NO923153L - Indol-derivater, deres fremstilling og bruk - Google Patents

Indol-derivater, deres fremstilling og bruk

Info

Publication number
NO923153L
NO923153L NO92923153A NO923153A NO923153L NO 923153 L NO923153 L NO 923153L NO 92923153 A NO92923153 A NO 92923153A NO 923153 A NO923153 A NO 923153A NO 923153 L NO923153 L NO 923153L
Authority
NO
Norway
Prior art keywords
straight
branched
hydrogen
carbon atoms
preparation
Prior art date
Application number
NO92923153A
Other languages
English (en)
Other versions
NO923153D0 (no
Inventor
Lone Jeppesen
Peter Hoengaard Andersen
Louis Brammer Hansen
Peter Faarup
John Bondo Hansen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of NO923153L publication Critical patent/NO923153L/no
Publication of NO923153D0 publication Critical patent/NO923153D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Luminescent Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Indol-derivater med den generelle formel (I) (I) hvor R R2, 3 4 R og R kan være hydrogen eller lavere alkyl eventuelt substituert med halogen; A1 betyr en rett eller forgrenet alkylenkjede inneholdende fra 2 til 4 karbonatomer; R er hydrogen eller en rett eller forgrenet alkylgruppe; A er en rett eller forgrenet, mettet eller umettet hydro- karbonkjede inneholdende fra 2 til 6 karbonatomer; og R6 er valgt fra en gruppe bestående av forskjellige strukturer, er funnet å oppvise sentralnervesystem-aktivitet.
NO923153A 1990-02-13 1992-08-12 Indol-derivater, deres fremstilling og bruk NO923153D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK037790A DK37790A (da) 1990-02-13 1990-02-13 Indolderivater, deres fremstilling og anvendelse
PCT/DK1991/000041 WO1991012252A1 (en) 1990-02-13 1991-02-13 Indole derivatives, their preparation and use

Publications (2)

Publication Number Publication Date
NO923153L true NO923153L (no) 1992-08-12
NO923153D0 NO923153D0 (no) 1992-08-12

Family

ID=8092812

Family Applications (1)

Application Number Title Priority Date Filing Date
NO923153A NO923153D0 (no) 1990-02-13 1992-08-12 Indol-derivater, deres fremstilling og bruk

Country Status (16)

Country Link
US (1) US5126363A (no)
EP (1) EP0515462B1 (no)
JP (1) JPH05503525A (no)
AT (1) ATE123283T1 (no)
AU (1) AU641482B2 (no)
CA (1) CA2074727A1 (no)
DE (1) DE69110124T2 (no)
DK (2) DK37790A (no)
FI (1) FI923492L (no)
IE (1) IE69761B1 (no)
IL (1) IL97105A (no)
NO (1) NO923153D0 (no)
NZ (1) NZ237066A (no)
PT (1) PT96757B (no)
WO (1) WO1991012252A1 (no)
ZA (1) ZA91886B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2807577B2 (ja) * 1990-06-15 1998-10-08 エーザイ株式会社 環状アミド誘導体
ATE227718T1 (de) * 1998-04-08 2002-11-15 Wyeth Corp N-aryloxyethyl-indolyl-alkylamine zur behandlung von depressionen
US6162803A (en) * 1998-04-08 2000-12-19 American Home Products Corp. Indol-3-yl-cyclohexyl amine derivatives for the treatment of depression
US6150533A (en) * 1998-04-08 2000-11-21 American Home Products Corp. N-aryloxyethyl-indoly-alkylamines for the treatment of depression
JP2002510682A (ja) * 1998-04-08 2002-04-09 アメリカン・ホーム・プロダクツ・コーポレイション うつ病治療用のインドール−３−イル−シクロヘキシルアミン誘導体（５−ｈｔ１受容体拮抗薬）
WO2005023767A2 (en) 2003-09-10 2005-03-17 Brentwood Equities Ltd. Diastereomers of 4-aryloxy-3-hydroxypiperidines
US20100135851A1 (en) * 2008-12-01 2010-06-03 Estech, Llc Waste treatment autoclave to provide for steam - assisted drying

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3126395A (en) * 1964-03-24 Chj czhs
US3560495A (en) * 1965-05-08 1971-02-02 Ernst Frankus 1-heterocyclic amino methyl or 1-heterocyclic hydrazino methyl-3-phthalimido or (3',6'-dithia-3',4',5',6'-tetrahydrophthalimido)-pyrrolidinediones-2,5 or piperidinediones-2,6
US4061763A (en) * 1975-05-09 1977-12-06 Merck & Co., Inc. Tricyclicdicarboximides
US4139533A (en) * 1976-08-19 1979-02-13 Bristol-Myers Company Bicyclo[2,2,1]heptane-2,3-diendo carboxylic acid imide esters of quinoline carboxylic acid
US4748182A (en) * 1986-03-05 1988-05-31 Merrell Dow Pharmaceuticals Inc. Aromatic 2-aminoalkyl-1,2-benzoisothiazol-3(2H)one-1,1-dioxide derivatives and their use as anti-hypertensive and anxiolytic agents
DE3640641A1 (de) * 1986-11-28 1988-07-14 Thomae Gmbh Dr K Neue heteroaromatische aminderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
IE69761B1 (en) 1996-10-02
PT96757A (pt) 1991-10-31
FI923492A7 (fi) 1992-08-03
DK37790D0 (da) 1990-02-13
DE69110124T2 (de) 1996-01-18
CA2074727A1 (en) 1991-08-14
ZA91886B (en) 1991-10-30
WO1991012252A1 (en) 1991-08-22
EP0515462A1 (en) 1992-12-02
NO923153D0 (no) 1992-08-12
US5126363A (en) 1992-06-30
FI923492A0 (fi) 1992-08-03
IE910260A1 (en) 1991-08-14
AU641482B2 (en) 1993-09-23
AU7326591A (en) 1991-09-03
IL97105A0 (en) 1992-03-29
PT96757B (pt) 1998-07-31
IL97105A (en) 1994-11-28
DK0515462T3 (da) 1995-10-02
JPH05503525A (ja) 1993-06-10
EP0515462B1 (en) 1995-05-31
NZ237066A (en) 1993-07-27
DE69110124D1 (de) 1995-07-06
DK37790A (da) 1991-08-14
FI923492L (fi) 1992-08-03
ATE123283T1 (de) 1995-06-15

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