NO931905L - 8-en-19, 11beta-broede steroider, deres fremstilling og farmasoeytiske preparater inneholdende disse - Google Patents

8-en-19, 11beta-broede steroider, deres fremstilling og farmasoeytiske preparater inneholdende disse

Info

Publication number
NO931905L
NO931905L NO93931905A NO931905A NO931905L NO 931905 L NO931905 L NO 931905L NO 93931905 A NO93931905 A NO 93931905A NO 931905 A NO931905 A NO 931905A NO 931905 L NO931905 L NO 931905L
Authority
NO
Norway
Prior art keywords
preparation
steroids
11beta
wide
pharmaceutical preparations
Prior art date
Application number
NO93931905A
Other languages
English (en)
Other versions
NO931905D0 (no
Inventor
Eckhardt Ottow
Guenter Neef
Walter Elger
Martin Schneider
Karl-Heinrich Fritzemeier
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of NO931905D0 publication Critical patent/NO931905D0/no
Publication of NO931905L publication Critical patent/NO931905L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Beskrevet er 8-en-19,llp-broede steroider av generell formel I som har et nytt strukturtrykk i form av en dobbeltbinding mellom 8-stilling og 9-stilling. Også beskrevet er en metode for fremstilling av disse. Substituentene R1, R4-Y, R<'-Y' og Z er som definert i beskrivelsen. De nye for- bindelser har i særdeleshet en sterk antiprogestational aktivitet og er egnet for fremstilling av farmasøytiske formuleringer.
NO93931905A 1990-11-27 1993-05-26 8-en-19, 11beta-broede steroider, deres fremstilling og farmasoeytiske preparater inneholdende disse NO931905L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4038128A DE4038128A1 (de) 1990-11-27 1990-11-27 8-en-19, 11(beta)-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate
PCT/EP1991/002239 WO1992009618A1 (de) 1990-11-27 1991-11-27 8-EN-19, 11β-ÜBERBRÜCKTE STEROIDE, DEREN HERSTELLUNG UND DIESE ENTHALTENDE PHARMAZEUTISCHE PRÄPARATE

Publications (2)

Publication Number Publication Date
NO931905D0 NO931905D0 (no) 1993-05-26
NO931905L true NO931905L (no) 1993-05-26

Family

ID=6419242

Family Applications (2)

Application Number Title Priority Date Filing Date
NO93931905A NO931905L (no) 1990-11-27 1993-05-26 8-en-19, 11beta-broede steroider, deres fremstilling og farmasoeytiske preparater inneholdende disse
NO972028A NO972028D0 (no) 1990-11-27 1997-04-30 Kjemiske forbindelser og antikonsepsjonsmidler inneholdende disse

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO972028A NO972028D0 (no) 1990-11-27 1997-04-30 Kjemiske forbindelser og antikonsepsjonsmidler inneholdende disse

Country Status (14)

Country Link
US (1) US5478956A (no)
EP (1) EP0559690B1 (no)
JP (1) JP3202229B2 (no)
AT (1) ATE154031T1 (no)
AU (1) AU661831B2 (no)
CA (1) CA2097079A1 (no)
DE (2) DE4038128A1 (no)
DK (1) DK0559690T3 (no)
ES (1) ES2106091T3 (no)
FI (1) FI932388A0 (no)
GR (1) GR3024611T3 (no)
HU (1) HUT64363A (no)
NO (2) NO931905L (no)
WO (1) WO1992009618A1 (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4235220A1 (de) * 1992-10-13 1994-06-16 Schering Ag Gestagen wirksame 19,11ß-überbrückte 4-Estrene
US6090798A (en) * 1997-12-19 2000-07-18 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with glucocorticoid antagonists
US6372712B1 (en) 1998-05-22 2002-04-16 The Board Of Trustees Of The Leland Stanford Jr. University Synthetic bifunctional molecules containing a drug moiety and presenter protein ligand
AU1161601A (en) * 1999-11-05 2001-05-14 University College London Activators of soluble guanylate cyclase
US7191438B2 (en) * 2001-02-23 2007-03-13 Lenovo (Singapore) Pte, Ltd. Computer functional architecture and a locked down environment in a client-server architecture
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
MY150763A (en) 2006-10-24 2014-02-28 Repros Therapeutics Inc Compositions and methods for suppressing endometrial proliferation
TWI539953B (zh) 2008-04-28 2016-07-01 瑞波若斯治療學公司 用於治療乳癌之組成物和方法
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
MX2012010327A (es) 2010-03-22 2012-11-16 Repros Therapeutics Inc Composiciones y metodos para la administracion no toxica de antiprogestinas.
US20110233118A1 (en) * 2010-03-29 2011-09-29 Nelson Steven D Sports bottle device with filter isolated from filtered fluid

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3127423A (en) * 1962-09-21 1964-03-31 Olin Mathieson Phenyl derivatives of methylsterols and process for production thereof
DE3708942A1 (de) * 1987-03-18 1988-09-29 Schering Ag 19,11ss-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate
DE3717169A1 (de) * 1987-05-19 1988-12-01 Schering Ag 19,11ss-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate
DE3832303A1 (de) * 1988-09-20 1990-04-12 Schering Ag 11ss-phenyl-14ssh-steroide
DE3917274A1 (de) * 1989-05-24 1990-11-29 Schering Ag 9(alpha)-hydroxy-19, 11(beta)-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate
US5041434A (en) * 1991-08-17 1991-08-20 Virginia Lubkin Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application

Also Published As

Publication number Publication date
AU661831B2 (en) 1995-08-10
HUT64363A (en) 1993-12-28
FI932388L (fi) 1993-05-26
NO931905D0 (no) 1993-05-26
NO972028D0 (no) 1997-04-30
DK0559690T3 (da) 1997-12-29
NO972028L (no) 1993-05-26
FI932388A7 (fi) 1993-05-26
US5478956A (en) 1995-12-26
GR3024611T3 (en) 1997-12-31
JPH06502631A (ja) 1994-03-24
ATE154031T1 (de) 1997-06-15
DE4038128A1 (de) 1992-06-04
ES2106091T3 (es) 1997-11-01
DE59108744D1 (de) 1997-07-10
EP0559690B1 (de) 1997-06-04
FI932388A0 (fi) 1993-05-26
HU9301542D0 (en) 1993-09-28
EP0559690A1 (de) 1993-09-15
WO1992009618A1 (de) 1992-06-11
AU8946091A (en) 1992-06-25
JP3202229B2 (ja) 2001-08-27
CA2097079A1 (en) 1992-05-28

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