NO960148D0 - Anvendelse av kumariner og karbostyriler som PLA2-inhibitorer, nye kumariner og karbostyriler, fremgangsmåte for fremstilling samt legemiddel inneholdende slike - Google Patents

Anvendelse av kumariner og karbostyriler som PLA2-inhibitorer, nye kumariner og karbostyriler, fremgangsmåte for fremstilling samt legemiddel inneholdende slike

Info

Publication number
NO960148D0
NO960148D0 NO960148A NO960148A NO960148D0 NO 960148 D0 NO960148 D0 NO 960148D0 NO 960148 A NO960148 A NO 960148A NO 960148 A NO960148 A NO 960148A NO 960148 D0 NO960148 D0 NO 960148D0
Authority
NO
Norway
Prior art keywords
carbostyrils
coumarins
pct
preparation
drug containing
Prior art date
Application number
NO960148A
Other languages
English (en)
Other versions
NO960148L (no
Inventor
Walter-Gunar Friebe
Wolfgang Schaefer
Werner Scheuer
Ulrich Tibes
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of NO960148D0 publication Critical patent/NO960148D0/no
Publication of NO960148L publication Critical patent/NO960148L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/366Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37Coumarins, e.g. psoralen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/06Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
    • C07D311/08Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
    • C07D311/18Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted otherwise than in position 3 or 7
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nutrition Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO960148A 1993-07-13 1996-01-12 Anvendelse av kumariner og karbostyriler som PLA2-inhibitorer, nye kumariner og karbostyriler, fremgangsmåte for fremstilling samt legemiddel inneholdende slike NO960148L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4323409A DE4323409A1 (de) 1993-07-13 1993-07-13 Verwendung von Cumarinen und Carbostyrilen als PLA¶2¶-Inhibitoren, neue Cumarine und Carbostyrile, Verfahren zu ihrer Herstellung und Arzneimittel
PCT/EP1994/002251 WO1995002588A1 (de) 1993-07-13 1994-07-09 Verwendung von cumarinen und carbostyrilen als pla2-inhibitoren, neue cumarine und carbostyrile, verfahren zu ihrer herstellung und arzneimittel

Publications (2)

Publication Number Publication Date
NO960148D0 true NO960148D0 (no) 1996-01-12
NO960148L NO960148L (no) 1996-03-12

Family

ID=6492685

Family Applications (1)

Application Number Title Priority Date Filing Date
NO960148A NO960148L (no) 1993-07-13 1996-01-12 Anvendelse av kumariner og karbostyriler som PLA2-inhibitorer, nye kumariner og karbostyriler, fremgangsmåte for fremstilling samt legemiddel inneholdende slike

Country Status (16)

Country Link
US (1) US5716983A (no)
EP (1) EP0708766B1 (no)
JP (1) JPH08512057A (no)
KR (1) KR960703887A (no)
CN (1) CN1130381A (no)
AT (1) ATE161010T1 (no)
AU (1) AU686197B2 (no)
CA (1) CA2167071A1 (no)
CZ (1) CZ6896A3 (no)
DE (2) DE4323409A1 (no)
FI (1) FI960149A7 (no)
HU (1) HUT73764A (no)
NO (1) NO960148L (no)
NZ (1) NZ268608A (no)
RU (1) RU2133745C1 (no)
WO (1) WO1995002588A1 (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2301586A1 (en) * 1997-08-28 1999-03-04 William Louis Macias Method for treatment of non-rheumatoid arthritis
BR9910095A (pt) 1998-05-01 2000-12-26 Lilly Co Eli Compostos inibidores de spla2 para tratamento de doença
EP1140889B1 (en) * 1998-12-30 2003-08-27 Signal Pharmaceuticals, Inc. Compounds and methods for modulation of estrogen receptors
US6291456B1 (en) * 1998-12-30 2001-09-18 Signal Pharmaceuticals, Inc. Compounds and methods for modulation of estrogen receptors
US6331562B1 (en) 1998-12-30 2001-12-18 Signal Pharmaceuticals, Inc. Compounds and methods for modulation of estrogen receptors
GB9920912D0 (en) * 1999-09-03 1999-11-10 Indena Spa Novel derivatives of flavones,xanthones and coumarins
US7027092B2 (en) * 2001-09-17 2006-04-11 Hewlett-Packard Development Company, L.P. Image capture and storage device
CN1315836C (zh) 2002-04-26 2007-05-16 奥索-麦克尼尔药品公司 用作雄激素受体调节剂的2-(喹诺酮基)-稠合杂环
KR20040001144A (ko) * 2002-06-27 2004-01-07 김대경 신규한 적혈구 세포질형 포스포리파아제 에이 투 효소,그에 대한 항체, 이들의 용도 및 제조 방법
US7538233B2 (en) * 2003-09-05 2009-05-26 Aventis Pharmaceuticals Inc. Coumarins as iNOS inhibitors
DE102004032440B4 (de) * 2004-07-05 2007-02-08 Bioplanta Arzneimittel Gmbh Verwendung von trisubstituierten Benzopyranonen
CN102532015B (zh) * 2012-01-18 2013-10-23 云南大学 香豆素及其类似物的固相合成方法
CN105687184A (zh) * 2016-04-06 2016-06-22 梁海月 蛇床子素在制备治疗溃疡性结肠炎的药物方面的应用
CN111423450B (zh) * 2020-04-29 2021-10-26 上海天马有机发光显示技术有限公司 化合物、显示面板以及显示装置

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU175622A (no) *
FR2035M (fr) * 1962-06-29 1963-09-23 Dausse Lab Médicament a base de dérivé du méthyl-4 esculétol.
BE734121A (no) * 1968-06-14 1969-11-17
GB1432809A (en) * 1973-04-19 1976-04-22 Beecham Group Ltd Coumarin derivatives
FR2276819A1 (fr) * 1974-07-05 1976-01-30 Fabre Sa Pierre Facteurs p lipophile a action anti-inflammatoire locale utilisables dans le traitement de syndromes dermatologiques
US4136192A (en) * 1975-09-23 1979-01-23 Beecham Group Limited 4-hydroxy-3-nitro (cyano) coumarins
US4210667A (en) * 1979-04-19 1980-07-01 Pfizer Inc. Pharmaceutical preparations containing coumarin carboxylic acid derivatives
JPS6056985A (ja) * 1983-09-08 1985-04-02 Sankyo Co Ltd クマリン誘導体
DE3568773D1 (en) * 1984-05-24 1989-04-20 Ciba Geigy Ag Resorcin ethers
IT1196133B (it) * 1984-06-06 1988-11-10 Ausonia Farma Srl Derivati furanici con attivita' antiulcera
DE3427985A1 (de) * 1984-07-28 1986-01-30 Boehringer Mannheim Gmbh, 6800 Mannheim Neue 2h-l-benzopyran-2-on-derivate, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten
US5124334A (en) * 1987-11-30 1992-06-23 Du Pont Merck Pharmaceutical Company Benzylalcohol phospholipase A2 inhibitors
FR2677023B1 (fr) * 1991-05-30 1994-02-25 Eurobio Laboratoires Derives de coumarine hydrosolubles, leur preparation et leur utilisation comme substrat d'enzyme.
JPH06312925A (ja) * 1993-03-02 1994-11-08 Kureha Chem Ind Co Ltd 軟骨保護剤及び新規エスクレチン誘導体
CA2133115A1 (en) * 1993-10-01 1995-04-02 Yozo Hori Carboxylate derivatives exhibiting phospholipase a2 inhibitory activity

Also Published As

Publication number Publication date
JPH08512057A (ja) 1996-12-17
NZ268608A (en) 1997-09-22
US5716983A (en) 1998-02-10
FI960149A0 (fi) 1996-01-12
HUT73764A (en) 1996-09-30
CZ6896A3 (en) 1996-04-17
DE4323409A1 (de) 1995-01-19
FI960149L (fi) 1996-01-12
NO960148L (no) 1996-03-12
DE59404786D1 (de) 1998-01-22
AU686197B2 (en) 1998-02-05
EP0708766B1 (de) 1997-12-10
WO1995002588A1 (de) 1995-01-26
ATE161010T1 (de) 1997-12-15
CA2167071A1 (en) 1995-01-26
CN1130381A (zh) 1996-09-04
EP0708766A1 (de) 1996-05-01
HU9503973D0 (en) 1996-03-28
RU2133745C1 (ru) 1999-07-27
KR960703887A (ko) 1996-08-31
AU7188094A (en) 1995-02-13
FI960149A7 (fi) 1996-01-12

Similar Documents

Publication Publication Date Title
NO960148D0 (no) Anvendelse av kumariner og karbostyriler som PLA2-inhibitorer, nye kumariner og karbostyriler, fremgangsmåte for fremstilling samt legemiddel inneholdende slike
DK41193D0 (da) Ionkanalaabnere
DZ1794A1 (fr) Nouvelle formule pharmaceutique.
NO914356L (no) Mono n-substituerte 1,4,7,10-tetraazacyklododekanderivater, fremgangsmaater for fremstilling av dem og farmasoeytiskemidler som inneholder dem
BR9408246A (pt) Composto derivado de 3-azabicicloalcano N-substituído
PL314188A1 (en) Novel derivatives of benzoguanidine, method of obtaining them and their application in pharmaceutical compositions
DE122005000055I1 (de) Kristallines ceftiofur (freie S{ure)
NO955352L (no) Metylfosforsyreester, fremgangsmåte for fremstilling samt anvendelse
GEP20033028B (en) Heterocyclic Compounds as Inhibitors of Rotamase Enzymes, Method for Their Production, Pharmaceutical Composition Containing Them and Use Thereof
DE69332259D1 (de) Kondensierte Thiadiazolderivate, Verfahren zu ihrer Herstellung und deren Verwendung
ATE148108T1 (de) Beta,beta-dimethyl-4-piperidinethanamin-derivat als inhibitoren der cholesterin-biosynthese
ATE170530T1 (de) Thiazolidinderivate, ihre herstellung und medikamente, die sie enthalten
NO306400B1 (no) N-substituerte azabicykloheptan-derivater, anvendelse derav og farmasöytisk preparat
ATE120369T1 (de) Verwendung stabiler oxapenem-3-carbonsäuren zur herstellung beta-lactamase hemmender arzneimittel.
PT99280A (pt) Processo de preparacao de derivados do indolo e de composicoes farmaceuticas
DE59409923D1 (de) Substituierte aminoalkylaminopyridine
KR960700223A (ko) C-치환 디에틸렌 트리아민의 제조 방법(Process for the Production of C-Substituted Diethylenetriamines)
ATE144986T1 (de) Aminoacylderivate von gem- diphosphonsauren,verfahren zu deren herstellung und pharmazeutische zubereitungen,die sie enthalten
ATE145647T1 (de) Gem-diphosphonsäure-nitrosocarbamoylderivate, verfahren zu deren herstellung und sie enthaltende pharmazeutische zubereitungen
AU5699894A (en) Use of benzotriazines as pla2 inhibitors, and new benzotriazines
EE03488B1 (et) Meetod anhüdroekgoniini estrite valmistamiseks
NO961657D0 (no) Dibenz[b,eÅoksepinderivater, fremgangsmåte for fremstilling samt legemiddel inneholdende slike

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application