NO955305L - Optisk aktive benzotiepinderivater, deres fremstilling og anvendelse - Google Patents

Optisk aktive benzotiepinderivater, deres fremstilling og anvendelse

Info

Publication number
NO955305L
NO955305L NO955305A NO955305A NO955305L NO 955305 L NO955305 L NO 955305L NO 955305 A NO955305 A NO 955305A NO 955305 A NO955305 A NO 955305A NO 955305 L NO955305 L NO 955305L
Authority
NO
Norway
Prior art keywords
preparation
optically active
benzothiazine derivatives
benzothiazine
derivatives
Prior art date
Application number
NO955305A
Other languages
English (en)
Other versions
NO303641B1 (no
NO955305D0 (no
Inventor
Takashi Sohda
Shigehisa Taketomi
Tsuneo Oda
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO955305D0 publication Critical patent/NO955305D0/no
Publication of NO955305L publication Critical patent/NO955305L/no
Publication of NO303641B1 publication Critical patent/NO303641B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655363Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring
    • C07F9/655372Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/67Phosphorus compounds having sulfur as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6571Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
    • C07F9/657163Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
    • C07F9/657181Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO955305A 1994-12-28 1995-12-27 Optisk aktive benzotiepinderivater, mellomprodukter for deres fremstilling og deres anvendelse NO303641B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP32727594 1994-12-28

Publications (3)

Publication Number Publication Date
NO955305D0 NO955305D0 (no) 1995-12-27
NO955305L true NO955305L (no) 1996-07-01
NO303641B1 NO303641B1 (no) 1998-08-10

Family

ID=18197308

Family Applications (1)

Application Number Title Priority Date Filing Date
NO955305A NO303641B1 (no) 1994-12-28 1995-12-27 Optisk aktive benzotiepinderivater, mellomprodukter for deres fremstilling og deres anvendelse

Country Status (20)

Country Link
US (2) US6346521B1 (no)
EP (1) EP0719782B1 (no)
KR (1) KR960022542A (no)
CN (1) CN1058718C (no)
AR (1) AR002018A1 (no)
AT (1) ATE202782T1 (no)
AU (1) AU689004B2 (no)
BR (1) BR9506098A (no)
CA (1) CA2166152A1 (no)
DE (1) DE69521595T2 (no)
DK (1) DK0719782T3 (no)
ES (1) ES2158034T3 (no)
FI (1) FI956273L (no)
GR (1) GR3036757T3 (no)
HU (1) HUT74562A (no)
NO (1) NO303641B1 (no)
NZ (1) NZ280745A (no)
PT (1) PT719782E (no)
RU (1) RU2162083C2 (no)
TW (1) TW403757B (no)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR003001A1 (es) * 1995-06-05 1998-05-27 Takeda Chemical Industries Ltd Composicion farmaceutica estimuladora de la osteogenesis.
US5910492A (en) * 1995-06-05 1999-06-08 Takeda Chemical Industries, Ltd. Osteogenic promoting pharmaceutical composition
EP0842179A1 (en) * 1995-07-24 1998-05-20 Takeda Chemical Industries, Ltd. Production of optically active benzothiepin salts
EP0949927B1 (en) 1996-08-26 2002-10-16 Takeda Chemical Industries, Ltd. Pharmaceutical composition containing osteogenesis-promoting substance and a polyethylene glycol
WO1998015263A2 (en) * 1996-10-09 1998-04-16 Takeda Chemical Industries, Ltd. A method for producing a microparticle
EP1087774A2 (en) * 1998-06-15 2001-04-04 Takeda Chemical Industries, Ltd. Compositions for treating cartilage disease comprising certain sulfur-containing heterocyclic compounds
AU5194999A (en) 1998-08-07 2000-02-28 Takeda Chemical Industries Ltd. Benzothiepin derivatives, process for the preparation of the same and uses thereof
AR020158A1 (es) * 1998-08-12 2002-04-10 Takeda Chemical Industries Ltd Mejorador del factor de induccion para la diferenciacion celular
KR20010075476A (ko) * 1998-09-30 2001-08-09 다케다 야쿠힌 고교 가부시키가이샤 골 복구 물질/인공 골 조성물
EP1286984A2 (en) * 2000-03-10 2003-03-05 Pharmacia Corporation Method for the preparation of tetrahydrobenzothiepines
WO2003007916A1 (en) * 2001-07-17 2003-01-30 Teva Pharmaceutical Industries Ltd. Dosage forms for immediate gastric release of a calcium transport stimulator coupled with delayed gastric release of a bis-phosphonate
US20050026871A1 (en) * 2002-07-17 2005-02-03 Moshe Flashner-Barak Method of increasing bioavailability of alendronate or other bis-phosphonate by predose administration of vitamin D derivative
EP1640010A1 (en) * 2003-07-01 2006-03-29 Astellas Pharma Inc. Agent inducing increase in bone mass
KR20100076939A (ko) * 2007-06-29 2010-07-06 케이씨아이 라이센싱 인코포레이티드 뼈 및 연골 형성의 활성화
EP2380878B1 (en) 2009-01-19 2013-08-14 Daiichi Sankyo Company, Limited Cyclic compound having hetero atom
CA2758144C (en) 2009-04-06 2014-05-13 Daiichi Sankyo Company, Limited Cyclic compound having substituted phenyl group
CA2791020A1 (en) 2010-04-28 2011-11-03 Daiichi Sankyo Company, Limited [5,6] heterocyclic compound
PL3040329T3 (pl) 2013-08-29 2019-04-30 Kyoto Pharma Ind Związek aromatyczny i jego zastosowanie w leczeniu chorób związanych z metabolizmem kości

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0138535A3 (en) * 1983-10-13 1987-01-28 British Telecommunications Plc Visual display logic simulation system
US5158943A (en) * 1988-11-21 1992-10-27 Takeda Chemical Industries, Ltd. Sulfur-containing heterocyclic compounds
NZ231939A (en) * 1988-12-28 1991-07-26 Takeda Chemical Industries Ltd Benzothiopyran derivatives and medicaments
ES2157887T3 (es) * 1990-05-30 2001-09-01 Takeda Chemical Industries Ltd Compuestos heterociclicos que contienen azufre.
JP3165866B2 (ja) * 1990-06-06 2001-05-14 武田薬品工業株式会社 含硫黄複素環化合物

Also Published As

Publication number Publication date
EP0719782A1 (en) 1996-07-03
AU4069395A (en) 1996-07-04
ATE202782T1 (de) 2001-07-15
EP0719782B1 (en) 2001-07-04
CN1058718C (zh) 2000-11-22
ES2158034T3 (es) 2001-09-01
RU2162083C2 (ru) 2001-01-20
KR960022542A (ko) 1996-07-18
TW403757B (en) 2000-09-01
DK0719782T3 (da) 2001-09-24
NO303641B1 (no) 1998-08-10
FI956273A7 (fi) 1996-06-29
BR9506098A (pt) 1997-12-23
FI956273A0 (fi) 1995-12-27
DE69521595T2 (de) 2002-05-23
US6632807B1 (en) 2003-10-14
CN1131669A (zh) 1996-09-25
NZ280745A (en) 1997-09-22
US6346521B1 (en) 2002-02-12
HUT74562A (en) 1997-01-28
FI956273L (fi) 1996-06-29
PT719782E (pt) 2001-10-31
CA2166152A1 (en) 1996-06-29
GR3036757T3 (en) 2001-12-31
HU9503802D0 (en) 1996-02-28
AU689004B2 (en) 1998-03-19
AR002018A1 (es) 1998-01-07
DE69521595D1 (de) 2001-08-09
NO955305D0 (no) 1995-12-27

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Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN JUNE 2003