ATE127450T1 - Prostaglandine. - Google Patents

Prostaglandine.

Info

Publication number: ATE127450T1
Authority: AT; Austria
Prior art keywords: phenyl; prostaglandins; trinor; dihydro; stands
Prior art date: 1991-06-24

Application number

AT92915265T

Other languages

English (en)

Inventor

Jozsef Ivanics

Tibor Szab

Istvan Hermecz

Gyula Dalmadi

Jozsefne Ivanics

Gaborne Kovacs

Resul Bahram

Original Assignee

Pharmacia Ab

Chinoin Gyogyszer Es Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-06-24

Filing date

1992-06-19

Publication date

1995-09-15

1992-06-19 Application filed by Pharmacia Ab, Chinoin Gyogyszer Es Vegyeszet filed Critical Pharmacia Ab

1995-09-15 Application granted granted Critical

1995-09-15 Publication of ATE127450T1 publication Critical patent/ATE127450T1/de

Links

229940094443 oxytocics prostaglandins Drugs 0.000 title 1
150000003180 prostaglandins Chemical class 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
125000004122 cyclic group Chemical group 0.000 abstract 1
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
229920006395 saturated elastomer Polymers 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Ophthalmology & Optometry (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Furan Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Emergency Lowering Means (AREA)
Catalysts (AREA)
Physical Or Chemical Processes And Apparatus (AREA)

AT92915265T 1991-06-24 1992-06-19 Prostaglandine. ATE127450T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU912092A HU212570B (en)	1991-06-24	1991-06-24	Process for producing 13,14-dihydro-15(r)-17-phenyl-18,19,20-trinor-pgf2alfa-isopropylester

Publications (1)

Publication Number	Publication Date
ATE127450T1 true ATE127450T1 (de)	1995-09-15

Family

ID=10957725

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT92915265T ATE127450T1 (de)	1991-06-24	1992-06-19	Prostaglandine.

Country Status (23)

Country	Link
US (1)	US5466833A (de)
EP (1)	EP0544899B1 (de)
JP (1)	JP2635213B2 (de)
KR (1)	KR0163022B1 (de)
CN (1)	CN1035764C (de)
AT (1)	ATE127450T1 (de)
AU (1)	AU656994B2 (de)
BG (1)	BG61261B1 (de)
CZ (1)	CZ287168B6 (de)
DE (1)	DE69204627T2 (de)
DK (1)	DK0544899T3 (de)
ES (1)	ES2078055T3 (de)
FI (1)	FI104895B (de)
GR (1)	GR3017874T3 (de)
HU (1)	HU212570B (de)
IE (1)	IE71645B1 (de)
IL (1)	IL102280A (de)
PL (1)	PL170728B1 (de)
RO (1)	RO117323B1 (de)
RU (1)	RU2099325C1 (de)
TW (1)	TW310321B (de)
UA (1)	UA39864C2 (de)
WO (1)	WO1993000329A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5510383A (en) †	1993-08-03	1996-04-23	Alcon Laboratories, Inc.	Use of cloprostenol, fluprostenol and their salts and esters to treat glaucoma and ocular hypertension
US6294563B1 (en)	1994-10-27	2001-09-25	Allergan Sales, Inc.	Combinations of prostaglandins and brimonidine or derivatives thereof
US6225348B1 (en)	1998-08-20	2001-05-01	Alfred W. Paulsen	Method of treating macular degeneration with a prostaglandin derivative
IL134241A (en) *	2000-01-27	2006-06-11	Finetech Pharmaceutical Ltd	Process for the preparation of latanoprost
IL143477A (en)	2001-05-31	2009-07-20	Finetech Pharmaceutical Ltd	Process for the preparation of 17-phenyl-18,19,20-trinor-pgf2?? and its derivatives
GB0112699D0 (en) *	2001-05-24	2001-07-18	Resolution Chemicals Ltd	Process for the preparation of prostglandins and analogues thereof
US20110065129A1 (en) *	2001-07-27	2011-03-17	Lowe Derek B	Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation
US20050119262A1 (en) *	2003-08-21	2005-06-02	Pharmacia Corporation	Method for preventing or treating an optic neuropathy with a cox-2 inhibitor and an intraocular pressure reducing agent
ITRM20050231A1 (it) *	2005-05-13	2006-11-14	Technopharma Sa	Procedimento per la sintesi di derivati delle prostaglandine f.
US7511168B2 (en)	2006-01-18	2009-03-31	Shih-Yi Wei	Processes and intermediates for the preparations of prostaglandins
US8546114B2 (en)	2006-01-18	2013-10-01	Chirogate International Inc.	Processes for the preparation of optically active cyclopentenones and cyclopentenones prepared therefrom
JP2008037782A (ja) *	2006-08-04	2008-02-21	Daiichi Fine Chemical Co Ltd	プロスタグランジン誘導体の製造方法
US7642370B2 (en)	2006-08-07	2010-01-05	Daiichi Fine Chemical Co., Ltd.	Method for preparing prostaglandin derivative
IT1392492B1 (it)	2008-12-24	2012-03-09	Ind Chimica Srl	Processo per la purificazione del latanoprost, analogo sintetico della prostaglandina pgf2alfa.
MX2012007661A (es) *	2010-01-11	2012-08-01	Inotek Pharmaceuticals Corp	Combinacion, kit y metodo para reducir la presion intraocular.
US8476247B2 (en)	2010-03-26	2013-07-02	Inotek Pharmaceuticals Corporation	Method of reducing intraocular pressure in humans
EP2495235B1 (de)	2011-03-04	2015-08-05	Newchem S.p.A.	Herstellungsverfahren zur Synthese von Prostaglandinen und Zwischenprodukte davon
KR102277188B1 (ko)	2011-06-02	2021-07-15	키노인 제트알티.	프로스타글란딘 아미드의 신규한 제조 방법
HU231203B1 (hu)	2011-12-21	2021-10-28	CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt.	Új eljárás travoprost előállítására
CA2861009A1 (en)	2012-01-26	2013-08-01	Inotek Pharmaceuticals Corporation	Anhydrous polymorphs of [(2r,3s,4r,5r)-5-(6-(cyclopentylamino)-9h-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)} methyl nitrate and processes of preparation thereof
HU230744B1 (hu) *	2012-11-30	2018-01-29	CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt.	Új eljárás travoprost előállítására
AU2014239222A1 (en)	2013-03-15	2015-10-01	Inotek Pharmaceuticals Corporation	Ophthalmic formulations
HU231214B1 (hu)	2014-03-13	2021-11-29	CHINOIN Gyógyszer és Vegyészeti Termékek Gyára Zrt.	Új eljárás nagytisztaságú prosztaglandinok előállítására

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE786251A (fr) *	1971-07-14	1973-01-15	Ici Ltd	Nouveaux derives du cyclopentane
US3971826A (en) *	1972-07-13	1976-07-27	Pfizer Inc.	15-Substituted-ω-pentanorprostaglandins
ES2317964T5 (es) *	1988-09-06	2015-02-20	Pfizer Health Ab	Derivado de prostaglandina-F2alfa para el tratamiento de glaucoma o hipertensión ocular

1991
- 1991-06-24 HU HU912092A patent/HU212570B/hu unknown
1992
- 1992-06-19 PL PL92298127A patent/PL170728B1/pl unknown
- 1992-06-19 KR KR1019930700530A patent/KR0163022B1/ko not_active Expired - Lifetime
- 1992-06-19 UA UA94010047A patent/UA39864C2/uk unknown
- 1992-06-19 EP EP92915265A patent/EP0544899B1/de not_active Expired - Lifetime
- 1992-06-19 DK DK92915265.0T patent/DK0544899T3/da active
- 1992-06-19 JP JP5501414A patent/JP2635213B2/ja not_active Expired - Lifetime
- 1992-06-19 DE DE69204627T patent/DE69204627T2/de not_active Expired - Lifetime
- 1992-06-19 RO RO93-00230A patent/RO117323B1/ro unknown
- 1992-06-19 AT AT92915265T patent/ATE127450T1/de active
- 1992-06-19 AU AU22629/92A patent/AU656994B2/en not_active Expired
- 1992-06-19 RU RU9393004874A patent/RU2099325C1/ru active
- 1992-06-19 WO PCT/HU1992/000025 patent/WO1993000329A1/en not_active Ceased
- 1992-06-19 ES ES92915265T patent/ES2078055T3/es not_active Expired - Lifetime
- 1992-06-22 IL IL102280A patent/IL102280A/en not_active IP Right Cessation
- 1992-06-24 CN CN92108844A patent/CN1035764C/zh not_active Expired - Lifetime
- 1992-07-01 IE IE922026A patent/IE71645B1/en not_active IP Right Cessation
- 1992-09-23 TW TW081107537A patent/TW310321B/zh not_active IP Right Cessation
1993
- 1993-02-22 FI FI930773A patent/FI104895B/fi not_active IP Right Cessation
- 1993-02-23 BG BG97471A patent/BG61261B1/bg unknown
- 1993-02-24 CZ CZ1993271A patent/CZ287168B6/cs not_active IP Right Cessation
1994
- 1994-10-06 US US08/319,327 patent/US5466833A/en not_active Expired - Lifetime
1995
- 1995-10-25 GR GR950402979T patent/GR3017874T3/el unknown

Also Published As

Publication number	Publication date
ES2078055T3 (es)	1995-12-01
IE71645B1 (en)	1997-02-26
HU912092D0 (en)	1991-12-30
DK0544899T3 (da)	1995-10-23
AU656994B2 (en)	1995-02-23
CZ287168B6 (en)	2000-10-11
HUT62561A (en)	1993-05-28
RU2099325C1 (ru)	1997-12-20
BG97471A (bg)	1994-03-24
CZ27193A3 (en)	1993-10-13
CN1072408A (zh)	1993-05-26
FI930773A7 (fi)	1993-02-22
IE922026A1 (en)	1992-12-30
BG61261B1 (en)	1997-04-30
GR3017874T3 (en)	1996-01-31
HU212570B (en)	1996-08-29
IL102280A (en)	1998-02-08
WO1993000329A1 (en)	1993-01-07
KR0163022B1 (ko)	1999-01-15
DE69204627D1 (de)	1995-10-12
TW310321B (de)	1997-07-11
PL298127A1 (en)	1994-01-24
UA39864C2 (uk)	2001-07-16
JPH06500804A (ja)	1994-01-27
JP2635213B2 (ja)	1997-07-30
FI930773A0 (fi)	1993-02-22
FI104895B (fi)	2000-04-28
AU2262992A (en)	1993-01-25
EP0544899A1 (de)	1993-06-09
US5466833A (en)	1995-11-14
RO117323B1 (ro)	2002-01-30
PL170728B1 (pl)	1997-01-31
EP0544899B1 (de)	1995-09-06
CN1035764C (zh)	1997-09-03
DE69204627T2 (de)	1996-05-02

Legal Events

Date	Code	Title	Description
1996-05-15	UEP	Publication of translation of european patent specification

Publication	Publication Date	Title
DE69204627D1 (de)	1995-10-12	Prostaglandine.
YU164791A (sh)	1994-04-05	Nezasićene hidroksialkilhinolin kiseline
FR2383927A1 (fr)	1978-10-13	Pyridylmethyl-esters substitues d'acides cyclopropanecarboxyliques utilisables comme insecticides
ATE204875T1 (de)	2001-09-15	Fungizide tetrahydrofurane
DK144690D0 (da)	1990-06-13	Fremgangsmaade til fremstilling af 7-substituerede hept-6-en- og -heptansyrer og derivater og mellemprodukter deraf
ATE78465T1 (de)	1992-08-15	Kathartica.
EP0533828A4 (en)	1993-08-11	Pgf 1-alcohols and their use as ocular hypotensives
DE69033069D1 (de)	1999-05-27	Prostaglandinanaloge
SE8600413D0 (sv)	1986-01-30	Nytt lekemedel och sett att framstella detsamma
YU48089B (sh)	1997-01-08	Novi derivati tetrazola i postupak za njihovo pripremanje
GR930100259A (el)	1994-02-28	Μικροβιακή μέ?οδος παρασκευής μεβινολίνης.
ATE46501T1 (de)	1989-10-15	Abkoemmlinge der guanidinomethylbenzoesaeure.
ES449430A1 (es)	1977-07-16	Procedimiento para preparar n-metilcarbamatos de 2, 3-dihi- drobenzofuranil-(7) n-sulfenilados.
ES459186A1 (es)	1978-11-01	Un procedimiento para la preparacion de un compuesto de aci-do poliprenilcarboxilico.
JPS523046A (en)	1977-01-11	Prepration of 4-homotwistane-3-carboxylic acid esters
FR2398717A1 (fr)	1979-02-23	Procede de preparation d'un fluorure d'acide fluore possedant un groupe ester
NO943861L (no)	1994-10-13	Trisyklisk forbindelse til bruk som tachykinin-antagonist
ES8707193A1 (es)	1987-07-16	Un metodo para producir derivados de bromodicloroimidazol
DE69313521D1 (de)	1997-10-09	PGE1-Analoge
SE8204791D0 (sv)	1982-08-20	Process for preparing alkoxy-vincaminic acid esters and alkoxy-apovincaminic acid esters
FR2361363A1 (fr)	1978-03-10	Derives de prostaglandines oxygenees en position 10
ES2069881T3 (es)	1995-05-16	Derivado de 15-desoxiprostaglandina.
ES2034070T3 (es)	1993-04-01	Ester del acido tionofosfonico.
FR2395250A1 (fr)	1979-01-19	Derives des acides amino- du guanidino-phenylpropioniques
ES2178357T3 (es)	2002-12-16	Nuevos compuestos del benzo-ciclobutano, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.