ES2106091T3 - Esteroides 8-eno-19,11beta-puenteados, su preparacion y preparados farmaceuticos que los contienen. - Google Patents

Esteroides 8-eno-19,11beta-puenteados, su preparacion y preparados farmaceuticos que los contienen.

Info

Publication number
ES2106091T3
ES2106091T3 ES91920328T ES91920328T ES2106091T3 ES 2106091 T3 ES2106091 T3 ES 2106091T3 ES 91920328 T ES91920328 T ES 91920328T ES 91920328 T ES91920328 T ES 91920328T ES 2106091 T3 ES2106091 T3 ES 2106091T3
Authority
ES
Spain
Prior art keywords
pharmaceutical preparations
steroids
11beta
eno
bridged
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91920328T
Other languages
English (en)
Inventor
Eckhardt Ottow
Gunter Neef
Walter Elger
Martin Schneider
Karl-Heinrich Fritzemeier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Application granted granted Critical
Publication of ES2106091T3 publication Critical patent/ES2106091T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/36—Antigestagens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)

Abstract

SE DESCRIBEN ESTEROIDES PUENTEADOS EN 8 TA), DE FORMULA GENERAL (I), QUE PRESENTAN COMO NUEVA CARACTERISTICA ESTRUCTURAL, EL DOBLE ENLACE 8,9, ASI COMO UN PROCEDIMIENTO PARA SU OBTENCION. LOS SUSTITUYENTES R1, R4-Y, R4''-Y'', X Y Z TIENEN LOS SIGNIFICADOS DADOS EN LA DESCRIPCION. LOS NUEVOS COMPUESTOS OFRECEN ESPECIALMENTE UNA FUERTE ACCION ANTIGESTAGENA, Y SON ADECUADOS PARA LA OBTENCION DE PREPARADOS FARMACEUTICOS.
ES91920328T 1990-11-27 1991-11-27 Esteroides 8-eno-19,11beta-puenteados, su preparacion y preparados farmaceuticos que los contienen. Expired - Lifetime ES2106091T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4038128A DE4038128A1 (de) 1990-11-27 1990-11-27 8-en-19, 11(beta)-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate

Publications (1)

Publication Number Publication Date
ES2106091T3 true ES2106091T3 (es) 1997-11-01

Family

ID=6419242

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91920328T Expired - Lifetime ES2106091T3 (es) 1990-11-27 1991-11-27 Esteroides 8-eno-19,11beta-puenteados, su preparacion y preparados farmaceuticos que los contienen.

Country Status (14)

Country Link
US (1) US5478956A (es)
EP (1) EP0559690B1 (es)
JP (1) JP3202229B2 (es)
AT (1) ATE154031T1 (es)
AU (1) AU661831B2 (es)
CA (1) CA2097079A1 (es)
DE (2) DE4038128A1 (es)
DK (1) DK0559690T3 (es)
ES (1) ES2106091T3 (es)
FI (1) FI932388A7 (es)
GR (1) GR3024611T3 (es)
HU (1) HUT64363A (es)
NO (2) NO931905D0 (es)
WO (1) WO1992009618A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4235220A1 (de) * 1992-10-13 1994-06-16 Schering Ag Gestagen wirksame 19,11ß-überbrückte 4-Estrene
US6090798A (en) * 1997-12-19 2000-07-18 Alcon Laboratories, Inc. Treatment of GLC1A glaucoma with glucocorticoid antagonists
AU4093799A (en) 1998-05-22 1999-12-13 Board Of Trustees Of The Leland Stanford Junior University Bifunctional molecules and therapies based thereon
EP1237849A1 (en) * 1999-11-05 2002-09-11 University College London Activators of soluble guanylate cyclase
US7191438B2 (en) * 2001-02-23 2007-03-13 Lenovo (Singapore) Pte, Ltd. Computer functional architecture and a locked down environment in a client-server architecture
CA2789262C (en) 2005-04-28 2016-10-04 Proteus Digital Health, Inc. Pharma-informatics system
EP1945240B1 (en) 2005-09-16 2016-12-28 Raptor Pharmaceutical Inc Compositions comprising receptor-associated protein (rap) variants specific for cr-containing proteins and uses thereof
AU2007327707B2 (en) 2006-10-24 2012-07-12 Allergan pharmaceuticals International Ltd. Compositions and methods for suppressing endometrial proliferation
TWI539953B (zh) 2008-04-28 2016-07-01 瑞波若斯治療學公司 用於治療乳癌之組成物和方法
TR201908314T4 (tr) 2009-02-20 2019-06-21 2 Bbb Medicines B V Glutatyon bazlı ilaç dağıtım sistemi.
KR101909711B1 (ko) 2009-05-06 2018-12-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
CN107260745A (zh) 2010-03-22 2017-10-20 利普生物药剂公司 用于抗孕酮的非毒性递送的组合物和方法
US20110233118A1 (en) * 2010-03-29 2011-09-29 Nelson Steven D Sports bottle device with filter isolated from filtered fluid

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3127423A (en) * 1962-09-21 1964-03-31 Olin Mathieson Phenyl derivatives of methylsterols and process for production thereof
DE3708942A1 (de) * 1987-03-18 1988-09-29 Schering Ag 19,11ss-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate
DE3717169A1 (de) * 1987-05-19 1988-12-01 Schering Ag 19,11ss-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate
DE3832303A1 (de) * 1988-09-20 1990-04-12 Schering Ag 11ss-phenyl-14ssh-steroide
DE3917274A1 (de) * 1989-05-24 1990-11-29 Schering Ag 9(alpha)-hydroxy-19, 11(beta)-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate
US5041434A (en) * 1991-08-17 1991-08-20 Virginia Lubkin Drugs for topical application of sex steroids in the treatment of dry eye syndrome, and methods of preparation and application

Also Published As

Publication number Publication date
FI932388L (fi) 1993-05-26
HU9301542D0 (en) 1993-09-28
EP0559690B1 (de) 1997-06-04
FI932388A0 (fi) 1993-05-26
AU8946091A (en) 1992-06-25
WO1992009618A1 (de) 1992-06-11
DE59108744D1 (de) 1997-07-10
CA2097079A1 (en) 1992-05-28
EP0559690A1 (de) 1993-09-15
AU661831B2 (en) 1995-08-10
US5478956A (en) 1995-12-26
NO931905L (no) 1993-05-26
DE4038128A1 (de) 1992-06-04
JP3202229B2 (ja) 2001-08-27
GR3024611T3 (en) 1997-12-31
DK0559690T3 (da) 1997-12-29
NO972028L (no) 1993-05-26
FI932388A7 (fi) 1993-05-26
NO972028D0 (no) 1997-04-30
NO931905D0 (no) 1993-05-26
ATE154031T1 (de) 1997-06-15
HUT64363A (en) 1993-12-28
JPH06502631A (ja) 1994-03-24

Similar Documents

Publication Publication Date Title
ES2150989T3 (es) Nuevos derivados de quinoxalinadiona, su preparacion y empleo en medicamentos.
ES2058185T3 (es) Derivados de camptotecina y procedimiento para su preparacion.
ES2106091T3 (es) Esteroides 8-eno-19,11beta-puenteados, su preparacion y preparados farmaceuticos que los contienen.
CL2004001128A1 (es) Compuestos derivados de halogenopirimidinas aril eter; composicion pesticida; procedimiento de preparacion; compuestos intermediarios; y uso del compuesto como agente pesticida.
CO4130326A1 (es) Nuevos derivados de 2-ciano-1,3-diona, composiciones que los contienen, procedimientos para su preparacion y su uso como herbicidas
ES2167377T3 (es) Derivados de piridina farmacologicamente activos y procedimientos para la preparacion de los mismos.
ES2059408T3 (es) Un proceso para la preparacion de un compuesto.
NO952151L (no) Injiserbare, taxanderivat-baserte preparater
ES2148476T3 (es) Derivados de azabicicloalcano n-substituidos como neurolepticos asf.
ES2084944T3 (es) Amidas terapeuticas.
ES2112377T3 (es) Procedimiento para la preparacion de derivados del taxano y productos intermedios.
ES2038337T3 (es) 2,2-difluorociclopropiletano, procedimientos para su preparacion y su utilizacion como agentes plaguicidas.
MX9204354A (es) Compuestos heterociclicos de 5 miembros, procedimiento para prepararlos y composiciones farmaceuticas que los contienen.
ATE226815T1 (de) Herstellung von arzneimitteln
ES2186783T3 (es) Derivados de la dolastatina, su preparacion y uso.
FI940696A0 (fi) Uudet pyratsiinijohdannaiset, niiden valmistus ja käyttö
ES2107035T3 (es) Derivados de 3-azabiciclo(3.2.0)heptano n-substituidos como neurolepticos etc..
ES2166928T3 (es) Derivados de ciclopentanbutanol como odorantes.
ES2160602T3 (es) Derivados de quinolona y acridinona para el tratamiento de la incontinencia urinaria.
ES2118955T3 (es) Derivados de dolastatina.
ES2042556T3 (es) N,n'-diacilhidrazinas n-sustituidas, n'-sustituidas insecticidas.
MX9303123A (es) Ciclopentano-y-penteno-beta-aminoacidos, procedimiento para su preparacion y medicamentos que los contienen.
ES2043863T3 (es) Procedimiento para preparar derivados de la 1,2,5,6-tetrahidropiridina.
MY104979A (en) [ 5(6)(ih-azole-1-ylmethyl) benzimidazole] carbamates.
AR001813A1 (es) Derivados de cromona procedimiento para prepararlos y las composiciones farmacéutica que los contienen

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 559690

Country of ref document: ES