NO960251L - Vitamin D-analoger - Google Patents

Vitamin D-analoger

Info

Publication number: NO960251L
Authority: NO; Norway
Prior art keywords: alpha; vitamin; azide; optionally substituted; group
Prior art date: 1993-07-23

Application number

NO960251A

Other languages

English (en)

Other versions

NO314453B1 (no

NO960251D0 (no

Inventor

Robert Henry Hesse

Malathi Ramgopal

Gaddam Subba Reddy

Sundara Katugam Srinivas Setty

Original Assignee

Res Inst Medicine Chem

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-07-23

Filing date

1996-01-22

Publication date

1996-03-22

1996-01-22 Application filed by Res Inst Medicine Chem filed Critical Res Inst Medicine Chem

1996-01-22 Publication of NO960251D0 publication Critical patent/NO960251D0/no

1996-03-22 Publication of NO960251L publication Critical patent/NO960251L/no

2003-03-24 Publication of NO314453B1 publication Critical patent/NO314453B1/no

Links

229930003316 Vitamin D Natural products 0.000 title abstract 2
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title abstract 2
235000019166 vitamin D Nutrition 0.000 title abstract 2
239000011710 vitamin D Substances 0.000 title abstract 2
150000003710 vitamin D derivatives Chemical class 0.000 title abstract 2
229940046008 vitamin d Drugs 0.000 title abstract 2
150000001540 azides Chemical class 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
125000001399 1,2,3-triazolyl group Chemical group N1N=NC(=C1)* 0.000 abstract 1
OFHCOWSQAMBJIW-AVJTYSNKSA-N alfacalcidol Chemical class C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C OFHCOWSQAMBJIW-AVJTYSNKSA-N 0.000 abstract 1
125000002947 alkylene group Chemical group 0.000 abstract 1
230000000125 calcaemic effect Effects 0.000 abstract 1
-1 cyclohexylidene moiety Chemical group 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000001747 exhibiting effect Effects 0.000 abstract 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
125000001425 triazolyl group Chemical group 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Immunology (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Hematology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Transplantation (AREA)
Oncology (AREA)
Rheumatology (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Saccharide Compounds (AREA)

NO19960251A 1993-07-23 1996-01-22 Vitamin D-analoger NO314453B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB939315253A GB9315253D0 (en)	1993-07-23	1993-07-23	Chemical compounds
PCT/GB1994/001587 WO1995003273A1 (en)	1993-07-23	1994-07-22	Vitamin d analogues

Publications (3)

Publication Number	Publication Date
NO960251D0 NO960251D0 (no)	1996-01-22
NO960251L true NO960251L (no)	1996-03-22
NO314453B1 NO314453B1 (no)	2003-03-24

Family

ID=10739292

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO19960251A NO314453B1 (no)	1993-07-23	1996-01-22	Vitamin D-analoger

Country Status (20)

Country	Link
US (2)	US5872140A (no)
EP (1)	EP0710227B1 (no)
JP (1)	JPH09500637A (no)
KR (1)	KR100321415B1 (no)
CN (1)	CN1043883C (no)
AT (1)	ATE172451T1 (no)
AU (1)	AU690565B2 (no)
CA (1)	CA2167837A1 (no)
CZ (1)	CZ20796A3 (no)
DE (1)	DE69414115T2 (no)
DK (1)	DK0710227T3 (no)
ES (1)	ES2125466T3 (no)
FI (1)	FI113535B (no)
GB (1)	GB9315253D0 (no)
HU (1)	HU221597B (no)
IL (1)	IL110415A (no)
NO (1)	NO314453B1 (no)
NZ (1)	NZ268659A (no)
WO (1)	WO1995003273A1 (no)
ZA (1)	ZA945427B (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE19619036A1 (de)	1996-04-30	1997-11-13	Schering Ag	Neue Vitamin D-Derivate mit carbo- oder heterocyclischen Substituenten an C-25, Verfahren zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
DE19935771A1 (de) *	1999-07-23	2001-02-01	Schering Ag	Neue Vitamin D-Derivate mit cyclischen Substrukturen in den Seitenketten, Verfahren und Zwischenprodukte zu ihrer Herstellung und die Verwendung zur Herstellung von Arzneimitteln
CA2385755C (en)	1999-09-29	2007-02-06	Colotech A/S	Prevention of colorectal cancer
US6703380B2 (en)	1999-09-29	2004-03-09	Colotech A/S	Prevention of cancer
US6989377B2 (en)	1999-12-21	2006-01-24	Wisconsin Alumni Research Foundation	Treating vitamin D responsive diseases
US6358939B1 (en)	1999-12-21	2002-03-19	Northern Lights Pharmaceuticals, Llc	Use of biologically active vitamin D compounds for the prevention and treatment of inflammatory bowel disease
US6555573B2 (en) *	2000-12-21	2003-04-29	The Quigley Corporation	Method and composition for the topical treatment of diabetic neuropathy
US20030105031A1 (en) *	2001-11-06	2003-06-05	Rosenbloom Richard A.	Methods for the treatment of skin disorders
US7435725B2 (en) *	2001-11-06	2008-10-14	The Quigly Corporation	Oral compositions and methods for prevention, reduction and treatment of radiation injury
US20030118536A1 (en) *	2001-11-06	2003-06-26	Rosenbloom Richard A.	Topical compositions and methods for treatment of adverse effects of ionizing radiation
US20030105027A1 (en) *	2001-11-06	2003-06-05	Rosenbloom Richard A.	Nutritional supplements and methods for prevention, reduction and treatment of radiation injury
US6974592B2 (en) *	2002-04-11	2005-12-13	Ocean Nutrition Canada Limited	Encapsulated agglomeration of microcapsules and method for the preparation thereof
AU2003283101B2 (en) *	2002-11-04	2008-12-11	Dsm Nutritional Products Ag	Microcapsules having multiple shells and method for the preparation thereof
US7083813B2 (en) *	2002-11-06	2006-08-01	The Quigley Corporation	Methods for the treatment of peripheral neural and vascular ailments
US8034450B2 (en) *	2005-01-21	2011-10-11	Ocean Nutrition Canada Limited	Microcapsules and emulsions containing low bloom gelatin and methods of making and using thereof
CA2596023A1 (en) *	2005-01-27	2006-11-09	Ocean Nutrition Canada Ltd.	Fatty acid-benzenediol derivatives and methods of making and using thereof
CA2556520C (en) *	2005-01-27	2008-10-28	Ocean Nutrition Canada Ltd.	Chromium-fatty acid compounds and methods of making and using thereof
US9968120B2 (en) *	2006-05-17	2018-05-15	Dsm Nutritional Products Ag	Homogenized formulations containing microcapsules and methods of making and using thereof
EP2007224A2 (en) *	2006-04-07	2008-12-31	Ocean Nutrition Canada Limited	Emulsions and microcapsules with substances having low interfacial tension, methods of making and using thereof
MX306461B (es) *	2006-06-05	2013-01-07	Ocean Nutrition Canada Ltd	Microcapsulas con cubiertas mejoradas
KR101454942B1 (ko)	2007-01-10	2014-10-27	디에스엠 뉴트리셔널 프라덕츠 아게	채식주의용 마이크로캡슐
US20090018151A1 (en) *	2007-02-23	2009-01-15	Ezekiel Fink	Topical Treatment of Peripheral diabetic complications
WO2010088304A1 (en)	2009-01-27	2010-08-05	Cytotech Labs, Llc	Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
KR101880032B1 (ko)	2009-08-14	2018-07-20	베르그 엘엘씨	탈모증 치료용 비타민 ｄ3 및 이의 유사체들
WO2012158794A1 (en)	2011-05-17	2012-11-22	Wisconsin Alumni Research Foundation	N-cyclopropyl-(20r)-2-methylene-19,26,27-trinor-25-aza-vitamin d analogs and their uses
SG10201709894RA (en)	2013-05-29	2018-01-30	Berg Llc	Preventing or mitigating chemotherapy induced alopecia using vitamin d
CN104926739B (zh) *	2015-06-09	2017-06-27	南京理工大学	基于氮杂环修饰的维生素d2衍生物、合成及应用
US10548908B2 (en)	2016-09-15	2020-02-04	Nostopharma, LLC	Compositions and methods for preventing and treating heterotopic ossification and pathologic calcification

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB2114570B (en) *	1981-11-02	1985-08-07	Res Inst Medicine Chem	Chemical compounds
DE4141746A1 (de) *	1991-12-13	1993-06-17	Schering Ag	20-methyl-substituierte vitamin d-derivate
IL107185A (en) *	1992-10-06	1998-02-22	Schering Ag	Vitamin d, 25-carboxylic acid derivatives and pharmaceutical compositions containing the same
US5446635A (en) *	1993-06-24	1995-08-29	Quarton, Inc.	Laser assembly for marking a line on a workpiece for guiding a cutting tool

1993
- 1993-07-23 GB GB939315253A patent/GB9315253D0/en active Pending
1994
- 1994-07-22 ES ES94921070T patent/ES2125466T3/es not_active Expired - Lifetime
- 1994-07-22 AT AT94921070T patent/ATE172451T1/de not_active IP Right Cessation
- 1994-07-22 CA CA002167837A patent/CA2167837A1/en not_active Abandoned
- 1994-07-22 EP EP94921070A patent/EP0710227B1/en not_active Expired - Lifetime
- 1994-07-22 NZ NZ268659A patent/NZ268659A/en unknown
- 1994-07-22 ZA ZA945427A patent/ZA945427B/xx unknown
- 1994-07-22 JP JP7505021A patent/JPH09500637A/ja not_active Ceased
- 1994-07-22 CN CN94193108A patent/CN1043883C/zh not_active Expired - Fee Related
- 1994-07-22 DE DE69414115T patent/DE69414115T2/de not_active Expired - Fee Related
- 1994-07-22 HU HU9600136A patent/HU221597B/hu not_active IP Right Cessation
- 1994-07-22 KR KR1019960700344A patent/KR100321415B1/ko not_active Expired - Fee Related
- 1994-07-22 DK DK94921070T patent/DK0710227T3/da active
- 1994-07-22 CZ CZ96207A patent/CZ20796A3/cs unknown
- 1994-07-22 WO PCT/GB1994/001587 patent/WO1995003273A1/en not_active Ceased
- 1994-07-22 AU AU71939/94A patent/AU690565B2/en not_active Ceased
- 1994-07-22 IL IL11041594A patent/IL110415A/xx not_active IP Right Cessation
- 1994-07-22 US US08/537,869 patent/US5872140A/en not_active Expired - Fee Related
1996
- 1996-01-22 NO NO19960251A patent/NO314453B1/no not_active IP Right Cessation
- 1996-01-22 FI FI960303A patent/FI113535B/fi not_active IP Right Cessation
1998
- 1998-10-20 US US09/175,311 patent/US6013814A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IL110415A0 (en)	1996-03-31
DK0710227T3 (da)	1999-06-28
DE69414115T2 (de)	1999-04-08
FI113535B (fi)	2004-05-14
JPH09500637A (ja)	1997-01-21
US5872140A (en)	1999-02-16
WO1995003273A1 (en)	1995-02-02
CA2167837A1 (en)	1995-02-02
CZ20796A3 (en)	1996-10-16
CN1043883C (zh)	1999-06-30
NO314453B1 (no)	2003-03-24
EP0710227B1 (en)	1998-10-21
HU9600136D0 (en)	1996-03-28
IL110415A (en)	2000-01-31
FI960303L (fi)	1996-03-22
FI960303A0 (fi)	1996-01-22
HUT73846A (en)	1996-09-30
ZA945427B (en)	1995-08-24
CN1129441A (zh)	1996-08-21
US6013814A (en)	2000-01-11
EP0710227A1 (en)	1996-05-08
GB9315253D0 (en)	1993-09-08
ES2125466T3 (es)	1999-03-01
AU7193994A (en)	1995-02-20
ATE172451T1 (de)	1998-11-15
HU221597B (hu)	2002-11-28
NO960251D0 (no)	1996-01-22
DE69414115D1 (de)	1998-11-26
KR100321415B1 (ko)	2002-11-13
AU690565B2 (en)	1998-04-30
NZ268659A (en)	1996-09-25

Legal Events

Date	Code	Title	Description
2005-05-02	MM1K	Lapsed by not paying the annual fees

Publication	Publication Date	Title
DK0710227T3 (da)	1999-06-28	Vitamin D-analoger
EP0172458A3 (en)	1987-01-07	Novel biologically active compound having anti-prolyl endopeptidase activity
NO995075L (no)	1994-04-29	Steroid-sulfataseinhibitorer
BG103805A (en)	2000-06-30	Trifluoromethylalkylaminotriazolopyrimidines with fungicidal effect
IL74497A0 (en)	1985-06-30	Pharmaceutical compositions and phenyl carbamate derivatives
AU564842B2 (en)	1987-08-27	Pyranyl (or cyclohexyl) methane sulfamates and their use as anticonvulsants
DE69412476D1 (de)	1998-09-17	Vitamin-d-amid-derivate
TR200000272T2 (tr)	2000-09-21	Antitümör ve antimetastaz maddeleri olarak o-ikameli hidrosikumaranon türevleri.
NO981393D0 (no)	1998-03-27	Guanidinoproteasehemmere
FI963754A0 (fi)	1996-09-20	D-vitamiinijohdannaisia
PT837677E (pt)	2006-08-31	Derivados hexa-hidroxibifenilo bromados
FR2720938B1 (fr)	1996-08-30	Composition dermato-cosmétologique et son utilisation.
DE69614552D1 (de)	2001-09-20	MODIFIZIERTE ALPHA-D-GLCP-(1,2)-ALPHA-D-Glcp-(1,3)-ALPHA-D-Glcp-ANALOGE
ITMI931808A1 (it)	1995-02-09	Derivati ossimici dell'acido formilfenilacetamido-cefalosporanico
NO20053117L (no)	2005-06-24	Cyklopenta[c]isoksazol-3-aminer anvendt som materialbeskyttelsesmidler..