NO930890L - Fremgangsmaate for fremstilling av karbohydrater - Google Patents

Fremgangsmaate for fremstilling av karbohydrater

Info

Publication number
NO930890L
NO930890L NO93930890A NO930890A NO930890L NO 930890 L NO930890 L NO 930890L NO 93930890 A NO93930890 A NO 93930890A NO 930890 A NO930890 A NO 930890A NO 930890 L NO930890 L NO 930890L
Authority
NO
Norway
Prior art keywords
oligosaccharides
procedure
peptides
carbohydrates
preparation
Prior art date
Application number
NO93930890A
Other languages
English (en)
Other versions
NO930890D0 (no
Inventor
Sau-Chi Betty Yan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of NO930890D0 publication Critical patent/NO930890D0/no
Publication of NO930890L publication Critical patent/NO930890L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

En fremgangsmåte for fremstilling av peptlder Inneholdende ollgosakkarlder med sekvensen GalNAce(l-4) (Fuca(1-3) )GlcNAc ved Inkuberlng av humane nyre 293 celler som uttrykker et peptld som kan bil glykosylert under betingelser egnede for ekspresjon av peptidet og deretter isolering av peptidet fra cellen eller cellekultursupernatanten er beskrevet. Fremgangsmåten for videre Isolering av de nye oligosakkaridene fra peptidet produsert i 293 celler er også beskrevet. Peptidene og/eller oligosakkaridene som blir produsert kan bli anvendt som høye affinitetsligander til visse celleadhesjonsreseptorer. Peptidene og/eller oligosak- karidene kan bli anvendt for å forhindre eller redusere celleadhesjon og betennelse.
NO93930890A 1992-03-12 1993-03-11 Fremgangsmaate for fremstilling av karbohydrater NO930890L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US84986892A 1992-03-12 1992-03-12

Publications (2)

Publication Number Publication Date
NO930890D0 NO930890D0 (no) 1993-03-11
NO930890L true NO930890L (no) 1993-09-13

Family

ID=25306715

Family Applications (1)

Application Number Title Priority Date Filing Date
NO93930890A NO930890L (no) 1992-03-12 1993-03-11 Fremgangsmaate for fremstilling av karbohydrater

Country Status (23)

Country Link
EP (1) EP0565241B1 (no)
JP (1) JP3171506B2 (no)
KR (1) KR930019696A (no)
CN (1) CN1079967A (no)
AT (1) ATE137241T1 (no)
AU (1) AU661762B2 (no)
BR (1) BR9301136A (no)
CA (1) CA2091521A1 (no)
CY (1) CY1947A (no)
CZ (1) CZ39093A3 (no)
DE (1) DE69302317T2 (no)
DK (1) DK0565241T3 (no)
ES (1) ES2088227T3 (no)
FI (1) FI931086A7 (no)
GR (1) GR3020406T3 (no)
HK (1) HK132396A (no)
HU (1) HUT69613A (no)
IL (1) IL105018A0 (no)
MX (1) MX9301344A (no)
NO (1) NO930890L (no)
NZ (1) NZ247105A (no)
YU (1) YU16993A (no)
ZA (1) ZA931723B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE456664T1 (de) * 2001-04-02 2010-02-15 Glycomedics Inc Verfahren zur herstellung von oligosaccharidketten
FI20011664L (fi) 2001-08-17 2003-02-18 Carbion Oy Syöpäpesifiset oligoskkaridisekvenssit ja niiden käyttö
US7943763B2 (en) * 2002-07-05 2011-05-17 Otsuka Chemical Holdings Co., Ltd. Process for preparing glycopeptides having asparagine-linked oligosaccharides, and the glycopeptides
TWI247749B (en) * 2002-12-26 2006-01-21 Yasuhiro Kajihara 3 branch type saccharide chain asparagine derivative, saccharide chain asparagine there of, saccharide chain there of, and method for producing same
JP3884725B2 (ja) 2003-06-03 2007-02-21 三菱電機株式会社 導波管装置

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5009889A (en) * 1987-12-31 1991-04-23 Oklahoma Medical Research Foundation Treatment of dysfunctional vascular endothelium using activated protein C

Also Published As

Publication number Publication date
FI931086A0 (fi) 1993-03-11
HUT69613A (en) 1995-09-28
JP3171506B2 (ja) 2001-05-28
GR3020406T3 (en) 1996-09-30
EP0565241A1 (en) 1993-10-13
BR9301136A (pt) 1993-09-28
ES2088227T3 (es) 1996-08-01
DE69302317D1 (de) 1996-05-30
MX9301344A (es) 1993-09-01
DE69302317T2 (de) 1996-09-19
NZ247105A (en) 1994-11-25
CN1079967A (zh) 1993-12-29
YU16993A (sh) 1996-02-19
FI931086L (fi) 1993-09-13
CZ39093A3 (en) 1994-03-16
ZA931723B (en) 1994-09-10
IL105018A0 (en) 1993-07-08
AU661762B2 (en) 1995-08-03
ATE137241T1 (de) 1996-05-15
FI931086A7 (fi) 1993-09-13
JPH0625302A (ja) 1994-02-01
CA2091521A1 (en) 1993-09-13
NO930890D0 (no) 1993-03-11
AU3519993A (en) 1993-09-16
HU9300687D0 (en) 1993-05-28
EP0565241B1 (en) 1996-04-24
CY1947A (en) 1993-03-12
HK132396A (en) 1996-07-26
KR930019696A (ko) 1993-10-18
DK0565241T3 (da) 1996-05-28

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