NO932003L - Nye tiosemikarbazoner - Google Patents

Nye tiosemikarbazoner

Info

Publication number
NO932003L
NO932003L NO932003A NO932003A NO932003L NO 932003 L NO932003 L NO 932003L NO 932003 A NO932003 A NO 932003A NO 932003 A NO932003 A NO 932003A NO 932003 L NO932003 L NO 932003L
Authority
NO
Norway
Prior art keywords
alkyl
aryl
alkoxy
alkene
hydrogen
Prior art date
Application number
NO932003A
Other languages
English (en)
Other versions
NO932003D0 (no
Inventor
Martin Missbach
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO932003D0 publication Critical patent/NO932003D0/no
Publication of NO932003L publication Critical patent/NO932003L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/54—Nitrogen and either oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Det er beskrevet nye tiosemlkarbazoner med formel I hvori R1 betyr laverealkyl, laverealk-2-en-l-yl eller også laverealk-2-in-l-yl, R2 °8 RS betyr uavhengig av hverandre hydrogen eller laverealkyl eller står sammen for laverealkyliden, R4 betyr hydrogen, laverealkyl, laverealkoksy, aryl eller aryllaverealkyl eller gruppen -C(-0)-R6, hvori R6 står for laverealkyl, aryl, heteroaryl, aryloksy, aryllaverealkoksy eller laverealk-2-en-l-yloksy, R5 betyr aryl, aryllaverealkyl, umettet eller mettet heterocyklyllaverealkyl, laverealkoksykarbonyllavere- alkyl eller gruppen -C(-0)-R7, hvori R7 står for laverealkyl, aryl, aryllaverealkyl, aryllaverealkenyl, heteroaryl, aryloksy, aryllaverealkoksy eller lavere- alk-2-en-l-yloksy eller R5 betyr også laverealkyl, laverealk-2-en-l-yl eller laverealk-2-ln-l-yl, når R4 er forskjellig fra hydrogen, og deres salter, fremgangsmåter for fremstilling av de angitte forbin- delsene, farmasøytiske preparater inneholdende disse og deres anvendelse som legemiddel-vlrkestoffer.
NO932003A 1992-06-03 1993-06-02 Nye tiosemikarbazoner NO932003L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH177892 1992-06-03
CH177992 1992-06-03
CH311492 1992-10-06

Publications (2)

Publication Number Publication Date
NO932003D0 NO932003D0 (no) 1993-06-02
NO932003L true NO932003L (no) 1993-12-06

Family

ID=27173241

Family Applications (1)

Application Number Title Priority Date Filing Date
NO932003A NO932003L (no) 1992-06-03 1993-06-02 Nye tiosemikarbazoner

Country Status (11)

Country Link
US (1) US5344842A (no)
EP (1) EP0573392A1 (no)
JP (1) JPH06172333A (no)
KR (1) KR940005600A (no)
AU (1) AU665073B2 (no)
CA (1) CA2097485A1 (no)
FI (1) FI932511A7 (no)
HU (1) HUT67605A (no)
IL (1) IL105887A (no)
NO (1) NO932003L (no)
NZ (1) NZ247749A (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU664084B2 (en) * 1992-06-03 1995-11-02 Ciba-Geigy Ag Novel thiosemicarbazonic acid esters
HUT71608A (en) * 1993-11-25 1996-01-29 Ciba Geigy Ag Novel substituted thiosemicarbazone derivatives, process for producing them and pharmaceutical compositions containing them
US6747061B2 (en) 2000-03-21 2004-06-08 Atherogenics, Inc. N-substituted dithiocarbamates for the treatment of biological disorders
KR20030030636A (ko) * 2001-10-12 2003-04-18 주식회사 싸이제닉 버섯 자실체의 발효를 이용하여 고활성 항암 단백다당체를제조하는 방법
CN1738797A (zh) 2002-11-19 2006-02-22 阿基里昂药品公司 取代的芳基硫脲和相关的化合物,病毒复制的抑制剂
KR100468649B1 (ko) * 2003-01-29 2005-01-27 학교법인 영광학원 항보체 활성을 갖는 운지버섯 자실체 유래의 다당체 및 그분리방법
TW200600492A (en) * 2004-05-18 2006-01-01 Achillion Pharmaceuticals Inc Substituted aryl acylthioureas and related compounds; inhibitors of viral replication
CN102453028B (zh) * 2010-10-22 2014-07-30 沈阳药科大学 抗真菌剂—2-[（2，3-二氢-4H-苯并[b]噻喃-4-亚基）亚肼基]-4-氧代四氢噻（噁）唑-5-乙酸衍生物

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3699116A (en) * 1965-10-29 1972-10-17 Ciba Geigy Corp 2,2'-azines of 2,4-thiazolidinediones
CH511877A (de) * 1969-07-17 1971-08-31 Ciba Geigy Ag Verfahren zur Herstellung eines neuen Thiosemicarbazons
US3674780A (en) * 1970-01-19 1972-07-04 American Cyanamid Co Novel 2,5-disubstituted thiazole carboxaldehyde and derivatives of the same
GB1325061A (en) * 1970-07-03 1973-08-01 Ciba Geigy Ag Process for the production of azines
AR204619A1 (es) * 1973-02-13 1976-02-20 Ciba Geigy Ag Procedimiento para la elaboracion de un nuevo derivado de 2,2-azina-2,4-tiazolidindiona
EP0085275B1 (de) * 1982-01-22 1986-02-19 Ciba-Geigy Ag Substituierte Thiazolidinylester von Mineralsäuren
AU658175B2 (en) * 1991-04-12 1995-04-06 Novartis Ag Use of 2-iminothiazolidin-4-one derivatives as novel pharmaceutical active ingredients
AU664084B2 (en) * 1992-06-03 1995-11-02 Ciba-Geigy Ag Novel thiosemicarbazonic acid esters

Also Published As

Publication number Publication date
FI932511A0 (fi) 1993-06-02
AU665073B2 (en) 1995-12-14
IL105887A0 (en) 1993-10-20
HUT67605A (en) 1995-04-28
CA2097485A1 (en) 1993-12-04
KR940005600A (ko) 1994-03-21
JPH06172333A (ja) 1994-06-21
HU9301616D0 (en) 1993-09-28
EP0573392A1 (de) 1993-12-08
IL105887A (en) 1997-01-10
NO932003D0 (no) 1993-06-02
NZ247749A (en) 1995-08-28
US5344842A (en) 1994-09-06
FI932511A7 (fi) 1993-12-04
AU3856793A (en) 1993-12-09

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