NO933153L - Fremgangsmåte for fremstilling av protease-inhibitorer - Google Patents

Fremgangsmåte for fremstilling av protease-inhibitorer

Info

Publication number: NO933153L
Authority: NO; Norway
Prior art keywords: preparation; protease inhibitors; yeast strains; transformed yeast; deulfatohirudin
Prior art date: 1992-09-04

Application number

NO933153A

Other languages

English (en)

Norwegian (no)

Other versions

NO933153D0 (no

Inventor

Jutta Heim

Peter Furst

Thomas Hottiger

Jochen Kuhla

Gabriele Pohlig

Original Assignee

Ciba Geigy Ag

Ucp Gen Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-09-04

Filing date

1993-09-03

Publication date

1994-03-07

1993-09-03 Application filed by Ciba Geigy Ag, Ucp Gen Pharma Ag filed Critical Ciba Geigy Ag

1993-09-03 Publication of NO933153D0 publication Critical patent/NO933153D0/no

1994-03-07 Publication of NO933153L publication Critical patent/NO933153L/no

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Biomedical Technology (AREA)
General Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Mycology (AREA)
Bioinformatics & Cheminformatics (AREA)
Biophysics (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Physics & Mathematics (AREA)
Plant Pathology (AREA)
Tropical Medicine & Parasitology (AREA)
Gastroenterology & Hepatology (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Enzymes And Modification Thereof (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Indole Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Ultra Sonic Daignosis Equipment (AREA)

NO933153A 1992-09-04 1993-09-03 Fremgangsmåte for fremstilling av protease-inhibitorer NO933153L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP92810681		1992-09-04

Publications (2)

Publication Number	Publication Date
NO933153D0 NO933153D0 (no)	1993-09-03
NO933153L true NO933153L (no)	1994-03-07

Family

ID=8211979

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO933153A NO933153L (no)	1992-09-04	1993-09-03	Fremgangsmåte for fremstilling av protease-inhibitorer

Country Status (20)

Country	Link
US (1)	US5726043A (de)
EP (2)	EP1031628A1 (de)
JP (2)	JP3949734B2 (de)
KR (1)	KR940007180A (de)
AT (1)	ATE196927T1 (de)
AU (1)	AU675071B2 (de)
CA (1)	CA2105425A1 (de)
DE (1)	DE69329540T2 (de)
DK (1)	DK0592358T3 (de)
ES (1)	ES2152943T3 (de)
FI (1)	FI933821A7 (de)
GR (1)	GR3035201T3 (de)
HU (1)	HU217094B (de)
IL (1)	IL106897A0 (de)
MX (1)	MX9305375A (de)
NO (1)	NO933153L (de)
NZ (1)	NZ248558A (de)
PT (1)	PT592358E (de)
SG (1)	SG49859A1 (de)
ZA (1)	ZA936507B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR19990010008A (ko) *	1997-07-14	1999-02-05	구광시	효모용 프로모터 및 이 프로모터를 포함하는 효모용발현 벡터
US6358705B1 (en)	1998-07-16	2002-03-19	Novo Nordisk A/S	Method of making proteins in transformed yeast cells
US7795205B2 (en) *	2004-04-12	2010-09-14	Canyon Pharmaceuticals, Inc.	Methods for effecting regression of tumor mass and size in a metastasized pancreatic tumor
US8940502B2 (en)	2006-07-14	2015-01-27	Novozymes, Inc.	Nucleic acid constructs and methods of making protein
CN102373216B (zh) *	2011-10-28	2013-06-05	元昊	一种含有医用水蛭素基因的重组真核汉逊酵母工程菌株的构建及重组水蛭素的生产工艺
EP3428282A1 (de) *	2017-07-11	2019-01-16	Alderys	Ectoine-herstellende hefe

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4940661A (en) *	1984-05-17	1990-07-10	Genentech, Inc.	Metallothionein transcription control sequences and use thereof
FR2593518B1 (fr) *	1985-05-02	1989-09-08	Transgene Sa	Vecteurs d'expression et de secretion de l'hirudine par les levures transformees
MY101203A (en) *	1985-12-12	1991-08-17	Ucp Gen Pharma Ag	Production of thrombin iinhibitors.
MC1834A1 (fr) *	1986-07-10	1988-06-03	Transgene Sa	Bloc fonctionnel d'adn et plasmide codant pour l'hirudine,levure transformee,procede de preparation de l'hirudine,hirudine obtenue et son utilisation
AU614959B2 (en) *	1987-05-07	1991-09-19	Commonwealth Scientific And Industrial Research Organisation	Expression system
PT88556B (pt) *	1987-09-28	1992-11-30	Smithkline Biolog	Processo de integracao genomica estavel e de expressao de uma sequencia de cadificacao estranha, em leveduras
GB8809860D0 (en) *	1988-04-26	1988-06-02	Ciba Geigy Ag	Process for production of polypeptides
AU614121B2 (en) *	1988-05-04	1991-08-22	Novartis Ag	Improvements in the production of polypeptides
FR2645175B1 (fr) *	1989-03-31	1994-02-18	Transgene Sa	Souche de saccharomyces cerevisiaeproductrice d'une proteine heterologue et procede de preparation de ladite proteine heterologue par fermentation de ladite souche

1993
- 1993-08-25 EP EP00107334A patent/EP1031628A1/de not_active Withdrawn
- 1993-08-25 SG SG9607683A patent/SG49859A1/en unknown
- 1993-08-25 EP EP93810608A patent/EP0592358B1/de not_active Expired - Lifetime
- 1993-08-25 DE DE69329540T patent/DE69329540T2/de not_active Expired - Lifetime
- 1993-08-25 DK DK93810608T patent/DK0592358T3/da active
- 1993-08-25 PT PT93810608T patent/PT592358E/pt unknown
- 1993-08-25 ES ES93810608T patent/ES2152943T3/es not_active Expired - Lifetime
- 1993-08-25 AT AT93810608T patent/ATE196927T1/de active
- 1993-08-30 AU AU44994/93A patent/AU675071B2/en not_active Ceased
- 1993-09-01 FI FI933821A patent/FI933821A7/fi unknown
- 1993-09-01 NZ NZ248558A patent/NZ248558A/en unknown
- 1993-09-02 CA CA002105425A patent/CA2105425A1/en not_active Abandoned
- 1993-09-02 MX MX9305375A patent/MX9305375A/es unknown
- 1993-09-03 JP JP22021593A patent/JP3949734B2/ja not_active Expired - Lifetime
- 1993-09-03 NO NO933153A patent/NO933153L/no not_active Application Discontinuation
- 1993-09-03 KR KR1019930017604A patent/KR940007180A/ko not_active Withdrawn
- 1993-09-03 IL IL106897A patent/IL106897A0/xx unknown
- 1993-09-03 HU HU9302503A patent/HU217094B/hu not_active IP Right Cessation
- 1993-09-03 ZA ZA936507A patent/ZA936507B/xx unknown
1996
- 1996-09-16 US US08/715,252 patent/US5726043A/en not_active Expired - Lifetime
2001
- 2001-01-10 GR GR20010400019T patent/GR3035201T3/el unknown
2003
- 2003-09-18 JP JP2003326835A patent/JP2004000288A/ja active Pending

Also Published As

Publication number	Publication date
EP0592358B1 (de)	2000-10-11
ATE196927T1 (de)	2000-10-15
HUT67307A (en)	1995-03-28
JPH06165691A (ja)	1994-06-14
KR940007180A (ko)	1994-04-26
JP3949734B2 (ja)	2007-07-25
DE69329540T2 (de)	2001-06-07
IL106897A0 (en)	1993-12-28
AU675071B2 (en)	1997-01-23
ZA936507B (en)	1994-03-23
GR3035201T3 (en)	2001-04-30
AU4499493A (en)	1994-03-10
PT592358E (pt)	2001-03-30
EP0592358A3 (en)	1994-09-28
EP1031628A1 (de)	2000-08-30
NO933153D0 (no)	1993-09-03
CA2105425A1 (en)	1994-03-05
HU217094B (hu)	1999-11-29
FI933821L (fi)	1994-03-05
HU9302503D0 (en)	1993-11-29
DE69329540D1 (de)	2000-11-16
ES2152943T3 (es)	2001-02-16
EP0592358A2 (de)	1994-04-13
SG49859A1 (en)	2002-03-19
FI933821A7 (fi)	1994-03-05
NZ248558A (en)	1995-04-27
DK0592358T3 (da)	2001-02-05
MX9305375A (es)	1994-03-31
JP2004000288A (ja)	2004-01-08
US5726043A (en)	1998-03-10
FI933821A0 (fi)	1993-09-01

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Legal Events

Date	Code	Title	Description
2002-09-30	FC2A	Withdrawal, rejection or dismissal of laid open patent application