NO960307L - Fremgangsmåte ved fremstilling av substituerte 4,6-diamino-5-cyanopyrimidiner - Google Patents

Fremgangsmåte ved fremstilling av substituerte 4,6-diamino-5-cyanopyrimidiner

Info

Publication number: NO960307L
Authority: NO; Norway
Prior art keywords: formula; alkali metal; diamino; give; cyanopyrimidines
Prior art date: 1993-07-26

Application number

NO960307A

Other languages

English (en)

Norwegian (no)

Other versions

NO960307D0 (no

Inventor

Jean-Marie Assercq

Heinz Peter Schwemlein

Jeffrey William Perine

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-07-26

Filing date

1996-01-25

Publication date

1996-01-25

1996-01-25 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1996-01-25 Publication of NO960307D0 publication Critical patent/NO960307D0/no

1996-01-25 Publication of NO960307L publication Critical patent/NO960307L/no

Links

BTVHLEVGNAQTBN-UHFFFAOYSA-N 4,6-diaminopyrimidine-5-carbonitrile Chemical class NC1=NC=NC(N)=C1C#N BTVHLEVGNAQTBN-UHFFFAOYSA-N 0.000 title 1
-1 2-Substituted 4,6-diamino-5-cyanopyrimidines Chemical class 0.000 abstract 4
229910052783 alkali metal Inorganic materials 0.000 abstract 4
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 2
SSBDGGIFOJKRTP-UHFFFAOYSA-N 4,6-diamino-2-chloropyrimidine-5-carbonitrile Chemical compound NC1=NC(Cl)=NC(N)=C1C#N SSBDGGIFOJKRTP-UHFFFAOYSA-N 0.000 abstract 1
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
150000001412 amines Chemical class 0.000 abstract 1
229910021529 ammonia Inorganic materials 0.000 abstract 1
239000012467 final product Substances 0.000 abstract 1
229910000041 hydrogen chloride Inorganic materials 0.000 abstract 1
IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
150000003333 secondary alcohols Chemical class 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/50—Three nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

NO960307A 1993-07-26 1996-01-25 Fremgangsmåte ved fremstilling av substituerte 4,6-diamino-5-cyanopyrimidiner NO960307L (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US9714193A	1993-07-26	1993-07-26
US21098094A	1994-03-21	1994-03-21
PCT/EP1994/002312 WO1995003282A2 (en)	1993-07-26	1994-07-14	Process for the preparation of substituted 4,6-diamino-5-cyanopyrimidines

Publications (2)

Publication Number	Publication Date
NO960307D0 NO960307D0 (no)	1996-01-25
NO960307L true NO960307L (no)	1996-01-25

Family

ID=26792702

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO960307A NO960307L (no)	1993-07-26	1996-01-25	Fremgangsmåte ved fremstilling av substituerte 4,6-diamino-5-cyanopyrimidiner

Country Status (15)

Country	Link
EP (1)	EP0711285A1 (bg)
JP (1)	JPH09500632A (bg)
CN (1)	CN1128024A (bg)
AU (1)	AU7385994A (bg)
BG (1)	BG100366A (bg)
BR (1)	BR9407024A (bg)
CA (1)	CA2166989A1 (bg)
CZ (1)	CZ22496A3 (bg)
FI (1)	FI960332A0 (bg)
HU (1)	HUT73357A (bg)
IL (1)	IL110425A0 (bg)
LV (1)	LV11463B (bg)
NO (1)	NO960307L (bg)
SK (1)	SK10396A3 (bg)
WO (1)	WO1995003282A2 (bg)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6255316B1 (en) *	1997-08-27	2001-07-03	Novartis Animal Health Us, Inc.	Dicyclanil polymorphs and hydrates and their preparation
US8273899B2 (en)	2007-04-19	2012-09-25	Nippon Soda Co., Ltd.	Method for production of N-(2-amino-1,2-dicyanovinyl)imidates, method for production of N-(2-amino-1,2-dicyanovinyl)formamidine, and method for production of aminoimidazole derivatives
CN102250017A (zh) *	2011-06-15	2011-11-23	扬州天和药业有限公司	地昔尼尔的一种合成方法
CN102399193A (zh) *	2011-12-15	2012-04-04	连云港市亚晖医药化工有限公司	4,6-二氨基-2-环丙胺基-5-腈基嘧啶的制备方法
CN104130197A (zh) *	2014-07-29	2014-11-05	华中农业大学	2,4,6-三氨基-5-氰基嘧啶的化学合成方法
CN104649982B (zh) *	2015-02-26	2016-12-07	齐鲁晟华制药有限公司	一种地昔尼尔的制备方法
CN107056655B (zh) *	2017-01-22	2018-12-04	营口三征新科技化工有限公司	一种1-氨基-1-氰氨基-2,2-二氰乙烯钠盐的制备方法
CN106966922B (zh) *	2017-03-28	2020-10-27	中国科学院大学	一种功能化取代的二氰基乙烯类化合物的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1135913B (de) *	1960-11-08	1962-09-06	Bayer Ag	Verfahren zur Herstellung von 2-Methyl-4-amino-5-cyanpyrimidin
US3226424A (en) *	1962-10-03	1965-12-28	Hoffmann La Roche	Process for preparing 2-lower alkoxy-1,1-dicyanoethylene and 2-amino-1,1-dicyanoethylene
US4783468A (en) *	1986-04-30	1988-11-08	Ciba-Geigy Corporation	Insecticidal 5-pyrimidine carbonitriles

1994
- 1994-07-14 SK SK103-96A patent/SK10396A3/sk unknown
- 1994-07-14 EP EP94923734A patent/EP0711285A1/en not_active Withdrawn
- 1994-07-14 CA CA002166989A patent/CA2166989A1/en not_active Abandoned
- 1994-07-14 AU AU73859/94A patent/AU7385994A/en not_active Abandoned
- 1994-07-14 BR BR9407024A patent/BR9407024A/pt not_active Application Discontinuation
- 1994-07-14 CZ CZ96224A patent/CZ22496A3/cs unknown
- 1994-07-14 JP JP7504913A patent/JPH09500632A/ja active Pending
- 1994-07-14 CN CN94192888.8A patent/CN1128024A/zh active Pending
- 1994-07-14 WO PCT/EP1994/002312 patent/WO1995003282A2/en not_active Ceased
- 1994-07-14 HU HU9503959A patent/HUT73357A/hu unknown
- 1994-07-25 IL IL11042594A patent/IL110425A0/xx unknown
1996
- 1996-01-24 FI FI960332A patent/FI960332A0/fi not_active Application Discontinuation
- 1996-01-25 NO NO960307A patent/NO960307L/no unknown
- 1996-02-19 BG BG100366A patent/BG100366A/bg unknown
- 1996-02-26 LV LVP-96-53A patent/LV11463B/en unknown

Also Published As

Publication number	Publication date
WO1995003282A3 (en)	1995-04-13
CN1128024A (zh)	1996-07-31
JPH09500632A (ja)	1997-01-21
CZ22496A3 (en)	1996-04-17
NO960307D0 (no)	1996-01-25
FI960332A7 (fi)	1996-01-24
HUT73357A (en)	1996-07-29
WO1995003282A2 (en)	1995-02-02
CA2166989A1 (en)	1995-02-02
EP0711285A1 (en)	1996-05-15
SK10396A3 (en)	1996-09-04
BR9407024A (pt)	1996-09-10
BG100366A (bg)	1996-07-31
AU7385994A (en)	1995-02-20
IL110425A0 (en)	1994-10-21
LV11463B (en)	1996-12-20
HU9503959D0 (en)	1996-03-28
LV11463A (lv)	1996-08-20
FI960332A0 (fi)	1996-01-24

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