NO951445L - Erytropoietinanaloger - Google Patents
ErytropoietinanalogerInfo
- Publication number
- NO951445L NO951445L NO951445A NO951445A NO951445L NO 951445 L NO951445 L NO 951445L NO 951445 A NO951445 A NO 951445A NO 951445 A NO951445 A NO 951445A NO 951445 L NO951445 L NO 951445L
- Authority
- NO
- Norway
- Prior art keywords
- hepo
- analogue
- glycosylation site
- sequence
- dna
- Prior art date
Links
- 102000003951 Erythropoietin Human genes 0.000 title 1
- 108090000394 Erythropoietin Proteins 0.000 title 1
- 229940105423 erythropoietin Drugs 0.000 title 1
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 title 1
- 101000987586 Homo sapiens Eosinophil peroxidase Proteins 0.000 abstract 3
- 101000920686 Homo sapiens Erythropoietin Proteins 0.000 abstract 3
- 102000044890 human EPO Human genes 0.000 abstract 3
- 230000013595 glycosylation Effects 0.000 abstract 2
- 238000006206 glycosylation reaction Methods 0.000 abstract 2
- 108020004414 DNA Proteins 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 230000008707 rearrangement Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10801693A | 1993-08-17 | 1993-08-17 | |
| PCT/US1994/009257 WO1995005465A1 (en) | 1993-08-17 | 1994-08-16 | Erythropoietin analogs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO951445D0 NO951445D0 (no) | 1995-04-12 |
| NO951445L true NO951445L (no) | 1995-06-16 |
| NO323104B1 NO323104B1 (no) | 2007-01-02 |
Family
ID=22319789
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19951445A NO323104B1 (no) | 1993-08-17 | 1995-04-12 | Analoger av humant erytropoietin, DNA-sekvenser som koder for disse, eukaryot vertscelle transfektert med DNA-sekvensene, preparat som omfatter analogene, anvendelse av analogene til okning av hematokritt, og fremgangsmate for fremstilling av analogene. |
| NO2007008C NO2007008I2 (no) | 1993-08-17 | 2007-06-29 | Analoger av humant erytropoietin,DNA-sekvenser somkoder for disse, eukaryot vertscelle transfektert med DNA-sekvensene, preparat som omfatter analoge ne, anvendelse av analogene til økning av hematokritt, og fremgangsmåte for fremstilling av analogene. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO2007008C NO2007008I2 (no) | 1993-08-17 | 2007-06-29 | Analoger av humant erytropoietin,DNA-sekvenser somkoder for disse, eukaryot vertscelle transfektert med DNA-sekvensene, preparat som omfatter analoge ne, anvendelse av analogene til økning av hematokritt, og fremgangsmåte for fremstilling av analogene. |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP0640619B2 (no) |
| JP (3) | JP2938572B2 (no) |
| KR (2) | KR100328769B1 (no) |
| CN (1) | CN1057534C (no) |
| AT (1) | ATE155796T1 (no) |
| AU (1) | AU677097B2 (no) |
| CA (1) | CA2147124C (no) |
| CZ (3) | CZ291229B6 (no) |
| DE (2) | DE69404401T3 (no) |
| DK (1) | DK0640619T4 (no) |
| ES (1) | ES2105442T5 (no) |
| FI (1) | FI117136B (no) |
| GR (1) | GR3024815T3 (no) |
| HU (1) | HU220334B (no) |
| IL (4) | IL192290A0 (no) |
| LU (1) | LU90850I2 (no) |
| LV (1) | LV10972B (no) |
| NL (1) | NL300075I2 (no) |
| NO (2) | NO323104B1 (no) |
| NZ (1) | NZ273134A (no) |
| RU (1) | RU2159814C2 (no) |
| SI (1) | SI0640619T2 (no) |
| SK (1) | SK282003B6 (no) |
| UA (1) | UA49793C2 (no) |
| WO (1) | WO1995005465A1 (no) |
| ZA (1) | ZA946122B (no) |
Families Citing this family (245)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7217689B1 (en) | 1989-10-13 | 2007-05-15 | Amgen Inc. | Glycosylation analogs of erythropoietin |
| FR2686899B1 (fr) | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant. |
| US5614184A (en) * | 1992-07-28 | 1997-03-25 | New England Deaconess Hospital | Recombinant human erythropoietin mutants and therapeutic methods employing them |
| US5696250A (en) | 1995-02-15 | 1997-12-09 | Amgen Inc. | DNA encoding megakaryocyte growth and development factor analogs |
| US5989538A (en) * | 1995-02-15 | 1999-11-23 | Amgen Inc. | Mpl ligand analogs |
| EP0854882A1 (en) * | 1995-10-09 | 1998-07-29 | PHARMACIA & UPJOHN COMPANY | An acceptor polypeptide for an n-acetylgalactosaminyltransferase |
| KR100400637B1 (ko) * | 1996-02-06 | 2004-03-10 | 씨제이 주식회사 | 생물학적으로유용한펩타이드 |
| EP0888385B1 (en) | 1996-03-14 | 2003-08-20 | Genentech, Inc. | Gdnf receptor and uses thereof |
| US5952226A (en) * | 1996-11-05 | 1999-09-14 | Modex Therapeutiques | Hypoxia responsive EPO producing cells |
| DE69726571T2 (de) * | 1997-09-01 | 2004-11-04 | Aventis Pharma Deutschland Gmbh | Rekombinantes humanes Erythropoietin mit vorteilhaftem Glykosylierungsmuster |
| PT1037927E (pt) | 1997-12-08 | 2004-10-29 | Emd Lexigen Res Ct Corp | Proteinas de fusao heterodimericas uteis para imunoterapia de abordagem selectiva e estimulacao imunologica geral |
| DE69933216T2 (de) | 1998-06-15 | 2007-09-20 | GTC Biotherapeutics, Inc., Framingham | Erythropoietin-analog-menschliches serum-albumin fusionsprotein |
| ATE355303T1 (de) * | 1998-10-23 | 2006-03-15 | Amgen Inc | Methoden und zusammensetzungen zur prävention und behandlung der anämie |
| US7304150B1 (en) | 1998-10-23 | 2007-12-04 | Amgen Inc. | Methods and compositions for the prevention and treatment of anemia |
| DE19857609A1 (de) | 1998-12-14 | 2000-06-15 | Hannelore Ehrenreich | Verwendung von Erythropoietin zur Behandlung von cerebralen Ischämien des Menschen |
| ATE323766T1 (de) * | 1999-02-12 | 2006-05-15 | Amgen Inc | Glykosylierte leptinzusammensetzungen und zugehörige verfahren |
| US7345019B1 (en) | 1999-04-13 | 2008-03-18 | The Kenneth S. Warren Institute, Inc. | Modulation of excitable tissue function by peripherally administered erythropoietin |
| US7410941B1 (en) | 1999-04-13 | 2008-08-12 | The Kenneth S. Warren Institute, Inc. | Methods for treatment of neurodegenerative conditions by peripherally administered erythropoietin |
| US8236561B2 (en) | 1999-04-15 | 2012-08-07 | Crucell Holland B.V. | Efficient production of IgA in recombinant mammalian cells |
| US7604960B2 (en) | 1999-04-15 | 2009-10-20 | Crucell Holland B.V. | Transient protein expression methods |
| US7297680B2 (en) | 1999-04-15 | 2007-11-20 | Crucell Holland B.V. | Compositions of erythropoietin isoforms comprising Lewis-X structures and high sialic acid content |
| US6855544B1 (en) | 1999-04-15 | 2005-02-15 | Crucell Holland B.V. | Recombinant protein production in a human cell |
| US6555343B1 (en) | 1999-05-07 | 2003-04-29 | Genentech Inc. | Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same |
| US6831060B2 (en) | 1999-05-07 | 2004-12-14 | Genentech, Inc. | Chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same |
| AU766507B2 (en) * | 1999-05-07 | 2003-10-16 | Genentech Inc. | Novel chimpanzee erythropoietin (CHEPO) polypeptides and nucleic acids encoding the same |
| RU2232163C2 (ru) * | 1999-07-02 | 2004-07-10 | Ф.Хоффманн-Ля Рош Аг | Конъюгаты эритропоэтина и полиэтиленгликоля, фармацевтические композиции (варианты), способ профилактического и/или терапевтического лечения нарушений и способ получения коньюгата или композиции |
| JO2291B1 (en) * | 1999-07-02 | 2005-09-12 | اف . هوفمان لاروش ايه جي | Erythropoietin derivatives |
| CZ299516B6 (cs) * | 1999-07-02 | 2008-08-20 | F. Hoffmann-La Roche Ag | Konjugát erythropoetinového glykoproteinu, zpusobjeho výroby a použití a farmaceutická kompozice sjeho obsahem |
| SK782002A3 (en) | 1999-07-21 | 2003-08-05 | Lexigen Pharm Corp | FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens |
| US7067110B1 (en) | 1999-07-21 | 2006-06-27 | Emd Lexigen Research Center Corp. | Fc fusion proteins for enhancing the immunogenicity of protein and peptide antigens |
| BR0013231A (pt) | 1999-08-09 | 2002-07-23 | Lexigen Pharm Corp | Complexos citocina-anticorpo múltiplos |
| EP1228214A2 (en) | 1999-11-12 | 2002-08-07 | MERCK PATENT GmbH | Erythropoietin forms with improved properties |
| US7192759B1 (en) | 1999-11-26 | 2007-03-20 | Crucell Holland B.V. | Production of vaccines |
| US7527961B2 (en) | 1999-11-26 | 2009-05-05 | Crucell Holland B.V. | Production of vaccines |
| US7521220B2 (en) | 1999-11-26 | 2009-04-21 | Crucell Holland B.V. | Production of vaccines |
| JP5179689B2 (ja) | 2000-02-11 | 2013-04-10 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 抗体ベース融合タンパク質の循環系内半減期の増強 |
| US6586398B1 (en) * | 2000-04-07 | 2003-07-01 | Amgen, Inc. | Chemically modified novel erythropoietin stimulating protein compositions and methods |
| EP1274720A4 (en) | 2000-04-12 | 2004-08-18 | Human Genome Sciences Inc | FUSION PROTEINS CONTAINING ALBUMIN |
| WO2001081405A2 (en) * | 2000-04-21 | 2001-11-01 | Amgen Inc. | Methods and compositions for the prevention and treatment of anemia |
| JP3967594B2 (ja) * | 2000-05-15 | 2007-08-29 | エフ.ホフマン−ラ ロシュ アーゲー | 新しい薬剤組成物 |
| US7259146B2 (en) | 2000-05-26 | 2007-08-21 | Ortho-Mcneil Pharmaceutical, Inc. | Neuroprotective peptides |
| JP5390055B2 (ja) | 2000-06-29 | 2014-01-15 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング | 免疫サイトカインの取り込み増強剤との併用治療による抗体−サイトカイン融合タンパク質媒介免疫応答の増強 |
| JP5490972B2 (ja) | 2000-08-04 | 2014-05-14 | 中外製薬株式会社 | タンパク質注射製剤 |
| JP5485489B2 (ja) | 2000-08-11 | 2014-05-07 | 中外製薬株式会社 | 抗体含有安定化製剤 |
| ATE320449T1 (de) * | 2000-12-11 | 2006-04-15 | Cheil Jedang Corp | Fusionsprotein mit verbesserter in vivo erythropoietinwirkung |
| KR101229995B1 (ko) * | 2000-12-11 | 2013-02-06 | 씨제이 주식회사 | 생체내 에리스로포이에틴 활성이 증진된 융합단백질 |
| CA2431964C (en) | 2000-12-20 | 2013-09-10 | F. Hoffmann-La Roche Ag | Conjugates of erythropoietin (pep) with polyethylene glycol (peg) |
| US6531121B2 (en) | 2000-12-29 | 2003-03-11 | The Kenneth S. Warren Institute, Inc. | Protection and enhancement of erythropoietin-responsive cells, tissues and organs |
| US7767643B2 (en) | 2000-12-29 | 2010-08-03 | The Kenneth S. Warren Institute, Inc. | Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs |
| PA8536201A1 (es) | 2000-12-29 | 2002-08-29 | Kenneth S Warren Inst Inc | Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina |
| US20030072737A1 (en) | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
| NZ548578A (en) | 2001-02-02 | 2008-03-28 | Ortho Mcneil Pharm Inc | Treatment of neurological dysfunction comprising fructopyranose sulfamates and erythropoietin |
| HUP0303428A2 (hu) | 2001-03-07 | 2004-01-28 | Merck Patent Gmbh. | Expressziós eljárás hibrid izotípusú antitestcsoportot tartalmazó fehérjékhez |
| EP3088412B1 (en) | 2001-03-09 | 2021-05-05 | Chugai Seiyaku Kabushiki Kaisha | Protein purification method |
| DE10112825A1 (de) | 2001-03-16 | 2002-10-02 | Fresenius Kabi De Gmbh | HESylierung von Wirkstoffen in wässriger Lösung |
| WO2002079415A2 (en) | 2001-03-30 | 2002-10-10 | Lexigen Pharmaceuticals Corp. | Reducing the immunogenicity of fusion proteins |
| FR2823220B1 (fr) * | 2001-04-04 | 2003-12-12 | Genodyssee | Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo) |
| EP1382964A4 (en) | 2001-04-17 | 2009-06-10 | Chugai Pharmaceutical Co Ltd | METHOD FOR TENSID QUANTIFICATION |
| KR100900166B1 (ko) | 2001-05-03 | 2009-06-02 | 메르크 파텐트 게엠베하 | 재조합 종양 특이적 항체 및 이들의 용도 |
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| US7173003B2 (en) | 2001-10-10 | 2007-02-06 | Neose Technologies, Inc. | Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF |
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| US6818613B2 (en) | 2001-11-07 | 2004-11-16 | Ortho-Mcneil Pharmaceutical, Inc. | Aqueous sustained-release formulations of proteins |
| US7232797B2 (en) | 2001-11-28 | 2007-06-19 | Ortho-Mcneil Pharmaceutical, Inc. | Erythropoietin dosing regimen for treating anemia |
| KR100467750B1 (ko) * | 2001-11-29 | 2005-01-24 | 씨제이 주식회사 | 생체내 에리스로포이에틴 활성이 증진된 융합단백질 |
| KR100467751B1 (ko) * | 2001-12-03 | 2005-01-24 | 씨제이 주식회사 | 생체내 에리스로포이에틴 활성이 증진된 융합단백질 |
| ATE542137T1 (de) | 2001-12-04 | 2012-02-15 | Merck Patent Gmbh | Immunocytokine mit modulierter selektivität |
| JP4480398B2 (ja) | 2001-12-07 | 2010-06-16 | クルセル ホランド ベー ヴェー | ウイルス、ウイルス分離株及びワクチンの製造方法 |
| PT1463751E (pt) | 2001-12-21 | 2013-08-26 | Human Genome Sciences Inc | Proteínas de fusão de albumina |
| DE10209822A1 (de) | 2002-03-06 | 2003-09-25 | Biotechnologie Ges Mittelhesse | Kopplung niedermolekularer Substanzen an ein modifiziertes Polysaccharid |
| DE10209821A1 (de) | 2002-03-06 | 2003-09-25 | Biotechnologie Ges Mittelhesse | Kopplung von Proteinen an ein modifiziertes Polysaccharid |
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| US20030191056A1 (en) | 2002-04-04 | 2003-10-09 | Kenneth Walker | Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins |
| US20040122216A1 (en) * | 2002-07-01 | 2004-06-24 | Jacob Nielsen | Recombinant tissue protective cytokines and encoding nucleic acids thereof for protection, restoration, and enhancement of responsive cells, tissues, and organs |
| AU2003246486A1 (en) * | 2002-07-19 | 2004-02-09 | Cangene Corporation | Pegylated erythropoietic compounds |
| DE10234192B4 (de) | 2002-07-26 | 2009-11-26 | Epoplus Gmbh Co.Kg | Verwendung von Erythropoetin |
| AU2003257536A1 (en) | 2002-08-27 | 2004-03-19 | Chugai Seiyaku Kabushiki Kaisha | Method of stabilizing protein solution preparation |
| US7459435B2 (en) | 2002-08-29 | 2008-12-02 | Hoffmann-La Roche Inc. | Treatment of disturbances of iron distribution |
| CA2498319A1 (en) | 2002-09-09 | 2004-03-18 | Nautilus Biotech | Rational evolution of cytokines for higher stability, the cytokines and encoding nucleic acid molecules |
| ES2626268T3 (es) | 2002-09-11 | 2017-07-24 | Chugai Seiyaku Kabushiki Kaisha | Método de purificación de proteínas |
| DE20321793U1 (de) | 2002-09-11 | 2010-06-02 | Fresenius Kabi Deutschland Gmbh | Hydroxyalkylstärke-Derivate |
| MXPA05002594A (es) | 2002-09-11 | 2005-05-27 | Fresenius Kabi Gmbh | Derivados de polipeptidos con hidroxialquilalmidon, especialmente derivados de eritropoyetina con hidroxialquilalmidon. |
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| AU2003301332B2 (en) * | 2002-10-17 | 2008-06-12 | Pharming Intellectual Property B.V. | Protein modification |
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| US9005625B2 (en) | 2003-07-25 | 2015-04-14 | Novo Nordisk A/S | Antibody toxin conjugates |
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| WO2005014655A2 (en) | 2003-08-08 | 2005-02-17 | Fresenius Kabi Deutschland Gmbh | Conjugates of hydroxyalkyl starch and a protein |
| JP2007517769A (ja) | 2003-09-29 | 2007-07-05 | ウォーレン ファーマシューティカルズ,インコーポレーテッド | 敗血症および癒着形成の治療および予防のための組織保護性サイトカイン |
| US20080305992A1 (en) | 2003-11-24 | 2008-12-11 | Neose Technologies, Inc. | Glycopegylated erythropoietin |
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- 1994-08-15 IL IL110669A patent/IL110669A/en not_active IP Right Cessation
- 1994-08-16 SK SK502-95A patent/SK282003B6/sk unknown
- 1994-08-16 KR KR1019950701453A patent/KR100328769B1/ko not_active Expired - Lifetime
- 1994-08-16 EP EP94112732A patent/EP0640619B2/en not_active Expired - Lifetime
- 1994-08-16 AT AT94112732T patent/ATE155796T1/de active
- 1994-08-16 WO PCT/US1994/009257 patent/WO1995005465A1/en not_active Ceased
- 1994-08-16 CZ CZ1995917A patent/CZ291229B6/cs not_active IP Right Cessation
- 1994-08-16 CA CA002147124A patent/CA2147124C/en not_active Expired - Lifetime
- 1994-08-16 JP JP7507153A patent/JP2938572B2/ja not_active Expired - Lifetime
- 1994-08-16 AU AU76327/94A patent/AU677097B2/en not_active Expired
- 1994-08-16 DE DE69404401T patent/DE69404401T3/de not_active Expired - Lifetime
- 1994-08-16 HU HU9501435A patent/HU220334B/hu active Protection Beyond IP Right Term
- 1994-08-16 DE DE2001199059 patent/DE10199059I2/de active Active
- 1994-08-16 SI SI9430078T patent/SI0640619T2/xx unknown
- 1994-08-16 NZ NZ273134A patent/NZ273134A/en not_active IP Right Cessation
- 1994-08-16 DK DK94112732T patent/DK0640619T4/da active
- 1994-08-16 UA UA95058432A patent/UA49793C2/uk unknown
- 1994-08-16 RU RU95115239/14A patent/RU2159814C2/ru active
- 1994-08-16 ES ES94112732T patent/ES2105442T5/es not_active Expired - Lifetime
-
1995
- 1995-04-12 NO NO19951445A patent/NO323104B1/no not_active IP Right Cessation
- 1995-04-13 FI FI951792A patent/FI117136B/fi not_active IP Right Cessation
- 1995-04-15 KR KR1019957001453A patent/KR960701994A/ko active Pending
- 1995-04-17 LV LVP-95-99A patent/LV10972B/en unknown
-
1997
- 1997-09-22 GR GR970402449T patent/GR3024815T3/el unknown
-
1998
- 1998-08-24 JP JP25324498A patent/JP3664590B2/ja not_active Expired - Lifetime
-
2000
- 2000-05-16 IL IL13618900A patent/IL136189A0/xx unknown
- 2000-05-16 IL IL13618800A patent/IL136188A0/xx unknown
-
2001
- 2001-02-06 CZ CZ2001462A patent/CZ291342B6/cs not_active IP Right Cessation
- 2001-02-06 CZ CZ2001463A patent/CZ291343B6/cs not_active IP Right Cessation
- 2001-11-07 LU LU90850C patent/LU90850I2/fr unknown
- 2001-12-06 NL NL300075C patent/NL300075I2/nl unknown
-
2004
- 2004-06-25 JP JP2004188815A patent/JP3664723B2/ja not_active Expired - Lifetime
-
2007
- 2007-06-29 NO NO2007008C patent/NO2007008I2/no unknown
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