654362A (en) *	1983-12-05	1987-03-31	Janssen Pharmaceutica, N.V.	Derivatives of 2,2'-iminobisethanol
KR930005004B1 (ko) *	1985-04-15	1993-06-11	쟈안센 파아마슈우티카 엔. 부이.	치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법
WO1986007056A1 (en) *	1985-05-21	1986-12-04	Pfizer Inc.	Hypoglycemic thiazolidinediones
US5037747A (en) *	1988-01-26	1991-08-06	Hoffmann-La Roche Inc.	Production of benzopyran-2-carboxylic acids and esters by enzymatic hydrolysis

1990
- 1990-03-21 US US07/496,737 patent/US5089637A/en not_active Expired - Fee Related
1991
- 1991-03-07 AT AT91301891T patent/ATE117299T1/de not_active IP Right Cessation
- 1991-03-07 DE DE69106753T patent/DE69106753T2/de not_active Revoked
- 1991-03-07 ES ES91301891T patent/ES2067148T3/es not_active Expired - Lifetime
- 1991-03-07 EP EP91301891A patent/EP0448254B1/en not_active Revoked
- 1991-03-07 DK DK91301891.7T patent/DK0448254T3/da active
- 1991-03-14 IL IL97549A patent/IL97549A0/xx unknown
- 1991-03-18 NZ NZ237466A patent/NZ237466A/en unknown
- 1991-03-19 NO NO911101A patent/NO179680C/no not_active IP Right Cessation
- 1991-03-19 MY MYPI91000453A patent/MY106374A/en unknown
- 1991-03-19 PT PT97070A patent/PT97070B/pt not_active IP Right Cessation
- 1991-03-19 CA CA002038610A patent/CA2038610C/en not_active Expired - Fee Related
- 1991-03-20 JP JP3130827A patent/JPH0764838B2/ja not_active Expired - Fee Related
- 1991-03-20 ZA ZA912063A patent/ZA912063B/xx unknown
- 1991-03-20 HU HU91939A patent/HUT61603A/hu unknown
- 1991-03-20 KR KR1019910004388A patent/KR940005601B1/ko not_active Expired - Fee Related
- 1991-03-20 FI FI911356A patent/FI97385C/fi not_active IP Right Cessation
- 1991-03-20 AU AU73696/91A patent/AU620756B2/en not_active Ceased
- 1991-03-21 IE IE93891A patent/IE64066B1/en not_active IP Right Cessation
1995
- 1995-03-13 GR GR950400543T patent/GR3015390T3/el unknown

Also Published As

Publication number	Publication date
JPH04234871A (ja)	1992-08-24
JPH0764838B2 (ja)	1995-07-12
NO911101D0 (no)	1991-03-19
DE69106753D1 (de)	1995-03-02
DK0448254T3 (da)	1995-03-20
IE910938A1 (en)	1991-09-25
GR3015390T3 (en)	1995-06-30
DE69106753T2 (de)	1995-05-18
FI911356A0 (fi)	1991-03-20
EP0448254B1 (en)	1995-01-18
AU620756B2 (en)	1992-02-20
IL97549A0 (en)	1992-06-21
ATE117299T1 (de)	1995-02-15
FI97385C (fi)	1996-12-10
NO179680C (no)	1996-11-27
PT97070B (pt)	2001-05-31
MY106374A (en)	1995-05-30
EP0448254A3 (en)	1991-12-18
US5089637A (en)	1992-02-18
KR940005601B1 (ko)	1994-06-21
NO179680B (no)	1996-08-19
EP0448254A2 (en)	1991-09-25
HUT61603A (en)	1993-01-28
CA2038610C (en)	1999-03-09
AU7369691A (en)	1991-11-14
ZA912063B (en)	1992-10-28
ES2067148T3 (es)	1995-03-16
FI97385B (fi)	1996-08-30
NZ237466A (en)	1992-04-28
PT97070A (pt)	1991-10-31
KR910016939A (ko)	1991-11-05
IE64066B1 (en)	1995-07-12
HU910939D0 (en)	1991-10-28
FI911356L (fi)	1991-09-22
CA2038610A1 (en)	1991-09-22

Legal Events

Date	Code	Title	Description
2004-12-27	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
YU214290A (sh)	1992-12-21	Enzimsko razdvajanje endo-biciklo /2.2.1/heptan-2-ola i dobijanje optički aktivnih jedinjenja
NO911101D0 (no)	1991-03-19	Fremgangsmaate og mellomprodukter ved fremstilling av 2r-benzylchroman-6-karbaldehyd.
ATE70832T1 (de)	1992-01-15	Verfahren zur herstellung von 2-(4-fluorphenyl)alpha-methyl-5-benzoxazolessigs\|ure.
ATE9225T1 (de)	1984-09-15	Derivate des 5-hydroxy-tetrahydro-2-furanons.
SE9000790D0 (sv)	1990-03-06	Mellanprodukter vid stereokontrollerat acetoxi-azetidinon-foerfarande
FI853183A0 (fi)	1985-08-19	Foerfarande foer produktion av asymmetriska hydantoiner.
AU585703B2 (en)	1989-06-22	Process for the enzymatic resolution of racemic 2-amino- 1-alkanols
DK3889A (da)	1989-01-05	Optisk aktive propandiolderivater
ES2051767T3 (es)	1994-07-01	Cetorreduccion estereoespecifica de esteres de acido carboxilico-biciclooctanodiona por microorganismos.
DE69123009D1 (de)	1996-12-12	Verfahren zur Herstellung optisch aktiver 3-Hydroxybutan-Derivate
ES2055122T3 (es)	1994-08-16	Procedimiento de preparacion de acidos 2-ariloxi- o 2-ariltio-alcanoicos.
ATE1553T1 (de)	1982-09-15	Verfahren zur herstellung von penizillinderivaten.
DE60013325D1 (de)	2004-09-30	Stereospezifische hydrolyse von optisch aktiven estern
DE69123402D1 (de)	1997-01-16	Verfahren zur Herstellung optisch aktiver Alpha-Hydroxyalkenderivate
ES2140384T3 (es)	2000-03-01	Intermedios para 1-carbacefalosporinas y procedimiento para su preparacion.
UA11669A1 (uk)	1996-12-25	Стимулятор росту сіяhців сосhи звичайhої