NO923840L - Cardiobeskyttende tocoferolanaloger - Google Patents

Cardiobeskyttende tocoferolanaloger

Info

Publication number: NO923840L
Authority: NO; Norway
Prior art keywords: alkyl; tocoferol; analogs; cardio protective; phenyl
Prior art date: 1991-10-02

Application number

NO92923840A

Other languages

English (en)

Norwegian (no)

Other versions

NO923840D0 (no

Inventor

Johann Martin Grisar

Margaret Anne Petty

Frank Bolkenius

Original Assignee

Merrell Dow Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-10-02

Filing date

1992-10-01

Publication date

1993-04-05

1992-10-01 Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma

1992-10-01 Publication of NO923840D0 publication Critical patent/NO923840D0/no

1993-04-05 Publication of NO923840L publication Critical patent/NO923840L/no

Links

230000003293 cardioprotective effect Effects 0.000 title 1
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
125000006545 (C1-C9) alkyl group Chemical group 0.000 abstract 1
125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
125000003710 aryl alkyl group Chemical group 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
- C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Molecular Biology (AREA)
Cardiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)
Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Inspection Of Paper Currency And Valuable Securities (AREA)
Noodles (AREA)
Credit Cards Or The Like (AREA)
Polyesters Or Polycarbonates (AREA)
Cosmetics (AREA)
Fire-Detection Mechanisms (AREA)
Photoreceptors In Electrophotography (AREA)
Absorbent Articles And Supports Therefor (AREA)
Medicines Containing Plant Substances (AREA)
Saccharide Compounds (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

NO92923840A 1991-10-02 1992-10-01 Cardiobeskyttende tocoferolanaloger NO923840L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP91402630A EP0535283A1 (en)	1991-10-02	1991-10-02	Cardioprotective tocopherol analogs

Publications (2)

Publication Number	Publication Date
NO923840D0 NO923840D0 (no)	1992-10-01
NO923840L true NO923840L (no)	1993-04-05

Family

ID=8208620

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO92923840A NO923840L (no)	1991-10-02	1992-10-01	Cardiobeskyttende tocoferolanaloger

Country Status (17)

Country	Link
EP (2)	EP0535283A1 (mo)
JP (1)	JP3230699B2 (mo)
KR (1)	KR100253108B1 (mo)
AT (1)	ATE163421T1 (mo)
AU (1)	AU652077B2 (mo)
CA (1)	CA2079289C (mo)
DE (1)	DE69224501T2 (mo)
DK (1)	DK0536036T3 (mo)
ES (1)	ES2115656T3 (mo)
FI (1)	FI105552B (mo)
GR (1)	GR3026242T3 (mo)
HU (1)	HU215123B (mo)
IL (1)	IL103305A0 (mo)
NO (1)	NO923840L (mo)
NZ (1)	NZ244549A (mo)
TW (1)	TW224970B (mo)
ZA (1)	ZA927429B (mo)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5721233A (en) *	1992-04-06	1998-02-24	Merrell Pharmaceuticals Inc.	Derivatives of 2,3-dihydro benzofuranols
US5510373A (en) *	1992-04-06	1996-04-23	Merrell Pharmaceuticals Inc.	Cardioprotective agents
US5545660A (en) *	1992-04-07	1996-08-13	Merrell Pharmaceuticals Inc.	Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans
CN1318434C (zh) *	1997-11-25	2007-05-30	安迪珀蒂恩生物工艺学有限公司	线粒体靶向的抗氧剂
AUPR549901A0 (en)	2001-06-06	2001-07-12	Vital Health Sciences Pty Ltd	Topical formulation containing tocopheryl phosphates
MXPA04000654A (es)	2001-07-27	2004-03-19	Vital Health Sciences Pty Ltd	Terapia dermica usando derivados de fosfato de agente de transferencia de electrones.
EP1374882B1 (de) *	2002-06-19	2008-10-01	Cognis IP Management GmbH	Verwendung von Wirkstoffgemischen zur Herstellung eines Medikamentes gegen rheumatische Arthritis
AU2002950713A0 (en)	2002-08-09	2002-09-12	Vital Health Sciences Pty Ltd	Carrier
KR101003960B1 (ko)	2003-08-22	2010-12-30	안티포딘 파마슈티칼스, 인코포레이티드	미토콘드리아 표적화 산화방지제로서 사용되는 미토퀴논 유도체를 포함하는 약제학적 조성물
US7888334B2 (en)	2003-08-22	2011-02-15	Antipodean Pharmaceuticals, Inc.	Mitoquinone derivatives used as mitochondrially targeted antioxidants
WO2005033092A1 (en)	2003-09-19	2005-04-14	Galileo Pharmaceuticals, Inc.	Chroman derivatives
RU2477136C2 (ru)	2004-03-03	2013-03-10	Вайтал Хэлф Сайнсис Пти Лтд	Алкалоидные составы
US9168216B2 (en)	2005-06-17	2015-10-27	Vital Health Sciences Pty. Ltd.	Carrier comprising one or more di and/or mono-(electron transfer agent) phosphate derivatives or complexes thereof
US7813042B2 (en)	2005-09-12	2010-10-12	Sharp Kabushiki Kaisha	Multiple-view directional display
WO2008029891A1 (en)	2006-09-07	2008-03-13	Sharp Kabushiki Kaisha	Image display device, electronic device, and parallax barrier element
WO2011094814A1 (en)	2010-02-05	2011-08-11	Phosphagenics Limited	Carrier comprising non-neutralised tocopheryl phosphate
CA2794734C (en)	2010-03-30	2017-12-12	Phosphagenics Limited	Transdermal delivery patch
WO2012122586A1 (en)	2011-03-15	2012-09-20	Phosphagenics Limited	New composition
US10973761B2 (en)	2015-12-09	2021-04-13	Phosphagenics Limited	Pharmaceutical formulation
JP7198754B2 (ja)	2016-12-21	2023-01-04	アベーチョバイオテクノロジーリミテッド	方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS62205091A (ja) *	1986-03-04	1987-09-09	Senjiyu Seiyaku Kk	新規なリン酸ジエステルならびにその塩、その製造法およびそれを含有する製剤
CA2002649C (en) *	1988-11-14	2000-06-06	Margaret Petty	Cardioprotective tocopherol analogs
US5500444A (en)	1989-11-14	1996-03-19	Hoechst Marion Roussel, Inc.	Cardioprotective tocopherol analogs
US5135945A (en)	1991-06-05	1992-08-04	Merrell Dow Pharmaceuticals Inc.	Cholesterol-lowering tocopherol analogs

1991
- 1991-10-02 EP EP91402630A patent/EP0535283A1/en not_active Withdrawn
1992
- 1992-09-28 AU AU25383/92A patent/AU652077B2/en not_active Ceased
- 1992-09-28 ZA ZA927429A patent/ZA927429B/xx unknown
- 1992-09-28 CA CA002079289A patent/CA2079289C/en not_active Expired - Fee Related
- 1992-09-29 EP EP92402656A patent/EP0536036B1/en not_active Expired - Lifetime
- 1992-09-29 ES ES92402656T patent/ES2115656T3/es not_active Expired - Lifetime
- 1992-09-29 DK DK92402656.0T patent/DK0536036T3/da active
- 1992-09-29 NZ NZ24454992A patent/NZ244549A/en unknown
- 1992-09-29 TW TW081107688A patent/TW224970B/zh active
- 1992-09-29 AT AT92402656T patent/ATE163421T1/de not_active IP Right Cessation
- 1992-09-29 DE DE69224501T patent/DE69224501T2/de not_active Expired - Fee Related
- 1992-09-30 IL IL103305A patent/IL103305A0/xx unknown
- 1992-10-01 FI FI924424A patent/FI105552B/fi active
- 1992-10-01 NO NO92923840A patent/NO923840L/no unknown
- 1992-10-01 HU HU9203134A patent/HU215123B/hu not_active IP Right Cessation
- 1992-10-01 KR KR1019920018013A patent/KR100253108B1/ko not_active Expired - Fee Related
- 1992-10-02 JP JP28704592A patent/JP3230699B2/ja not_active Expired - Fee Related
1998
- 1998-02-26 GR GR980400390T patent/GR3026242T3/el unknown

Also Published As

Publication number	Publication date
CA2079289C (en)	2003-02-18
FI924424A0 (fi)	1992-10-01
JPH05310763A (ja)	1993-11-22
FI105552B (fi)	2000-09-15
HU9203134D0 (en)	1992-12-28
TW224970B (mo)	1994-06-11
HUT62592A (en)	1993-05-28
EP0536036B1 (en)	1998-02-25
EP0536036A1 (en)	1993-04-07
EP0535283A1 (en)	1993-04-07
DE69224501T2 (de)	1998-06-25
IL103305A0 (en)	1993-02-21
ES2115656T3 (es)	1998-07-01
JP3230699B2 (ja)	2001-11-19
DK0536036T3 (da)	1998-03-16
ATE163421T1 (de)	1998-03-15
CA2079289A1 (en)	1993-04-03
AU2538392A (en)	1993-04-08
NZ244549A (en)	1994-07-26
KR100253108B1 (ko)	2000-05-01
FI924424L (fi)	1993-04-03
NO923840D0 (no)	1992-10-01
GR3026242T3 (en)	1998-05-29
ZA927429B (en)	1993-04-07
AU652077B2 (en)	1994-08-11
HU215123B (hu)	1998-09-28
DE69224501D1 (de)	1998-04-02

Publication	Publication Date	Title
ES2071230T3 (es)	1995-06-16	Composicion para el tratamiento del cabello.
NO950297L (no)	1995-07-28	Prolinamidderivater
ES2156853T3 (es)	2001-08-01	Derivados de quinolina.
RU94016161A (ru)	1995-09-10	Способ получения производных iii или 10-дезацетилбаккатина iii и их применение
ATE127450T1 (de)	1995-09-15	Prostaglandine.
CA2079289A1 (en)	1993-04-03	Cardioprotective tocopherol analogs
EP0632031A4 (mo)	1995-02-08
AU511183B2 (en)	1980-07-31	N-(4-(substituted benzyloxy)phenyl)-n'-methyl-n'- methoxyurea
GB1456514A (en)	1976-11-24	Substituted dialkyl 2-oxopropylphosphonates
MY113518A (en)	2002-03-30	Benzothiazolone derivatives
SG94086G (en)	1989-01-27	Sulphur-containing indole derivatives
BG99593A (en)	1995-12-29	Application of dtmethylbenzofurans as 5-ht3 antagonists
FR2424253A1 (fr)	1979-11-23	Nouveaux derives de peptides analogues des enkephalines, leur procede de preparation et leur application therapeutique
DK0556024T3 (da)	1995-09-18	Nye amidinonaphthyl-furancarboxylat-derivater og syreadditionssalte deraf
IL48453A (en)	1980-06-30	Substituted 6-oxa-1-azatricyclo-(6.2.2.0 )dodecan-5-ones and 1,4-ethano-5-oxo octa (or decahydro)quinoline,their preparation and pharmaceutical compositions containing them
ES2177539T3 (es)	2002-12-16	Benzoxacinas 4-oxo- y 4h-imidazo(5,1-c)(1,4) utilez como agentes de union de receptores de benzodiacepina.
US4152523A (en)	1979-05-01	11-Deoxy-17-phenyl-13,14-dihydro-PGE1 compounds
ES468353A1 (es)	1979-10-01	Procedimiento para preparar acidos 15-deoxi-16-hidroxi-sus- tituido-prostanoicos opticamente activosÿ
SU579844A3 (ru)	1977-11-05	Гербицидный состав
GB1451039A (en)	1976-09-29	Aryl carboxylic acids as hypolipemic agents
NO912875L (no)	1992-01-27	Fremgangsmaate for fremstilling av nye substituerte piperidiner.
ES2088112T3 (es)	1996-08-01	Nuevos esteres del acido 3-(3,3,3-trifluoro-2-cloropropenil)-2,2-dimetil-ciclopropanocarboxilico, su procedimiento de preparacion y su aplicacion como plaguicidas.
DE58900265D1 (de)	1991-10-17	Klebstoff.
US3974191A (en)	1976-08-10	16-Fluoro prostaglandin F1 analogs
GB1408854A (en)	1975-10-08	Alkyloxalyl amino substited s-triazines