NO933558L - Benzimidazoler, legemidler inneholdende disse forbindelser, og fremgangsmåte for deres fremstilling - Google Patents

Benzimidazoler, legemidler inneholdende disse forbindelser, og fremgangsmåte for deres fremstilling

Info

Publication number
NO933558L
NO933558L NO933558A NO933558A NO933558L NO 933558 L NO933558 L NO 933558L NO 933558 A NO933558 A NO 933558A NO 933558 A NO933558 A NO 933558A NO 933558 L NO933558 L NO 933558L
Authority
NO
Norway
Prior art keywords
compounds
benzimidazoles
drugs containing
preparation
rjj
Prior art date
Application number
NO933558A
Other languages
English (en)
Other versions
NO933558D0 (no
Inventor
Uwe Ries
Norbert Hauel
Jacques Van Meel
Wolfgang Wienen
Michael Entzeroth
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4233590A external-priority patent/DE4233590A1/de
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO933558D0 publication Critical patent/NO933558D0/no
Publication of NO933558L publication Critical patent/NO933558L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Det beskrives benzimidazoler med den generelle formel hvor Ra til Rjj er som definert i krav l, deres l-, 3-isomer- blandinger og deres salter, som oppviser verdifulle egen- skaper, legemidler som inneholder disse forbindelsene og deres anvendelse, samt fremgangsmåter for deres fremstilling. De nye forbindelsene utgjør spesielt angiotensin- antagonister.
NO933558A 1992-10-06 1993-10-05 Benzimidazoler, legemidler inneholdende disse forbindelser, og fremgangsmåte for deres fremstilling NO933558L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4233590A DE4233590A1 (de) 1992-10-06 1992-10-06 Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE4315349A DE4315349A1 (de) 1992-10-06 1993-05-08 Benzimidazole, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung

Publications (2)

Publication Number Publication Date
NO933558D0 NO933558D0 (no) 1993-10-05
NO933558L true NO933558L (no) 1994-04-07

Family

ID=25919224

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933558A NO933558L (no) 1992-10-06 1993-10-05 Benzimidazoler, legemidler inneholdende disse forbindelser, og fremgangsmåte for deres fremstilling

Country Status (16)

Country Link
US (1) US5521177A (no)
EP (1) EP0591891A3 (no)
JP (1) JPH06211807A (no)
KR (1) KR940009160A (no)
CN (1) CN1088202A (no)
CA (1) CA2107604A1 (no)
CZ (1) CZ207293A3 (no)
DE (1) DE4315349A1 (no)
FI (1) FI934343L (no)
HU (1) HUT65300A (no)
IL (1) IL107175A0 (no)
MX (1) MX9306178A (no)
NO (1) NO933558L (no)
NZ (1) NZ248850A (no)
PL (1) PL300585A1 (no)
SK (1) SK106693A3 (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5565454A (en) * 1995-05-31 1996-10-15 Ergo Science, Incorporated Method for preventing intervention-associated stenosis and other symptoms associated with stenosis of blood vessels following non-bypass, invasive interventions
EP0914158B2 (en) * 1996-04-05 2006-01-25 Takeda Chemical Industries, Ltd. Pharmaceutical combination containing a compound having angiotensin ii antagonistic activity and a compound which increases the insulin-sensitivity
HUP0003942A2 (hu) * 1997-05-07 2001-04-28 Novo Nordisk A/S Helyettesített 3,3-diamino-2-propén-nitrilek, előállításuk és alkalmazásuk
US5955548A (en) * 1997-05-07 1999-09-21 Novo Nordisk A/S Substituted 3, 3-diamino-2-propenenitriles, their preparation and use
US6916813B2 (en) * 2001-12-10 2005-07-12 Bristol-Myers Squibb Co. (1-phenyl-2-heteoaryl)ethyl-guanidine compounds as inhibitors of mitochondrial F1F0 ATP hydrolase
JPWO2005011736A1 (ja) * 2003-07-30 2006-09-14 株式会社 東北テクノアーチ アルツハイマー病の予防および／または治療剤
CA2647592C (en) * 2006-05-26 2014-01-28 Abbott Laboratories Inhibitors of polo-like kinases
WO2025207620A1 (en) * 2024-03-27 2025-10-02 Alterome Therapeutics, Inc. Akt1 modulators

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2121773T3 (es) * 1990-06-08 1998-12-16 Hoechst Marion Roussel Inc Derivados de bencimidazol, su procedimiento de preparacion, productos intermedios, su aplicacion como medicamentos y composiciones farmaceuticas que los contienen.
SI9210098B (sl) * 1991-02-06 2000-06-30 Dr. Karl Thomae Benzimidazoli, zdravila, ki te spojine vsebujejo, in postopek za njihovo pripravo

Also Published As

Publication number Publication date
SK106693A3 (en) 1994-08-10
NO933558D0 (no) 1993-10-05
NZ248850A (en) 1995-12-21
CZ207293A3 (en) 1994-04-13
EP0591891A2 (de) 1994-04-13
MX9306178A (es) 1995-01-31
JPH06211807A (ja) 1994-08-02
FI934343A7 (fi) 1994-04-07
IL107175A0 (en) 1994-01-25
KR940009160A (ko) 1994-05-20
FI934343A0 (fi) 1993-10-04
EP0591891A3 (en) 1994-07-20
HUT65300A (en) 1994-05-02
HU9302813D0 (en) 1993-12-28
FI934343L (fi) 1994-04-07
CN1088202A (zh) 1994-06-22
DE4315349A1 (de) 1994-11-10
CA2107604A1 (en) 1994-04-07
US5521177A (en) 1996-05-28
PL300585A1 (en) 1994-05-16

Similar Documents

Publication Publication Date Title
NO933248L (no) Cykliske urinstoffderivater, legemidler inneholdende disse forbindelser, og fremgangsmåte for deres fremstilling
NO941611D0 (no) Nye aminosyrederivater, fremgangsmåte for deres fremstilling og farmasöytiske preparater inneholdende disse forbindelser
NO20045369L (no) Nye, substituerte sulfamatanticonvulsivaderivater
NO971471L (no) Nye karboksamider med fungicid aktivitet
NO972881L (no) Piperazinderivater, legemidler som inneholder disse, anvendelse derav og fremgangsmåte for deres fremstilling
NO20055092L (no) Substituerte pyrimidioner
NO940261L (no) 5-leddete heterocykler, fremgangsmåte ved fremstilling derav og legemidler som inneholder disse forbindelser
NO972910L (no) Tetracykliske spiroforbindelser, fremgangsmåte for fremstilling og anvendelse derav som 5HT1D reseptor-antagonister
NO962543L (no) Cykliske amid-derivater som neurokinin A-antagonister
NO20064201L (no) Glukopyranosylsubstituerte benzolderivater, medikamenter inneholdende slike forbindelser, deres anvendelse og fremstilling
NO20051695L (no) Nye spirokondenserte kinazolinoner og deres anvendelse som fosfodiestereaseinbibitorer
EA200300248A1 (ru) Бициклопиразолы, активные в качестве ингибиторов киназы, способ их получения и включающие их фармацевтические композиции
NO964700L (no) Nye aminosyrederivater, fremgangsmåte til deres fremstilling og farmasöytiske blandinger som inneholder disse forbindelser
PL313075A1 (en) Heterocyclic compounds used as antagonistic substances in respect to neurokinin
DE69627035D1 (de) Derivate von aminosäuren, sie enthaltende pharmazeutische zusammensetzungen sowie deren herstellunsgverfahren
MXPA04000886A (es) Derivados de triazolil-imidazopiridina y triazolilpurinas empledos como ligandos del receptor de adenosina a2a y su uso como medicamentos.
DK0478446T3 (da) Heterocykliske alkylaminer, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
SE9702564D0 (sv) New compounds
DE69924292D1 (de) Pyrazol verbindungen und ihre verwendung
NO971625L (no) Nye peptider med immunomodulatoriske effekter
NO20054763L (no) Salter av clopidogrel og fremgangsmate for fremstilling derav
DE69229339D1 (de) Kristallines tiagabinehydrochlorid-monohydrat, seine herstellung und verwendung
NO931342L (no) Benzimidazoler, medisinske preparater inneholdende disse,og fremgangsmaate for deres fremstilling
DK1194415T3 (da) Nye piperazinylalkylthiopyrimidinderivater, farmaceutiske sammensætninger indeholdende disse samt en fremgangsmåde til deres fremstilling
NO933558L (no) Benzimidazoler, legemidler inneholdende disse forbindelser, og fremgangsmåte for deres fremstilling