NO933147L - Imidazoakridiner og deres antieoplastiske anvendelse - Google Patents

Imidazoakridiner og deres antieoplastiske anvendelse

Info

Publication number: NO933147L
Authority: NO; Norway
Prior art keywords: alkyl; imidazoacridines; antieoplastic; applications; hydrogen
Prior art date: 1991-03-05

Application number

NO93933147A

Other languages

English (en)

Other versions

NO300175B1 (no

NO933147D0 (no

Inventor

Wieslaw Marek Cholody

Jerzy Kazimierz Konopa

Original Assignee

British Tech Group

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-03-05

Filing date

1993-09-03

Publication date

1993-09-03

1993-09-03 Application filed by British Tech Group filed Critical British Tech Group

1993-09-03 Publication of NO933147D0 publication Critical patent/NO933147D0/no

1993-09-03 Publication of NO933147L publication Critical patent/NO933147L/no

1997-04-21 Publication of NO300175B1 publication Critical patent/NO300175B1/no

Links

230000000118 anti-neoplastic effect Effects 0.000 title abstract 2
125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 1
UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
150000001204 N-oxides Chemical class 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
125000004432 carbon atom Chemical group C* 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
239000012458 free base Substances 0.000 abstract 1
150000002431 hydrogen Chemical group 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
208000032839 leukemia Diseases 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
238000011321 prophylaxis Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000011282 treatment Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Hematology (AREA)
Oncology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

NO933147A 1991-03-05 1993-09-03 Imidazoakridiner og deres antineoplastiske sammensetninger NO300175B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB919104548A GB9104548D0 (en)	1991-03-05	1991-03-05	Antineoplastic modified imidazoacridines
PCT/GB1992/000360 WO1992015583A1 (en)	1991-03-05	1992-02-28	Imidazoacridines and their antineoplastic use

Publications (3)

Publication Number	Publication Date
NO933147D0 NO933147D0 (no)	1993-09-03
NO933147L true NO933147L (no)	1993-09-03
NO300175B1 NO300175B1 (no)	1997-04-21

Family

ID=10690967

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO933147A NO300175B1 (no)	1991-03-05	1993-09-03	Imidazoakridiner og deres antineoplastiske sammensetninger

Country Status (17)

Country	Link
US (1)	US5231100A (no)
EP (2)	EP0502668A1 (no)
JP (1)	JP3176062B2 (no)
AT (1)	ATE153664T1 (no)
AU (1)	AU654700B2 (no)
CA (1)	CA2051356C (no)
DE (1)	DE69220048T2 (no)
DK (1)	DK0579614T3 (no)
ES (1)	ES2103931T3 (no)
GB (2)	GB9104548D0 (no)
GR (1)	GR3024485T3 (no)
IE (1)	IE66260B1 (no)
IL (1)	IL101139A (no)
NO (1)	NO300175B1 (no)
PL (1)	PL167640B1 (no)
WO (1)	WO1992015583A1 (no)
ZA (1)	ZA921615B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0604181A1 (en) *	1992-12-21	1994-06-29	Eli Lilly And Company	Antitumor compositions and method of treatment
US5508289A (en) *	1994-03-14	1996-04-16	The United States America As Represented By The Department Of Health And Human Services	Bis-acridone chemotherapeutic derivatives
WO1997016191A1 (en) *	1995-11-02	1997-05-09	Warner-Lambert Company	Inhibition of amyloidosis by 9-acridinones
DE69709857T2 (de) *	1996-04-12	2002-08-29	The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Rockville	Acridonderivate als antineoplastische-und antiretrovirale mittel
GB2317888A (en) *	1996-10-07	1998-04-08	Marek Tadeusz Konieczny	Acridone derivatives and preparation of 8-hydroxy-imidazoacridinone derivatives
IT1293525B1 (it) *	1997-08-01	1999-03-01	Uni Degli Studi Camerino	Bis-acridincarbossiammidi aventi attivita' antitumorale
JP2003525940A (ja) *	2000-03-07	2003-09-02	アメリカ合衆国	抗−腫瘍活性を有する、１，８−ナフタルイミドイミダゾ〔４，５，１−ｄｅ〕アクリドン類
JP2008528616A (ja) *	2005-01-28	2008-07-31	ザンサスファーマシューティカルズ，インコーポレイテッド	炎症性疾患および脱髄性疾患を処置するための化合物
WO2007092436A2 (en) *	2006-02-08	2007-08-16	Xanthus Pharmaceuticals, Inc.	Compounds for treating inflammatory disorders, demyelinating disorders and cancers
WO2007143096A2 (en) *	2006-06-02	2007-12-13	Xanthus Pharmaceuticals, Inc.	Compounds for treating cancers
WO2008016660A2 (en) *	2006-08-02	2008-02-07	Xanthus Pharmaceuticals, Inc.	Imidazoacridine compounds for treating leukemias
US20100016300A1 (en) *	2006-08-02	2010-01-21	Ajami Alfred M	Imidazoacridine Compounds for Treating FLT3-Mediated Disorders
WO2008016700A2 (en) *	2006-08-02	2008-02-07	Xanthus Pharmaceuticals, Inc.	N-oxide compounds for therapeutics uses
US20080118576A1 (en) *	2006-08-28	2008-05-22	Dan Theodorescu	Prediction of an agent's or agents' activity across different cells and tissue types
US8470844B2 (en) *	2008-09-11	2013-06-25	Technion Research & Development Foundation Limited	Imidazoacridinone derivative compounds and methods for their use
EP3070078B1 (en) *	2015-03-20	2017-10-04	Politechnika Gdanska	Asymmetric bis-acridines with antitumor activity and use thereof
IL255290B2 (en) *	2015-04-27	2024-01-01	Medical Res Infrastructure & Health Services Fund Tel Aviv Medical Ct	Substances that bind to EGF1 and their use in the treatment of inflammatory diseases and tumors

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1037377A (en) *	1964-09-02	1966-07-27	Mitsubishi Chem Ind	Naphthoylene-arylimidazole disperse dyestuffs
US4626540A (en) *	1983-11-08	1986-12-02	Warner-Lambert Company	Substituted 1-amino-4-nitro-acridinones and methods of treating bacterial infections and leukemia with them
JP2795460B2 (ja) *	1988-06-20	1998-09-10	協和醗酵工業株式会社	ピラゾロアクリドン誘導体

1991
- 1991-03-05 GB GB919104548A patent/GB9104548D0/en active Pending
- 1991-09-16 US US07/760,694 patent/US5231100A/en not_active Expired - Lifetime
- 1991-09-16 CA CA002051356A patent/CA2051356C/en not_active Expired - Fee Related
1992
- 1992-02-28 DE DE69220048T patent/DE69220048T2/de not_active Expired - Fee Related
- 1992-02-28 AT AT92905201T patent/ATE153664T1/de not_active IP Right Cessation
- 1992-02-28 JP JP50506892A patent/JP3176062B2/ja not_active Expired - Fee Related
- 1992-02-28 WO PCT/GB1992/000360 patent/WO1992015583A1/en not_active Ceased
- 1992-02-28 DK DK92905201.7T patent/DK0579614T3/da active
- 1992-02-28 GB GB9204315A patent/GB2253396B/en not_active Expired - Fee Related
- 1992-02-28 AU AU12743/92A patent/AU654700B2/en not_active Ceased
- 1992-02-28 EP EP92301732A patent/EP0502668A1/en active Pending
- 1992-02-28 ES ES92905201T patent/ES2103931T3/es not_active Expired - Lifetime
- 1992-02-28 PL PL92300593A patent/PL167640B1/pl not_active IP Right Cessation
- 1992-02-28 EP EP92905201A patent/EP0579614B1/en not_active Expired - Lifetime
- 1992-03-03 IE IE920677A patent/IE66260B1/en not_active IP Right Cessation
- 1992-03-04 ZA ZA921615A patent/ZA921615B/xx unknown
- 1992-03-04 IL IL10113992A patent/IL101139A/en not_active IP Right Cessation
1993
- 1993-09-03 NO NO933147A patent/NO300175B1/no unknown
1997
- 1997-08-19 GR GR970402124T patent/GR3024485T3/el unknown

Also Published As

Publication number	Publication date
DE69220048T2 (de)	1997-10-02
NO300175B1 (no)	1997-04-21
NO933147D0 (no)	1993-09-03
JPH06508102A (ja)	1994-09-14
AU1274392A (en)	1992-10-06
DK0579614T3 (da)	1997-12-15
ES2103931T3 (es)	1997-10-01
IL101139A0 (en)	1992-11-15
ZA921615B (en)	1992-11-25
CA2051356C (en)	2002-01-08
IE920677A1 (en)	1992-09-09
GR3024485T3 (en)	1997-11-28
US5231100A (en)	1993-07-27
EP0579614B1 (en)	1997-05-28
GB2253396B (en)	1994-08-10
ATE153664T1 (de)	1997-06-15
GB2253396A (en)	1992-09-09
GB9204315D0 (en)	1992-04-08
WO1992015583A1 (en)	1992-09-17
AU654700B2 (en)	1994-11-17
EP0579614A1 (en)	1994-01-26
IE66260B1 (en)	1995-12-27
PL167640B1 (pl)	1995-10-31
CA2051356A1 (en)	1992-09-06
EP0502668A1 (en)	1992-09-09
JP3176062B2 (ja)	2001-06-11
GB9104548D0 (en)	1991-04-17
DE69220048D1 (de)	1997-07-03
IL101139A (en)	1995-01-24

Publication	Publication Date	Title
NO933147D0 (no)	1993-09-03	Imidazoakridiner og deres antieoplastiske anvendelse
IL100788A (en)	1997-01-10	3-alkoxy or 3-cycloalkoxy 4-alkoxy derivatives of n-phenyl n-naphthyl or n-heterocyclyl substituted benzamides
HUP0102930A2 (hu)	2001-11-28	Vírusellenes makrociklusos vegyületek, ezeket tartalmazó gyógyászati készítmények és alkalmazásuk
DK0641767T3 (da)	1999-08-23	Cytotoksiske stilbenderivater og farmaceutisk præparat indeholdende disse derivater
AU1455788A (en)	1988-10-27	1-azabicyclic compounds
PH25859A (en)	1991-12-02	Composition for treatment of ischemic disorder
ES2103027T3 (es)	1997-08-16	Derivados de tienopiridina y composiciones farmaceuticas que los contienen.
DK0790987T3 (da)	2001-11-12	Aminotetrazol-derivater, der er anvendelige som nitrogenoxidsynthaseinhibitorer
ATE147386T1 (de)	1997-01-15	Kondensierte pyrimidinderivate, ihre herstellung und ihre verwendung als antitumormittel
NO940245L (no)	1994-07-29	Quinolin eller quinazolinderivater, deres fremstilling og anvendelse
SG66252A1 (en)	1999-07-20	6,9 bis(substituted-amino) benzo [g] isoquinoline-5, 10-di-ones
NO961077D0 (no)	1996-03-15	Substituerte benzoltienylpiperaziner, deres anvendelse som medikamenter og fremgangsmåter for fremstilling
IT1213301B (it)	1989-12-20	Composizioni per il trattamento del le sindromi da ischemia e riperfusione
HUT75647A (en)	1997-05-28	Imidazolidinone derivatives and pharmaceutical compositions containing them, which are suitable for treament of senile dementia
FI954213A0 (fi)	1995-09-08	Kasvainten vastaisia koostumuksia ja hoitomenetelmiä
ATE66475T1 (de)	1991-09-15	Aromatische thioaether.
NO174670C (no)	1994-06-15	Analogifremgangsmåte for fremstilling av terapeutisk aktive 1H-pyrido(4,3-b)indol-1-on-derivater
ATE132870T1 (de)	1996-01-15	Pyrrolo(2,1-b)thiazol-derivate