NO951899L - Pyran-2-oner ig 5,6-dihydropyran-2-oner som kan anvendes for behandling av HIV og andre retrovirus - Google Patents

Pyran-2-oner ig 5,6-dihydropyran-2-oner som kan anvendes for behandling av HIV og andre retrovirus

Info

Publication number: NO951899L
Authority: NO; Norway
Prior art keywords: ones; pyran; dihydropyran; retroviruses; treat hiv
Prior art date: 1992-11-13

Application number

NO951899A

Other languages

English (en)

Other versions

NO951899D0 (no

NO319914B1 (no

Inventor

Suvit Thaisrivongs

Chih-Ping Yang

Joseph Walter Strohbach

Steven Ronald Turner

Donna Lee Romero

Louis L Skaletzky

Paul Adrian Aristoff

Ronald B Gammill

Paul D Johnsen

Harvey Irving Skulnick

Richard C Piper

Ruben A Tommasi

Qingwei Zhang

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-11-13

Filing date

1995-05-12

Publication date

1995-07-12

1995-05-12 Application filed by Upjohn Co filed Critical Upjohn Co

1995-05-12 Publication of NO951899D0 publication Critical patent/NO951899D0/no

1995-07-12 Publication of NO951899L publication Critical patent/NO951899L/no

2005-10-03 Publication of NO319914B1 publication Critical patent/NO319914B1/no

Links

QBDAFARLDLCWAT-UHFFFAOYSA-N 2,3-dihydropyran-6-one Chemical class O=C1OCCC=C1 QBDAFARLDLCWAT-UHFFFAOYSA-N 0.000 title 1
ZPSJGADGUYYRKE-UHFFFAOYSA-N 2H-pyran-2-one Chemical class O=C1C=CC=CO1 ZPSJGADGUYYRKE-UHFFFAOYSA-N 0.000 title 1
241001430294 unidentified retrovirus Species 0.000 title 1
206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract 2
208000004403 Prostatic Hyperplasia Diseases 0.000 abstract 2
150000000464 2H-pyran-2-ones Chemical class 0.000 abstract 1
208000002874 Acne Vulgaris Diseases 0.000 abstract 1
201000004384 Alopecia Diseases 0.000 abstract 1
206010020112 Hirsutism Diseases 0.000 abstract 1
206010060862 Prostate cancer Diseases 0.000 abstract 1
208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
206010039792 Seborrhoea Diseases 0.000 abstract 1
206010000496 acne Diseases 0.000 abstract 1
231100000360 alopecia Toxicity 0.000 abstract 1
208000008742 seborrheic dermatitis Diseases 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Virology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Tropical Medicine & Parasitology (AREA)
AIDS & HIV (AREA)
Diabetes (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Reproductive Health (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Saccharide Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Plant Substances (AREA)
Cosmetics (AREA)

NO19951899A 1992-11-13 1995-05-12 Pyran-2-oner og 5,6-dihydropyran-2-oner, anvendelse derav til fremstilling av medikamenter som kan anvendes for behandling av HIV og inhibering av andre retrovirus, farmasoytiske preparater som omfatter forbindelsene, fremgangsmate for fremstilling av et pyran-2-on, samt forbindelse som er et mellomprodukt i fremgangsmaten. NO319914B1 (no)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US97534392A	1992-11-13	1992-11-13
US9087693A	1993-07-13	1993-07-13
US13064193A	1993-10-01	1993-10-01
PCT/US1993/010645 WO1994011361A1 (en)	1992-11-13	1993-11-09	Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating hiv and other retroviruses

Publications (3)

Publication Number	Publication Date
NO951899D0 NO951899D0 (no)	1995-05-12
NO951899L true NO951899L (no)	1995-07-12
NO319914B1 NO319914B1 (no)	2005-10-03

Family

ID=27376682

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19951899A NO319914B1 (no)	1992-11-13	1995-05-12	Pyran-2-oner og 5,6-dihydropyran-2-oner, anvendelse derav til fremstilling av medikamenter som kan anvendes for behandling av HIV og inhibering av andre retrovirus, farmasoytiske preparater som omfatter forbindelsene, fremgangsmate for fremstilling av et pyran-2-on, samt forbindelse som er et mellomprodukt i fremgangsmaten.

Country Status (26)

Country	Link
EP (2)	EP1203770B1 (no)
JP (1)	JP3583127B2 (no)
KR (1)	KR100314975B1 (no)
CN (1)	CN1040321C (no)
AT (2)	ATE290531T1 (no)
AU (1)	AU687368B2 (no)
BR (1)	BR9307451A (no)
CA (1)	CA2145661C (no)
CZ (1)	CZ291853B6 (no)
DE (2)	DE69332292T2 (no)
DK (2)	DK0668860T3 (no)
ES (2)	ES2237624T3 (no)
FI (1)	FI120399B (no)
GE (1)	GEP20094660B (no)
HU (1)	HU228126B1 (no)
IL (1)	IL107556A (no)
LV (1)	LV13088B (no)
MY (1)	MY119031A (no)
NO (1)	NO319914B1 (no)
NZ (1)	NZ258013A (no)
PL (1)	PL178653B1 (no)
PT (2)	PT668860E (no)
RU (1)	RU2134691C1 (no)
SK (1)	SK285001B6 (no)
WO (1)	WO1994011361A1 (no)
ZA (1)	ZA938019B (no)

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FI962019A7 (fi) *	1993-11-19	1996-05-20	Parke Davis & Co	Pyronijohdannaiset proteaasi-inhibiittoreina ja antiviraalisina ainein a
DE69433705T2 (de) *	1993-11-19	2005-03-10	Parke, Davis & Company	5,6-Dihydropyronderivate als Proteaseinhibitoren und Antiviralmittel
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JPH11503416A (ja) *	1995-03-20	1999-03-26	ファルマシア・アンド・アップジョン・カンパニー	Ｈｉｖおよび他のレトロウイルス病を治療するのに有用な置換テトロン酸
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FI113942B (fi) *	2000-08-18	2004-07-15	Control Ox Oy	Kasviperäisten fenolisten yhdisteiden käyttö valmistettaessa klamydiainfektion hoidossa ja ennaltaehkäisyssä käyttökelpoista farmaseuttista valmistetta, terveyteen myönteisesti vaikuttavaa ravintoainekoostumusta tai koostumusta lisättäväksi tällaisiin elintarvikkeisiin
EP1281399A3 (en) *	2001-08-01	2004-02-11	Warner-Lambert Company	Dual inhibitors of wax ester and cholesteryl ester synthesis for inhibiting sebum production
DOP2003000641A (es)	2002-05-10	2003-11-15	Pfizer	Inhibidores de las arn polimerasa dependiente de arn del virus de las hepatitis c y composiciones y tratamiento que los usan
RU2236852C1 (ru) *	2003-06-23	2004-09-27	Закрытое акционерное общество "ДЕСКО"	Средство для ингибирования репродукции оболоченных вирусов, способ его получения, фармацевтическая композиция и способ ингибирования вирусных инфекций
CN101693664A (zh)	2003-10-24	2010-04-14	隆萨股份公司	6,6,6-三卤-3,5-二氧代己酸酯的制备方法
HRP20110845T1 (hr) *	2006-06-16	2011-12-31	Pharma Mar	Antitumorski dihidropiran-2-onski spojevi
PT2231633E (pt)	2007-12-20	2014-01-20	Pharma Mar Sa	Compostos antitumorais
DE102008055916A1 (de)	2008-11-05	2010-05-06	Clariant International Limited	Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Allylalkoholen und ihre Verwendung
DE102008055914A1 (de)	2008-11-05	2010-05-06	Clariant International Limited	Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Acroleinen und ihre Verwendung
WO2010051883A1 (de)	2008-11-05	2010-05-14	Clariant International Ltd	Verfahren zur herstellung von dialkylphosphinsäuren, -estern und -salzen mittels allylalkoholen/acroleinen und ihre verwendung
DE102008056339A1 (de)	2008-11-07	2010-05-12	Clariant International Limited	Verfahren zur Herstellung von mono-aminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung
EP2352740B1 (de)	2008-11-07	2014-09-24	Clariant Finance (BVI) Limited	Verfahren zur herstellung von dialkylphosphinsäuren, -estern und -salzen mittels acrylsäurederivaten und ihre verwendung
DE102008056341A1 (de)	2008-11-07	2010-05-12	Clariant International Limited	Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Acrylnitrilen und ihre Verwendung
DE102008056342A1 (de)	2008-11-07	2010-05-12	Clariant International Limited	Verfahren zur Herstellung von Dialkylphosphinsäuren, -estern und -salzen mittels Acrylnitrilen und ihre Verwendung
EP2367835B1 (de)	2008-11-11	2013-12-11	Clariant Finance (BVI) Limited	Verfahren zur herstellung von mono-allylfunktionalisierten dialkylphosphinsäuren, deren salze und ester mit allylischen verbindungen und ihre verwendung
DE102008060036A1 (de) *	2008-12-02	2010-06-10	Clariant International Limited	Verfahren zur Herstellung von mono-carboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylester einer Carbonsäure und ihre Verwendung
DE102008060035A1 (de)	2008-12-02	2010-06-10	Clariant International Limited	Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylester einer Carbonsäure und ihre Verwendung
DE102008060535A1 (de) *	2008-12-04	2010-06-10	Clariant International Limited	Verfahren zur Herstellung von mono-carboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylether und ihre Verwendung
KR101697948B1 (ko)	2008-12-18	2017-01-19	클라리언트 파이넌스 (비브이아이)리미티드	아세틸렌을 사용하는 에틸렌디알킬포스핀산, 에틸렌디알킬포스핀산 에스테르 및 에틸렌디알킬포스핀산 염의 제조방법 및 이의 용도
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DE102008063642A1 (de) *	2008-12-18	2010-06-24	Clariant International Limited	Verfahren zur Herstellung von monocarboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Alkylenoxiden und ihre Verwendung
DE102008063668A1 (de)	2008-12-18	2010-07-01	Clariant International Limited	Verfahren zur Herstellung von Alkylphosponsäuren, -estern und -salzen mittels Oxidation von Alkylphosphonigsäuren und ihre Verwendung
DE102008064012A1 (de)	2008-12-19	2010-06-24	Clariant International Limited	Halogenfreie Addukte von Alkylphosphonigsäurederivaten und diesterbildenden Olefinen, halogenfreie Verfahren zu deren Herstellung und ihre Verwendung
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1993
- 1993-10-27 ZA ZA938019A patent/ZA938019B/xx unknown
- 1993-11-09 DK DK94900546T patent/DK0668860T3/da active
- 1993-11-09 AT AT02002073T patent/ATE290531T1/de active
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- 1993-11-09 JP JP51221794A patent/JP3583127B2/ja not_active Expired - Lifetime
- 1993-11-09 AU AU55493/94A patent/AU687368B2/en not_active Expired
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Publication number	Publication date
CA2145661C (en)	2008-04-01
PL178653B1 (pl)	2000-05-31
BR9307451A (pt)	1999-08-31
CN1040321C (zh)	1998-10-21
DK1203770T3 (da)	2005-05-23
PL308998A1 (en)	1995-09-18
RU95112465A (ru)	1997-03-20
FI952302A0 (fi)	1995-05-11
DE69332292T2 (de)	2003-05-28
ZA938019B (en)	1995-04-28
KR100314975B1 (ko)	2002-02-28
SK285001B6 (sk)	2006-04-06
HU228126B1 (en)	2012-12-28
EP0668860B1 (en)	2002-09-11
RU2134691C1 (ru)	1999-08-20
EP1203770B1 (en)	2005-03-09
CZ107895A3 (en)	1995-12-13
IL107556A0 (en)	1994-02-27
PT668860E (pt)	2003-01-31
CA2145661A1 (en)	1994-05-26
JPH08503216A (ja)	1996-04-09
MY119031A (en)	2005-03-31
JP3583127B2 (ja)	2004-10-27
NO951899D0 (no)	1995-05-12
HUT71558A (en)	1995-12-28
CN1090279A (zh)	1994-08-03
DK0668860T3 (da)	2003-01-20
EP1203770A1 (en)	2002-05-08
IL107556A (en)	2001-08-08
NZ258013A (en)	1997-02-24
CZ291853B6 (cs)	2003-06-18
GEP20094660B (en)	2009-03-25
LV13088B (en)	2004-01-20
DE69333771T2 (de)	2006-04-06
WO1994011361A1 (en)	1994-05-26
ATE223910T1 (de)	2002-09-15
ES2182837T3 (es)	2003-03-16
FI952302L (fi)	1995-05-11
DE69333771D1 (de)	2005-04-14
SK61695A3 (en)	1995-10-11
DE69332292D1 (de)	2002-10-17
HU9501411D0 (en)	1995-06-28
AU5549394A (en)	1994-06-08
NO319914B1 (no)	2005-10-03
ES2237624T3 (es)	2005-08-01
PT1203770E (pt)	2005-05-31
AU687368B2 (en)	1998-02-26
FI120399B (fi)	2009-10-15
ATE290531T1 (de)	2005-03-15
EP0668860A1 (en)	1995-08-30
KR950704290A (ko)	1995-11-17

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2014-01-13	MK1K	Patent expired

Publication	Publication Date	Title
NO951899D0 (no)	1995-05-12	Pyran-2-oner ig 5,6-dihydropyran-2-oner som kan anvendes for behandling av HIV og andre retrovirus
NO961575D0 (no)	1996-04-19	16-substituerte-4-aza-androstan 5 hibitorer
NO20002409L (no)	2000-06-27	FremgangsmÕte for Õ produsere arsen trioksyd formuleringer og metoder for Õ behandle cancer ved Õ bruke arsen trioksyd eller melarsoprol
TR199801195T2 (xx)	1998-10-21	Tedavide yararl� kinolin ve kinozilin bile�ikleri.
MY138240A (en)	2009-05-29	Method of treating androgenic alopecia with 5- alpha reductase inhibitors.
LV12103A (lv)	1998-08-20	5-alfa-reduktazes inhibitora pielietojums androgenas alopecijas arstesanai
FI931765A7 (fi)	1993-10-21	Steroidijohdannaisia eturauhasen liikakasvun käsittelyyn, niiden valmistus ja käytöt
ATE178795T1 (de)	1999-04-15	7-substituierte-4-aza-steroid-derivate als 5- alpha-reductase-hemmer
EP0641208A4 (en)	1995-08-30	4-AZASTEROIDS AS 5-ALPHA REDUCTASE.
HU9501286D0 (en)	1995-06-28	Methods and compositions of (+) doxazosin for the treatment of benign prostatic hyperplasia and atherosclerosis
LV12721A (lv)	2001-09-20	17-beta-carboxanilides of 4-aza-5-alpha-androstan-3-ones as 5-alpha-reductase inhibitors
ATE198274T1 (de)	2001-01-15	17 beta-aryl-4-aza-steroidderivate
IT1251772B (it)	1995-05-24	Processo per l'ossidazione di materiali organici con perossido di idrogeno in condizioni di irraggiamento in fase acquosa
MY108848A (en)	1996-11-30	Compositions and method of treating depigmentation disorders.
KR950700746A (ko)	1995-02-20	양성 전립선 비대를 치료하는 조성물 및 방법(Compositions and Methods For Treating Benign Prostatic Hypertrophy)
GR851409B (no)	1985-11-25
BR9203266A (pt)	1993-04-06	Composto,formulacao farmaceutica,processo para inibir 5alfa-reductase,processos para tratar hiperplasia benigna da prostata,seborreia e alopecia androgenica
AU5457694A (en)	1994-05-24	Methods and compositions of (-) doxazosin for the treatment of benign prostatic hyperplasia and atherosclerosis
NO975838L (no)	1998-01-12	Melatoninagonister for behandling av godartet prostatisk hyperplasi
HK1012275A (en)	1999-07-30	Compositions and methods for treating benign prostatic hypertrophy
AU6374798A (en)	1998-06-18	Methods and compositions of (+) doxazosin for the treatment of hypertension and benign prostatic hyperplasia
UA34374A (uk)	2001-02-15	Спосіб лікування виразкової хвороби дванадцятипалої кишки