NO922603L - Nye benzomorfoner og deres anvendelse som legemiddel - Google Patents

Nye benzomorfoner og deres anvendelse som legemiddel

Info

Publication number: NO922603L
Authority: NO; Norway
Prior art keywords: alkyl; new; benzomorphones; medicine; acyl
Prior art date: 1991-07-02

Application number

NO92922603A

Other languages

English (en)

Other versions

NO178263C (no

NO922603D0 (no

NO178263B (no

Inventor

Adrian Carter

Helmut Ensinger

Matthias Grauert

Franz Joseph Kuhn

Herbert Merz

Enzio Mueller

Werner Stransky

Ilse Streller

Original Assignee

Boehringer Ingelheim Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-02

Filing date

1992-07-01

Publication date

1993-01-04

1992-07-01 Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg

1992-07-01 Publication of NO922603D0 publication Critical patent/NO922603D0/no

1993-01-04 Publication of NO922603L publication Critical patent/NO922603L/no

1995-11-13 Publication of NO178263B publication Critical patent/NO178263B/no

1996-02-21 Publication of NO178263C publication Critical patent/NO178263C/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/26—Benzomorphans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Cardiology (AREA)
Psychiatry (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Pain & Pain Management (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

NO922603A 1991-07-02 1992-07-01 Nye benzomorfaner og deres anvendelse som legemiddel NO178263C (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE4121821A DE4121821A1 (de)	1991-07-02	1991-07-02	Neue benzomorphane und ihre verwendung als arzneimittel

Publications (4)

Publication Number	Publication Date
NO922603D0 NO922603D0 (no)	1992-07-01
NO922603L true NO922603L (no)	1993-01-04
NO178263B NO178263B (no)	1995-11-13
NO178263C NO178263C (no)	1996-02-21

Family

ID=6435223

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO922603A NO178263C (no)	1991-07-02	1992-07-01	Nye benzomorfaner og deres anvendelse som legemiddel

Country Status (24)

Country	Link
EP (1)	EP0521422B1 (no)
JP (1)	JP3324785B2 (no)
KR (1)	KR100251256B1 (no)
AT (1)	ATE137749T1 (no)
AU (1)	AU657330B2 (no)
CA (1)	CA2072814C (no)
CZ (1)	CZ286949B6 (no)
DE (2)	DE4121821A1 (no)
DK (1)	DK0521422T3 (no)
ES (1)	ES2086585T3 (no)
FI (1)	FI105913B (no)
GR (1)	GR3020124T3 (no)
HK (1)	HK1003111A1 (no)
HU (1)	HU220873B1 (no)
IE (1)	IE74400B1 (no)
IL (1)	IL102361A (no)
MX (1)	MX9203845A (no)
NO (1)	NO178263C (no)
NZ (1)	NZ243388A (no)
PH (1)	PH31430A (no)
SG (1)	SG43001A1 (no)
SK (1)	SK280776B6 (no)
TW (1)	TW214547B (no)
ZA (1)	ZA924883B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19528472A1 (de) *	1995-08-03	1997-02-06	Boehringer Ingelheim Kg	Neues Verfahren zur Herstellung von Norbenzomorphan einer Zwischenstufe bei Herstellung von pharmazeutisch wertvollen Benzomorphanderivaten, insbesondere von (-)-(1R,5S,S"R)-3'-Hydroxy-2-(2-methoxypropyl-)-5,9,9-trimethyl-6,7 benzomorphan
DE19740110A1 (de) *	1997-09-12	1999-03-18	Boehringer Ingelheim Pharma	Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocin-10-ole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
JPH1196519A (ja) *	1997-09-17	1999-04-09	Alps Electric Co Ltd	スピンバルブ型薄膜素子およびその製造方法
US6136980A (en) *	1998-05-01	2000-10-24	Boehringer Ingelheim Kg	Method of preparing norbenzomorphane as an intermediate in the preparation of pharmaceutically useful benzomorphane derivatives, in particular (-)-(1R,5S,2"R)-3'-hydroxy-2-(2-methoxypropyl)-5,9,9-trimethyl-6,7-benzo morphane
DE19826365A1 (de) *	1998-06-12	1999-12-16	Gruenenthal Gmbh	Verwendung von Benzomorphanderivaten als Analgetikum
US6355652B1 (en)	1999-11-27	2002-03-12	Boehringer Ingelheim Pharma Kg	Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocines and their use as pharmaceutical compositions
DE19957156A1 (de) *	1999-11-27	2001-05-31	Boehringer Ingelheim Pharma	Substituierte 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine und ihre Verwendung als Arzneimittel
DE10204276A1 (de) *	2002-02-02	2003-08-07	Boehringer Ingelheim Pharma	N-Allyloxyethyl-1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine und ihre Verwendung als Arzneimittel
CA2486157C (en)	2002-05-17	2013-04-16	Jenken Biosciences, Inc.	Opioid and opioid-like compounds and uses thereof
US7501433B2 (en)	2002-05-17	2009-03-10	Jenken Biosciences, Inc.	Opioid and opioid-like compounds and uses thereof
US7923454B2 (en)	2002-05-17	2011-04-12	Jenken Biosciences, Inc.	Opioid and opioid-like compounds and uses thereof
US8017622B2 (en)	2003-05-16	2011-09-13	Jenken Biosciences, Inc.	Opioid and opioid-like compounds and uses thereof
TW200927115A (en) *	2007-11-16	2009-07-01	Boehringer Ingelheim Int	Aryl-and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use
WO2015097545A1 (en)	2013-12-26	2015-07-02	Purdue Pharma L.P.	Opioid receptor modulating oxabicyclo[2.2.2]octane morphinans

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL7804509A (nl) *	1978-04-26	1979-10-30	Acf Chemiefarma Nv	Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan.
DE2828039A1 (de) *	1978-06-26	1980-01-10	Boehringer Sohn Ingelheim	2-(2-alkoxyethyl)-2'-hydroxy-6,7-benzomorphane deren saeureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung
NL7907800A (nl) *	1979-10-23	1981-04-27	Acf Chemiefarma Nv	Nieuwe 6,7-benzomorfanderivaten en zuuradditiezouten daarvan, farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werkwijze voor het bereiden van deze verbindingen en de farmaceutische preparaten.

1991
- 1991-07-02 DE DE4121821A patent/DE4121821A1/de not_active Withdrawn
1992
- 1992-06-03 TW TW081104377A patent/TW214547B/zh not_active IP Right Cessation
- 1992-06-27 SG SG1996002082A patent/SG43001A1/en unknown
- 1992-06-27 DE DE59206212T patent/DE59206212D1/de not_active Expired - Lifetime
- 1992-06-27 DK DK92110923.7T patent/DK0521422T3/da active
- 1992-06-27 AT AT92110923T patent/ATE137749T1/de active
- 1992-06-27 EP EP92110923A patent/EP0521422B1/de not_active Expired - Lifetime
- 1992-06-27 ES ES92110923T patent/ES2086585T3/es not_active Expired - Lifetime
- 1992-06-30 CA CA002072814A patent/CA2072814C/en not_active Expired - Lifetime
- 1992-06-30 IL IL10236192A patent/IL102361A/xx not_active IP Right Cessation
- 1992-06-30 MX MX9203845A patent/MX9203845A/es unknown
- 1992-06-30 NZ NZ243388A patent/NZ243388A/en not_active IP Right Cessation
- 1992-06-30 AU AU18686/92A patent/AU657330B2/en not_active Expired
- 1992-07-01 NO NO922603A patent/NO178263C/no not_active IP Right Cessation
- 1992-07-01 ZA ZA924883A patent/ZA924883B/xx unknown
- 1992-07-01 FI FI923050A patent/FI105913B/fi not_active IP Right Cessation
- 1992-07-01 JP JP17447992A patent/JP3324785B2/ja not_active Expired - Lifetime
- 1992-07-01 IE IE922144A patent/IE74400B1/en not_active IP Right Cessation
- 1992-07-01 HU HU9202199A patent/HU220873B1/hu unknown
- 1992-07-01 KR KR1019920011664A patent/KR100251256B1/ko not_active Expired - Lifetime
- 1992-07-02 PH PH44606A patent/PH31430A/en unknown
- 1992-07-02 SK SK2075-92A patent/SK280776B6/sk not_active IP Right Cessation
- 1992-07-02 CZ CS19922075A patent/CZ286949B6/cs not_active IP Right Cessation
1996
- 1996-05-31 GR GR960401503T patent/GR3020124T3/el unknown
1998
- 1998-03-16 HK HK98102148A patent/HK1003111A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
JPH05201987A (ja)	1993-08-10
CZ286949B6 (cs)	2000-08-16
SK207592A3 (en)	1997-01-08
CA2072814C (en)	2003-09-23
PH31430A (en)	1998-11-03
IL102361A (en)	1997-02-18
FI105913B (fi)	2000-10-31
JP3324785B2 (ja)	2002-09-17
NO178263C (no)	1996-02-21
NZ243388A (en)	1994-11-25
ZA924883B (en)	1993-02-24
ATE137749T1 (de)	1996-05-15
CA2072814A1 (en)	1993-01-03
SG43001A1 (en)	1997-10-17
GR3020124T3 (en)	1996-08-31
KR100251256B1 (ko)	2000-05-01
MX9203845A (es)	1993-01-01
AU657330B2 (en)	1995-03-09
DE4121821A1 (de)	1993-01-14
CZ207592A3 (en)	1993-08-11
FI923050L (fi)	1993-01-03
DK0521422T3 (da)	1996-06-10
FI923050A0 (fi)	1992-07-01
HUT66410A (en)	1994-11-28
IL102361A0 (en)	1993-01-14
NO922603D0 (no)	1992-07-01
EP0521422B1 (de)	1996-05-08
ES2086585T3 (es)	1996-07-01
AU1868692A (en)	1993-01-07
IE74400B1 (en)	1997-07-30
KR930002321A (ko)	1993-02-22
HU9202199D0 (en)	1992-10-28
TW214547B (no)	1993-10-11
HU220873B1 (en)	2002-06-29
SK280776B6 (sk)	2000-07-11
IE922144A1 (en)	1993-01-13
HK1003111A1 (en)	1998-10-09
EP0521422A1 (de)	1993-01-07
NO178263B (no)	1995-11-13
DE59206212D1 (de)	1996-06-13

Legal Events

Date	Code	Title	Description
2012-07-16	MK1K	Patent expired

Publication	Publication Date	Title
NO922603L (no)	1993-01-04	Nye benzomorfoner og deres anvendelse som legemiddel
DE69420564D1 (de)	1999-10-14	Immunsuppressive und antiallergische verbindungen; z.b. n-(3-oxohexanoyl)-homoserinlacton
DK0920421T3 (da)	2003-03-10	Isoxazolinderivater anvendelige som antimikrobielle midler
HU9904389D0 (en)	2000-01-28	Pyridine carboxylic acid derivatives and their salts, antibacterial agent comrising the same
TNSN01011A1 (en)	2005-11-10	3-AMINOQUINAZOLIN-2,4-DIONE ANTIBACTERIAL AGENTS
NO912940D0 (no)	1991-07-29	Immunundertrykkende middel og fremgangsmaate for fremstilling av samme.
DK0671156T3 (da)	2002-02-04	Kosmetiske eller farmaceutiske præparater indeholdende liposomer
DE69231538D1 (de)	2000-11-30	Ringsubstituierte 2-Amino-1,2,3,4-tetrahydronaphtahline und 3-Aminochromane
CO5080791A1 (es)	2001-09-25	Derivados de la piperidina que tienen efectos sobre sistemas con serotonina
DK0722319T3 (da)	2003-04-14	Anthracyclinonderivater samt deres anvendelse ved amyloidose
NO933425L (no)	1993-10-25	Nye aktive forbindelser
DK1086096T3 (da)	2003-11-10	Benzamider med tetrahydrofuranyloxy-substituenter som inhibitorer af phosphodiesterase 4
UY25211A1 (es)	2000-12-29	Inhibidores de isoquinolinilguanidina uroquinasa
ATE135206T1 (de)	1996-03-15	Arylalkylamine und -amide mit krampflösender und nervenschützender wirkung
NO922934L (no)	1993-01-25	Cykloheksan- og tetrahydropyranderivater
TW333532B (en)	1998-06-11	Benzopyrans
PT873993E (pt)	2002-07-31	Novos compostos heterociclicos processo para a sua preparacao e as composicoes farmaceuticas que os contem
ES2068040T3 (es)	1995-04-01	Sales de 3-(cis-2,6-dimetilpiperidino)-sidnonimina.
ES2158809A1 (es)	2001-09-01	Nuevos derivados sulfonados como inhibidores de la ciclooxigenasa ii.
SE0004480D0 (sv)	2000-12-05	Novel compounds
SE0002330D0 (sv)	2000-06-20	Novel compounds
ES2056374T3 (es)	1994-10-01	Mejoras en compuestos quimicos.