NO933582L - Nye konjugater og analyser for simultan deteksjon av multiple ligander - Google Patents

Nye konjugater og analyser for simultan deteksjon av multiple ligander

Info

Publication number
NO933582L
NO933582L NO933582A NO933582A NO933582L NO 933582 L NO933582 L NO 933582L NO 933582 A NO933582 A NO 933582A NO 933582 A NO933582 A NO 933582A NO 933582 L NO933582 L NO 933582L
Authority
NO
Norway
Prior art keywords
binding
assays
simultaneous detection
target ligands
assay
Prior art date
Application number
NO933582A
Other languages
English (en)
Other versions
NO933582D0 (no
Inventor
Gunars Edwin Valkirs
Original Assignee
Biosite Diagnostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosite Diagnostics Inc filed Critical Biosite Diagnostics Inc
Publication of NO933582D0 publication Critical patent/NO933582D0/no
Publication of NO933582L publication Critical patent/NO933582L/no

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54306—Solid-phase reaction mechanisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)

Abstract

Nye konjugater og konkurrerende og ikke-konkurrerende analyser for samtidig påvisning av tilstedeværelsen eller mengden av minst to targetligander som kan konkurrere med et enkelt konjugat for binding til minst to forskjellige ligandreseptor- er. Oppfinnelsen lærer bindingsdomener koblet til et signal- utviklingselement til å danne et konjugat hvor hvert bindings- domene omfatter minst en ligandanalog eller ligandreseptor avhengig av analysedesign. Bindingsdomenene er konstruert slik at de kan fungere uavhengig i analyser for deres respek- tive targetligander. Hvert bindingsdomene kan binde sine respektive bindingspartnere i analysen uten å påvirke bind- ingsreaksjonene av andre bindingsdomener koblet til det samme signålutviklingselement, noe som gjør oppfinnelsen anvendbar i analysesystemer for samtidig påvisning av multiple target- ligander.
NO933582A 1991-04-12 1993-10-07 Nye konjugater og analyser for simultan deteksjon av multiple ligander NO933582L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68508491A 1991-04-12 1991-04-12
PCT/US1992/002839 WO1992018866A1 (en) 1991-04-10 1992-04-07 Novel conjugates and assays for simultaneous detection of multiple ligands

Publications (2)

Publication Number Publication Date
NO933582D0 NO933582D0 (no) 1993-10-07
NO933582L true NO933582L (no) 1993-12-10

Family

ID=24750715

Family Applications (1)

Application Number Title Priority Date Filing Date
NO933582A NO933582L (no) 1991-04-12 1993-10-07 Nye konjugater og analyser for simultan deteksjon av multiple ligander

Country Status (11)

Country Link
US (1) US5851776A (no)
EP (1) EP0579767B1 (no)
JP (1) JP3290988B2 (no)
AT (1) ATE195808T1 (no)
AU (1) AU1911592A (no)
CA (1) CA2107899A1 (no)
DE (1) DE69231382T2 (no)
ES (1) ES2150915T3 (no)
FI (1) FI934438A7 (no)
NO (1) NO933582L (no)
WO (1) WO1992018866A1 (no)

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EP0579767A4 (en) 1995-05-17
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NO933582D0 (no) 1993-10-07
ATE195808T1 (de) 2000-09-15
CA2107899A1 (en) 1992-10-11
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US5851776A (en) 1998-12-22
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JP3290988B2 (ja) 2002-06-10
DE69231382D1 (de) 2000-09-28
FI934438A7 (fi) 1993-11-04
JPH06507021A (ja) 1994-08-04
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AU1911592A (en) 1992-11-17
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