NO952650L - Nye peptider - Google Patents
Nye peptiderInfo
- Publication number
- NO952650L NO952650L NO952650A NO952650A NO952650L NO 952650 L NO952650 L NO 952650L NO 952650 A NO952650 A NO 952650A NO 952650 A NO952650 A NO 952650A NO 952650 L NO952650 L NO 952650L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- phe
- cooh
- amino acid
- formula
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
- C07K14/70—Enkephalins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Crystallography & Structural Chemistry (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Transplantation (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Forbindelser av formel (1) samt fremgangsmåter for deres fremstilling, deres farmasøytiske preparater og deres anvendelse. Forbindelsene av formel (I) er nyttige i terapi, spesielt som analgetika og som immunsuppressive midler. R3, R4, RS, Rg er alle H eller R4 og RS er begge H og R3 og Rg er begge lavere alkylgrupper eller R3, R$. Rg er alle H og R4 er F. Cl. Br. OH, NH2 eller N02; R? er C = O eller CH2; Rg er H eller en lavere alkylgruppe: RQ er (II), hvor m er 0-2 eller (HI) eller (IV) eller (V) eller (VI) eller (VII) eller (VHI) hvor RIO er H. F. Cl, Br eller I og m er 0-2: RI \ er OH, NH2 eller (IX), hvor R12 er H, NO2- F. Cl, Br eller I. m er 0-2. Rj3 er COOH. CONHo. CH2OH, eller en hvilken som helst ytterligere aminosyre eller peptidsegmem. eller RU er (X) hvor Ri4 er COOH. CONH2> CC^OH, eller en hvilken som helst ytter- ligere aminosyre eller peptidsegmem: med unntakelse av de forbindelser hvor R!, R2, RS, R4- RS- Re og Rg alle er H, R-; er C = O og Rg er (XI) og RU er Phe-OH, Phe-NH2, OH eller NH2.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9300012A SE9300012D0 (sv) | 1993-01-05 | 1993-01-05 | New peptides |
| PCT/SE1993/001090 WO1994015959A1 (en) | 1993-01-05 | 1993-12-20 | New peptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO952650D0 NO952650D0 (no) | 1995-07-04 |
| NO952650L true NO952650L (no) | 1995-08-30 |
Family
ID=20388466
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO952650A NO952650L (no) | 1993-01-05 | 1995-07-04 | Nye peptider |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US5602099A (no) |
| EP (1) | EP0678099A1 (no) |
| JP (1) | JPH08505386A (no) |
| KR (1) | KR960700269A (no) |
| CN (1) | CN1096515A (no) |
| AP (1) | AP508A (no) |
| AU (1) | AU681372B2 (no) |
| CA (1) | CA2152380A1 (no) |
| CZ (1) | CZ171195A3 (no) |
| EE (1) | EE9400326A (no) |
| FI (1) | FI953302L (no) |
| HU (1) | HUT72597A (no) |
| IL (1) | IL108169A0 (no) |
| IS (1) | IS4115A (no) |
| LV (1) | LV10962B (no) |
| MX (1) | MX9400255A (no) |
| NO (1) | NO952650L (no) |
| NZ (1) | NZ259597A (no) |
| PL (1) | PL309778A1 (no) |
| SE (1) | SE9300012D0 (no) |
| SI (1) | SI9400005A (no) |
| SK (1) | SK83995A3 (no) |
| WO (1) | WO1994015959A1 (no) |
| YU (1) | YU394A (no) |
| ZA (1) | ZA9455B (no) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU221092B1 (en) * | 1993-12-23 | 2002-08-28 | Novo Nordisk As | Compounds with growth hormone releasing properties |
| IS4261A (is) * | 1994-02-21 | 1995-08-22 | Astra Aktiebolag | Nýir peptíð-ópíóíðar til meðhöndlunar á verkjum og notkun þeirra |
| SE9503924D0 (sv) * | 1995-08-18 | 1995-11-07 | Astra Ab | Novel opioid peptides |
| IL114046A0 (en) * | 1994-06-20 | 1995-10-31 | Astra Ab | New opioid peptide antagonists |
| US6184208B1 (en) | 1994-06-29 | 2001-02-06 | Immunotech Developments Inc. | Peptide, a method for its preparation and a pharmaceutical composition containing the peptide |
| RU2067000C1 (ru) * | 1994-06-29 | 1996-09-27 | Владислав Исакович Дейгин | Пептид и способ его получения |
| SE9402880D0 (sv) * | 1994-08-30 | 1994-08-30 | Astra Ab | New peptide derivatives |
| US5780589A (en) * | 1994-11-30 | 1998-07-14 | The United States Of America As Represented By The Department Of Health And Human Services | Ultraselective opioidmimetic peptides and pharmacological and therapeutic uses thereof |
| EP0837857A4 (en) * | 1995-03-29 | 1998-08-05 | Merck & Co Inc | Inhibitors of farnesyl-protein transferase |
| AU708620B2 (en) * | 1995-03-29 | 1999-08-05 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| DE19512484A1 (de) | 1995-04-04 | 1996-10-17 | Bayer Ag | Kohlenhydratmodifizierte Cytostatika |
| SE9600769D0 (sv) * | 1996-02-28 | 1996-02-28 | Astra Ab | Compounds useful as analgesic |
| US6903075B1 (en) | 1997-05-29 | 2005-06-07 | Merck & Co., Inc. | Heterocyclic amide compounds as cell adhesion inhibitors |
| EP1001764A4 (en) * | 1997-05-29 | 2005-08-24 | Merck & Co Inc | HETEROCYCLIC AMIDE COMPOUNDS AS INHIBITORS OF CELL ADHESION |
| US6703381B1 (en) | 1998-08-14 | 2004-03-09 | Nobex Corporation | Methods for delivery therapeutic compounds across the blood-brain barrier |
| US6306576B1 (en) * | 1999-02-19 | 2001-10-23 | Cleveland Clinic Foundation | Diagnostic methods for asthma |
| US7601739B2 (en) | 2003-08-08 | 2009-10-13 | Virgina Commonwealth University | Compounds having antiestrogenic and tissue selective estrogenic properties, and compounds with anti-androgenic properties for treatment of prostate cancer and androgen receptor dependent diseases |
| WO2006115509A2 (en) | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Small molecule immunopotentiators and assays for their detection |
| US20080045610A1 (en) * | 2004-09-23 | 2008-02-21 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| CA2580694A1 (en) * | 2004-09-23 | 2006-03-30 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| EP3160497A4 (en) * | 2014-06-27 | 2018-01-17 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Conjugates for immunotherapy |
-
1993
- 1993-01-05 SE SE9300012A patent/SE9300012D0/xx unknown
- 1993-12-20 CZ CZ951711A patent/CZ171195A3/cs unknown
- 1993-12-20 SK SK839-95A patent/SK83995A3/sk unknown
- 1993-12-20 CA CA002152380A patent/CA2152380A1/en not_active Abandoned
- 1993-12-20 NZ NZ259597A patent/NZ259597A/en unknown
- 1993-12-20 EP EP94904365A patent/EP0678099A1/en not_active Withdrawn
- 1993-12-20 JP JP6515914A patent/JPH08505386A/ja active Pending
- 1993-12-20 KR KR1019950702750A patent/KR960700269A/ko not_active Withdrawn
- 1993-12-20 WO PCT/SE1993/001090 patent/WO1994015959A1/en not_active Ceased
- 1993-12-20 AU AU58448/94A patent/AU681372B2/en not_active Ceased
- 1993-12-20 PL PL93309778A patent/PL309778A1/xx unknown
- 1993-12-20 HU HU9502041A patent/HUT72597A/hu unknown
- 1993-12-20 FI FI953302A patent/FI953302L/fi unknown
- 1993-12-24 IL IL10816993A patent/IL108169A0/xx unknown
- 1993-12-27 IS IS4115A patent/IS4115A/is unknown
-
1994
- 1994-01-04 MX MX9400255A patent/MX9400255A/es unknown
- 1994-01-04 US US08/176,938 patent/US5602099A/en not_active Expired - Fee Related
- 1994-01-05 ZA ZA9455A patent/ZA9455B/xx unknown
- 1994-01-05 AP APAP/P/1994/000605A patent/AP508A/en active
- 1994-01-05 CN CN94100129A patent/CN1096515A/zh active Pending
- 1994-01-05 SI SI9400005A patent/SI9400005A/sl unknown
- 1994-01-05 YU YU394A patent/YU394A/sh unknown
- 1994-11-03 EE EE9400326A patent/EE9400326A/xx unknown
-
1995
- 1995-06-29 LV LVP-95-197A patent/LV10962B/en unknown
- 1995-07-04 NO NO952650A patent/NO952650L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| LV10962A (lv) | 1995-12-20 |
| JPH08505386A (ja) | 1996-06-11 |
| LV10962B (en) | 1997-04-20 |
| NO952650D0 (no) | 1995-07-04 |
| SK83995A3 (en) | 1996-09-04 |
| IL108169A0 (en) | 1994-04-12 |
| CA2152380A1 (en) | 1994-07-21 |
| CZ171195A3 (en) | 1996-09-11 |
| SI9400005A (en) | 1994-12-31 |
| CN1096515A (zh) | 1994-12-21 |
| KR960700269A (ko) | 1996-01-19 |
| PL309778A1 (en) | 1995-11-13 |
| FI953302A7 (fi) | 1995-07-04 |
| EP0678099A1 (en) | 1995-10-25 |
| EE9400326A (et) | 1996-04-15 |
| WO1994015959A1 (en) | 1994-07-21 |
| AP9400605A0 (en) | 1994-01-31 |
| AU681372B2 (en) | 1997-08-28 |
| FI953302A0 (fi) | 1995-07-04 |
| AP508A (en) | 1996-07-22 |
| FI953302L (fi) | 1995-07-04 |
| HU9502041D0 (en) | 1995-09-28 |
| YU394A (sh) | 1997-07-31 |
| SE9300012D0 (sv) | 1993-01-05 |
| MX9400255A (es) | 1994-07-29 |
| ZA9455B (en) | 1994-07-05 |
| US5602099A (en) | 1997-02-11 |
| IS4115A (is) | 1994-07-06 |
| AU5844894A (en) | 1994-08-15 |
| NZ259597A (en) | 1996-07-26 |
| HUT72597A (en) | 1996-05-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |