NO951126L - Transdermalt matrikssystem basert på en styren-isopren-styren-kopolymer for administrasjon av et östrogen og/eller et progestogen - Google Patents

Transdermalt matrikssystem basert på en styren-isopren-styren-kopolymer for administrasjon av et östrogen og/eller et progestogen

Info

Publication number: NO951126L
Authority: NO; Norway
Prior art keywords: weight; styrene; parts; group; isoprene
Prior art date: 1994-03-28

Application number

NO951126A

Other languages

English (en)

Norwegian (no)

Other versions

NO951126D0 (no

Inventor

Claude Mikler

Laurent Liorzou

Daniel Dhuique-Mayer

Original Assignee

Lhd Lab Hygiene Dietetique

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-03-28

Filing date

1995-03-24

Publication date

1995-09-29

1995-03-24 Application filed by Lhd Lab Hygiene Dietetique filed Critical Lhd Lab Hygiene Dietetique

1995-03-24 Publication of NO951126D0 publication Critical patent/NO951126D0/no

1995-09-29 Publication of NO951126L publication Critical patent/NO951126L/no

Links

239000011159 matrix material Substances 0.000 title abstract 5
229920001577 copolymer Polymers 0.000 title 1
239000000262 estrogen Substances 0.000 title 1
229940011871 estrogen Drugs 0.000 title 1
239000000583 progesterone congener Substances 0.000 title 1
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 abstract 2
229940088597 hormone Drugs 0.000 abstract 2
239000005556 hormone Substances 0.000 abstract 2
ALSTYHKOOCGGFT-KTKRTIGZSA-N (9Z)-octadecen-1-ol Chemical compound CCCCCCCC\C=C/CCCCCCCCO ALSTYHKOOCGGFT-KTKRTIGZSA-N 0.000 abstract 1
125000006732 (C1-C15) alkyl group Chemical group 0.000 abstract 1
125000000954 2-hydroxyethyl group Chemical group [H]C([*])([H])C([H])([H])O[H] 0.000 abstract 1
239000000853 adhesive Substances 0.000 abstract 1
239000004840 adhesive resin Substances 0.000 abstract 1
229920006223 adhesive resin Polymers 0.000 abstract 1
229960000541 cetyl alcohol Drugs 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
229960003338 crotamiton Drugs 0.000 abstract 1
125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
LLRANSBEYQZKFY-UHFFFAOYSA-N dodecanoic acid;propane-1,2-diol Chemical compound CC(O)CO.CCCCCCCCCCCC(O)=O LLRANSBEYQZKFY-UHFFFAOYSA-N 0.000 abstract 1
230000001076 estrogenic effect Effects 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
229940049964 oleate Drugs 0.000 abstract 1
229940055577 oleyl alcohol Drugs 0.000 abstract 1
XMLQWXUVTXCDDL-UHFFFAOYSA-N oleyl alcohol Natural products CCCCCCC=CCCCCCCCCCCO XMLQWXUVTXCDDL-UHFFFAOYSA-N 0.000 abstract 1
-1 peglicolS-oleate Chemical compound 0.000 abstract 1
239000004014 plasticizer Substances 0.000 abstract 1
229920000346 polystyrene-polyisoprene block-polystyrene Polymers 0.000 abstract 1
230000000757 progestagenic effect Effects 0.000 abstract 1
239000003381 stabilizer Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system

Landscapes

Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Life Sciences & Earth Sciences (AREA)
Dermatology (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Botany (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Adhesives Or Adhesive Processes (AREA)

NO951126A 1994-03-28 1995-03-24 Transdermalt matrikssystem basert på en styren-isopren-styren-kopolymer for administrasjon av et östrogen og/eller et progestogen NO951126L (no)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9403599A FR2717689B1 (fr)	1994-03-28	1994-03-28	Système matriciel transdermique d'administration d'un oestrogène et/ou un progestatif à base de copolymère styrène-isoprène-styrène.

Publications (2)

Publication Number	Publication Date
NO951126D0 NO951126D0 (no)	1995-03-24
NO951126L true NO951126L (no)	1995-09-29

Family

ID=9461479

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO951126A NO951126L (no)	1994-03-28	1995-03-24	Transdermalt matrikssystem basert på en styren-isopren-styren-kopolymer for administrasjon av et östrogen og/eller et progestogen

Country Status (23)

Country	Link
US (1)	US5580572A (cs)
EP (1)	EP0674901B1 (cs)
JP (1)	JPH07330609A (cs)
KR (1)	KR950031057A (cs)
CN (1)	CN1114903A (cs)
AT (1)	ATE173618T1 (cs)
AU (1)	AU691558B2 (cs)
CA (1)	CA2145584A1 (cs)
CZ (1)	CZ76795A3 (cs)
DE (1)	DE69506157T2 (cs)
DK (1)	DK0674901T3 (cs)
ES (1)	ES2128673T3 (cs)
FI (1)	FI951424A7 (cs)
FR (1)	FR2717689B1 (cs)
GR (1)	GR3029401T3 (cs)
HU (1)	HU219465B (cs)
LV (1)	LV10929B (cs)
NO (1)	NO951126L (cs)
NZ (1)	NZ270811A (cs)
PL (1)	PL178896B1 (cs)
RU (1)	RU2110282C1 (cs)
SK (1)	SK39095A3 (cs)
ZA (1)	ZA952469B (cs)

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JP3238389B2 (ja) *	1988-10-27	2001-12-10	シエーリングアクチエンゲゼルシヤフト	ゲストデン含有の経皮適用のための薬剤
US6148830A (en)	1994-04-19	2000-11-21	Applied Elastomerics, Inc.	Tear resistant, multiblock copolymer gels and articles
US7208184B2 (en)	2002-07-20	2007-04-24	Applied Elastomerics, Inc.	Gelatinous food elastomer compositions and articles for use as fishing bait
US7134236B2 (en) *	1994-04-19	2006-11-14	Applied Elastomerics, Inc.	Gelatinous elastomer compositions and articles for use as fishing bait
US7108873B2 (en)	1994-04-19	2006-09-19	Applied Elastomerics, Inc.	Gelatinous food elastomer compositions and articles
US7226484B2 (en)	1994-04-19	2007-06-05	Applied Elastomerics, Inc.	Tear resistant gels and articles for every uses
US7290367B2 (en)	1994-04-19	2007-11-06	Applied Elastomerics, Inc.	Tear resistant gel articles for various uses
US7234560B2 (en) *	1994-04-19	2007-06-26	Applied Elastomerics, Inc.	Inflatable restraint cushions and other uses
EP0787488A4 (en) *	1994-11-18	1998-06-03	Hisamitsu Pharmaceutical Co	TRANSDERMAL ABSORBABLE PLASTER
FR2739031B1 (fr) *	1995-09-27	1997-11-21	Lhd Lab Hygiene Dietetique	Systeme matriciel transdermique d'administration d'un oestrogene et/ou d'un progestatif a base de copolymere styrene-isoprene-styrene, procede de preparation et utilisation en therapeutique
JP3857348B2 (ja) *	1996-02-20	2006-12-13	ソニー株式会社	テープカートリッジ
DE19700913C2 (de) *	1997-01-14	2001-01-04	Lohmann Therapie Syst Lts	Transdermales therapeutisches System zur Abgabe von Hormonen
DE19918106A1 (de) *	1999-04-22	2000-10-26	Lohmann Therapie Syst Lts	Transdermales therapeutisches System mit neutralisierten Acrylathaftklebern
WO2001001990A1 (en) *	1999-07-01	2001-01-11	Hisamitsu Pharmaceutical Co., Inc.	Adhesive preparation for percutaneous absorption
JP4648518B2 (ja) *	2000-06-01	2011-03-09	帝國製薬株式会社	４−ビフェニル酢酸含有貼付剤
DE10236319A1 (de) *	2002-08-08	2004-02-19	Beiersdorf Ag	Hautfreundliche Wirkstoffpflaster auf der Basis von SBC mit mindestens einem pharmazeutischen Wirkstoff mit einem Gehalt von mindestens 34 Gew.-% und dessen Herstellung
US20050191339A1 (en) *	2002-08-08	2005-09-01	Beiersdorf Ag	Skin friendly active ingredient plaster based on SBC, containing at least 34 WT.% of a pharmaceutical active ingredient and production thereof
JP2004224741A (ja) *	2003-01-23	2004-08-12	Hisamitsu Pharmaceut Co Inc	ツロブテロール経皮吸収型製剤
JP4422430B2 (ja) *	2003-05-14	2010-02-24	帝國製薬株式会社	エストロゲン及び／又はプロゲストゲン含有外用貼付剤
JP4311728B2 (ja) *	2003-12-10	2009-08-12	ニチバン株式会社	経皮吸収型貼付剤
DE102004028284A1 (de) *	2004-06-11	2006-01-05	Hexal Ag	Matrixkontrolliertes transdermales therapeutisches System auf Basis eines Schmelzklebstoffs zur Anwendung von Norelgestromin
US20070062884A1 (en)	2005-08-11	2007-03-22	Board Of Regents, The University Of Texas System	N-halamines compounds as multifunctional additives
WO2007129427A1 (ja) *	2006-05-08	2007-11-15	Teikoku Seiyaku Co., Ltd.	抗認知症薬物の経皮吸収製剤
RS62297B1 (sr)	2011-11-23	2021-09-30	Therapeuticsmd Inc	Prirodne kombinovane hormonske supstitucione formulacije i terapije
US9301920B2 (en)	2012-06-18	2016-04-05	Therapeuticsmd, Inc.	Natural combination hormone replacement formulations and therapies
US10806740B2 (en)	2012-06-18	2020-10-20	Therapeuticsmd, Inc.	Natural combination hormone replacement formulations and therapies
US10806697B2 (en)	2012-12-21	2020-10-20	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en)	2012-06-18	2015-07-16	Therapeuticsmd, Inc.	Progesterone formulations having a desirable pk profile
US20130338122A1 (en)	2012-06-18	2013-12-19	Therapeuticsmd, Inc.	Transdermal hormone replacement therapies
US11266661B2 (en)	2012-12-21	2022-03-08	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en)	2012-12-21	2019-11-12	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en)	2012-12-21	2020-02-25	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en)	2012-12-21	2020-01-21	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en)	2012-12-21	2022-02-15	Therapeuticsmd, Inc.	Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en)	2012-12-21	2015-11-10	Therapeuticsmd, Inc.	Soluble estradiol capsule for vaginal insertion
RU2016143081A (ru)	2014-05-22	2018-06-26	Терапьютиксмд, Инк.	Натуральные комбинированные гормонозаместительные составы и терапии
US10328087B2 (en)	2015-07-23	2019-06-25	Therapeuticsmd, Inc.	Formulations for solubilizing hormones
US9931349B2 (en)	2016-04-01	2018-04-03	Therapeuticsmd, Inc.	Steroid hormone pharmaceutical composition
US10286077B2 (en)	2016-04-01	2019-05-14	Therapeuticsmd, Inc.	Steroid hormone compositions in medium chain oils
US11633405B2 (en)	2020-02-07	2023-04-25	Therapeuticsmd, Inc.	Steroid hormone pharmaceutical formulations

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US4299501A (en) *	1979-08-10	1981-11-10	Ortho Pharmaceutical Corporation	Continuous process for the preparation of semisolid dispersions
JPS60188315A (ja) *	1984-03-07	1985-09-25	Yamanouchi Pharmaceut Co Ltd	グリチルレチン酸配合鎮痒プラスター
US4994267A (en) *	1988-03-04	1991-02-19	Noven Pharmaceuticals, Inc.	Transdermal acrylic multipolymer drug delivery system
US5032402A (en) *	1988-10-27	1991-07-16	The University Of Kentucky Research Foundation	3-hydroxy-N-methylpyrrolidone and use as transdermal enhancer
DE69108512T2 (de) *	1990-05-17	1995-08-03	Hisamitsu Pharmaceutical Co	Estradiol enthaltende transdermale zubereitung.
US5232702A (en) *	1991-07-22	1993-08-03	Dow Corning Corporation	Silicone pressure sensitive adhesive compositons for transdermal drug delivery devices and related medical devices
JPH05331064A (ja) *	1992-05-26	1993-12-14	Sekisui Chem Co Ltd	消炎鎮痛貼付剤

1994
- 1994-03-28 FR FR9403599A patent/FR2717689B1/fr not_active Expired - Fee Related
1995
- 1995-03-15 EP EP95400574A patent/EP0674901B1/fr not_active Expired - Lifetime
- 1995-03-15 AT AT95400574T patent/ATE173618T1/de not_active IP Right Cessation
- 1995-03-15 ES ES95400574T patent/ES2128673T3/es not_active Expired - Lifetime
- 1995-03-15 DE DE69506157T patent/DE69506157T2/de not_active Expired - Fee Related
- 1995-03-15 DK DK95400574T patent/DK0674901T3/da active
- 1995-03-21 AU AU14978/95A patent/AU691558B2/en not_active Ceased
- 1995-03-21 LV LVP-95-76A patent/LV10929B/en unknown
- 1995-03-24 NO NO951126A patent/NO951126L/no not_active Application Discontinuation
- 1995-03-24 FI FI951424A patent/FI951424A7/fi unknown
- 1995-03-27 PL PL95307891A patent/PL178896B1/pl unknown
- 1995-03-27 RU RU95104225A patent/RU2110282C1/ru active
- 1995-03-27 ZA ZA952469A patent/ZA952469B/xx unknown
- 1995-03-27 CZ CZ95767A patent/CZ76795A3/cs unknown
- 1995-03-27 HU HU9500880A patent/HU219465B/hu not_active IP Right Cessation
- 1995-03-27 SK SK390-95A patent/SK39095A3/sk unknown
- 1995-03-27 CA CA002145584A patent/CA2145584A1/en not_active Abandoned
- 1995-03-27 NZ NZ270811A patent/NZ270811A/en unknown
- 1995-03-28 KR KR1019950006675A patent/KR950031057A/ko not_active Withdrawn
- 1995-03-28 JP JP7069493A patent/JPH07330609A/ja active Pending
- 1995-03-28 US US08/413,216 patent/US5580572A/en not_active Expired - Fee Related
- 1995-03-28 CN CN95103637A patent/CN1114903A/zh active Pending
1999
- 1999-02-15 GR GR980403030T patent/GR3029401T3/el unknown

Also Published As

Publication number	Publication date
FI951424A0 (fi)	1995-03-24
AU691558B2 (en)	1998-05-21
FR2717689B1 (fr)	1996-07-05
CN1114903A (zh)	1996-01-17
RU2110282C1 (ru)	1998-05-10
JPH07330609A (ja)	1995-12-19
LV10929B (en)	1996-08-20
CA2145584A1 (en)	1995-09-29
HU219465B (hu)	2001-04-28
EP0674901A1 (fr)	1995-10-04
NO951126D0 (no)	1995-03-24
DK0674901T3 (da)	1999-08-09
ZA952469B (en)	1995-12-19
PL307891A1 (en)	1995-10-02
KR950031057A (ko)	1995-12-18
DE69506157T2 (de)	1999-07-01
ATE173618T1 (de)	1998-12-15
PL178896B1 (pl)	2000-06-30
EP0674901B1 (fr)	1998-11-25
AU1497895A (en)	1995-10-05
HU9500880D0 (en)	1995-05-29
US5580572A (en)	1996-12-03
CZ76795A3 (en)	1995-10-18
ES2128673T3 (es)	1999-05-16
SK39095A3 (en)	1995-10-11
LV10929A (lv)	1995-12-20
DE69506157D1 (de)	1999-01-07
GR3029401T3 (en)	1999-05-28
FR2717689A1 (fr)	1995-09-29
HUT75238A (en)	1997-05-28
FI951424A7 (fi)	1995-09-29
NZ270811A (en)	1995-12-21

Legal Events

Date	Code	Title	Description
2001-03-05	FC2A	Withdrawal, rejection or dismissal of laid open patent application

Publication	Publication Date	Title
NO951125L (no)	1995-09-29	Transdermalt matrikssystem basert på EVA for administrasjon av et östrogen og/eller et progestogen
NO981315L (no)	1998-03-24	Transdermalt matrikssystem
KR950031057A (ko)	1995-12-18	에스트로겐 및/또는 프로게스토겐을 투여하기 위한 스티렌-이소프렌-스티렌 공중합체로 이루어진 경피성 매트릭스 시스템
IE37925L (en)	1974-01-19	17ß-HALOALKOXYCARBONYL-17Ó-OXY STEROIDS.
BR9808330A (pt)	2000-05-16	Sìntese de 2-alcoxiestradióis e composto de estradiol
DE3650265D1 (de)	1995-04-20	Makrolide Antibiotika und Verfahren zu deren Herstellung.
NO981252L (no)	1998-03-19	Transdermalt matrikssystem
AU1517088A (en)	1988-12-01	Agents for repelling insects and mites
PT79839B (en)	1986-10-23	Process for the preparation of 6,6-ethylene-15,16-methylene-3-oxi-17alpha-pregn-4-ene-21,17-carbolactones and pharmaceutical compositions therewith
WO1987004167A2 (en)	1987-07-16	Aminoglycoside steroids, a process for their preparation, their use and pharmaceutical compositions containing them
CA2078804A1 (en)	1993-04-02	Manufacture and use of novel glycosides of catechol estrogens
EP0757987A4 (en)	1997-04-16	PYRAZOLECARBOXYLIC ACID DERIVATIVE AND PLANT DISEASE CONTROL AGENT
NO932277L (no)	1993-08-20	6,7-modifiserte 11beta-aryl-4-oestrener
ES8502700A1 (es)	1985-01-16	Procedimiento para la fabricacion de derivados de tetrahidrobenzotiazol.
CA2104515A1 (en)	1995-02-21	Composition for accelerating healing of wound
WO2001018028A8 (de)	2001-06-07	Neue c-13-substituierte estra-1,3,5(10)-trien-3-yl-sulfamate, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen zur hemmung von östron sulfatase
EP0500951A4 (cs)	1994-02-02
JPS5522632A (en)	1980-02-18	Preparation of stable composition comprising prenyl ketone compound