NO960177L - Fremgangsmåte for fremstilling av sakaridsammensetninger - Google Patents

Fremgangsmåte for fremstilling av sakaridsammensetninger

Info

Publication number
NO960177L
NO960177L NO960177A NO960177A NO960177L NO 960177 L NO960177 L NO 960177L NO 960177 A NO960177 A NO 960177A NO 960177 A NO960177 A NO 960177A NO 960177 L NO960177 L NO 960177L
Authority
NO
Norway
Prior art keywords
saccharide compositions
acceptor moiety
preparing
saccharide
preparing saccharide
Prior art date
Application number
NO960177A
Other languages
English (en)
Other versions
NO960177D0 (no
Inventor
Stephen Roth
Original Assignee
Neose Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neose Pharm Inc filed Critical Neose Pharm Inc
Publication of NO960177D0 publication Critical patent/NO960177D0/no
Publication of NO960177L publication Critical patent/NO960177L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1051—Hexosyltransferases (2.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

En fremgangsmåte for fremstilling av sakaridsammensetninger er beskrevet, l denne fremgangsmåten blir en akseptordel kontaktet med minst et donorsakarid i nærvær av minst en celleoverflate-bundet glykosyltransferase spesifikk for katalysering av koblingen av akseptordelen med donorsakaridet. Akseptordelen som blir anvendt er et karbohydrat, et protein, et glykoprotein, et lipid eller et glykolipid.
NO960177A 1993-07-15 1996-01-15 Fremgangsmåte for fremstilling av sakaridsammensetninger NO960177L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9137293A 1993-07-15 1993-07-15
PCT/US1994/007807 WO1995002683A1 (en) 1993-07-15 1994-07-15 Method of synthesizing saccharide compositions

Publications (2)

Publication Number Publication Date
NO960177D0 NO960177D0 (no) 1996-01-15
NO960177L true NO960177L (no) 1996-03-07

Family

ID=22227422

Family Applications (1)

Application Number Title Priority Date Filing Date
NO960177A NO960177L (no) 1993-07-15 1996-01-15 Fremgangsmåte for fremstilling av sakaridsammensetninger

Country Status (9)

Country Link
US (2) US5879912A (no)
EP (1) EP0785988A1 (no)
JP (1) JPH09503905A (no)
CN (1) CN1129953A (no)
AU (1) AU691510B2 (no)
CA (1) CA2167157A1 (no)
FI (1) FI960173L (no)
NO (1) NO960177L (no)
WO (1) WO1995002683A1 (no)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2237586A1 (en) * 1996-09-13 1998-03-19 Kyowa Hakko Kogyo Co., Ltd. Processes for producing sugar nucleotides and complex carbohydrates
WO1998012343A1 (en) * 1996-09-17 1998-03-26 Kyowa Hakko Kogyo Co., Ltd. Processes for producing sugar nucleotides and complex carbohydrates
JP2001502005A (ja) 1996-10-10 2001-02-13 サイテル コーポレイション 限外濾過、逆浸透及びナノ濾過を利用する炭水化物の精製
US5945314A (en) * 1997-03-31 1999-08-31 Abbott Laboratories Process for synthesizing oligosaccharides
US6045854A (en) * 1997-03-31 2000-04-04 Abbott Laboraties Nutritional formulations containing oligosaccharides
DE19716731A1 (de) * 1997-04-14 1998-10-15 Biopract Gmbh Verfahren zur enzymatischen Herstellung von Fructosylverbindungen
US7060469B2 (en) * 1998-04-02 2006-06-13 The Board Of Regents Of The University Of Oklahoma Polymer grafting by polysaccharide synthases
US6444447B1 (en) * 1998-11-11 2002-09-03 The Board Of Regents Of The University Of Oklahoma Polymer grafting by polysaccharide synthases
US20060105431A1 (en) * 1998-11-11 2006-05-18 Deangelis Paul L Polymer grafting by polysaccharide synthases using artificial sugar acceptors
PT1137789E (pt) 1998-12-09 2010-10-21 Phyton Holdings Llc Um método para produzir glicoproteínas possuindo glicosilação de tipo humano
US6699705B2 (en) * 1999-02-01 2004-03-02 National Research Council Of Canada Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics
US20010051349A1 (en) 2000-02-17 2001-12-13 Glycominds Ltd. Combinatorial complex carbohydrate libraries and methods for the manufacture and uses thereof
EP1189643A1 (en) * 1999-06-30 2002-03-27 Novartis AG Ophthalmic molding
FR2796082B1 (fr) 1999-07-07 2003-06-27 Centre Nat Rech Scient Procede de production d'oligosaccharides
ATE365219T1 (de) 1999-10-26 2007-07-15 Plant Res Int Bv Glykolisierung des säugetiertyps in pflanzen
US7534589B2 (en) * 1999-11-10 2009-05-19 The Board Of Regents Of The University Of Oklahoma Polymer grafting by polysaccharide synthases
US20020132320A1 (en) * 2001-01-10 2002-09-19 Wang Peng George Glycoconjugate synthesis using a pathway-engineered organism
CN100385006C (zh) 2001-01-19 2008-04-30 陶氏化学公司 利用植物细胞分泌性生产具有人型糖链的糖蛋白的方法
CN1541059A (zh) * 2001-03-06 2004-10-27 �Ϻ���ͨ��ѧ 具有动物型糖链加成功能的植物细胞
JP2005527467A (ja) 2001-08-29 2005-09-15 ネオーズ テクノロジーズ， インコーポレイテッド 新規な合成ガングリオシド誘導体およびその組成物
EP1438387A4 (en) * 2001-09-14 2004-10-13 Momenta Pharmaceuticals Inc METHODS OF MAKING GLYCOMOLECULES WITH IMPROVED ACTIVITY, AND USES THEREOF
US20040214228A9 (en) * 2001-09-14 2004-10-28 Ganesh Venkataraman Methods of evaluating glycomolecules for enhanced activities
EP2292273A3 (en) * 2001-10-10 2011-11-23 BioGeneriX AG Remodeling and glycoconjugation of peptides
US7173003B2 (en) 2001-10-10 2007-02-06 Neose Technologies, Inc. Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF
US7214660B2 (en) 2001-10-10 2007-05-08 Neose Technologies, Inc. Erythropoietin: remodeling and glycoconjugation of erythropoietin
KR100527437B1 (ko) * 2001-11-20 2005-11-09 한국생명공학연구원 β-1,4-갈락토실트랜스퍼라제의 생산방법
US20030166866A1 (en) * 2002-01-28 2003-09-04 Land O' Lakes, Inc. Method of processing a proteinaceous material to recover K-casein macropeptide and polymers of a-lactalbumin and B-lactoglobulin
JP4048289B2 (ja) * 2002-02-26 2008-02-20 独立行政法人科学技術振興機構 微細自己集合体
JP4052553B2 (ja) * 2002-03-07 2008-02-27 独立行政法人科学技術振興機構 微細自己集合体の製法
CA2478294C (en) 2002-03-19 2013-09-03 Plant Research International B.V. Gntiii (udp-n-acetylglucosamine:beta-d mannoside beta (1,4)-n-acetylglucosaminyltransferase iii) expression in plants
CA2923247A1 (en) 2002-03-19 2003-09-25 Stichting Dienst Landbouwkundig Onderzoek Optimizing glycan processing in plants
AR042145A1 (es) 2002-11-27 2005-06-08 Dow Agrociences Llc Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
WO2004066808A2 (en) * 2002-12-20 2004-08-12 Momenta Pharmaceuticals, Inc. Glycan markers for diagnosing and monitoring disease
JP4405736B2 (ja) 2003-01-31 2010-01-27 コニカミノルタホールディングス株式会社 データベースシステム
JP2004261885A (ja) * 2003-02-18 2004-09-24 Japan Science & Technology Agency 有機ナノチューブへ機能性物質を導入する方法
CA2518171C (en) 2003-03-06 2013-07-09 Neose Technologies, Inc. Methods and compositions for the enzymatic synthesis of gangliosides
CA2522345A1 (en) 2003-04-09 2004-11-18 Neose Technologies, Inc. Glycopegylation methods and proteins/peptides produced by the methods
WO2005012484A2 (en) 2003-07-25 2005-02-10 Neose Technologies, Inc. Antibody-toxin conjugates
US20080305992A1 (en) 2003-11-24 2008-12-11 Neose Technologies, Inc. Glycopegylated erythropoietin
WO2006010143A2 (en) 2004-07-13 2006-01-26 Neose Technologies, Inc. Branched peg remodeling and glycosylation of glucagon-like peptide-1 [glp-1]
EP1814573B1 (en) 2004-10-29 2016-03-09 ratiopharm GmbH Remodeling and glycopegylation of fibroblast growth factor (fgf)
CA2593682C (en) 2005-01-10 2016-03-22 Neose Technologies, Inc. Glycopegylated granulocyte colony stimulating factor
US9187546B2 (en) 2005-04-08 2015-11-17 Novo Nordisk A/S Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en) 2005-10-26 2007-05-10 Neose Technologies, Inc. One pot desialylation and glycopegylation of therapeutic peptides
US20090048440A1 (en) 2005-11-03 2009-02-19 Neose Technologies, Inc. Nucleotide Sugar Purification Using Membranes
JP2006143723A (ja) * 2005-11-16 2006-06-08 Japan Science & Technology Agency 微細自己集合体
CN101516388B (zh) 2006-07-21 2012-10-31 诺和诺德公司 通过o-联糖基化序列的肽的糖基化
US8969532B2 (en) 2006-10-03 2015-03-03 Novo Nordisk A/S Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
EP2144923B1 (en) 2007-04-03 2013-02-13 BioGeneriX AG Methods of treatment using glycopegylated g-csf
AU2008240080A1 (en) * 2007-04-16 2008-10-23 Momenta Pharmaceuticals, Inc. Defined glycoprotein products and related methods
KR101426667B1 (ko) 2007-04-17 2014-08-06 스티칭 디엔스트 랜드보위쿤디그 온데조에크 비-포유동물 글리코실트랜스퍼라제의 발현에 의한 식물에서의 포유동물형 글리코실화
WO2008154639A2 (en) 2007-06-12 2008-12-18 Neose Technologies, Inc. Improved process for the production of nucleotide sugars
WO2010111530A1 (en) 2009-03-25 2010-09-30 Seneb Biosciences, Inc. Glycolipids as treatment for disease
AU2011237442A1 (en) 2010-04-07 2012-10-18 Momenta Pharmaceuticals, Inc. High mannose glycans
CN105671108A (zh) 2010-06-02 2016-06-15 沃维公司 甜菊糖苷的重组生产
WO2012125553A2 (en) 2011-03-12 2012-09-20 Momenta Pharmaceuticals, Inc. N-acetylhexosamine-containing n-glycans in glycoprotein products
DK2722394T3 (en) 2011-06-07 2018-06-18 Hero Ag OBJECTIVES OF OLIGOSACCHARIDES BY A BIOTECHNOLOGICAL PROCEDURE
EP2742142B2 (en) 2011-08-08 2020-03-25 Evolva SA Recombinant production of steviol glycosides
US9695244B2 (en) 2012-06-01 2017-07-04 Momenta Pharmaceuticals, Inc. Methods related to denosumab
WO2014018747A2 (en) 2012-07-26 2014-01-30 Momenta Pharmaceuticals, Inc. Glycoproteins with anti-inflammatory properties
CA2899276C (en) 2013-02-06 2022-11-01 Evolva Sa Methods for improved production of rebaudioside d and rebaudioside m
US10017804B2 (en) 2013-02-11 2018-07-10 Evolva Sa Efficient production of steviol glycosides in recombinant hosts
US10450361B2 (en) 2013-03-15 2019-10-22 Momenta Pharmaceuticals, Inc. Methods related to CTLA4-Fc fusion proteins
ES2708759T3 (es) 2013-05-13 2019-04-11 Momenta Pharmaceuticals Inc Procedimientos para el tratamiento de la neurodegeneración
EP3058084A4 (en) 2013-10-16 2017-07-05 Momenta Pharmaceuticals, Inc. Sialylated glycoproteins
MX2017001859A (es) 2014-08-11 2017-04-11 Evolva Sa Produccion de glicosidos de esteviol en hospederos recombinantes.
JP2017528134A (ja) 2014-09-09 2017-09-28 エヴォルヴァ エスアー．Ｅｖｏｌｖａ Ｓａ． 組み換え宿主におけるステビオールグリコシドの生産
US9616114B1 (en) 2014-09-18 2017-04-11 David Gordon Bermudes Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity
BR112017016338A2 (en) 2015-01-30 2018-03-27 Evolva Sa production of steviol glycosides in recombinant hosts
CA3255837A1 (en) 2015-03-16 2025-10-30 Dsm Ip Assets B.V. Udp-glycosyltransferases
US10676723B2 (en) 2015-05-11 2020-06-09 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
JP2018522569A (ja) 2015-08-07 2018-08-16 エヴォルヴァ エスアー．Ｅｖｏｌｖａ Ｓａ． 組換え宿主内でのステビオールグリコシドの産生
MY198001A (en) 2016-04-13 2023-07-25 Evolva SA Production of steviol glycoside in recombinant hosts
US11312741B2 (en) 2016-04-19 2022-04-26 Glycom A/S Separation of oligosaccharides from fermentation broth
WO2017198682A1 (en) 2016-05-16 2017-11-23 Evolva Sa Production of steviol glycosides in recombinant hosts
US11396669B2 (en) 2016-11-07 2022-07-26 Evolva Sa Production of steviol glycosides in recombinant hosts
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
US11180535B1 (en) 2016-12-07 2021-11-23 David Gordon Bermudes Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58149697A (ja) * 1982-02-27 1983-09-06 Dainippon Ink & Chem Inc β−１，３グリコシルステビオシドの製造方法
US5135854A (en) * 1987-10-29 1992-08-04 Zymogenetics, Inc. Methods of regulating protein glycosylation
FR2626583B1 (fr) * 1988-01-29 1991-03-15 Bioeurope Procede de preparation enzymatique d'oligodextranes utiles dans la fabrication de substituts du sucre, et nouveaux oligodextranes
US5047335A (en) * 1988-12-21 1991-09-10 The Regents Of The University Of Calif. Process for controlling intracellular glycosylation of proteins
FR2640997A1 (en) * 1988-12-22 1990-06-29 Ajinomoto Kk Process for the manufacture of a galactose transfer product.
US5032519A (en) * 1989-10-24 1991-07-16 The Regents Of The Univ. Of California Method for producing secretable glycosyltransferases and other Golgi processing enzymes
US5324663A (en) * 1990-02-14 1994-06-28 The Regents Of The University Of Michigan Methods and products for the synthesis of oligosaccharide structures on glycoproteins, glycolipids, or as free molecules, and for the isolation of cloned genetic sequences that determine these structures
WO1991016449A1 (en) * 1990-04-16 1991-10-31 The Trustees Of The University Of Pennsylvania Saccharide compositions, methods and apparatus for their synthesis
US5348867A (en) * 1991-11-15 1994-09-20 George Georgiou Expression of proteins on bacterial surface
US5545553A (en) * 1994-09-26 1996-08-13 The Rockefeller University Glycosyltransferases for biosynthesis of oligosaccharides, and genes encoding them

Also Published As

Publication number Publication date
NO960177D0 (no) 1996-01-15
US5879912A (en) 1999-03-09
AU691510B2 (en) 1998-05-21
FI960173A7 (fi) 1996-03-15
EP0785988A1 (en) 1997-07-30
AU7329994A (en) 1995-02-13
JPH09503905A (ja) 1997-04-22
WO1995002683A1 (en) 1995-01-26
FI960173A0 (fi) 1996-01-15
EP0785988A4 (no) 1997-07-30
US6284493B1 (en) 2001-09-04
CN1129953A (zh) 1996-08-28
FI960173L (fi) 1996-03-15
CA2167157A1 (en) 1995-01-26

Similar Documents

Publication Publication Date Title
Race et al. An α-d-galactosyltransferase associated with the blood-group B character
FI942916A0 (fi) Menetelmä glykosyylitransferaasien saamiseksi
SE8801080D0 (sv) Sett att syntetisera oligosackarider
BR8907597A (pt) Processo para obtencao de compostos de alquilglicosideo a partir de oligo-e/ou polissacaridios
DE3585274D1 (de) Geophonfeder.
PT81689A (en) Process for the preparation of homodisaccharide hypoglycemic agents namely glycosides of 2,6-imino-2,6-dideoxy-d-glycero-l-gulo-heptitol (homonojirimycin)
Robbins et al. Effects of UDP-glucose addition on the synthesis of mannosyl lipid-linked oligosaccharides by cell-free fibroblast preparations.
AU2445488A (en) Injection systems for sample testing for luminometers
JPS5655361A (en) Chromogen compound
Basu et al. Biosynthesis in vitro of Ii core glycosphingolipids from neolactotetraosylceramide by beta 1-3-and beta 1-6-N-acetylglucosaminyltransferases from mouse T-lymphoma.
GROSS Fluorescent CMP‐sialic acids as a tool to study the specificity of the CMP‐sialic acid carrier and the glycoconjugate sialylation in permeabilized cells
SE8902767L (sv) Kemiskt foerfarande
IT8224870A0 (it) Miglioramento in e relativo a un enzima per decomposizione di uncarbo-idrato ad alto peso molecolare, il carboidrato isolato ad alto peso molecolare, un metodo per la selezione di un microorganismo produttore di tale enzima e un metodo per laproduzione di tale enzima.
Angata et al. Identification, characterization, and developmental expression of a novel α2→ 8-KDN-transferase which terminates elongation of α2→ 8-linked oligo-polysialic acid chain synthesis in trout egg polysialoglycoproteins
EP0251195A3 (en) Method and reagent for the determination of alpha-amylase
EP0301522A3 (en) Process for producton of isomaltulose
Mühlradt Biosynthesis of Salmonella lipopolysaccharide. The in vitro transfer of phosphate to the heptose moiety of the core
CA2241782A1 (en) Cross-linked polypeptide fragments of .beta.-galactosidase
PT83446B (pt) Processo de preparacao de um complexo antibiotico aad-609
ES2027736T3 (es) Procedimiento para eliminar enturbiamientos inespecificos.
ES506116A0 (es) Procedimiento para la obtencion de isomaltulosa a partir de sacarosa
PT93300A (pt) Processo para a sintese de proteinas utilizando vectores de expressao na levedura de cisao schizosaccharomyces pombe
EP0387875A3 (en) Method for determination of activities of glycosyltransferases and its use
Wittner et al. Studies of Streptococcal Cell Walls VII. Carbohydrate Composition of Group B Cell Walls
Katzman et al. Physical and chemical studies on glycoproteins: II. Isolation and characterization of oligosaccharides from porcine submaxillary glycoproteins

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application