NO942757L - 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-okso-kinolin-derivater - Google Patents

4-aryl-3-(heteroarylureido)-1,2-dihydro-2-okso-kinolin-derivater

Info

Publication number
NO942757L
NO942757L NO942757A NO942757A NO942757L NO 942757 L NO942757 L NO 942757L NO 942757 A NO942757 A NO 942757A NO 942757 A NO942757 A NO 942757A NO 942757 L NO942757 L NO 942757L
Authority
NO
Norway
Prior art keywords
nitrogen
formula
compounds
independently
alkyl
Prior art date
Application number
NO942757A
Other languages
English (en)
Norwegian (no)
Other versions
NO942757D0 (no
Inventor
Ernest S Hamanaka
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO942757D0 publication Critical patent/NO942757D0/no
Publication of NO942757L publication Critical patent/NO942757L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO942757A 1992-01-23 1994-07-22 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-okso-kinolin-derivater NO942757L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82463992A 1992-01-23 1992-01-23
PCT/US1992/010886 WO1993015058A1 (fr) 1992-01-23 1992-12-21 Derives de 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline utilises comme agents antihypercholesterolemie et antiatherosclerose

Publications (2)

Publication Number Publication Date
NO942757D0 NO942757D0 (no) 1994-07-22
NO942757L true NO942757L (no) 1994-07-22

Family

ID=25241935

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942757A NO942757L (no) 1992-01-23 1994-07-22 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-okso-kinolin-derivater

Country Status (16)

Country Link
EP (1) EP0623112B1 (fr)
JP (1) JP2668163B2 (fr)
KR (1) KR950700284A (fr)
AT (1) ATE175196T1 (fr)
AU (1) AU3323393A (fr)
CA (1) CA2128093C (fr)
DE (1) DE69228069T2 (fr)
DK (1) DK0623112T3 (fr)
ES (1) ES2125325T3 (fr)
FI (2) FI930264A7 (fr)
HU (1) HUT63625A (fr)
IL (1) IL104420A0 (fr)
MX (1) MX9300361A (fr)
NO (1) NO942757L (fr)
WO (1) WO1993015058A1 (fr)
ZA (1) ZA93482B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133326A (en) * 1994-08-31 2000-10-17 Pfizer Inc Compositions and methods for decreasing sebum production
EP1086948A4 (fr) * 1998-02-25 2004-03-10 Sumitomo Pharma Derives de pyridone et leur procede de fabrication
US6452008B2 (en) 1998-02-25 2002-09-17 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for preparing the same
KR20020073574A (ko) 2000-02-02 2002-09-27 워너-램버트 캄파니 피지선 장애 치료용 콜레스테롤 에스테르 및 왁스에스테르 합성 이중 억제제
WO2006074147A2 (fr) 2005-01-03 2006-07-13 Myriad Genetics, Inc. Composes et utilisation therapeutique associee
US8309562B2 (en) 2003-07-03 2012-11-13 Myrexis, Inc. Compounds and therapeutical use thereof
WO2005003100A2 (fr) 2003-07-03 2005-01-13 Myriad Genetics, Inc. Composes et leur utilisation therapeutique
FR2874922A1 (fr) * 2004-07-30 2006-03-10 Palumed Sa Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
EP1771456A2 (fr) * 2004-07-30 2007-04-11 Palumed SA Molecules hybrides qa ou q est une aminoquinoleine et a est un residu antibiotique, leur synthese et leurs utilisations en tant qu'agent antibacterien
US8258145B2 (en) 2005-01-03 2012-09-04 Myrexis, Inc. Method of treating brain cancer
US11618751B1 (en) 2022-03-25 2023-04-04 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 derivatives
US11319319B1 (en) 2021-04-07 2022-05-03 Ventus Therapeutics U.S., Inc. Compounds for inhibiting NLRP3 and uses thereof
US12331048B2 (en) 2022-10-31 2025-06-17 Ventus Therapeutics U.S., Inc. Pyrido-[3,4-d]pyridazine amine derivatives useful as NLRP3 inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
WO1991004027A1 (fr) * 1989-09-15 1991-04-04 Pfizer Inc. Nouveaux derives de n-aryle de n-heteroarylamide et d'uree en tant qu'inhibiteurs d'acyl coenzyme a: cholesterol acyl transferase
TW205037B (fr) * 1989-10-06 1993-05-01 Takeda Pharm Industry Co Ltd
US5278186A (en) * 1990-02-10 1994-01-11 Takeda Chemical Industries, Ltd. Chromene derivatives, their production and use
CA2108014A1 (fr) * 1991-04-26 1992-10-27 Ernest S. Hamanaka Derives 4-aryl-3-(heteroarylureido)quinoline

Also Published As

Publication number Publication date
MX9300361A (es) 1994-06-30
JPH07503712A (ja) 1995-04-20
WO1993015058A1 (fr) 1993-08-05
DE69228069T2 (de) 1999-05-20
HU9300197D0 (en) 1993-04-28
CA2128093C (fr) 1998-02-03
DK0623112T3 (da) 1999-08-30
FI20010074A7 (fi) 2001-01-12
NO942757D0 (no) 1994-07-22
HUT63625A (en) 1993-09-28
DE69228069D1 (de) 1999-02-11
ATE175196T1 (de) 1999-01-15
FI930264A7 (fi) 1993-07-24
ZA93482B (en) 1994-07-22
JP2668163B2 (ja) 1997-10-27
IL104420A0 (en) 1993-05-13
ES2125325T3 (es) 1999-03-01
EP0623112A1 (fr) 1994-11-09
KR950700284A (ko) 1995-01-16
EP0623112B1 (fr) 1998-12-30
FI930264A0 (fi) 1993-01-22
AU3323393A (en) 1993-09-01
CA2128093A1 (fr) 1993-08-05

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