NO961000L - Piperidine derivatives, process for their preparation and drug and preparation containing them - Google Patents

Piperidine derivatives, process for their preparation and drug and preparation containing them

Info

Publication number
NO961000L
NO961000L NO961000A NO961000A NO961000L NO 961000 L NO961000 L NO 961000L NO 961000 A NO961000 A NO 961000A NO 961000 A NO961000 A NO 961000A NO 961000 L NO961000 L NO 961000L
Authority
NO
Norway
Prior art keywords
preparation
piperidine derivatives
drug
preparation containing
methyl
Prior art date
Application number
NO961000A
Other languages
Norwegian (no)
Other versions
NO961000D0 (en
Inventor
Luc Even
Samir Jegham
Gerard Defosse
Michel Aletru
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of NO961000D0 publication Critical patent/NO961000D0/en
Publication of NO961000L publication Critical patent/NO961000L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

Piperidinderivater med den generelle formel (I) (D hvor X representerer et oksygenatom eller en metylengruppe, R, representerer et klor- eller fluoratom eller en metyl, metoksy eller aminogruppe, og R2 og R3 representerer, uavhengig av hverandre, hydrogenatomer eller metylgrupper. Derivatene har terapeutisk anvendelse.Piperidine derivatives of the general formula (I) (D where X represents an oxygen atom or a methylene group, R, represents a chlorine or fluorine atom or a methyl, methoxy or amino group, and R 2 and R 3 independently represent hydrogen atoms or methyl groups. has therapeutic use.

NO961000A 1995-03-13 1996-03-12 Piperidine derivatives, process for their preparation and drug and preparation containing them NO961000L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9502863A FR2731708B1 (en) 1995-03-13 1995-03-13 PIPERIDINE DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR THERAPEUTIC APPLICATION

Publications (2)

Publication Number Publication Date
NO961000D0 NO961000D0 (en) 1996-03-12
NO961000L true NO961000L (en) 1996-09-16

Family

ID=9476960

Family Applications (1)

Application Number Title Priority Date Filing Date
NO961000A NO961000L (en) 1995-03-13 1996-03-12 Piperidine derivatives, process for their preparation and drug and preparation containing them

Country Status (15)

Country Link
EP (1) EP0732334A1 (en)
JP (1) JPH08269058A (en)
KR (1) KR960034205A (en)
CN (1) CN1140174A (en)
AU (1) AU4800896A (en)
CA (1) CA2171579A1 (en)
CZ (1) CZ75496A3 (en)
FR (1) FR2731708B1 (en)
HU (1) HUP9600624A2 (en)
IL (1) IL117455A0 (en)
NO (1) NO961000L (en)
NZ (1) NZ286164A (en)
PL (1) PL313204A1 (en)
SK (1) SK34196A3 (en)
ZA (1) ZA961994B (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP9900606A2 (en) * 1995-09-18 2000-03-28 Glaxo Group Limited 5-HT3 receptor antagonists for the treatment of movement disorders
TW527186B (en) 1996-03-19 2003-04-11 Janssen Pharmaceutica Nv Fused imidazole derivatives as multidrug resistance modulators
FR2801589A1 (en) * 1999-11-25 2001-06-01 Sanofi Synthelabo 2-Aryl quinoline derivatives useful for the treatment of urinary incontinence. venous ulcers, migraine or gastro-intestinal disorders
FR2816619B1 (en) * 2000-11-15 2003-01-31 Sanofi Synthelabo BENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
EP1309594B1 (en) * 2000-08-08 2004-12-15 Sanofi-Aventis Benzimidazole derivatives, preparation and therapeutic use thereof
FR2816942B1 (en) 2000-11-23 2003-05-09 Sanofi Synthelabo BENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
FR2816941B1 (en) * 2000-11-23 2003-01-31 Sanofi Synthelabo BENZIMIDAZOLE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
SG11201506924YA (en) 2013-03-15 2015-09-29 Incyte Corp Tricyclic heterocycles as bet protein inhibitors
EP3019502B1 (en) 2013-07-08 2017-05-17 Incyte Holdings Corporation Tricyclic heterocycles as bet protein inhibitors
WO2015081189A1 (en) 2013-11-26 2015-06-04 Incyte Corporation Bicyclic heterocycles as bet protein inhibitors
US9399640B2 (en) 2013-11-26 2016-07-26 Incyte Corporation Substituted pyrrolo[2,3-c]pyridines and pyrazolo[3,4-c]pyridines as BET protein inhibitors
WO2015095492A1 (en) 2013-12-19 2015-06-25 Incyte Corporation Tricyclic heterocycles as bet protein inhibitors
PL3134403T3 (en) 2014-04-23 2020-07-13 Incyte Corporation 1h-pyrrolo[2,3-c]pyridin-7(6h)-ones and pyrazolo[3,4-c]pyridin-7(6h)-ones as inhibitors of bet proteins
JP6599979B2 (en) 2014-09-15 2019-10-30 インサイト・コーポレイション Tricyclic heterocyclic compounds for use as BET protein inhibitors
WO2017075377A1 (en) 2015-10-29 2017-05-04 Incyte Corporation Amorphous solid form of a bet protein inhibitor
CA3028689A1 (en) 2016-06-20 2017-12-28 Incyte Corporation Crystalline solid forms of a bet inhibitor
US11535633B2 (en) * 2018-06-28 2022-12-27 Jiangsu Hengrui Medicine Co., Ltd. Fused tricyclic heterocycle compounds and therapeutic uses thereof
US11833155B2 (en) 2020-06-03 2023-12-05 Incyte Corporation Combination therapy for treatment of myeloproliferative neoplasms

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2674855B1 (en) * 1991-04-03 1994-01-14 Synthelabo PIPERIDINE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.
FR2696176B1 (en) * 1992-09-28 1994-11-10 Synthelabo Piperidine derivatives, their preparation and their therapeutic application.
FR2710915B1 (en) * 1993-10-04 1995-11-24 Synthelabo Piperidine derivatives, their preparation and their therapeutic use.

Also Published As

Publication number Publication date
CN1140174A (en) 1997-01-15
ZA961994B (en) 1996-09-03
FR2731708B1 (en) 1997-04-30
IL117455A0 (en) 1996-07-23
AU4800896A (en) 1996-09-26
HU9600624D0 (en) 1996-05-28
CA2171579A1 (en) 1996-09-14
CZ75496A3 (en) 1996-10-16
FR2731708A1 (en) 1996-09-20
KR960034205A (en) 1996-10-22
SK34196A3 (en) 1996-10-02
PL313204A1 (en) 1996-09-16
HUP9600624A2 (en) 1997-01-28
EP0732334A1 (en) 1996-09-18
JPH08269058A (en) 1996-10-15
NO961000D0 (en) 1996-03-12
NZ286164A (en) 1996-11-26

Similar Documents

Publication Publication Date Title
NO961000L (en) Piperidine derivatives, process for their preparation and drug and preparation containing them
NO944911L (en) Non-peptide takykininreseptorantagonister
HUP0101999A2 (en) 4-hydroxyquinoline-3-carboxamides and hydrazides use of them and pharmaceutical compositions containing them
HUP0004434A2 (en) Adamantane derivatives and pharmaceuticals containing them
NO996108L (en) 9 oksinerytromycinderivater
HUP0002347A2 (en) Use of hydantoin, oxazole and pyrrole derivatives for the preparation of pharmaceutical compositions inflammatory disease treating
CY2488B1 (en) New 4-(oxyalkoxyphenyl)-3-oxy-piperidines for trea.
MY119150A (en) Azetidine derivatives, their preparation and medicaments containing them
NO922851L (en) TRIFLUORMETHYL BENZYL PHOSPHONATES USED FOR TREATMENT OF OSTEPOROSE
HUP0401886A2 (en) Piperidine derivatives useful as modulators of chemokine receptor activity, process for their preparation and pharmaceutical compositions containing them
DE3576690D1 (en) PYRIMIDOPYRIMIDINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, THE PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND THEIR USE AS AN ANTI-ALLERGIC AGENT.
HUP9802762A2 (en) Diphenylmethylene piperidine derivatives, pharmaceutical compositions containing them, process for producing them and their use
NO934485D0 (en) Procedure for Preparation of Baccatin-III and 10-Des-Acetyl-Baccati-III Derivatives
NO964667L (en) Purin-6-one derivatives
FR2712591B1 (en) New arylpiperazines derived from indole, their preparation and their therapeutic use.
DK0424244T3 (en) 3-aryl-oxazolidinone derivatives, process for their preparation and therapeutic use thereof
NO990463L (en) Azabicyclic carbamoyloxymutiline derivatives for antibacterial use
HUT56092A (en) Process for producing 2-amino-pyrimidine-4-carboxamide derivatives and pharmaceutical compositions containing them
ES2073258T3 (en) NEW DERIVATIVES OF THE UREA, ITS PREPARATION AND ITS APPLICATION IN THERAPEUTICS.
GR920100570A (en) PRODUCTION 3 (2H) -PYRIDAZINONIS AND METHOD FOR THEIR EXAMPLE.
DK0558677T3 (en) Biologically active amines
HUP9904294A2 (en) Topiramate derivatives use for producing medicament useful in the treatment of neuropathic pain
HUP9701660A2 (en) 10,13,15-trioxatricyclo[9.2.1.1.9.6]pentadekanon derivatives, process for producing them, and pharmaceutical compositions containing them
ZA9510908B (en) Pharmaceutical compounds
HUP0104224A2 (en) Certain substituted caprolactams, pharmaceutical compositions containing them and their use in treating tumors